-
1
-
-
0036851876
-
Platelets in atherothrombosis
-
Ruggeri ZM. Platelets in atherothrombosis. Nat Med. 2002;8:1227-1234.
-
(2002)
Nat Med
, vol.8
, pp. 1227-1234
-
-
Ruggeri, Z.M.1
-
2
-
-
0030742897
-
Platelet receptors for collagen
-
Moroi M, Jung SM. Platelet receptors for collagen. Thromb Haemost. 1997;78:439-444.
-
(1997)
Thromb Haemost
, vol.78
, pp. 439-444
-
-
Moroi, M.1
Jung, S.M.2
-
3
-
-
0035045208
-
Platelet adhesion enhances glycoprotein VI-dependent procoagulant response
-
Siljander P, Farndale RW, Feijge MAH, Comfurius P, Kos S, Bevers EM, Heemskerk JWM. Platelet adhesion enhances glycoprotein VI-dependent procoagulant response. Arterioscler Thromb Vasc Biol. 2001;21:618-627.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 618-627
-
-
Siljander, P.1
Farndale, R.W.2
Feijge, M.A.H.3
Comfurius, P.4
Kos, S.5
Bevers, E.M.6
Heemskerk, J.W.M.7
-
4
-
-
0032879824
-
Influence of fibrillar collagen structure on the mechanisms of platelet thrombus formation under flow
-
Savage B, Ginsberg MH, Ruggeri ZM. Influence of fibrillar collagen structure on the mechanisms of platelet thrombus formation under flow. Blood. 1999;94:2704-2715.
-
(1999)
Blood
, vol.94
, pp. 2704-2715
-
-
Savage, B.1
Ginsberg, M.H.2
Ruggeri, Z.M.3
-
5
-
-
17744381152
-
Glycoprotein VI but not α2β1 integrin is essential for platelet interaction with collagen
-
Nieswandt B, Brakebusch C, Bergmeier W, Schulte V, Bouvard D, Mohtari-Nejad R, Lindhout T, Heemskerk JWM, Zirngibl H, Fässler R. Glycoprotein VI but not α2β1 integrin is essential for platelet interaction with collagen. EMBO J. 2001;20:2120-2130.
-
(2001)
EMBO J
, vol.20
, pp. 2120-2130
-
-
Nieswandt, B.1
Brakebusch, C.2
Bergmeier, W.3
Schulte, V.4
Bouvard, D.5
Mohtari-Nejad, R.6
Lindhout, T.7
Heemskerk, J.W.M.8
Zirngibl, H.9
Fässler, R.10
-
6
-
-
0032523064
-
Integrin signaling, the platelet paradigm
-
Shattil SJ, Kashiwagi H, Pampori N. Integrin signaling, the platelet paradigm. Blood. 1998;91:2645-2657.
-
(1998)
Blood
, vol.91
, pp. 2645-2657
-
-
Shattil, S.J.1
Kashiwagi, H.2
Pampori, N.3
-
7
-
-
0037039439
-
Functional self-association of von Willebrand factor during platelet adhesion under flow
-
Savage B, Sixma JJ, Ruggeri ZM. Functional self-association of von Willebrand factor during platelet adhesion under flow. Proc Natl Acad Sci U S A. 2002;99:425-430.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 425-430
-
-
Savage, B.1
Sixma, J.J.2
Ruggeri, Z.M.3
-
8
-
-
0031471678
-
Integrin signaling in vascular biology
-
Shattil SJ, Ginsberg MH. Integrin signaling in vascular biology. J Clin Invest. 1997;100:1-5.
-
(1997)
J Clin Invest
, vol.100
, pp. 1-5
-
-
Shattil, S.J.1
Ginsberg, M.H.2
-
9
-
-
0037023778
-
Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of adhesive function of integrin αIIbβ3
-
Kasirer-Friede A, Ware J, Leng L, Marchese P, Ruggeri ZM, Shattil SJ. Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of adhesive function of integrin αIIbβ3. J Biol Chem. 2002;277:11949-11956.
-
(2002)
J Biol Chem
, vol.277
, pp. 11949-11956
-
-
Kasirer-Friede, A.1
Ware, J.2
Leng, L.3
Marchese, P.4
Ruggeri, Z.M.5
Shattil, S.J.6
-
10
-
-
0344200064
-
Role of intracellular signaling events in ADP-induced platelet aggregation
-
Daniel JL, Dangelmaier C, Jin JG, Kim YB, Kunapuli SP. Role of intracellular signaling events in ADP-induced platelet aggregation. Thromb Haemost. 1999;82:1322-1326.
-
(1999)
Thromb Haemost
, vol.82
, pp. 1322-1326
-
-
Daniel, J.L.1
Dangelmaier, C.2
Jin, J.G.3
Kim, Y.B.4
Kunapuli, S.P.5
-
12
-
-
0042388099
-
Platelet α2β1 integrin activation: Contribution of ligand internalization and the α2-cytoplasmic domain
-
Wang Z, Leisner TM, Parise LV. Platelet α2β1 integrin activation: contribution of ligand internalization and the α2-cytoplasmic domain. Blood. 2003;102:1307-1315.
-
(2003)
Blood
, vol.102
, pp. 1307-1315
-
-
Wang, Z.1
Leisner, T.M.2
Parise, L.V.3
-
14
-
-
0037031906
-
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
-
Takagi J, Petre BM, Walz T, Springer TA. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell. 2002;110:599-511.
-
(2002)
Cell
, vol.110
, pp. 599-511
-
-
Takagi, J.1
Petre, B.M.2
Walz, T.3
Springer, T.A.4
-
15
-
-
0037047083
-
Involvement of glycoprotein VI in platelet thrombus formation on both collagen and von Willebrand factor surfaces under flow conditions
-
Goto S, Tamura N, Handa S, Arai M, Kodama K, Takayama H. Involvement of glycoprotein VI in platelet thrombus formation on both collagen and von Willebrand factor surfaces under flow conditions. Circulation. 2002;106:266-272.
-
(2002)
Circulation
, vol.106
, pp. 266-272
-
-
Goto, S.1
Tamura, N.2
Handa, S.3
Arai, M.4
Kodama, K.5
Takayama, H.6
-
16
-
-
0038494921
-
Platelet collagen interaction: Is GPVI the central receptor?
-
Nieswandt B, Watson SP. Platelet collagen interaction: is GPVI the central receptor? Blood. 2003;102:449-461.
-
(2003)
Blood
, vol.102
, pp. 449-461
-
-
Nieswandt, B.1
Watson, S.P.2
-
17
-
-
0842328842
-
Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood
-
Siljander PRM, Munnix ICA, Smethurst PA, Deckmyn H, Lindhout T, Ouwehand WH, Farndale RW, Heemskerk JWM. Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood. Blood. 2004;103:1333-1341.
-
(2004)
Blood
, vol.103
, pp. 1333-1341
-
-
Siljander, P.R.M.1
Munnix, I.C.A.2
Smethurst, P.A.3
Deckmyn, H.4
Lindhout, T.5
Ouwehand, W.H.6
Farndale, R.W.7
Heemskerk, J.W.M.8
-
18
-
-
0037240588
-
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo
-
Massberg S, Gawaz M, Grüner S, Schulte V, Konrad I, Zohlhöfer D, Heinzmann U, Nieswandt B. A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo. J Exp Med. 2003;197:41-49.
-
(2003)
J Exp Med
, vol.197
, pp. 41-49
-
-
Massberg, S.1
Gawaz, M.2
Grüner, S.3
Schulte, V.4
Konrad, I.5
Zohlhöfer, D.6
Heinzmann, U.7
Nieswandt, B.8
-
19
-
-
0037169552
-
The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in receptor density-dependent fashion
-
Chen H, Locke D, Liu Y, Liu C, Kahn ML. The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in receptor density-dependent fashion. J Biol Chem. 2002;277:3011-3019.
-
(2002)
J Biol Chem
, vol.277
, pp. 3011-3019
-
-
Chen, H.1
Locke, D.2
Liu, Y.3
Liu, C.4
Kahn, M.L.5
-
20
-
-
0141923911
-
GPVI levels in platelets: Relationship to platelet function at high shear
-
Best D, Senis YA, Jarvis GE, Eagleton HJ, Roberts DJ, Saito T, Jung SM, Moroi M, Harrison P, Green FR, Watson SP. GPVI levels in platelets: relationship to platelet function at high shear. Blood. 2003;102:2811-2818.
-
(2003)
Blood
, vol.102
, pp. 2811-2818
-
-
Best, D.1
Senis, Y.A.2
Jarvis, G.E.3
Eagleton, H.J.4
Roberts, D.J.5
Saito, T.6
Jung, S.M.7
Moroi, M.8
Harrison, P.9
Green, F.R.10
Watson, S.P.11
-
21
-
-
0042442163
-
The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion
-
Kato K, Kanaji T, Russell S, Kunicki TJ, Furihata K, Kanaji S, Marchese P, Reininger A, Ruggeri ZM, Ware J. The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion. Blood. 2003;102:170-1707.
-
(2003)
Blood
, vol.102
, pp. 170-1707
-
-
Kato, K.1
Kanaji, T.2
Russell, S.3
Kunicki, T.J.4
Furihata, K.5
Kanaji, S.6
Marchese, P.7
Reininger, A.8
Ruggeri, Z.M.9
Ware, J.10
-
22
-
-
0037389469
-
Complementary roles of glycoprotein VI and α2β1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo
-
Kuijpers MJE, Schulte V, Bergmeier W, Lindhout T, Brakebusch C, Offermanns S, Fässler R, Heemskerk JWM, Nieswandt B. Complementary roles of glycoprotein VI and α2β1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo. FASEB J. 2003;17:685-687.
-
(2003)
FASEB J
, vol.17
, pp. 685-687
-
-
Kuijpers, M.J.E.1
Schulte, V.2
Bergmeier, W.3
Lindhout, T.4
Brakebusch, C.5
Offermanns, S.6
Fässler, R.7
Heemskerk, J.W.M.8
Nieswandt, B.9
-
23
-
-
0038112077
-
Reciprocal signaling by integrin and nonintegrin receptors during collagen activation of platelets
-
Chen H, Kahn ML. Reciprocal signaling by integrin and nonintegrin receptors during collagen activation of platelets. Mol Cell Biol. 2003;23:4764-4777.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4764-4777
-
-
Chen, H.1
Kahn, M.L.2
-
24
-
-
0041737534
-
Murine GPVI stimulates weak integrin activation in PLCγ2 -/- platelets
-
Suzuki-Inoue K, Inoue O, Frampton J, Watson SP. Murine GPVI stimulates weak integrin activation in PLCγ2 -/- platelets. Blood. 2003;102:1367-1373.
-
(2003)
Blood
, vol.102
, pp. 1367-1373
-
-
Suzuki-Inoue, K.1
Inoue, O.2
Frampton, J.3
Watson, S.P.4
-
25
-
-
0035760304
-
1 is required to inhibit platelet aggregation in whole blood under flow
-
1 is required to inhibit platelet aggregation in whole blood under flow. Blood. 2001;98:3340-3345.
-
(2001)
Blood
, vol.98
, pp. 3340-3345
-
-
Turner, N.A.1
Moake, J.L.2
McIntire, L.V.3
-
26
-
-
0036121597
-
12 in platelet adhesion and thrombus formation in flowing blood
-
12 in platelet adhesion and thrombus formation in flowing blood. Arterioscler Thromb Vasc Biol. 2002;22:686-691.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 686-691
-
-
Remijn, J.A.1
Wu, Y.P.2
Heninga, E.H.3
Ijsseldijk, M.J.W.4
Van Willigen, G.5
De Groot, P.G.6
Sixma, J.J.7
Nurden, A.T.8
Nurden, P.9
-
28
-
-
0033615963
-
Analysis of the roles of 14-3-3 in platelet glycoprotein Ib-IX-mediated activation of integrin αIIbβ3 using a reconstituted mammalian cell expression model
-
Gu MY, Xi XD, Englund GD, Berndt MC, Du XP. Analysis of the roles of 14-3-3 in platelet glycoprotein Ib-IX-mediated activation of integrin αIIbβ3 using a reconstituted mammalian cell expression model. J Cell Biol. 1999;147:1085-1096.
-
(1999)
J Cell Biol
, vol.147
, pp. 1085-1096
-
-
Gu, M.Y.1
Xi, X.D.2
Englund, G.D.3
Berndt, M.C.4
Du, X.P.5
-
29
-
-
0034731480
-
Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin αIIbβ3
-
Yap CL, Hughan SC, Cranmer SL, Nesbitt WS, Rooney MM, Giuliano S, Kulkarni S, Dopheide SM, Yuan YP, Salem HH, Jackson SP. Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin αIIbβ3. J Biol Chem. 2000;275:41377-41388.
-
(2000)
J Biol Chem
, vol.275
, pp. 41377-41388
-
-
Yap, C.L.1
Hughan, S.C.2
Cranmer, S.L.3
Nesbitt, W.S.4
Rooney, M.M.5
Giuliano, S.6
Kulkarni, S.7
Dopheide, S.M.8
Yuan, Y.P.9
Salem, H.H.10
Jackson, S.P.11
-
30
-
-
1542755135
-
Human platelet glycoprotein VI function is antagonised by monoclonal antibody-derived Fab fragments
-
Lecut C, Feeney LA, Kingsbury G, Hopkins J, Lanza F, Cachet C, Villeval JL, Jandrot-Perrus M. Human platelet glycoprotein VI function is antagonised by monoclonal antibody-derived Fab fragments. J Thromb Haemost. 2003;1:2653-2662.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 2653-2662
-
-
Lecut, C.1
Feeney, L.A.2
Kingsbury, G.3
Hopkins, J.4
Lanza, F.5
Cachet, C.6
Villeval, J.L.7
Jandrot-Perrus, M.8
-
31
-
-
0030845821
-
Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine and procoagulant activity of adherent platelets
-
Heemskerk JWM, Vuist WMJ, Feijge MAH, Reutelingsperger CPM, Lindhout T. Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine and procoagulant activity of adherent platelets. Blood. 1997;90:2615-2625.
-
(1997)
Blood
, vol.90
, pp. 2615-2625
-
-
Heemskerk, J.W.M.1
Vuist, W.M.J.2
Feijge, M.A.H.3
Reutelingsperger, C.P.M.4
Lindhout, T.5
-
32
-
-
3142629912
-
Monoclonal antibody IAC-1 is specific for activated α2β1 and binds to amino acid 199-201 of the integrin α2 I-domain
-
in press
-
Schoolmeester A, Vanhoorelbeke K, Depraetere H, Feys HB, Heemskerk JWM, Hoylaerts M, Deckmyn H. Monoclonal antibody IAC-1 is specific for activated α2β1 and binds to amino acid 199-201 of the integrin α2 I-domain. Blood 2004;in press.
-
(2004)
Blood
-
-
Schoolmeester, A.1
Vanhoorelbeke, K.2
Depraetere, H.3
Feys, H.B.4
Heemskerk, J.W.M.5
Hoylaerts, M.6
Deckmyn, H.7
-
33
-
-
0028306890
-
Determinants of specificity of a baculovirus-expressed antibody Fab fragment that binds selectively to activated form of integrin αIIbβ3
-
Abrams C, Deng YJ, Steiner B, O'Toole T, Shattil SJ. Determinants of specificity of a baculovirus-expressed antibody Fab fragment that binds selectively to activated form of integrin αIIbβ3. J Biol Chem. 1994;269:18781-18788.
-
(1994)
J Biol Chem
, vol.269
, pp. 18781-18788
-
-
Abrams, C.1
Deng, Y.J.2
Steiner, B.3
O'Toole, T.4
Shattil, S.J.5
-
34
-
-
0035437196
-
Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibα reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibα
-
Cauwenberghs N, Vanhoorelbeke K, Vauterin S, Westra DF, Romo G, Huizinga EG, Lopez JA, Berndt MC, Harsfalvi J, Deckmyn H. Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibα reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibα. Blood. 2001;98:652-660.
-
(2001)
Blood
, vol.98
, pp. 652-660
-
-
Cauwenberghs, N.1
Vanhoorelbeke, K.2
Vauterin, S.3
Westra, D.F.4
Romo, G.5
Huizinga, E.G.6
Lopez, J.A.7
Berndt, M.C.8
Harsfalvi, J.9
Deckmyn, H.10
-
35
-
-
0037416053
-
Integrin α2β1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCγ2
-
Inoue O, Suzuki-Inoue K, Dean WL, Frampton J, Watson SP. Integrin α2β1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCγ2. J Cell Biol. 160;769-780.
-
J Cell Biol
, vol.160
, pp. 769-780
-
-
Inoue, O.1
Suzuki-Inoue, K.2
Dean, W.L.3
Frampton, J.4
Watson, S.P.5
|