Inhibition of cathepsin L lowers the apoptotic threshold of glioblastoma cells by up-regulating p53 and transcription of caspases 3 and 7

Apoptosis

Volumn 16, Issue 7, 2011, Pages 671-682

  Kenig, Saša ^a,c   Frangež, Robert ^b   Pucer, Anja ^a   Lah, Tamara ^a,b  

^a NATIONAL INSTITUTE OF BIOLOGY   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

Author keywords

Apoptosis; Caspase 3; Caspase 7; Cathepsin L; Glioblastoma; P53

Indexed keywords

CASPASE 3; CASPASE 7; CATHEPSIN L; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; GLIOBLASTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSCRIPTION TERMINATION; UPREGULATION;

APOPTOSIS; CASPASE 3; CASPASE 7; CASPASES; CATHEPSIN L; CELL LINE, TUMOR; CELL NUCLEUS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLIOBLASTOMA; HUMANS; LYSOSOMES; MITOCHONDRIAL MEMBRANES; PERMEABILITY; PROTEIN TRANSPORT; REPRESSOR PROTEINS; RNA, MESSENGER; SUBCELLULAR FRACTIONS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 80051546729     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0600-6     Document Type: Article

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