The expression of cathepsins in osteoclast-like giant cells of an anaplastic thyroid carcinoma with tracheal perforation

Pathology Research and Practice

Volumn 197, Issue 4, 2001, Pages 257-262

  Gaumann, A ^a   Hansen, T ^a   Kohler H H ^a   Kommoss, F ^a   Mann, W ^a   Maurer, J ^a   Kirkpatrick, C J ^a   Kriegsmann, J ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Anaplastic thyroid carcinoma; Cathepsin; Cystatin C; Giant cells

Indexed keywords

CATHEPSIN; CATHEPSIN B; CATHEPSIN K; CD68 ANTIGEN; CYSTATIN C;

ADULT; AIRWAY OBSTRUCTION; ANAPLASTIC CARCINOMA; ARTICLE; BRAIN METASTASIS; BRONCHOSCOPY; CANCER INFILTRATION; CANCER INVASION; CANCER PALLIATIVE THERAPY; CASE REPORT; DYSPHAGIA; DYSPNEA; GIANT CELL; HISTOPATHOLOGY; HOARSENESS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; MALE; MONONUCLEAR CELL; OSTEOCLAST; PERFORATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; THYROID CARCINOMA; THYROIDECTOMY; TRACHEA; TUMOR DIFFERENTIATION; TUMOR LOCALIZATION;

EID: 0035037940     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1078/0344-0338-00044     Document Type: Article

References (16)

1. Anaplastic thyroid carcinoma. A study of 70 cases
2. Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts
3. PG-M1: A new monoclonal antibody directed against a fixative-resistant epitope on the macrophage-restricted form of the CD 68 molecule
4. Anaplastic thyroid carcinoma with osteoclast-like giant cells. A clinicopathologic, immunohistochemical, and ultrastructural study
5. The collagenolytic activity of cathepsin K is unique among mammalian proteases
6. Localization of cathepsins B, D, and L in the rat osteoclast by immunolight and -electron microscopy
7. Cathepsin B and its endogenous inhibitor cystatin C in rheumatoid arthritis synovium
8. Synovial giant cells in rheumatoid arthritis: Expression of cystatin C, but not of cathepsin B
9. Study on cathepsin B activity in human thyroid tumors
10. Anaplastic (sarcomatoid) carcinoma of the thyroid gland
11. Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry
12. Degradation of cartilage matrix components by the cysteine proteinases, cathepsins B and L
13. Thyroid tumor as initial presentation of Hodgkin's disease: A case report including the immunophenotyping characterization
14. Two-step mechanism of inhibition of cathepsin B by cystatin C due to displacement of the proteinase occluding loop
15. Osteoclast like giant cell tumor of the thyroid - A variant undifferentiated carcinoma - A case report