-
1
-
-
84891804220
-
MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
-
Rawlings N.D., Waller M., Barrett A.J., Bateman A. MEROPS: the database of proteolytic enzymes, their substrates and inhibitors. Nucleic Acids Res. 2014, 42:503-509.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 503-509
-
-
Rawlings, N.D.1
Waller, M.2
Barrett, A.J.3
Bateman, A.4
-
2
-
-
84911444179
-
Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes
-
Ezkurdia I., Juan D., Rodriguez J.M., Frankish A., Diekhans M., Harrow J., et al. Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes. Hum. Mol. Genet. 2014, 23:5866-5878.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 5866-5878
-
-
Ezkurdia, I.1
Juan, D.2
Rodriguez, J.M.3
Frankish, A.4
Diekhans, M.5
Harrow, J.6
-
3
-
-
0036302814
-
Protease degradomics: a new challenge for proteomics
-
López-Otín C., Overall C.M. Protease degradomics: a new challenge for proteomics. Nat. Rev. Mol. Cell Biol. 2002, 3:509-519.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 509-519
-
-
López-Otín, C.1
Overall, C.M.2
-
4
-
-
0037803570
-
Human and mouse proteases: a comparative genomic approach
-
Puente X.S., Sánchez L.M., Overall C.M., López-Otín C. Human and mouse proteases: a comparative genomic approach. Nat. Rev. Genet. 2003, 4:544-558.
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 544-558
-
-
Puente, X.S.1
Sánchez, L.M.2
Overall, C.M.3
López-Otín, C.4
-
5
-
-
55049133250
-
Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome
-
Doucet A., Butler G.S., Rodríguez D., Prudova A., Overall C.M. Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome. Mol. Cell. Proteomics 2008, 7:1925-1951.
-
(2008)
Mol. Cell. Proteomics
, vol.7
, pp. 1925-1951
-
-
Doucet, A.1
Butler, G.S.2
Rodríguez, D.3
Prudova, A.4
Overall, C.M.5
-
6
-
-
84859366447
-
Protease signalling: the cutting edge
-
Turk B., Turk D., Turk V. Protease signalling: the cutting edge. EMBO J. 2012, 31:1630-1643.
-
(2012)
EMBO J.
, vol.31
, pp. 1630-1643
-
-
Turk, B.1
Turk, D.2
Turk, V.3
-
7
-
-
77950012622
-
The regulatory crosstalk between kinases and proteases in cancer
-
López-Otín C., Hunter T. The regulatory crosstalk between kinases and proteases in cancer. Nat. Rev. Cancer 2010, 10:278-292.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 278-292
-
-
López-Otín, C.1
Hunter, T.2
-
8
-
-
79953163995
-
Proteolytic networks in cancer
-
Mason S.D., Joyce J.A. Proteolytic networks in cancer. Trends Cell Biol. 2011, 21:228-237.
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 228-237
-
-
Mason, S.D.1
Joyce, J.A.2
-
9
-
-
34648815810
-
Emerging roles of proteases in tumour suppression
-
López-Otín C., Matrisian L.M. Emerging roles of proteases in tumour suppression. Nat. Rev. Cancer 2007, 7:800-808.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 800-808
-
-
López-Otín, C.1
Matrisian, L.M.2
-
11
-
-
84874355076
-
Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies
-
Akers J.C., Gonda D., Kim R., Carter B.S., Chen C.C. Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies. J. Neurooncol. 2013, 113:1-11.
-
(2013)
J. Neurooncol.
, vol.113
, pp. 1-11
-
-
Akers, J.C.1
Gonda, D.2
Kim, R.3
Carter, B.S.4
Chen, C.C.5
-
12
-
-
84905273466
-
Engulfing losers by winners in cancer: do cancer stem cells catch eat-me signals from noncancer stem cells?
-
Nakano I. Engulfing losers by winners in cancer: do cancer stem cells catch eat-me signals from noncancer stem cells?. Future Oncol. 2014, 10:1335-1338.
-
(2014)
Future Oncol.
, vol.10
, pp. 1335-1338
-
-
Nakano, I.1
-
13
-
-
85010225935
-
Lysosome function in the regulation of the secretory process in cells of the anterior pituitary gland
-
Smith R.E., Farquhar M.G. Lysosome function in the regulation of the secretory process in cells of the anterior pituitary gland. J. Cell Biol. 1966, 1:319-347.
-
(1966)
J. Cell Biol.
, vol.1
, pp. 319-347
-
-
Smith, R.E.1
Farquhar, M.G.2
-
14
-
-
84878643872
-
Lysosomal cell death at a glance
-
Aits S., Jäättelä M. Lysosomal cell death at a glance. J. Cell Sci. 2013, 126:1905-1912.
-
(2013)
J. Cell Sci.
, vol.126
, pp. 1905-1912
-
-
Aits, S.1
Jäättelä, M.2
-
15
-
-
18244399644
-
Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy
-
Prasmickaite L., Høgset A., Selbo P.K., Engesaeter B.Ø., Hellum M., Berg K. Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy. Br. J. Cancer 2002, 86:652-657.
-
(2002)
Br. J. Cancer
, vol.86
, pp. 652-657
-
-
Prasmickaite, L.1
Høgset, A.2
Selbo, P.K.3
Engesaeter, B.Ø.4
Hellum, M.5
Berg, K.6
-
16
-
-
84908275360
-
Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
-
Boelens M.C., Wu T.J., Nabet B.Y., Xu B., Qiu Y., Yoon T., et al. Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 2014, 159:499-513.
-
(2014)
Cell
, vol.159
, pp. 499-513
-
-
Boelens, M.C.1
Wu, T.J.2
Nabet, B.Y.3
Xu, B.4
Qiu, Y.5
Yoon, T.6
-
17
-
-
38649111363
-
Cysteine cathepsins: cellular roadmap to different functions
-
Brix K., Dunkhorst A., Mayer K., Jordans S. Cysteine cathepsins: cellular roadmap to different functions. Biochimie 2008, 90:194-207.
-
(2008)
Biochimie
, vol.90
, pp. 194-207
-
-
Brix, K.1
Dunkhorst, A.2
Mayer, K.3
Jordans, S.4
-
18
-
-
82755161948
-
Cysteine cathepsins: from structure, function and regulation to new frontiers
-
Turk V., Stoka V., Vasiljeva O., Renko M., Sun T., Turk B., et al. Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim. Biophys. Acta 2012, 1824:68-88.
-
(2012)
Biochim. Biophys. Acta
, vol.1824
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
Renko, M.4
Sun, T.5
Turk, B.6
-
19
-
-
0038835365
-
Thyropins - new structurally related proteinase inhibitors
-
Lenarčič B., Bevec T. Thyropins - new structurally related proteinase inhibitors. Biol. Chem. 1998, 379:105-111.
-
(1998)
Biol. Chem.
, vol.379
, pp. 105-111
-
-
Lenarčič, B.1
Bevec, T.2
-
20
-
-
0032506007
-
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
-
Saftig P., Hunziker E., Wehmeyer O., Jones S., Boyde A., Rommerskirch W., et al. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:13453-13458.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 13453-13458
-
-
Saftig, P.1
Hunziker, E.2
Wehmeyer, O.3
Jones, S.4
Boyde, A.5
Rommerskirch, W.6
-
21
-
-
79960063041
-
Thyroid cathepsin K: roles in physiology and thyroid disease
-
Dauth S., Arampatzidou M., Rehders M., Yu D.M.T., Führer D., Brix K. Thyroid cathepsin K: roles in physiology and thyroid disease. Clin. Rev. Bone Miner. Metab. 2011, 9:94-106.
-
(2011)
Clin. Rev. Bone Miner. Metab.
, vol.9
, pp. 94-106
-
-
Dauth, S.1
Arampatzidou, M.2
Rehders, M.3
Yu, D.M.T.4
Führer, D.5
Brix, K.6
-
22
-
-
66949121118
-
Expression and regulation of cathepsin K in skin fibroblasts
-
Quintanilla-Dieck M.J., Codriansky K., Keady M., Bhawan J., Rünger T.M. Expression and regulation of cathepsin K in skin fibroblasts. Exp. Dermatol. 2009, 18:596-602.
-
(2009)
Exp. Dermatol.
, vol.18
, pp. 596-602
-
-
Quintanilla-Dieck, M.J.1
Codriansky, K.2
Keady, M.3
Bhawan, J.4
Rünger, T.M.5
-
23
-
-
21044440422
-
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues
-
Kos J., Sekirnik A., Premzl A., Bergant V.Z., Langerholc T., Turk B., et al. Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues. Exp. Cell Res. 2005, 306:103-113.
-
(2005)
Exp. Cell Res.
, vol.306
, pp. 103-113
-
-
Kos, J.1
Sekirnik, A.2
Premzl, A.3
Bergant, V.Z.4
Langerholc, T.5
Turk, B.6
-
24
-
-
84919710675
-
Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells
-
Perišić Nanut M., Sabotič J., Jewett A., Kos J. Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells. Front. Immunol. 2014, 5:7-9.
-
(2014)
Front. Immunol.
, vol.5
, pp. 7-9
-
-
Perišić Nanut, M.1
Sabotič, J.2
Jewett, A.3
Kos, J.4
-
25
-
-
0024604767
-
Degradation of laminin by human tumor cathepsin B
-
Lah T.T., Buck M.R., Honn K.V., Crissman J.D., Rao N.C., Liotta L.A., et al. Degradation of laminin by human tumor cathepsin B. Clin. Exp. Metastasis 1989, 7:461-468.
-
(1989)
Clin. Exp. Metastasis
, vol.7
, pp. 461-468
-
-
Lah, T.T.1
Buck, M.R.2
Honn, K.V.3
Crissman, J.D.4
Rao, N.C.5
Liotta, L.A.6
-
26
-
-
33749017931
-
Cysteine cathepsins: multifunctional enzymes in cancer
-
Mohamed M.M., Sloane B.F. Cysteine cathepsins: multifunctional enzymes in cancer. Nat. Rev. Cancer 2006, 6:764-775.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
27
-
-
49649123891
-
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues
-
Droga-Mazovec G., Bojic L., Petelin A., Ivanova S., Romih R., Repnik U., et al. Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues. J. Biol. Chem. 2008, 283:19140-19150.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 19140-19150
-
-
Droga-Mazovec, G.1
Bojic, L.2
Petelin, A.3
Ivanova, S.4
Romih, R.5
Repnik, U.6
-
28
-
-
77955957035
-
Nuclear cysteine cathepsin variants in thyroid carcinoma cells
-
Tedelind S., Poliakova K., Valeta A., Hunegnaw R., Yemanaberhan E.L., Heldin N.E., et al. Nuclear cysteine cathepsin variants in thyroid carcinoma cells. Biol. Chem. 2010, 391:923-935.
-
(2010)
Biol. Chem.
, vol.391
, pp. 923-935
-
-
Tedelind, S.1
Poliakova, K.2
Valeta, A.3
Hunegnaw, R.4
Yemanaberhan, E.L.5
Heldin, N.E.6
-
29
-
-
1942470581
-
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor
-
Goulet B., Baruch A., Moon N.-S., Poirier M., Sansregret L., Erickson A., et al. A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Cell 2004, 14:207-219.
-
(2004)
Cell
, vol.14
, pp. 207-219
-
-
Goulet, B.1
Baruch, A.2
Moon, N.-S.3
Poirier, M.4
Sansregret, L.5
Erickson, A.6
-
30
-
-
53549094681
-
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation
-
Duncan E.M., Muratore-Schroeder T.L., Cook R.G., Garcia B.A., Shabanowitz J., Hunt D.F., et al. Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell 2008, 135:284-294.
-
(2008)
Cell
, vol.135
, pp. 284-294
-
-
Duncan, E.M.1
Muratore-Schroeder, T.L.2
Cook, R.G.3
Garcia, B.A.4
Shabanowitz, J.5
Hunt, D.F.6
-
31
-
-
58149260198
-
Histone H3 tail clipping regulates gene expression
-
Santos-Rosa H., Kirmizis A., Nelson C., Bartke T., Saksouk N., Cote J., et al. Histone H3 tail clipping regulates gene expression. Nat. Struct. Mol. Biol. 2008, 16:17-22.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 17-22
-
-
Santos-Rosa, H.1
Kirmizis, A.2
Nelson, C.3
Bartke, T.4
Saksouk, N.5
Cote, J.6
-
32
-
-
80051546729
-
Inhibition of cathepsin L lowers the apoptotic threshold of glioblastoma cells by up-regulating p53 and transcription of caspases 3 and 7
-
Kenig S., Frangež R., Pucer A., Lah T. Inhibition of cathepsin L lowers the apoptotic threshold of glioblastoma cells by up-regulating p53 and transcription of caspases 3 and 7. Apoptosis 2011, 16:671-682.
-
(2011)
Apoptosis
, vol.16
, pp. 671-682
-
-
Kenig, S.1
Frangež, R.2
Pucer, A.3
Lah, T.4
-
33
-
-
84923291781
-
Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo
-
Tholen M., Hillebrand L.E., Tholen S., Sedelmeier O., Arnold S.J., Reinheckel T. Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo. Nat. Commun. 2014, 5:4931.
-
(2014)
Nat. Commun.
, vol.5
, pp. 4931
-
-
Tholen, M.1
Hillebrand, L.E.2
Tholen, S.3
Sedelmeier, O.4
Arnold, S.J.5
Reinheckel, T.6
-
34
-
-
38849159247
-
Biochemical properties and regulation of cathepsin K activity
-
Lecaille F., Brömme D., Lalmanach G. Biochemical properties and regulation of cathepsin K activity. Biochimie 2008, 90:208-226.
-
(2008)
Biochimie
, vol.90
, pp. 208-226
-
-
Lecaille, F.1
Brömme, D.2
Lalmanach, G.3
-
35
-
-
84879769698
-
Role of cysteine cathepsins in extracellular proteolysis
-
Springer Berlin Heidelberg, Berlin, Heidelberg, W.C. Parks, R.P. Mecham (Eds.)
-
Brömme D., Wilson S. Role of cysteine cathepsins in extracellular proteolysis. Extracellular Matrix Degradation 2011, 23-52. Springer Berlin Heidelberg, Berlin, Heidelberg. W.C. Parks, R.P. Mecham (Eds.).
-
(2011)
Extracellular Matrix Degradation
, pp. 23-52
-
-
Brömme, D.1
Wilson, S.2
-
36
-
-
1242294466
-
Regulation of collagenase activities of human cathepsins by glycosaminoglycans
-
Li Z., Yasuda Y., Li W., Bogyo M.S., Katz N., Gordon R.E., et al. Regulation of collagenase activities of human cathepsins by glycosaminoglycans. J. Biol. Chem. 2004, 279:5470-5479.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5470-5479
-
-
Li, Z.1
Yasuda, Y.2
Li, W.3
Bogyo, M.S.4
Katz, N.5
Gordon, R.E.6
-
37
-
-
77954737401
-
Conformational flexibility and allosteric regulation of cathepsin K
-
Novinec M., Kovacic L., Lenarcic B., Baici A. Conformational flexibility and allosteric regulation of cathepsin K. Biochem. J. 2010, 429:379-389.
-
(2010)
Biochem. J.
, vol.429
, pp. 379-389
-
-
Novinec, M.1
Kovacic, L.2
Lenarcic, B.3
Baici, A.4
-
38
-
-
52049126668
-
The crystal and molecular structures of a cathepsin K: chondroitin sulfate complex
-
Li Z., Kienetz M., Cherney M.M., James M.N.G., Brömme D. The crystal and molecular structures of a cathepsin K: chondroitin sulfate complex. J. Mol. Biol. 2008, 383:78-91.
-
(2008)
J. Mol. Biol.
, vol.383
, pp. 78-91
-
-
Li, Z.1
Kienetz, M.2
Cherney, M.M.3
James, M.N.G.4
Brömme, D.5
-
39
-
-
0033610853
-
The collagenolytic activity of cathepsin K is unique among mammalian proteinases
-
Garnero P., Borel O., Byrjalsen I., Ferreras M., Drake F.H., McQueney M.S., et al. The collagenolytic activity of cathepsin K is unique among mammalian proteinases. J. Biol. Chem. 1998, 273:32347-32352.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32347-32352
-
-
Garnero, P.1
Borel, O.2
Byrjalsen, I.3
Ferreras, M.4
Drake, F.H.5
McQueney, M.S.6
-
40
-
-
84903543514
-
Cysteine cathepsins and extracellular matrix degradation
-
Fonović M., Turk B. Cysteine cathepsins and extracellular matrix degradation. Biochim. Biophys. Acta 2014, 1840:2560-2570.
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 2560-2570
-
-
Fonović, M.1
Turk, B.2
-
41
-
-
0038486755
-
Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation
-
Hou W.-S., Li Z., Büttner F.H., Bartnik E., Brömme D. Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation. Biol. Chem. 2003, 384:891-897.
-
(2003)
Biol. Chem.
, vol.384
, pp. 891-897
-
-
Hou, W.-S.1
Li, Z.2
Büttner, F.H.3
Bartnik, E.4
Brömme, D.5
-
42
-
-
84881539601
-
Cathepsin K: a unique collagenolytic cysteine peptidase
-
Novinec M., Lenarčič B. Cathepsin K: a unique collagenolytic cysteine peptidase. Biol. Chem. 2013, 394:1163-1179.
-
(2013)
Biol. Chem.
, vol.394
, pp. 1163-1179
-
-
Novinec, M.1
Lenarčič, B.2
-
43
-
-
67649628133
-
Cathepsin K inhibitors for osteoporosis and potential off-target effects
-
Brömme D., Lecaille F. Cathepsin K inhibitors for osteoporosis and potential off-target effects. Expert Opin. Investig. Drugs 2011, 18:585-600.
-
(2011)
Expert Opin. Investig. Drugs
, vol.18
, pp. 585-600
-
-
Brömme, D.1
Lecaille, F.2
-
44
-
-
33748042274
-
Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone
-
Everts V., Korper W., Hoeben K.A., Jansen I.D.C., Brömme D., Cleutjens K.B.J.M., et al. Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone. J. Bone Miner. Res. 2006, 21:1399-1408.
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 1399-1408
-
-
Everts, V.1
Korper, W.2
Hoeben, K.A.3
Jansen, I.D.C.4
Brömme, D.5
Cleutjens, K.B.J.M.6
-
45
-
-
0025776952
-
Selective inhibition of cysteine proteinases by Z-Phe-AlaCH2F suppresses digestion of collagen by fibroblasts and osteoclasts
-
Van Noorden C.J.F., Everts V. Selective inhibition of cysteine proteinases by Z-Phe-AlaCH2F suppresses digestion of collagen by fibroblasts and osteoclasts. Biochem. Biophys. Res. Commun. 1991, 178:178-184.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.178
, pp. 178-184
-
-
Van Noorden, C.J.F.1
Everts, V.2
-
46
-
-
0035185895
-
Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation
-
Hou W.S., Li Z., Gordon R.E., Chan K., Klein M.J., Levy R., et al. Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation. Am. J. Pathol. 2001, 159:2167-2177.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 2167-2177
-
-
Hou, W.S.1
Li, Z.2
Gordon, R.E.3
Chan, K.4
Klein, M.J.5
Levy, R.6
-
47
-
-
33744983304
-
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
-
Kollet O., Dar A., Shivtiel S., Kalinkovich A., Lapid K., Sztainberg Y., et al. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat. Med. 2006, 12:657-664.
-
(2006)
Nat. Med.
, vol.12
, pp. 657-664
-
-
Kollet, O.1
Dar, A.2
Shivtiel, S.3
Kalinkovich, A.4
Lapid, K.5
Sztainberg, Y.6
-
48
-
-
33846206883
-
Role of cathepsin K in the turnover of the dermal extracellular matrix during scar formation
-
Rünger T.M., Quintanilla-Dieck M.J., Bhawan J. Role of cathepsin K in the turnover of the dermal extracellular matrix during scar formation. J. Invest. Dermatol. 2007, 127:293-297.
-
(2007)
J. Invest. Dermatol.
, vol.127
, pp. 293-297
-
-
Rünger, T.M.1
Quintanilla-Dieck, M.J.2
Bhawan, J.3
-
49
-
-
0032145836
-
Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells
-
Sukhova G.K., Shi G.P., Simon D.I., Chapman H.A., Libby P. Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells. J. Clin. Invest. 1998, 102:576-583.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 576-583
-
-
Sukhova, G.K.1
Shi, G.P.2
Simon, D.I.3
Chapman, H.A.4
Libby, P.5
-
50
-
-
0344643430
-
Identification of cathepsin K as a novel marker of adiposity in white adipose tissue
-
Chiellini C., Costa M., Novelli S.E., Amri E.-Z., Benzi L., Bertacca A., et al. Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. J. Cell. Physiol. 2003, 195:309-321.
-
(2003)
J. Cell. Physiol.
, vol.195
, pp. 309-321
-
-
Chiellini, C.1
Costa, M.2
Novelli, S.E.3
Amri, E.-Z.4
Benzi, L.5
Bertacca, A.6
-
51
-
-
0032080113
-
Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix
-
Kafienah W., Brömme D., Buttle D.J., Croucher L.J., Hollander A.P. Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix. Biochemistry 1998, 331:727-732.
-
(1998)
Biochemistry
, vol.331
, pp. 727-732
-
-
Kafienah, W.1
Brömme, D.2
Buttle, D.J.3
Croucher, L.J.4
Hollander, A.P.5
-
52
-
-
0033109243
-
Expression of cathepsin K in lung epithelial cells
-
Bühling F., Gerber A., Häckel C., Krüger S., Köhnlein T., Brömme D., et al. Expression of cathepsin K in lung epithelial cells. Am. J. Respir. Cell Mol. Biol. 1999, 20:612-619.
-
(1999)
Am. J. Respir. Cell Mol. Biol.
, vol.20
, pp. 612-619
-
-
Bühling, F.1
Gerber, A.2
Häckel, C.3
Krüger, S.4
Köhnlein, T.5
Brömme, D.6
-
53
-
-
33744771928
-
The regulation of cathepsin K gene expression
-
Troen B.R. The regulation of cathepsin K gene expression. Ann. N. Y. Acad. Sci. 2006, 1068:165-172.
-
(2006)
Ann. N. Y. Acad. Sci.
, vol.1068
, pp. 165-172
-
-
Troen, B.R.1
-
54
-
-
0032886694
-
Expression of cathepsin K in the human embryo and fetus
-
Häckel C., Krüger S., Bühling F., Brömme D., Franke K., Schütze A., et al. Expression of cathepsin K in the human embryo and fetus. Dev. Dyn. 1999, 216:89-95.
-
(1999)
Dev. Dyn.
, vol.216
, pp. 89-95
-
-
Häckel, C.1
Krüger, S.2
Bühling, F.3
Brömme, D.4
Franke, K.5
Schütze, A.6
-
55
-
-
71049188177
-
Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions
-
Jordans S., Jenko-Kokalj S., Kühl N.M., Tedelind S., Sendt W., Brömme D., et al. Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions. BMC Biochem. 2009, 10:23.
-
(2009)
BMC Biochem.
, vol.10
, pp. 23
-
-
Jordans, S.1
Jenko-Kokalj, S.2
Kühl, N.M.3
Tedelind, S.4
Sendt, W.5
Brömme, D.6
-
56
-
-
33846946166
-
Cathepsin K and schizophrenia
-
Bernstein H.-G., Bukowska A., Dobrowolny H., Bogerts B., Lendeckel U. Cathepsin K and schizophrenia. Synaspse 2007, 61:252-253.
-
(2007)
Synaspse
, vol.61
, pp. 252-253
-
-
Bernstein, H.-G.1
Bukowska, A.2
Dobrowolny, H.3
Bogerts, B.4
Lendeckel, U.5
-
57
-
-
0021991222
-
Phagocytosis of bone collagen by osteoclasts in two cases of pycnodysostosis
-
Everts V., Aronson D.C., Beertsen W. Phagocytosis of bone collagen by osteoclasts in two cases of pycnodysostosis. Calcif. Tissue Int. 1985, 37:25-31.
-
(1985)
Calcif. Tissue Int.
, vol.37
, pp. 25-31
-
-
Everts, V.1
Aronson, D.C.2
Beertsen, W.3
-
58
-
-
0038304085
-
Cathepsin K deficiency in pycnodysostosis results in accumulation of non-digested phagocytosed collagen in fibroblasts
-
Everts V., Hou W.S., Rialland X., Tigchelaar W., Saftig P., Brömme D., et al. Cathepsin K deficiency in pycnodysostosis results in accumulation of non-digested phagocytosed collagen in fibroblasts. Calcif. Tissue Int. 2003, 73:380-386.
-
(2003)
Calcif. Tissue Int.
, vol.73
, pp. 380-386
-
-
Everts, V.1
Hou, W.S.2
Rialland, X.3
Tigchelaar, W.4
Saftig, P.5
Brömme, D.6
-
59
-
-
85010117171
-
Current research on pycnodysostosis
-
Turan S. Current research on pycnodysostosis. Intractable Rare Dis. Res. 2014, 3:91-93.
-
(2014)
Intractable Rare Dis. Res.
, vol.3
, pp. 91-93
-
-
Turan, S.1
-
60
-
-
33646870167
-
Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass
-
Li C.Y., Jepsen K.J., Majeska R.J., Zhang J., Ni R., Gelb B.D., et al. Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass. J. Bone Miner. Res. 2006, 21:865-875.
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 865-875
-
-
Li, C.Y.1
Jepsen, K.J.2
Majeska, R.J.3
Zhang, J.4
Ni, R.5
Gelb, B.D.6
-
61
-
-
84874542300
-
Advances in menopausal therapy: the tissue-selective estrogen complex
-
Moore A. Advances in menopausal therapy: the tissue-selective estrogen complex. J. Am. Acad. Nurse Pract. 2013, 25:126-133.
-
(2013)
J. Am. Acad. Nurse Pract.
, vol.25
, pp. 126-133
-
-
Moore, A.1
-
62
-
-
0038406146
-
Mechanisms by which nutritional disorders cause reduced bone mass in adults
-
Miller K.K. Mechanisms by which nutritional disorders cause reduced bone mass in adults. J. Women's Heal. 2003, 12:145-150.
-
(2003)
J. Women's Heal.
, vol.12
, pp. 145-150
-
-
Miller, K.K.1
-
64
-
-
0037328317
-
Women awaiting hysterectomy: a qualitative study of issues involved in decisions about oophorectomy
-
Bhavnani V., Clarke A. Women awaiting hysterectomy: a qualitative study of issues involved in decisions about oophorectomy. BJOG Int. J. Obstet. Gynaecol. 2003, 110:168-174.
-
(2003)
BJOG Int. J. Obstet. Gynaecol.
, vol.110
, pp. 168-174
-
-
Bhavnani, V.1
Clarke, A.2
-
65
-
-
84927950374
-
Bone health and chronic kidney disease: another reason for partial nephrectomy?
-
Derweesh I.H. Bone health and chronic kidney disease: another reason for partial nephrectomy?. Bone Heal. Urol. Patients 2014, 24:629-632.
-
(2014)
Bone Heal. Urol. Patients
, vol.24
, pp. 629-632
-
-
Derweesh, I.H.1
-
66
-
-
84869094245
-
The management of osteoporosis in breast cancer survivors
-
Taxel P., Choksi P., Van Poznak C. The management of osteoporosis in breast cancer survivors. Maturitas 2012, 73:275-279.
-
(2012)
Maturitas
, vol.73
, pp. 275-279
-
-
Taxel, P.1
Choksi, P.2
Van Poznak, C.3
-
67
-
-
84862250915
-
Inhibition of cathepsin K for treatment of osteoporosis
-
Boonen S., Rosenberg E., Claessens F., Vanderschueren D., Papapoulos S. Inhibition of cathepsin K for treatment of osteoporosis. Curr. Osteoporos Rep. 2012, 10:73-79.
-
(2012)
Curr. Osteoporos Rep.
, vol.10
, pp. 73-79
-
-
Boonen, S.1
Rosenberg, E.2
Claessens, F.3
Vanderschueren, D.4
Papapoulos, S.5
-
68
-
-
2442694270
-
Pivotal role of cathepsin K in lung fibrosis
-
Bühling F., Röcken C., Brasch F., Hartig R., Yasuda Y., Saftig P., et al. Pivotal role of cathepsin K in lung fibrosis. Am. J. Pathol. 2004, 164:2203-2216.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 2203-2216
-
-
Bühling, F.1
Röcken, C.2
Brasch, F.3
Hartig, R.4
Yasuda, Y.5
Saftig, P.6
-
69
-
-
38849127573
-
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
-
Asagiri M., Hirai T., Kunigami T., Kamano S., Gober H.J., Okamoto K., et al. Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science 2008, 319:624-627.
-
(2008)
Science
, vol.319
, pp. 624-627
-
-
Asagiri, M.1
Hirai, T.2
Kunigami, T.3
Kamano, S.4
Gober, H.J.5
Okamoto, K.6
-
70
-
-
65649133618
-
TLR-3 enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthritis
-
Kim K.W., Cho M.L., Oh H.J., Kim H.R., Kang C.M., Heo Y.M., et al. TLR-3 enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthritis. Immunol. Lett. 2009, 124:9-17.
-
(2009)
Immunol. Lett.
, vol.124
, pp. 9-17
-
-
Kim, K.W.1
Cho, M.L.2
Oh, H.J.3
Kim, H.R.4
Kang, C.M.5
Heo, Y.M.6
-
71
-
-
73649088291
-
Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation
-
Abdollahi-Roodsaz S., Joosten L.A.B., Koenders M.I., van den Brand B.T., van de Loo F.A.J., van den Berg W.B. Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation. Am. J. Pathol. 2009, 175:2004-2013.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 2004-2013
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.B.2
Koenders, M.I.3
van den Brand, B.T.4
van de Loo, F.A.J.5
van den Berg, W.B.6
-
72
-
-
84872341237
-
Hyaluronan inhibits TLR-4 dependent cathepsin K and matrix metalloproteinase 1 expression in human fibroblasts
-
Hirabara S., Kojima T., Takahashi N., Hanabayashi M., Ishiguro N. Hyaluronan inhibits TLR-4 dependent cathepsin K and matrix metalloproteinase 1 expression in human fibroblasts. Biochem. Biophys. Res. Commun. 2013, 430:519-522.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.430
, pp. 519-522
-
-
Hirabara, S.1
Kojima, T.2
Takahashi, N.3
Hanabayashi, M.4
Ishiguro, N.5
-
73
-
-
0033802292
-
Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-deficient human macrophages
-
Punturieri A., Filippov S., Allen E., Caras I., Murray R., Reddy V., et al. Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-deficient human macrophages. J. Exp. Med. 2000, 192:789-799.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 789-799
-
-
Punturieri, A.1
Filippov, S.2
Allen, E.3
Caras, I.4
Murray, R.5
Reddy, V.6
-
74
-
-
79960666941
-
Cathepsin K deficiency in mice induces structural and metabolic changes in the central nervous system that are associated with learning and memory deficits
-
Dauth S., Sîrbulescu R.F., Jordans S., Rehders M., Avena L., Oswald J., et al. Cathepsin K deficiency in mice induces structural and metabolic changes in the central nervous system that are associated with learning and memory deficits. BMC Neurosci. 2011, 12:74.
-
(2011)
BMC Neurosci.
, vol.12
, pp. 74
-
-
Dauth, S.1
Sîrbulescu, R.F.2
Jordans, S.3
Rehders, M.4
Avena, L.5
Oswald, J.6
-
75
-
-
63149086605
-
Cathepsin K generates enkephalin from β-endorph a new mechanism with possible relevance for schizophrenia
-
Lendeckel U., Kähne T., Ten Have S., Bukowska A., Wolke C., Bogerts B., et al. Cathepsin K generates enkephalin from β-endorph a new mechanism with possible relevance for schizophrenia. Neurochem. Int. 2009, 54:410-417.
-
(2009)
Neurochem. Int.
, vol.54
, pp. 410-417
-
-
Lendeckel, U.1
Kähne, T.2
Ten Have, S.3
Bukowska, A.4
Wolke, C.5
Bogerts, B.6
-
76
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.2
-
77
-
-
33644784910
-
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
-
Gocheva V., Zeng W., Ke D., Klimstra D., Reinheckel T., Peters C., et al. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev. 2006, 20:543-556.
-
(2006)
Genes Dev.
, vol.20
, pp. 543-556
-
-
Gocheva, V.1
Zeng, W.2
Ke, D.3
Klimstra, D.4
Reinheckel, T.5
Peters, C.6
-
78
-
-
2342603891
-
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
-
Joyce J.A., Baruch A., Chehade K., Meyer-Morse N., Giraudo E., Tsai F.-Y., et al. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell 2004, 5:443-453.
-
(2004)
Cancer Cell
, vol.5
, pp. 443-453
-
-
Joyce, J.A.1
Baruch, A.2
Chehade, K.3
Meyer-Morse, N.4
Giraudo, E.5
Tsai, F.-Y.6
-
79
-
-
10044296973
-
Cysteine cathepsins in human cancer
-
Jedeszko C., Sloane B.F. Cysteine cathepsins in human cancer. Biol. Chem. 2004, 385:1017-1027.
-
(2004)
Biol. Chem.
, vol.385
, pp. 1017-1027
-
-
Jedeszko, C.1
Sloane, B.F.2
-
80
-
-
37549070672
-
Cysteine cathepsin proteases as pharmacological targets in cancer
-
Palermo C., Joyce J.A. Cysteine cathepsin proteases as pharmacological targets in cancer. Trends Pharmacol. Sci. 2008, 29:22-28.
-
(2008)
Trends Pharmacol. Sci.
, vol.29
, pp. 22-28
-
-
Palermo, C.1
Joyce, J.A.2
-
81
-
-
84902241224
-
Cathepsins mediate tumor metastasis
-
Tan G.-J., Peng Z.-K., Lu J.-P., Tang F.-Q. Cathepsins mediate tumor metastasis. World J. Biol. Chem. 2013, 4:91-101.
-
(2013)
World J. Biol. Chem.
, vol.4
, pp. 91-101
-
-
Tan, G.-J.1
Peng, Z.-K.2
Lu, J.-P.3
Tang, F.-Q.4
-
82
-
-
84923226334
-
Intracellular signaling by cathepsin X: molecular mechanisms and diagnostic and therapeutic opportunities in cancer
-
Kos J., Vižin T., Pečar Fonović U., Pišlar A. Intracellular signaling by cathepsin X: molecular mechanisms and diagnostic and therapeutic opportunities in cancer. Semin. Cancer Biol. 2015, 31:76-83.
-
(2015)
Semin. Cancer Biol.
, vol.31
, pp. 76-83
-
-
Kos, J.1
Vižin, T.2
Pečar Fonović, U.3
Pišlar, A.4
-
83
-
-
0034903658
-
Cathepsin L antisense oligonucleotides in a human osteosarcoma cell line: effects on the invasive phenotype
-
Krueger S., Kellner U., Buehling F., Roessner A. Cathepsin L antisense oligonucleotides in a human osteosarcoma cell line: effects on the invasive phenotype. Cancer Gene Ther. 2001, 8:522-528.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 522-528
-
-
Krueger, S.1
Kellner, U.2
Buehling, F.3
Roessner, A.4
-
84
-
-
0038644575
-
Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors
-
Bervar A., Zajc I., Sever N., Katunuma N., Sloane B.F., Lah T.T. Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors. Biol. Chem. 2005, 384:447-455.
-
(2005)
Biol. Chem.
, vol.384
, pp. 447-455
-
-
Bervar, A.1
Zajc, I.2
Sever, N.3
Katunuma, N.4
Sloane, B.F.5
Lah, T.T.6
-
85
-
-
75049084598
-
Post-translational regulation of cathepsin B, but not of other cysteine cathepsins, contributes to increased glioblastoma cell invasiveness in vitro
-
Gole B., Durán Alonso M.B., Dolenc V., Lah T.T. Post-translational regulation of cathepsin B, but not of other cysteine cathepsins, contributes to increased glioblastoma cell invasiveness in vitro. Pathol. Oncol. Res. 2009, 15:711-723.
-
(2009)
Pathol. Oncol. Res.
, vol.15
, pp. 711-723
-
-
Gole, B.1
Durán Alonso, M.B.2
Dolenc, V.3
Lah, T.T.4
-
86
-
-
75949130595
-
Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9
-
Kenig S., Durán Alonso M.B., Mueller M.M., Lah T.T. Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9. Cancer Lett. 2010, 289:53-61.
-
(2010)
Cancer Lett.
, vol.289
, pp. 53-61
-
-
Kenig, S.1
Durán Alonso, M.B.2
Mueller, M.M.3
Lah, T.T.4
-
87
-
-
84863229642
-
Cathepsin B inhibition limits bone metastasis in breast cancer
-
Withana N.P., Blum G., Sameni M., Slaney C., Anbalagan A., Olive M.B., et al. Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Res. 2012, 72:1199-1209.
-
(2012)
Cancer Res.
, vol.72
, pp. 1199-1209
-
-
Withana, N.P.1
Blum, G.2
Sameni, M.3
Slaney, C.4
Anbalagan, A.5
Olive, M.B.6
-
88
-
-
0026515587
-
Stefins and lysosomal cathepsins B. L and D in human breast carcinoma
-
Lah T.T., Kokalj-Kunovar M., Štrukelj B., Pungerčar J., Barlič-Maganja D., Drobnič-Košorok M., et al. Stefins and lysosomal cathepsins B. L and D in human breast carcinoma. Int. J. Cancer 1992, 50:36-44.
-
(1992)
Int. J. Cancer
, vol.50
, pp. 36-44
-
-
Lah, T.T.1
Kokalj-Kunovar, M.2
Štrukelj, B.3
Pungerčar, J.4
Barlič-Maganja, D.5
Drobnič-Košorok, M.6
-
89
-
-
84865330970
-
The regulation of cysteine cathepsins and cystatins in human gliomas
-
Gole B., Huszthy P.C., Popović M., Jeruc J., Ardebili S.Y., Bjerkvig R., et al. The regulation of cysteine cathepsins and cystatins in human gliomas. Int. J. Cancer 2012, 131:1779-1789.
-
(2012)
Int. J. Cancer
, vol.131
, pp. 1779-1789
-
-
Gole, B.1
Huszthy, P.C.2
Popović, M.3
Jeruc, J.4
Ardebili, S.Y.5
Bjerkvig, R.6
-
90
-
-
71449101202
-
High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas
-
Colin C., Voutsinos-Porche B., Nanni I., Fina F., Metellus P., Intagliata D., et al. High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas. Acta Neuropathol. 2009, 118:745-754.
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 745-754
-
-
Colin, C.1
Voutsinos-Porche, B.2
Nanni, I.3
Fina, F.4
Metellus, P.5
Intagliata, D.6
-
91
-
-
84867405330
-
PH regulators in invadosomal functioning: proton delivery for matrix tasting
-
Brisson L., Reshkin S.J., Goré J., Roger S. PH regulators in invadosomal functioning: proton delivery for matrix tasting. Eur. J. Cell Biol. 2012, 91:847-860.
-
(2012)
Eur. J. Cell Biol.
, vol.91
, pp. 847-860
-
-
Brisson, L.1
Reshkin, S.J.2
Goré, J.3
Roger, S.4
-
92
-
-
0034486945
-
Imaging proteolysis by living human breast cancer cells
-
Sameni M., Moin K., Sloane B.F. Imaging proteolysis by living human breast cancer cells. Neoplasia 2001, 2:496-504.
-
(2001)
Neoplasia
, vol.2
, pp. 496-504
-
-
Sameni, M.1
Moin, K.2
Sloane, B.F.3
-
93
-
-
84901798130
-
Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways
-
Zhang L., Wang H., Xu J., Zhu J., Ding K. Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways. Toxicol. Lett. 2014, 228:248-259.
-
(2014)
Toxicol. Lett.
, vol.228
, pp. 248-259
-
-
Zhang, L.1
Wang, H.2
Xu, J.3
Zhu, J.4
Ding, K.5
-
94
-
-
33750723597
-
Cystatins in cancer
-
Nova Sciences, New York, E. Žerovnik, N. Kopitar-Jerala, V. Uversky (Eds.)
-
Kos J., Lah T.T. Cystatins in cancer. Human Stefins and Cystatins 2006, 153-165. Nova Sciences, New York. E. Žerovnik, N. Kopitar-Jerala, V. Uversky (Eds.).
-
(2006)
Human Stefins and Cystatins
, pp. 153-165
-
-
Kos, J.1
Lah, T.T.2
-
95
-
-
68549098771
-
Cysteine cathepsins and cystatins as cancer biomarkers
-
Springer Science+Business Media, New York, D. Edwards, G. Hoyer-Hansen, F. Blasi, B.F. Sloane (Eds.)
-
Lah T.T., Obermajer N., Duran Alonso M.B., Kos J. Cysteine cathepsins and cystatins as cancer biomarkers. Cancer Degrad. 2008, 575-613. Springer Science+Business Media, New York. D. Edwards, G. Hoyer-Hansen, F. Blasi, B.F. Sloane (Eds.).
-
(2008)
Cancer Degrad.
, pp. 575-613
-
-
Lah, T.T.1
Obermajer, N.2
Duran Alonso, M.B.3
Kos, J.4
-
97
-
-
80051504987
-
Identification of a myeloid-derived suppressor cell cystatin-like protein that inhibits metastasis
-
Boutté A.M., Friedman D.B., Bogyo M.S., Min Y., Yang L., Lin P.C. Identification of a myeloid-derived suppressor cell cystatin-like protein that inhibits metastasis. FASEB J. 2011, 25:2626-2637.
-
(2011)
FASEB J.
, vol.25
, pp. 2626-2637
-
-
Boutté, A.M.1
Friedman, D.B.2
Bogyo, M.S.3
Min, Y.4
Yang, L.5
Lin, P.C.6
-
98
-
-
47049095033
-
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
-
Vasiljeva O., Korovin M., Gajda M., Brodoefel H., Bojic L., Krüger A., et al. Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice. Oncogene 2008, 27:4191-4199.
-
(2008)
Oncogene
, vol.27
, pp. 4191-4199
-
-
Vasiljeva, O.1
Korovin, M.2
Gajda, M.3
Brodoefel, H.4
Bojic, L.5
Krüger, A.6
-
99
-
-
77249161680
-
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
-
Sevenich L., Schurigt U., Sachse K., Gajda M., Werner F., Müller S., et al. Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:2497-2502.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 2497-2502
-
-
Sevenich, L.1
Schurigt, U.2
Sachse, K.3
Gajda, M.4
Werner, F.5
Müller, S.6
-
100
-
-
0029310512
-
Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution
-
Brömme D., Okamoto K. Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution. Biol. Chem. 1995, 376:379-384.
-
(1995)
Biol. Chem.
, vol.376
, pp. 379-384
-
-
Brömme, D.1
Okamoto, K.2
-
101
-
-
3242812655
-
Cathepsin K is the principal protease in giant cell tumor of bone
-
Lindeman J.H.N., Hanemaaijer R., Mulder A., Dijkstra P.D.S., Szuhai K., Brömme D., et al. Cathepsin K is the principal protease in giant cell tumor of bone. Am. J. Pathol. 2004, 165:593-600.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 593-600
-
-
Lindeman, J.H.N.1
Hanemaaijer, R.2
Mulder, A.3
Dijkstra, P.D.S.4
Szuhai, K.5
Brömme, D.6
-
102
-
-
38349023103
-
Cathepsins and osteosarcoma: expression analysis identifies cathepsin K as an indicator of metastasis
-
Husmann K., Muff R., Bolander M.E., Sarkar G., Born W., Fuchs B. Cathepsins and osteosarcoma: expression analysis identifies cathepsin K as an indicator of metastasis. Mol. Carcinog. 2008, 73:66-73.
-
(2008)
Mol. Carcinog.
, vol.73
, pp. 66-73
-
-
Husmann, K.1
Muff, R.2
Bolander, M.E.3
Sarkar, G.4
Born, W.5
Fuchs, B.6
-
103
-
-
0035130668
-
Cysteine proteinases in chondrosarcomas
-
Söderström M., Ekfors T., Böhling T., Aho A., Aro H.T., Vuorio E. Cysteine proteinases in chondrosarcomas. Matrix Biol. 2001, 19:717-725.
-
(2001)
Matrix Biol.
, vol.19
, pp. 717-725
-
-
Söderström, M.1
Ekfors, T.2
Böhling, T.3
Aho, A.4
Aro, H.T.5
Vuorio, E.6
-
104
-
-
84855359368
-
Cathepsin K expression in the spectrum of perivascular epithelioid cell (PEC) lesions of the kidney
-
Martignoni G., Bonetti F., Chilosi M., Brunelli M., Segala D., Amin M.B., et al. Cathepsin K expression in the spectrum of perivascular epithelioid cell (PEC) lesions of the kidney. Mod. Pathol. 2012, 25:100-111.
-
(2012)
Mod. Pathol.
, vol.25
, pp. 100-111
-
-
Martignoni, G.1
Bonetti, F.2
Chilosi, M.3
Brunelli, M.4
Segala, D.5
Amin, M.B.6
-
105
-
-
84874195401
-
Cathepsin K expression in a wide spectrum of perivascular epithelioid cell neoplasms (PEComas): a clinicopathological study emphasizing extrarenal PEComas
-
Rao Q., Cheng L., Xia Q.-Y., Liu B., Li L., Shi Q.-L., et al. Cathepsin K expression in a wide spectrum of perivascular epithelioid cell neoplasms (PEComas): a clinicopathological study emphasizing extrarenal PEComas. Histopathology 2013, 62:642-650.
-
(2013)
Histopathology
, vol.62
, pp. 642-650
-
-
Rao, Q.1
Cheng, L.2
Xia, Q.-Y.3
Liu, B.4
Li, L.5
Shi, Q.-L.6
-
106
-
-
80053563153
-
Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions
-
Martignoni G., Gobbo S., Camparo P., Brunelli M., Munari E., Segala D., et al. Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions. Mod. Pathol. 2011, 24:1313-1319.
-
(2011)
Mod. Pathol.
, vol.24
, pp. 1313-1319
-
-
Martignoni, G.1
Gobbo, S.2
Camparo, P.3
Brunelli, M.4
Munari, E.5
Segala, D.6
-
107
-
-
84875063007
-
A broad survey of cathepsin K immunoreactivity in human neoplasms
-
Zheng G., Martignoni G., Antonescu C., Montgomery E., Eberhart C., Netto G., et al. A broad survey of cathepsin K immunoreactivity in human neoplasms. Am. J. Clin. Pathol. 2013, 139:151-159.
-
(2013)
Am. J. Clin. Pathol.
, vol.139
, pp. 151-159
-
-
Zheng, G.1
Martignoni, G.2
Antonescu, C.3
Montgomery, E.4
Eberhart, C.5
Netto, G.6
-
108
-
-
77957935854
-
A distinctive subset of PEComas harbors TFE3 gene fusions
-
Argani P., Aulmann S., Illei P.B., Netto G.J., Ro J., Cho H.Y., et al. A distinctive subset of PEComas harbors TFE3 gene fusions. Am. J. Surg. Pathol. 2010, 34:1395-1406.
-
(2010)
Am. J. Surg. Pathol.
, vol.34
, pp. 1395-1406
-
-
Argani, P.1
Aulmann, S.2
Illei, P.B.3
Netto, G.J.4
Ro, J.5
Cho, H.Y.6
-
109
-
-
15144356711
-
The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma
-
Littlewood-Evans A.J., Bilbe G., Bowler W.B., Farley D., Wlodarski B., Kokubo T., et al. The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma. Cancer Res. 1997, 57:5386-5390.
-
(1997)
Cancer Res.
, vol.57
, pp. 5386-5390
-
-
Littlewood-Evans, A.J.1
Bilbe, G.2
Bowler, W.B.3
Farley, D.4
Wlodarski, B.5
Kokubo, T.6
-
110
-
-
0034470303
-
Cathepsin K expression in human lung
-
Bühling F., Waldburg N., Gerber A., Häckel C., Krüger S., Reinhold D., et al. Cathepsin K expression in human lung. Adv. Exp. Med. Biol. 2000, 477:281-286.
-
(2000)
Adv. Exp. Med. Biol.
, vol.477
, pp. 281-286
-
-
Bühling, F.1
Waldburg, N.2
Gerber, A.3
Häckel, C.4
Krüger, S.5
Reinhold, D.6
-
111
-
-
0037302046
-
Cathepsin K mRNA and protein expression in prostate cancer progression
-
Brubaker K.D., Vessella R.L., True L.D., Thomas R., Corey E. Cathepsin K mRNA and protein expression in prostate cancer progression. J. Bone Miner. Res. 2003, 18:222-230.
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 222-230
-
-
Brubaker, K.D.1
Vessella, R.L.2
True, L.D.3
Thomas, R.4
Corey, E.5
-
112
-
-
35448959223
-
A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden
-
Le Gall C., Bellahcène A., Bonnelye E., Gasser J., Castronovo V., Green J., et al. A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden. Cancer Res. 2007, 67:9894-9902.
-
(2007)
Cancer Res.
, vol.67
, pp. 9894-9902
-
-
Le Gall, C.1
Bellahcène, A.2
Bonnelye, E.3
Gasser, J.4
Castronovo, V.5
Green, J.6
-
113
-
-
53049084066
-
Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progression
-
Kleer C.G., Bloushtain-Qimron N., Chen Y.-H., Carrasco D., Hu M., Kraeft S.-K., et al. Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progression. Hum. Cancer Biol. 2008, 14:5357-5367.
-
(2008)
Hum. Cancer Biol.
, vol.14
, pp. 5357-5367
-
-
Kleer, C.G.1
Bloushtain-Qimron, N.2
Chen, Y.-H.3
Carrasco, D.4
Hu, M.5
Kraeft, S.-K.6
-
114
-
-
38949145299
-
Circulating cathepsin K and cystatin C in patients with cancer related bone disease: clinical and therapeutic implications
-
Tumminello F.M., Flandina C., Crescimanno M., Leto G. Circulating cathepsin K and cystatin C in patients with cancer related bone disease: clinical and therapeutic implications. Biomed. Pharmacother. 2008, 62:130-135.
-
(2008)
Biomed. Pharmacother.
, vol.62
, pp. 130-135
-
-
Tumminello, F.M.1
Flandina, C.2
Crescimanno, M.3
Leto, G.4
-
115
-
-
79960555690
-
Multiplex zymography captures stage-specific activity profiles of cathepsins K. L, and S in human breast, lung, and cervical cancer
-
Chen B., Platt M.O. Multiplex zymography captures stage-specific activity profiles of cathepsins K. L, and S in human breast, lung, and cervical cancer. J. Transl. Med. 2011, 9:109.
-
(2011)
J. Transl. Med.
, vol.9
, pp. 109
-
-
Chen, B.1
Platt, M.O.2
-
116
-
-
84948649855
-
CD44 signaling increases cathepsin K and MT1MMP expression to potentiate breast cancer cell invasion through collagen
-
The Royal Society, London, UK
-
Hill A., McFarlane S., Johnston P.G., Waugh D.J.J. CD44 signaling increases cathepsin K and MT1MMP expression to potentiate breast cancer cell invasion through collagen. Meet. Abstr. Breast Cancer Res. 2008, vol. 10 2008, S18. The Royal Society, London, UK.
-
(2008)
Meet. Abstr. Breast Cancer Res. 2008, vol. 10
, pp. S18
-
-
Hill, A.1
McFarlane, S.2
Johnston, P.G.3
Waugh, D.J.J.4
-
117
-
-
84861337133
-
CD44 enhances invasion of basal-like breast cancer cells by up-regulating serine protease and collagen-degrading enzymatic expression and activity
-
Montgomery N., Hill A., McFarlane S., Neisen J., O'Grady A., Conlon S., et al. CD44 enhances invasion of basal-like breast cancer cells by up-regulating serine protease and collagen-degrading enzymatic expression and activity. Breast Cancer Res. 2012, 14:R84.
-
(2012)
Breast Cancer Res.
, vol.14
, pp. R84
-
-
Montgomery, N.1
Hill, A.2
McFarlane, S.3
Neisen, J.4
O'Grady, A.5
Conlon, S.6
-
118
-
-
33750306612
-
Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
-
Balic M., Lin H., Young L., Hawes D., Giuliano A., McNamara G., et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin. Cancer Res. 2006, 12:5615-5621.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5615-5621
-
-
Balic, M.1
Lin, H.2
Young, L.3
Hawes, D.4
Giuliano, A.5
McNamara, G.6
-
119
-
-
61449117010
-
Simultaneous expression of Cathepsins B and K in pulmonary adenocarcinomas and squamous cell carcinomas predicts poor recurrence-free and overall survival
-
Cordes C., Bartling B., Simm A., Afar D., Lautenschläger C., Hansen G., et al. Simultaneous expression of Cathepsins B and K in pulmonary adenocarcinomas and squamous cell carcinomas predicts poor recurrence-free and overall survival. Lung Cancer 2009, 64:79-85.
-
(2009)
Lung Cancer
, vol.64
, pp. 79-85
-
-
Cordes, C.1
Bartling, B.2
Simm, A.3
Afar, D.4
Lautenschläger, C.5
Hansen, G.6
-
120
-
-
73549112017
-
Serum cathepsin K and cystatin C concentration in patients with advanced non-small-cell lung cancer during chemotherapy
-
Naumnik W., Nikliñska W., Ossoliñska M., Chyczewska E., Maria O., Chyczewska E. Serum cathepsin K and cystatin C concentration in patients with advanced non-small-cell lung cancer during chemotherapy. Folia Histochem. Cytobiol. 2009, 47:207-213.
-
(2009)
Folia Histochem. Cytobiol.
, vol.47
, pp. 207-213
-
-
Naumnik, W.1
Nikliñska, W.2
Ossoliñska, M.3
Chyczewska, E.4
Maria, O.5
Chyczewska, E.6
-
121
-
-
33744502621
-
Cathepsin K is selectively expressed in the stroma of lung adenocarcinoma but not in bronchioloalveolar carcinoma
-
Rapa I., Volante M., Cappia S., Rosas R., Scagliotti G.V., Papotti M. Cathepsin K is selectively expressed in the stroma of lung adenocarcinoma but not in bronchioloalveolar carcinoma. Am. J. Clin. Pathol. 2006, 125:847-854.
-
(2006)
Am. J. Clin. Pathol.
, vol.125
, pp. 847-854
-
-
Rapa, I.1
Volante, M.2
Cappia, S.3
Rosas, R.4
Scagliotti, G.V.5
Papotti, M.6
-
122
-
-
80053640221
-
Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression
-
Wang R., Zhang J., Chen S., Lu M., Luo X., Yao S., et al. Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression. Lung Cancer 2011, 74:188-196.
-
(2011)
Lung Cancer
, vol.74
, pp. 188-196
-
-
Wang, R.1
Zhang, J.2
Chen, S.3
Lu, M.4
Luo, X.5
Yao, S.6
-
123
-
-
84896495007
-
The effect of catalase on migration and invasion of lung cancer cells by regulating the activities of cathepsin S L, and K
-
Tsai J.Y., Lee M.J., Dah-Tsyr Chang M., Huang H. The effect of catalase on migration and invasion of lung cancer cells by regulating the activities of cathepsin S L, and K. Exp. Cell Res 2014, 323:28-40.
-
(2014)
Exp. Cell Res
, vol.323
, pp. 28-40
-
-
Tsai, J.Y.1
Lee, M.J.2
Dah-Tsyr Chang, M.3
Huang, H.4
-
124
-
-
34548162174
-
Cathepsin K in the bone microenvironment: link between obesity and prostate cancer?
-
Podgorski I., Linebaugh B.E., Sloane B.F. Cathepsin K in the bone microenvironment: link between obesity and prostate cancer?. Biochem. Soc. Trans. 2007, 35:701-703.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 701-703
-
-
Podgorski, I.1
Linebaugh, B.E.2
Sloane, B.F.3
-
125
-
-
84884211491
-
Macrophage cathepsin K promotes prostate tumor progression in bone
-
Herroon M.K., Rajagurubandara E., Rudy D.L., Chalasani A., Hardaway A.L., Podgorski I. Macrophage cathepsin K promotes prostate tumor progression in bone. Oncogene 2013, 32:1580-1593.
-
(2013)
Oncogene
, vol.32
, pp. 1580-1593
-
-
Herroon, M.K.1
Rajagurubandara, E.2
Rudy, D.L.3
Chalasani, A.4
Hardaway, A.L.5
Podgorski, I.6
-
127
-
-
49549102043
-
Cathepsin K in melanoma invasion
-
Quintanilla-Dieck M.J., Codriansky K., Keady M., Bhawan J., Rünger T.M. Cathepsin K in melanoma invasion. J. Invest. Dermatol. 2008, 128:2281-2288.
-
(2008)
J. Invest. Dermatol.
, vol.128
, pp. 2281-2288
-
-
Quintanilla-Dieck, M.J.1
Codriansky, K.2
Keady, M.3
Bhawan, J.4
Rünger, T.M.5
-
128
-
-
79751480144
-
Stromal expression of cathepsin K in squamous cell carcinoma
-
Yan X., Takahara M., Xie L., Oda Y., Nakahara T., Uchi H., et al. Stromal expression of cathepsin K in squamous cell carcinoma. J. Eur. Acad. Dermatol. Venereol. 2011, 25:362-365.
-
(2011)
J. Eur. Acad. Dermatol. Venereol.
, vol.25
, pp. 362-365
-
-
Yan, X.1
Takahara, M.2
Xie, L.3
Oda, Y.4
Nakahara, T.5
Uchi, H.6
-
129
-
-
78650679889
-
Cathepsin K-upregulation in fibroblasts promotes matrigel invasive ability of squamous cell carcinoma cells via tumor-derived IL-1a
-
Xie L., Moroi Y., Hayashida S., Tsuji G., Takeuchi S., Shan B. Cathepsin K-upregulation in fibroblasts promotes matrigel invasive ability of squamous cell carcinoma cells via tumor-derived IL-1a. J. Dermatol. Sci. 2011, 61:45-50.
-
(2011)
J. Dermatol. Sci.
, vol.61
, pp. 45-50
-
-
Xie, L.1
Moroi, Y.2
Hayashida, S.3
Tsuji, G.4
Takeuchi, S.5
Shan, B.6
-
130
-
-
84894473092
-
Screening of differentially expressed genes related to esophageal squamous cell carcinoma and functional analysis with DNA microarrays
-
Yuan Y., Xue L., Fan H. Screening of differentially expressed genes related to esophageal squamous cell carcinoma and functional analysis with DNA microarrays. Int. J. Oncol. 2014, 44:1163-1170.
-
(2014)
Int. J. Oncol.
, vol.44
, pp. 1163-1170
-
-
Yuan, Y.1
Xue, L.2
Fan, H.3
-
131
-
-
84881340728
-
Cathepsin K is present in invasive oral tongue squamous cell carcinoma in vivo and in vitro
-
Bitu C.C., Kauppila J.H., Bufalino A., Nurmenniemi S., Teppo S., Keinänen M., et al. Cathepsin K is present in invasive oral tongue squamous cell carcinoma in vivo and in vitro. PLOS ONE 2013, 8:e70925.
-
(2013)
PLOS ONE
, vol.8
, pp. e70925
-
-
Bitu, C.C.1
Kauppila, J.H.2
Bufalino, A.3
Nurmenniemi, S.4
Teppo, S.5
Keinänen, M.6
-
132
-
-
77954400771
-
Expression of syndecan-1 and cathepsins D and K in advanced esophageal squamous cell carcinoma
-
Szumilo J., Burdan F., Zinkiewicz K., Dudka J., Klepacz R., Dabrowski A., et al. Expression of syndecan-1 and cathepsins D and K in advanced esophageal squamous cell carcinoma. Folia Histochem. Cytobiol. 2009, 47:571-578.
-
(2009)
Folia Histochem. Cytobiol.
, vol.47
, pp. 571-578
-
-
Szumilo, J.1
Burdan, F.2
Zinkiewicz, K.3
Dudka, J.4
Klepacz, R.5
Dabrowski, A.6
-
133
-
-
68249127067
-
Cathepsin-K immunoreactivity distinguishes MiTF/TFE family renal translocation carcinomas from other renal carcinomas
-
Martignoni G., Pea M., Gobbo S., Brunelli M., Bonetti F., Segala D., et al. Cathepsin-K immunoreactivity distinguishes MiTF/TFE family renal translocation carcinomas from other renal carcinomas. Mod. Pathol. 2009, 22:1016-1022.
-
(2009)
Mod. Pathol.
, vol.22
, pp. 1016-1022
-
-
Martignoni, G.1
Pea, M.2
Gobbo, S.3
Brunelli, M.4
Bonetti, F.5
Segala, D.6
-
134
-
-
84866143199
-
Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K
-
Ren G., Tian Q., An Y., Feng B., Lu Y., Liang J., et al. Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K. Mol. Cancer 2012, 11:67.
-
(2012)
Mol. Cancer
, vol.11
, pp. 67
-
-
Ren, G.1
Tian, Q.2
An, Y.3
Feng, B.4
Lu, Y.5
Liang, J.6
-
135
-
-
84899519077
-
Cathepsin K in the immunohistochemical diagnosis of melanocytic lesions
-
Rao Q., Wang Y., Xia Q.-Y., Shi S.-S., Shen Q., Tu P., et al. Cathepsin K in the immunohistochemical diagnosis of melanocytic lesions. Int. J. Clin. Exp. Pathol. 2014, 7:1132-1139.
-
(2014)
Int. J. Clin. Exp. Pathol.
, vol.7
, pp. 1132-1139
-
-
Rao, Q.1
Wang, Y.2
Xia, Q.-Y.3
Shi, S.-S.4
Shen, Q.5
Tu, P.6
-
136
-
-
84909619212
-
Expression analysis of all protease genes reveals cathepsin K to be overexpressed in glioblastoma
-
Verbovšek U., Motaln H., Rotter A., Atai N.A., Gruden K., Van Noorden C.J.F., et al. Expression analysis of all protease genes reveals cathepsin K to be overexpressed in glioblastoma. PLOS ONE 2014, 9:e111819.
-
(2014)
PLOS ONE
, vol.9
, pp. e111819
-
-
Verbovšek, U.1
Motaln, H.2
Rotter, A.3
Atai, N.A.4
Gruden, K.5
Van Noorden, C.J.F.6
-
137
-
-
84934768519
-
CD133+ and nestin+ glioma stem-like cells reside around CD31+ arterioles in niches that express SDF-1α. CXCR4, osteopontin and cathepsin K
-
Hira V.V.V., Ploegmakers K.J., Verbovšek U., Roing C.S., Aronica E.M.A., Tigchelaar W., et al. CD133+ and nestin+ glioma stem-like cells reside around CD31+ arterioles in niches that express SDF-1α. CXCR4, osteopontin and cathepsin K. J. Histochem. Cytochem. 2015, 63:481-493.
-
(2015)
J. Histochem. Cytochem.
, vol.63
, pp. 481-493
-
-
Hira, V.V.V.1
Ploegmakers, K.J.2
Verbovšek, U.3
Roing, C.S.4
Aronica, E.M.A.5
Tigchelaar, W.6
-
138
-
-
0030747949
-
Direct osteolysis induced by metastatic murine melanoma cells: role of matrix metalloproteinases
-
Sanchez-Sweatman O.H., Lee J., Orr F.W., Singh G. Direct osteolysis induced by metastatic murine melanoma cells: role of matrix metalloproteinases. Eur. J. Cancer 1997, 33:918-925.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 918-925
-
-
Sanchez-Sweatman, O.H.1
Lee, J.2
Orr, F.W.3
Singh, G.4
-
139
-
-
0035826866
-
Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family
-
Motyckova G., Weilbaecher K.N., Horstmann M., Rieman D.J., Fisher D.Z., Fisher D.E. Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:5798-5803.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 5798-5803
-
-
Motyckova, G.1
Weilbaecher, K.N.2
Horstmann, M.3
Rieman, D.J.4
Fisher, D.Z.5
Fisher, D.E.6
-
140
-
-
50549121134
-
The distribution of secondary growths in cancer of breast
-
Paget S. The distribution of secondary growths in cancer of breast. Lancet 1889, 1:571-573.
-
(1889)
Lancet
, vol.1
, pp. 571-573
-
-
Paget, S.1
-
141
-
-
84899927795
-
Recent advances in bone-targeted therapies of metastatic prostate cancer
-
Deng X., He G., Liu J., Luo F., Peng X., Tang S., et al. Recent advances in bone-targeted therapies of metastatic prostate cancer. Cancer Treat. Rev. 2014, 40:730-738.
-
(2014)
Cancer Treat. Rev.
, vol.40
, pp. 730-738
-
-
Deng, X.1
He, G.2
Liu, J.3
Luo, F.4
Peng, X.5
Tang, S.6
-
142
-
-
84934759146
-
Glioblastoma stem-like cells: approaches for isolation and characterization
-
Molina E.S., Pillat M.M., Moura-Neto V., Lah T.T., Ulrich H. Glioblastoma stem-like cells: approaches for isolation and characterization. J. Cancer Stem Cell Res. 2014, 2:e1007.
-
(2014)
J. Cancer Stem Cell Res.
, vol.2
, pp. e1007
-
-
Molina, E.S.1
Pillat, M.M.2
Moura-Neto, V.3
Lah, T.T.4
Ulrich, H.5
-
143
-
-
84903266278
-
Stem cell dynamics in homeostasis and cancer of the intestine
-
Vermeulen L., Snippert H.J. Stem cell dynamics in homeostasis and cancer of the intestine. Nat. Rev. Cancer 2014, 14:468-480.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 468-480
-
-
Vermeulen, L.1
Snippert, H.J.2
-
144
-
-
79551555038
-
Cancer stem cell niche: the place to be
-
Borovski T., De Sousa E., Melo F., Vermeulen L., Medema J.P. Cancer stem cell niche: the place to be. Cancer Res. 2011, 71:634-639.
-
(2011)
Cancer Res.
, vol.71
, pp. 634-639
-
-
Borovski, T.1
De Sousa, E.2
Melo, F.3
Vermeulen, L.4
Medema, J.P.5
-
145
-
-
3042825286
-
Fidelity of runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease
-
Barnes G.L., Hebert K.E., Kamal M., Javed A., Einhorn T.A., Lian J.B., et al. Fidelity of runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease. Cancer Res. 2004, 64:4506-4513.
-
(2004)
Cancer Res.
, vol.64
, pp. 4506-4513
-
-
Barnes, G.L.1
Hebert, K.E.2
Kamal, M.3
Javed, A.4
Einhorn, T.A.5
Lian, J.B.6
-
146
-
-
44449160795
-
Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis
-
Tomita A., Kasaoka T., Inui T., Toyoshima M., Nishiyama H., Saiki H., et al. Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis. Clin. Exp. Metastasis 2008, 25:437-444.
-
(2008)
Clin. Exp. Metastasis
, vol.25
, pp. 437-444
-
-
Tomita, A.1
Kasaoka, T.2
Inui, T.3
Toyoshima, M.4
Nishiyama, H.5
Saiki, H.6
-
147
-
-
15844397808
-
Proteolytic activity of human osteoclast cathepsin K
-
Bossard M.J., Tomaszek T.A., Thompson S.K., Amegadzie B.Y., Hanning C.R., Jones C., et al. Proteolytic activity of human osteoclast cathepsin K. J. Biol. Chem. 1996, 271:12517-12524.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12517-12524
-
-
Bossard, M.J.1
Tomaszek, T.A.2
Thompson, S.K.3
Amegadzie, B.Y.4
Hanning, C.R.5
Jones, C.6
-
148
-
-
77954564655
-
Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis
-
Chiodoni C., Colombo M.P., Sangaletti S. Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis. Cancer Metastasis Rev. 2010, 29:295-307.
-
(2010)
Cancer Metastasis Rev.
, vol.29
, pp. 295-307
-
-
Chiodoni, C.1
Colombo, M.P.2
Sangaletti, S.3
-
149
-
-
84937521344
-
Inflammation and cancer: till death tears them apart
-
Raposo T.P., Beirão B.C.B., Pang L.Y., Queiroga F.L., Argyle D.J. Inflammation and cancer: till death tears them apart. Vet. J. 2015, 205:161-174.
-
(2015)
Vet. J.
, vol.205
, pp. 161-174
-
-
Raposo, T.P.1
Beirão, B.C.B.2
Pang, L.Y.3
Queiroga, F.L.4
Argyle, D.J.5
-
150
-
-
84890312241
-
Heparin blocks transfer of extracellular vesicles between donor and recipient cells
-
Atai N.A., Balaj L., Van Veen H., Breakefield X.O., Jarzyna P.A., Van Noorden C.J.F., et al. Heparin blocks transfer of extracellular vesicles between donor and recipient cells. J. Neurooncol. 2013, 115:343-351.
-
(2013)
J. Neurooncol.
, vol.115
, pp. 343-351
-
-
Atai, N.A.1
Balaj, L.2
Van Veen, H.3
Breakefield, X.O.4
Jarzyna, P.A.5
Van Noorden, C.J.F.6
-
151
-
-
84921918767
-
Mechanisms of cross-talk between glioma and myeloid cells: how to break a vicious cycle
-
Wurdinger T., Deumelandt K., Van DerVliet H.J., De Gruijl T.D. Mechanisms of cross-talk between glioma and myeloid cells: how to break a vicious cycle. BBA - Rev. Cancer 2014, 1846:1-32.
-
(2014)
BBA - Rev. Cancer
, vol.1846
, pp. 1-32
-
-
Wurdinger, T.1
Deumelandt, K.2
Van DerVliet, H.J.3
De Gruijl, T.D.4
-
152
-
-
84929285231
-
Extracellular vesicles in the biology of brain tumour stem cells - implications for inter-cellular communication, therapy and biomarker development
-
Nakano I., Garnier D., Minata M., Rak J. Extracellular vesicles in the biology of brain tumour stem cells - implications for inter-cellular communication, therapy and biomarker development. Semin. Cell Dev. Biol. 2015, 40:1-10.
-
(2015)
Semin. Cell Dev. Biol.
, vol.40
, pp. 1-10
-
-
Nakano, I.1
Garnier, D.2
Minata, M.3
Rak, J.4
-
153
-
-
84857500944
-
Mesenchymal stem cells and glioma cells form a structural as well as a functional syncytium in vitro
-
Schichor C., Albrecht V., Korte B., Buchner A., Riesenberg R., Mysliwietz J., et al. Mesenchymal stem cells and glioma cells form a structural as well as a functional syncytium in vitro. Exp. Neurol. 2012, 234:208-219.
-
(2012)
Exp. Neurol.
, vol.234
, pp. 208-219
-
-
Schichor, C.1
Albrecht, V.2
Korte, B.3
Buchner, A.4
Riesenberg, R.5
Mysliwietz, J.6
-
154
-
-
77952805220
-
Human mesenchymal stem cells and their use in cell-based therapies
-
Motaln H., Schichor C., Lah T.T. Human mesenchymal stem cells and their use in cell-based therapies. Cancer 2010, 116:2519-2530.
-
(2010)
Cancer
, vol.116
, pp. 2519-2530
-
-
Motaln, H.1
Schichor, C.2
Lah, T.T.3
-
155
-
-
84890834828
-
The duality of stem cells: Double-edged sword in tumor evolution and treatment
-
Springer Science+Business Media, Dordrecht, R.R. Resende, H. Ulrich (Eds.)
-
Tajnšek U., Motaln H., Levicar N., Rotter A., Lah T.T. The duality of stem cells: Double-edged sword in tumor evolution and treatment. Trends in Stem Cell Proliferation and Cancer Research 2013, 391-433. Springer Science+Business Media, Dordrecht. R.R. Resende, H. Ulrich (Eds.).
-
(2013)
Trends in Stem Cell Proliferation and Cancer Research
, pp. 391-433
-
-
Tajnšek, U.1
Motaln, H.2
Levicar, N.3
Rotter, A.4
Lah, T.T.5
-
156
-
-
84948706500
-
Could cancer and infection be adverse effects of mesenchymal stromal cell therapy?
-
Arango-Rodriguez M.L. Could cancer and infection be adverse effects of mesenchymal stromal cell therapy?. World J. Stem Cells 2015, 7:408-417.
-
(2015)
World J. Stem Cells
, vol.7
, pp. 408-417
-
-
Arango-Rodriguez, M.L.1
-
157
-
-
50849136495
-
Regulation of cathepsin K activity by hydrogen peroxide
-
Godat E., Hervé-Grépinet V., Veillard F., Lecaille F., Belghazi M., Brömme D., et al. Regulation of cathepsin K activity by hydrogen peroxide. Biol. Chem. 2008, 389:1123-1126.
-
(2008)
Biol. Chem.
, vol.389
, pp. 1123-1126
-
-
Godat, E.1
Hervé-Grépinet, V.2
Veillard, F.3
Lecaille, F.4
Belghazi, M.5
Brömme, D.6
-
158
-
-
41449113496
-
Extracellular catalase activity protects cysteine cathepsins from inactivation by hydrogen peroxide
-
Hervé-Grépinet V., Veillard F., Godat E., Heuzé-Vourc'h N., Lecaille F., Lalmanach G. Extracellular catalase activity protects cysteine cathepsins from inactivation by hydrogen peroxide. FEBS Lett. 2008, 582:1307-1312.
-
(2008)
FEBS Lett.
, vol.582
, pp. 1307-1312
-
-
Hervé-Grépinet, V.1
Veillard, F.2
Godat, E.3
Heuzé-Vourc'h, N.4
Lecaille, F.5
Lalmanach, G.6
-
159
-
-
15844408670
-
Proteolytic-antiproteolytic balance and its regulation in carcinogenesis
-
Skrzydlewska E., Sulkowska M., Koda M., Sulkowski S. Proteolytic-antiproteolytic balance and its regulation in carcinogenesis. World J. Gastroenterol. 2005, 11:1251-1266.
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 1251-1266
-
-
Skrzydlewska, E.1
Sulkowska, M.2
Koda, M.3
Sulkowski, S.4
-
160
-
-
84867193822
-
Thickened skull, scoliosis and other skeletal findings in Unverricht-Lundborg disease link cystatin B function to bone metabolism
-
Suoranta S., Manninen H., Koskenkorva P., Könönen M., Laitinen R., Lehesjoki A.-E., et al. Thickened skull, scoliosis and other skeletal findings in Unverricht-Lundborg disease link cystatin B function to bone metabolism. Bone 2012, 51:1016-1024.
-
(2012)
Bone
, vol.51
, pp. 1016-1024
-
-
Suoranta, S.1
Manninen, H.2
Koskenkorva, P.3
Könönen, M.4
Laitinen, R.5
Lehesjoki, A.-E.6
-
161
-
-
0027978130
-
Immunohistochemical analysis of cathepsins D, B, and L in human breast cancer
-
Castiglioni T., Merino M.J., Elsner B., Lah T.T., Sloane B.F., Emmert-Buck M.R. Immunohistochemical analysis of cathepsins D, B, and L in human breast cancer. Hum. Pathol. 1994, 25:857-862.
-
(1994)
Hum. Pathol.
, vol.25
, pp. 857-862
-
-
Castiglioni, T.1
Merino, M.J.2
Elsner, B.3
Lah, T.T.4
Sloane, B.F.5
Emmert-Buck, M.R.6
-
162
-
-
0028982065
-
Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer
-
Kos J., Šmid A., Krašovec M., Svetic B., Lenarčič B., Vrhovec I., et al. Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer. Biol. Chem. 1995, 376:401-405.
-
(1995)
Biol. Chem.
, vol.376
, pp. 401-405
-
-
Kos, J.1
Šmid, A.2
Krašovec, M.3
Svetic, B.4
Lenarčič, B.5
Vrhovec, I.6
-
163
-
-
0030000541
-
Cathepsins D, B, and L in malignant human lung tissue
-
Ledakis P., Tester W.T., Rosenberg N., Romero-Fischmann D., Daskal I., Lah T.T. Cathepsins D, B, and L in malignant human lung tissue. Clin. Cancer Res. 1996, 2:561-568.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 561-568
-
-
Ledakis, P.1
Tester, W.T.2
Rosenberg, N.3
Romero-Fischmann, D.4
Daskal, I.5
Lah, T.T.6
-
164
-
-
0032999141
-
Cathepsin B immunohistochemical staining in tumor and endothelial cells is a new prognostic factor for survival in patients with brain tumors
-
Strojnik T., Kos J., Židanik B., Goluh R., Lah T.T. Cathepsin B immunohistochemical staining in tumor and endothelial cells is a new prognostic factor for survival in patients with brain tumors. Clin. Cancer Res. 1999, 5:559-567.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 559-567
-
-
Strojnik, T.1
Kos, J.2
Židanik, B.3
Goluh, R.4
Lah, T.T.5
-
165
-
-
0036947460
-
Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients
-
Levicar N., Kos J., Blejec A., Golouh R., Vrhovec I., Frkovic-Grazio S., et al. Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. Cancer Detect. Prev. 2002, 26:42-49.
-
(2002)
Cancer Detect. Prev.
, vol.26
, pp. 42-49
-
-
Levicar, N.1
Kos, J.2
Blejec, A.3
Golouh, R.4
Vrhovec, I.5
Frkovic-Grazio, S.6
-
166
-
-
26044438493
-
Cathepsin L in glioma progression: comparison with cathepsin B
-
Strojnik T., Kavalar R., Trinkaus M., Lah T.T. Cathepsin L in glioma progression: comparison with cathepsin B. Cancer Detect. Prev. 2005, 29:448-455.
-
(2005)
Cancer Detect. Prev.
, vol.29
, pp. 448-455
-
-
Strojnik, T.1
Kavalar, R.2
Trinkaus, M.3
Lah, T.T.4
-
167
-
-
33745918920
-
Cathepsin S expression: an independent prognostic factor in glioblastoma tumours - a pilot study
-
Flannery T., McQuaid S., McGoohan C., McConnell R.S., McGregor G., Mirakhur M., et al. Cathepsin S expression: an independent prognostic factor in glioblastoma tumours - a pilot study. Int. J. Cancer 2006, 119:854-860.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 854-860
-
-
Flannery, T.1
McQuaid, S.2
McGoohan, C.3
McConnell, R.S.4
McGregor, G.5
Mirakhur, M.6
-
168
-
-
0033802696
-
Comparative localization of cathepsin B protein and activity in colorectal cancer
-
Hazen L.G.M., Bleeker F.E., Lauritzen B., Bahns S., Song J., Jonker A., et al. Comparative localization of cathepsin B protein and activity in colorectal cancer. J. Histochem. Cytochem. 2000, 48:1421-1430.
-
(2000)
J. Histochem. Cytochem.
, vol.48
, pp. 1421-1430
-
-
Hazen, L.G.M.1
Bleeker, F.E.2
Lauritzen, B.3
Bahns, S.4
Song, J.5
Jonker, A.6
-
169
-
-
84899484235
-
Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients
-
Vižin T., Christensen I., Wilhelmsen M., Nielsen H., Kos J. Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients. BMC Cancer 2014, 14:259.
-
(2014)
BMC Cancer
, vol.14
, pp. 259
-
-
Vižin, T.1
Christensen, I.2
Wilhelmsen, M.3
Nielsen, H.4
Kos, J.5
-
170
-
-
67649946172
-
Levels of cathepsins S and H in pleural fluids of inflammatory and neoplastic origin
-
Bunatova K., Obermajer N., Kotyza J., Pesek M., Kos J. Levels of cathepsins S and H in pleural fluids of inflammatory and neoplastic origin. Int. J. Biol. Markers 2009, 24:47-51.
-
(2009)
Int. J. Biol. Markers
, vol.24
, pp. 47-51
-
-
Bunatova, K.1
Obermajer, N.2
Kotyza, J.3
Pesek, M.4
Kos, J.5
-
171
-
-
0034128337
-
Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer
-
Kos J., Werle B., Lah T.T., Brunner N. Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer. Int. J. Biol. Markers 2000, 15:84-89.
-
(2000)
Int. J. Biol. Markers
, vol.15
, pp. 84-89
-
-
Kos, J.1
Werle, B.2
Lah, T.T.3
Brunner, N.4
-
172
-
-
77953523682
-
The balance between extracellular cathepsins and cystatin C is of importance for ovarian cancer
-
Kolwijck E., Kos J., Obermajer N., Span P.N., Thomas C.M.G., Massuger L.F.A.G., et al. The balance between extracellular cathepsins and cystatin C is of importance for ovarian cancer. Eur. J. Clin. Invest. 2010, 40:591-599.
-
(2010)
Eur. J. Clin. Invest.
, vol.40
, pp. 591-599
-
-
Kolwijck, E.1
Kos, J.2
Obermajer, N.3
Span, P.N.4
Thomas, C.M.G.5
Massuger, L.F.A.G.6
-
173
-
-
33748308883
-
Targeting proteases: successes, failures and future prospects
-
Turk B. Targeting proteases: successes, failures and future prospects. Nat. Rev. Drug Discov. 2006, 5:785-799.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 785-799
-
-
Turk, B.1
-
174
-
-
70349293659
-
Inactivation of harmful tumour-associated proteolysis by nanoparticulate system
-
Kos J., Obermajer N., Doljak B., Kocbek P., Kristl J. Inactivation of harmful tumour-associated proteolysis by nanoparticulate system. Int. J. Pharm. 2009, 381:106-112.
-
(2009)
Int. J. Pharm.
, vol.381
, pp. 106-112
-
-
Kos, J.1
Obermajer, N.2
Doljak, B.3
Kocbek, P.4
Kristl, J.5
-
175
-
-
0035037940
-
The expression of cathepsins in osteoclast-like giant cells of an anaplastic thyroid carcinoma with tracheal perforation
-
Gaumann A., Hansen T., Köhler H.H., Kommoss F., Mann W., Maurer J., et al. The expression of cathepsins in osteoclast-like giant cells of an anaplastic thyroid carcinoma with tracheal perforation. Pathol. Res. Pract. 2001, 197:257-262.
-
(2001)
Pathol. Res. Pract.
, vol.197
, pp. 257-262
-
-
Gaumann, A.1
Hansen, T.2
Köhler, H.H.3
Kommoss, F.4
Mann, W.5
Maurer, J.6
-
176
-
-
38649091733
-
High cathepsin K levels in men with differentiated thyroid cancer on suppressive l-thyroxine therapy
-
Mikosch P., Kerschan-Schindl K., Woloszczuk W., Stettner H., Kudlacek S., Kresnik E., et al. High cathepsin K levels in men with differentiated thyroid cancer on suppressive l-thyroxine therapy. Thyroid 2008, 18:27-33.
-
(2008)
Thyroid
, vol.18
, pp. 27-33
-
-
Mikosch, P.1
Kerschan-Schindl, K.2
Woloszczuk, W.3
Stettner, H.4
Kudlacek, S.5
Kresnik, E.6
-
177
-
-
0023752014
-
Effects of proteinase inhibitors leupeptin and E-64 on osteoclastic bone resorption
-
Everts V., Beertsen W., Schroder R. Effects of proteinase inhibitors leupeptin and E-64 on osteoclastic bone resorption. Calcif. Tissue Int. 1988, 43:172-178.
-
(1988)
Calcif. Tissue Int.
, vol.43
, pp. 172-178
-
-
Everts, V.1
Beertsen, W.2
Schroder, R.3
-
178
-
-
0036882393
-
Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design
-
Lecaille F., Kaleta J., Brömme D. Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design. Chem. Rev. 2002, 102:4459-4488.
-
(2002)
Chem. Rev.
, vol.102
, pp. 4459-4488
-
-
Lecaille, F.1
Kaleta, J.2
Brömme, D.3
-
179
-
-
0034041529
-
Cathepsin K and the design of inhibitors of cathepsin K
-
Yamashita D.S., Dodds R.A. Cathepsin K and the design of inhibitors of cathepsin K. Curr. Pharm. Des. 2000, 6:1-24.
-
(2000)
Curr. Pharm. Des.
, vol.6
, pp. 1-24
-
-
Yamashita, D.S.1
Dodds, R.A.2
-
180
-
-
18944365919
-
The role of cathepsins in osteoporosis and arthritis: rationale for the design of new therapeutics
-
Yasuda Y., Kaleta J., Brömme D. The role of cathepsins in osteoporosis and arthritis: rationale for the design of new therapeutics. Adv. Drug Deliv. Rev. 2005, 57:973-993.
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 973-993
-
-
Yasuda, Y.1
Kaleta, J.2
Brömme, D.3
-
181
-
-
33646163936
-
Non-covalent cathepsin K inhibitors for the treatment of osteoporosis
-
Kim T.-S., Tasker A.S. Non-covalent cathepsin K inhibitors for the treatment of osteoporosis. Curr. Top. Med. Chem. 2006, 6:355-360.
-
(2006)
Curr. Top. Med. Chem.
, vol.6
, pp. 355-360
-
-
Kim, T.-S.1
Tasker, A.S.2
-
182
-
-
28144452675
-
Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivity
-
Falgueyret J.-P., Desmarais S., Oballa R., Black W.C., Cromlish W., Khougaz K., et al. Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivity. J. Med. Chem. 2005, 48:7535-7543.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 7535-7543
-
-
Falgueyret, J.-P.1
Desmarais, S.2
Oballa, R.3
Black, W.C.4
Cromlish, W.5
Khougaz, K.6
-
183
-
-
33749664751
-
The consequences of lysosomotropism on the design of selective cathepsin K inhibitors
-
Black W.C., Percival M.D. The consequences of lysosomotropism on the design of selective cathepsin K inhibitors. ChemBioChem 2006, 7:1525-1535.
-
(2006)
ChemBioChem
, vol.7
, pp. 1525-1535
-
-
Black, W.C.1
Percival, M.D.2
-
184
-
-
33144484033
-
Identification of a potent and selective non-basic cathepsin K inhibitor
-
Li C.S., Deschenes D., Desmarais S., Falgueyret J.-P., Gauthier J.Y., Kimmel D.B., et al. Identification of a potent and selective non-basic cathepsin K inhibitor. Bioorg. Med. Chem. Lett. 2006, 16:1985-1989.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 1985-1989
-
-
Li, C.S.1
Deschenes, D.2
Desmarais, S.3
Falgueyret, J.-P.4
Gauthier, J.Y.5
Kimmel, D.B.6
-
185
-
-
37349029510
-
Effect of cathepsin K inhibitor basicity on in vivo off-target
-
Desmarais S., Black W.C., Oballa R., Lamontagne S., Riendeau D., Tawa P., et al. Effect of cathepsin K inhibitor basicity on in vivo off-target. Mol. Pharmacol. 2008, 73:1147-1156.
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 1147-1156
-
-
Desmarais, S.1
Black, W.C.2
Oballa, R.3
Lamontagne, S.4
Riendeau, D.5
Tawa, P.6
-
186
-
-
80053049819
-
Inhibitors of cathepsin K: a patent review (2004-2010)
-
Wijkmans J., Gossen J. Inhibitors of cathepsin K: a patent review (2004-2010). Expert Opin. Ther. Pat. 2011, 21:1611-1629.
-
(2011)
Expert Opin. Ther. Pat.
, vol.21
, pp. 1611-1629
-
-
Wijkmans, J.1
Gossen, J.2
-
188
-
-
84917705814
-
Efficacy of a cathepsin K inhibitor in a preclinical model for prevention and treatment of breast cancer bone metastasis
-
Duong L.T.L.T., Wesolowski G.A., Leung P., Oballa R., Pickarski M. Efficacy of a cathepsin K inhibitor in a preclinical model for prevention and treatment of breast cancer bone metastasis. Mol. Cancer Ther. 2014, 13:2898-2909.
-
(2014)
Mol. Cancer Ther.
, vol.13
, pp. 2898-2909
-
-
Duong, L.T.L.T.1
Wesolowski, G.A.2
Leung, P.3
Oballa, R.4
Pickarski, M.5
-
189
-
-
84930516774
-
Odanacatib: a review of its potential in the management of osteoporosis in postmenopausal women
-
Chapurlat R.D. Odanacatib: a review of its potential in the management of osteoporosis in postmenopausal women. Ther. Adv. Musculoskelet. Dis. 2015, 7:103-109.
-
(2015)
Ther. Adv. Musculoskelet. Dis.
, vol.7
, pp. 103-109
-
-
Chapurlat, R.D.1
-
190
-
-
84948661401
-
Merck announces data from pivotal phase 3 fracture outcomes study for odanacatib, an investigational oral, once-weekly treatment for osteoporosis
-
(accessed 19.02.15)
-
Merck Merck announces data from pivotal phase 3 fracture outcomes study for odanacatib, an investigational oral, once-weekly treatment for osteoporosis. Merck Newsroom Home 2014, http://www.mercknewsroom.com/news-release/research-and-development-news/merck-announces-data-pivotal-phase-3-fracture-outcomes-st (accessed 19.02.15).
-
(2014)
Merck Newsroom Home
-
-
-
191
-
-
84894435615
-
The effect of the cathepsin K inhibitor ONO-5334 on trabecular and cortical bone in postmenopausal osteoporosis: the OCEAN study
-
Engelke K., Nagase S., Fuerst T., Small M., Kuwayama T., Deacon S., et al. The effect of the cathepsin K inhibitor ONO-5334 on trabecular and cortical bone in postmenopausal osteoporosis: the OCEAN study. J. Bone Miner. Res. 2014, 29:629-638.
-
(2014)
J. Bone Miner. Res.
, vol.29
, pp. 629-638
-
-
Engelke, K.1
Nagase, S.2
Fuerst, T.3
Small, M.4
Kuwayama, T.5
Deacon, S.6
-
192
-
-
84948666859
-
-
AdisInsight, Springer (accessed 17.08.15).
-
ONO 5334. AdisInsight, Springer 2015. (accessed 17.08.15). http://adisinsight.springer.com/drugs/800024483.
-
(2015)
-
-
-
193
-
-
79958803353
-
Safety and efficacy of the cathepsin K inhibitor ONO-5334 in postmenopausal osteoporosis: the OCEAN study
-
Eastell R., Nagase S., Ohyama M., Small M., Sawyer J., Boonen S., et al. Safety and efficacy of the cathepsin K inhibitor ONO-5334 in postmenopausal osteoporosis: the OCEAN study. J. Bone Miner. Res. 2011, 26:1303-1312.
-
(2011)
J. Bone Miner. Res.
, vol.26
, pp. 1303-1312
-
-
Eastell, R.1
Nagase, S.2
Ohyama, M.3
Small, M.4
Sawyer, J.5
Boonen, S.6
-
195
-
-
28144433007
-
Design and synthesis of tri-ring P 3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K
-
Palmer J.T., Bryant C., Wang D.X., Davis D.E., Setti E.L., Rydzewski R.M., et al. Design and synthesis of tri-ring P 3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K. J. Med. Chem. 2005, 48:7520-7534.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 7520-7534
-
-
Palmer, J.T.1
Bryant, C.2
Wang, D.X.3
Davis, D.E.4
Setti, E.L.5
Rydzewski, R.M.6
-
197
-
-
79952278967
-
The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial
-
Jensen A.B., Wynne C., Ramirez G., He W., Song Y., Berd Y., et al. The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial. Clin. Breast Cancer 2010, 10:452-458.
-
(2010)
Clin. Breast Cancer
, vol.10
, pp. 452-458
-
-
Jensen, A.B.1
Wynne, C.2
Ramirez, G.3
He, W.4
Song, Y.5
Berd, Y.6
-
198
-
-
84948689241
-
-
AdisInsight, Springer (accessed 17.08.15).
-
Odanacatib. AdisInsight, Springer 2015. (accessed 17.08.15). http://adisinsight.springer.com/drugs/800024552.
-
(2015)
-
-
|