Platelets and physics: How platelets "feel" and respond to their mechanical microenvironment

Blood Reviews

Volumn 29, Issue 6, 2015, Pages 377-386

  Qiu, Yongzhi ^a,b,c   Ciciliano, Jordan ^a,b,c   Myers, David R ^a,b,c   Tran, Reginald ^a,b,c   Lam, Wilbur A ^a,b,c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Binding kinetics; Fibrin(ogen); GPIb; Hydrodynamic forces; Integrin; Mechanosensing; Stiffness; VWF

Indexed keywords

ADENOSINE DIPHOSPHATE; ALPHA INTEGRIN; COLLAGEN; FIBRIN; FIBRINOGEN; GLYCOPROTEIN IB; INTEGRIN ALPHA2B BETA3; MYOSIN ADENOSINE TRIPHOSPHATASE; PROTEIN TYROSINE KINASE; TALIN; THROMBIN; THROMBOXANE A2; UNCLASSIFIED DRUG; VINCULIN; VON WILLEBRAND FACTOR; ADAM PROTEIN; ADAMTS13 PROTEIN, HUMAN; ADHESION RECEPTOR; FIBRINOGEN RECEPTOR; PROTEIN BINDING; THROMBIN RECEPTOR;

BINDING KINETICS; BLOOD CLOTTING; CONFORMATIONAL TRANSITION; CYTOSKELETON; EXTRACELLULAR MATRIX; FIBRIN FORMATION; FIBRIN POLYMERIZATION; HEMOSTASIS; HUMAN; HYDRODYNAMICS; MECHANOTRANSDUCTION; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN UNFOLDING; REVIEW; SHEAR RATE; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROTEIN CONFORMATION; PROTEIN FOLDING; ULTRASTRUCTURE;

ADAM PROTEINS; BLOOD PLATELETS; CYTOSKELETON; FIBRIN; FIBRINOGEN; GENE EXPRESSION REGULATION; HUMANS; MECHANOTRANSDUCTION, CELLULAR; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; VON WILLEBRAND FACTOR;

EID: 84948070261     PISSN: 0268960X     EISSN: 15321681     Source Type: Journal    
DOI: 10.1016/j.blre.2015.05.002     Document Type: Article

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