메뉴 건너뛰기




Volumn 2015, Issue , 2015, Pages

Evaluation of microRNAs regulating anoikis pathways and its therapeutic potential

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; RNA;

EID: 84947583554     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/716816     Document Type: Review
Times cited : (28)

References (90)
  • 1
    • 0035960736 scopus 로고    scopus 로고
    • An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin-and myosin-dependent mechanism
    • J. Rosenblatt, M. C. Raf, and L. P. Cramer, "An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin-and myosin-dependent mechanism," Current Biology, vol. 11, no. 23, pp. 1847-1857, 2001.
    • (2001) Current Biology , vol.11 , Issue.23 , pp. 1847-1857
    • Rosenblatt, J.1    Raf, M.C.2    Cramer, L.P.3
  • 2
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • S. M. Frisch and H. Francis, "Disruption of epithelial cell-matrix interactions induces apoptosis," Journal of Cell Biology, vol. 124, no. 4, pp. 619-626, 1994.
    • (1994) Journal of Cell Biology , vol.124 , Issue.4 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 3
    • 84906936187 scopus 로고    scopus 로고
    • Cancer cell survival during detachment from the ECM: Multiple barriers to tumour progression
    • C. L. Buchheit, K. J. Weigel, and Z. T. Schafer, "Cancer cell survival during detachment from the ECM: multiple barriers to tumour progression," Nature Reviews Cancer, vol. 14, no. 9, pp. 632-641, 2014.
    • (2014) Nature Reviews Cancer , vol.14 , Issue.9 , pp. 632-641
    • Buchheit, C.L.1    Weigel, K.J.2    Schafer, Z.T.3
  • 5
    • 0033588007 scopus 로고    scopus 로고
    • A role for reactive oxygen species in endothelial cell anoikis
    • A. E. Li, H. Ito, I. I. Rovira et al., "A role for reactive oxygen species in endothelial cell anoikis," Circulation Research, vol. 85, no. 4, pp. 304-310, 1999.
    • (1999) Circulation Research , vol.85 , Issue.4 , pp. 304-310
    • Li, A.E.1    Ito, H.2    Rovira, I.I.3
  • 6
    • 80054031545 scopus 로고    scopus 로고
    • Overcoming anoikis-pathways to anchorageindependent growth in cancer
    • M. C. Guadamillas, A. Cerezo, and M. A. del Pozo, "Overcoming anoikis-pathways to anchorageindependent growth in cancer," Journal of Cell Science, vol. 124, no. 19, pp. 3189-3197, 2011.
    • (2011) Journal of Cell Science , vol.124 , Issue.19 , pp. 3189-3197
    • Guadamillas, M.C.1    Cerezo, A.2    Del Pozo, M.A.3
  • 7
    • 55949136859 scopus 로고    scopus 로고
    • Anoikis resistance and tumor metastasis
    • C. D. Simpson, K. Anyiwe, and A. D. Schimmer, "Anoikis resistance and tumor metastasis," Cancer Letters, vol. 272, no. 2, pp. 177-185, 2008.
    • (2008) Cancer Letters , vol.272 , Issue.2 , pp. 177-185
    • Simpson, C.D.1    Anyiwe, K.2    Schimmer, A.D.3
  • 8
    • 55949128465 scopus 로고    scopus 로고
    • Anoikis: A necessary death program for anchorage-dependent cells
    • P. Chiarugi and E. Giannoni, "Anoikis: a necessary death program for anchorage-dependent cells," Biochemical Pharmacology, vol. 76, no. 11, pp. 1352-1364, 2008.
    • (2008) Biochemical Pharmacology , vol.76 , Issue.11 , pp. 1352-1364
    • Chiarugi, P.1    Giannoni, E.2
  • 10
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • J. S. Desgrosellier and D. A. Cheresh, "Integrins in cancer: biological implications and therapeutic opportunities," Nature Reviews Cancer, vol. 10, no. 1, pp. 9-22, 2010.
    • (2010) Nature Reviews Cancer , vol.10 , Issue.1 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 11
    • 77957935569 scopus 로고    scopus 로고
    • 1B integrin isoform in caspase-8-dependent integrin-mediated keratinocyte death
    • 1B integrin isoform in caspase-8-dependent integrin-mediated keratinocyte death," Journal of Investigative Dermatology, vol. 130, no. 11, pp. 2569-2577, 2010.
    • (2010) Journal of Investigative Dermatology , vol.130 , Issue.11 , pp. 2569-2577
    • Lotti, R.1    Marconi, A.2    Truzzi, F.3
  • 13
    • 84866736640 scopus 로고    scopus 로고
    • A bigger picture: Classical cadherins and the dynamic actin cytoskeleton
    • A. Ratheesh and A. S. Yap, "A bigger picture: classical cadherins and the dynamic actin cytoskeleton," Nature Reviews Molecular Cell Biology, vol. 13, no. 10, pp. 673-679, 2012.
    • (2012) Nature Reviews Molecular Cell Biology , vol.13 , Issue.10 , pp. 673-679
    • Ratheesh, A.1    Yap, A.S.2
  • 14
    • 84903577507 scopus 로고    scopus 로고
    • E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis
    • M. Lu, S. Marsters, X. Ye, E. Luis, L. Gonzalez, and A. Ashkenazi, "E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis," Molecular Cell, vol. 54, no. 6, pp. 987-998, 2014.
    • (2014) Molecular Cell , vol.54 , Issue.6 , pp. 987-998
    • Lu, M.1    Marsters, S.2    Ye, X.3    Luis, E.4    Gonzalez, L.5    Ashkenazi, A.6
  • 15
    • 0036016923 scopus 로고    scopus 로고
    • Molecular mechanisms of 'detachment-induced apoptosis-Anoikis'
    • J. Grossmann, "Molecular mechanisms of 'detachment-induced apoptosis-Anoikis'," Apoptosis, vol. 7, no. 3, pp. 247-260, 2002.
    • (2002) Apoptosis , vol.7 , Issue.3 , pp. 247-260
    • Grossmann, J.1
  • 16
    • 0037155159 scopus 로고    scopus 로고
    • E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts
    • E. M. Kovacs, R. G. Ali, A. J. McCormack, and A. S. Yap, "E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts," The Journal of Biological Chemistry, vol. 277, no. 8, pp. 6708-6718, 2002.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.8 , pp. 6708-6718
    • Kovacs, E.M.1    Ali, R.G.2    McCormack, A.J.3    Yap, A.S.4
  • 17
    • 77349116653 scopus 로고    scopus 로고
    • E-cadherin protects primary hepatocyte spheroids from cell death by a caspase-independent mechanism
    • J. L. Luebke-Wheeler, G. Nedredal, L. Yee, B. P. Amiot, and S. L. Nyberg, "E-cadherin protects primary hepatocyte spheroids from cell death by a caspase-independent mechanism," Cell Transplantation, vol. 18, no. 12, pp. 1281-1287, 2009.
    • (2009) Cell Transplantation , vol.18 , Issue.12 , pp. 1281-1287
    • Luebke-Wheeler, J.L.1    Nedredal, G.2    Yee, L.3    Amiot, B.P.4    Nyberg, S.L.5
  • 18
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • T. T. Onder, P. B. Gupta, S. A. Mani, J. Yang, E. S. Lander, and R. A. Weinberg, "Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways," Cancer Research, vol. 68, no. 10, pp. 3645-3654, 2008.
    • (2008) Cancer Research , vol.68 , Issue.10 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 19
    • 0035328628 scopus 로고    scopus 로고
    • N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells
    • G. Li, K. Satyamoorthy, and M. Herlyn, "N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells," Cancer Research, vol. 61, no. 9, pp. 3819-3825, 2001.
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3819-3825
    • Li, G.1    Satyamoorthy, K.2    Herlyn, M.3
  • 20
    • 84877043848 scopus 로고    scopus 로고
    • A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation
    • L.-B. Weiswald, S. Richon, G. Massonnet et al., "A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation," British Journal of Cancer, vol. 108, no. 8, pp. 1720-1731, 2013.
    • (2013) British Journal of Cancer , vol.108 , Issue.8 , pp. 1720-1731
    • Weiswald, L.-B.1    Richon, S.2    Massonnet, G.3
  • 21
    • 84906828142 scopus 로고    scopus 로고
    • Identifcation of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells
    • S. K. Hindupur, S. A. Balaji, M. Saxena et al., "Identifcation of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells," Breast Cancer Research, vol. 16, no. 4, article 420, 2014.
    • (2014) Breast Cancer Research , vol.16 , Issue.4
    • Hindupur, S.K.1    Balaji, S.A.2    Saxena, M.3
  • 22
    • 68149166750 scopus 로고    scopus 로고
    • Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness
    • L.-B. Weiswald, S. Richon, P. Validire et al., "Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness," British Journal of Cancer, vol. 101, no. 3, pp. 473-482, 2009.
    • (2009) British Journal of Cancer , vol.101 , Issue.3 , pp. 473-482
    • Weiswald, L.-B.1    Richon, S.2    Validire, P.3
  • 23
    • 84869866890 scopus 로고    scopus 로고
    • MicroRNA and cancer
    • M. D. Jansson and A. H. Lund, "MicroRNA and cancer," Molecular Oncology, vol. 6, no. 6, pp. 590-610, 2012.
    • (2012) Molecular Oncology , vol.6 , Issue.6 , pp. 590-610
    • Jansson, M.D.1    Lund, A.H.2
  • 24
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • L. P. Lim, N. C. Lau, P. Garrett-Engele et al., "Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs," Nature, vol. 433, no. 7027, pp. 769-773, 2005.
    • (2005) Nature , vol.433 , Issue.7027 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3
  • 25
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • A. Krek, D. Grün, M. N. Poy et al., "Combinatorial microRNA target predictions," Nature Genetics, vol. 37, no. 5, pp. 495-500, 2005.
    • (2005) Nature Genetics , vol.37 , Issue.5 , pp. 495-500
    • Krek, A.1    Grün, D.2    Poy, M.N.3
  • 26
    • 84878894582 scopus 로고    scopus 로고
    • MIR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells
    • L. Zhang, X. Wang, and P. Chen, "MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells," BMC Cancer, vol. 13, article 290, 2013.
    • (2013) BMC Cancer , vol.13
    • Zhang, L.1    Wang, X.2    Chen, P.3
  • 28
    • 70349565231 scopus 로고    scopus 로고
    • SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis
    • H. Cheng, P. Liu, Z. C. Wang et al., "SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis," Science Signaling, vol. 2, no. 80, article ra35, 2009.
    • (2009) Science Signaling , vol.2 , Issue.80
    • Cheng, H.1    Liu, P.2    Wang, Z.C.3
  • 29
    • 84874547217 scopus 로고    scopus 로고
    • MicroRNA-204-5p regulates epithelial-to-mesenchymal transition during human posterior capsule opacifcation by targeting SMAD4
    • Y. Wang, W. Li, X. Zang et al., "MicroRNA-204-5p regulates epithelial-to-mesenchymal transition during human posterior capsule opacifcation by targeting SMAD4," Investigative Ophthalmology & Visual Science, vol. 54, no. 1, pp. 323-332, 2013.
    • (2013) Investigative Ophthalmology & Visual Science , vol.54 , Issue.1 , pp. 323-332
    • Wang, Y.1    Li, W.2    Zang, X.3
  • 30
    • 84879602053 scopus 로고    scopus 로고
    • MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin-6-Stat3 pathway
    • X. Yang, L. Liang, X.-F. Zhang et al., "MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin-6-Stat3 pathway," Hepatology, vol. 58, no. 1, pp. 158-170, 2013.
    • (2013) Hepatology , vol.58 , Issue.1 , pp. 158-170
    • Yang, X.1    Liang, L.2    Zhang, X.-F.3
  • 31
    • 84899481668 scopus 로고    scopus 로고
    • MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway
    • X. Yang, X.-F. Zhang, X. Lu et al., "MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway," Hepatology, vol. 59, no. 5, pp. 1874-1885, 2014.
    • (2014) Hepatology , vol.59 , Issue.5 , pp. 1874-1885
    • Yang, X.1    Zhang, X.-F.2    Lu, X.3
  • 32
    • 84922985286 scopus 로고    scopus 로고
    • MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin
    • X. Zhang, S.-L. Cheng, K. Bian et al., "MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin," Oncotarget, vol. 6, no. 4, pp. 2277-2289, 2015.
    • (2015) Oncotarget , vol.6 , Issue.4 , pp. 2277-2289
    • Zhang, X.1    Cheng, S.-L.2    Bian, K.3
  • 33
    • 39849104758 scopus 로고    scopus 로고
    • Distinct FAK-Src activation events promote β5β1 and β4β1 integrin-stimulated neuroblastoma cell motility
    • L. Wu, J. A. Bernard-Triflo, Y. Lim et al., "Distinct FAK-Src activation events promote β5β1 and β4β1 integrin-stimulated neuroblastoma cell motility," Oncogene, vol. 27, no. 10, pp. 1439-1448, 2008.
    • (2008) Oncogene , vol.27 , Issue.10 , pp. 1439-1448
    • Wu, L.1    Bernard-Triflo, J.A.2    Lim, Y.3
  • 34
    • 66449095667 scopus 로고    scopus 로고
    • A pleiotropically acting microRNA, MIR-31, inhibits breast cancer metastasis
    • S. Valastyan, F. Reinhardt, N. Benaich et al., "A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis," Cell, vol. 137, no. 6, pp. 1032-1046, 2009.
    • (2009) Cell , vol.137 , Issue.6 , pp. 1032-1046
    • Valastyan, S.1    Reinhardt, F.2    Benaich, N.3
  • 35
    • 84859243460 scopus 로고    scopus 로고
    • Akt and RhoA inhibition promotes anoikis of aggregated B16F10 melanoma cells
    • O. Goundiam, M.-D. Nagel, and M. Vayssade, "Akt and RhoA inhibition promotes anoikis of aggregated B16F10 melanoma cells," Cell Biology International, vol. 36, no. 3, pp. 311-319, 2012.
    • (2012) Cell Biology International , vol.36 , Issue.3 , pp. 311-319
    • Goundiam, O.1    Nagel, M.-D.2    Vayssade, M.3
  • 36
    • 77953067173 scopus 로고    scopus 로고
    • MicroRNA-140 plays dual roles in both cartilage development and homeostasis
    • S. Miyaki, T. Sato, A. Inoue et al., "MicroRNA-140 plays dual roles in both cartilage development and homeostasis," Genes and Development, vol. 24, no. 11, pp. 1173-1185, 2010.
    • (2010) Genes and Development , vol.24 , Issue.11 , pp. 1173-1185
    • Miyaki, S.1    Sato, T.2    Inoue, A.3
  • 37
    • 84885035826 scopus 로고    scopus 로고
    • Dual role of MIR-21 in CD4+ T-cells: Activation-induced MIR-21 supports survival of memory T-cells and regulates CCR7 expression in naive T-cells
    • K. Smigielska-Czepiel, A. van den Berg, P. Jellema et al., "Dual role of miR-21 in CD4+ T-cells: activation-induced miR-21 supports survival of memory T-cells and regulates CCR7 expression in naive T-cells," PLoS ONE, vol. 8, no. 10, Article ID e76217, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.10
    • Smigielska-Czepiel, K.1    Berg Den A.Van2    Jellema, P.3
  • 38
    • 77957981791 scopus 로고    scopus 로고
    • MiRNA-451 plays a role as tumor suppressor in human glioma cells
    • Y. Nan, L. Han, A. Zhang et al., "MiRNA-451 plays a role as tumor suppressor in human glioma cells," Brain Research, vol. 1359, pp. 14-21, 2010.
    • (2010) Brain Research , vol.1359 , pp. 14-21
    • Nan, Y.1    Han, L.2    Zhang, A.3
  • 39
    • 84863392564 scopus 로고    scopus 로고
    • MicroRNA MIR-451 downregu-lates the PI3K/AKT pathway through CAB39 in human glioma
    • Y. Tian, Y. Nan, L. Han et al., "MicroRNA miR-451 downregu-lates the PI3K/AKT pathway through CAB39 in human glioma," International Journal of Oncology, vol. 40, no. 4, pp. 1105-1112, 2012.
    • (2012) International Journal of Oncology , vol.40 , Issue.4 , pp. 1105-1112
    • Tian, Y.1    Nan, Y.2    Han, L.3
  • 40
    • 0141753981 scopus 로고    scopus 로고
    • MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
    • J. Boudeau, A. F. Baas, M. Deak et al., "MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm," The EMBO Journal, vol. 22, no. 19, pp. 5102-5114, 2003.
    • (2003) The EMBO Journal , vol.22 , Issue.19 , pp. 5102-5114
    • Boudeau, J.1    Baas, A.F.2    Deak, M.3
  • 41
    • 77949459392 scopus 로고    scopus 로고
    • AMPK exerts dual regulatory efects on the PI3K pathway
    • R. Tao, J. Gong, X. Luo et al., "AMPK exerts dual regulatory efects on the PI3K pathway," Journal of Molecular Signaling, vol. 5, no. 1, p. 1, 2010.
    • (2010) Journal of Molecular Signaling , vol.5 , Issue.1 , pp. 1
    • Tao, R.1    Gong, J.2    Luo, X.3
  • 42
    • 80053133038 scopus 로고    scopus 로고
    • The expression and function of miRNA-451 in non-small cell lung cancer
    • X.-C. Wang, L.-L. Tian, X.-Y. Jiang et al., "The expression and function of miRNA-451 in non-small cell lung cancer," Cancer Letters, vol. 311, no. 2, pp. 203-209, 2011.
    • (2011) Cancer Letters , vol.311 , Issue.2 , pp. 203-209
    • Wang, X.-C.1    Tian, L.-L.2    Jiang, X.-Y.3
  • 43
    • 84887480653 scopus 로고    scopus 로고
    • Regulation of the MicroRNA 200b (miRNA-200b) by transcriptional regulators PEA3 and ELK-1 protein afects expression of Pin1 protein to control anoikis
    • X. Zhang, B. Zhang, J. Gao, X. Wang, and Z. Liu, "Regulation of the MicroRNA 200b (miRNA-200b) by transcriptional regulators PEA3 and ELK-1 protein afects expression of Pin1 protein to control anoikis," The Journal of Biological Chemistry, vol. 288, no. 45, pp. 32742-32752, 2013.
    • (2013) The Journal of Biological Chemistry , vol.288 , Issue.45 , pp. 32742-32752
    • Zhang, X.1    Zhang, B.2    Gao, J.3    Wang, X.4    Liu, Z.5
  • 44
    • 77954863985 scopus 로고    scopus 로고
    • Loss of MIR-200c: A marker of aggressiveness and chemoresis-tance in female reproductive cancers
    • D. R. Cochrane, E. N. Howe, N. S. Spoelstra, and J. K. Richer, "Loss of miR-200c: a marker of aggressiveness and chemoresis-tance in female reproductive cancers," Journal of Oncology, vol. 2010, Article ID 821717, 12 pages, 2010.
    • (2010) Journal of Oncology , vol.2010
    • Cochrane, D.R.1    Howe, E.N.2    Spoelstra, N.S.3    Richer, J.K.4
  • 45
    • 79955102595 scopus 로고    scopus 로고
    • Targets of MIR-200c mediate suppression of cell motility and anoikis resistance
    • E. N. Howe, D. R. Cochrane, and J. K. Richer, "Targets of miR-200c mediate suppression of cell motility and anoikis resistance," Breast Cancer Research, vol. 13, no. 2, article R45, 2011.
    • (2011) Breast Cancer Research , vol.13 , Issue.2
    • Howe, E.N.1    Cochrane, D.R.2    Richer, J.K.3
  • 46
    • 84903879534 scopus 로고    scopus 로고
    • MIR-141 and MIR-200c as markers of overall survival in early stage non-small cell lung cancer adenocarcinoma
    • R. Tejero, A. Navarro, M. Campayo et al., "miR-141 and miR-200c as markers of overall survival in early stage non-small cell lung cancer adenocarcinoma," PLoS ONE, vol. 9, no. 7, Article ID e101899, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.7
    • Tejero, R.1    Navarro, A.2    Campayo, M.3
  • 47
    • 84906860991 scopus 로고    scopus 로고
    • MIR-424-5p reversed epithelial-mesenchymal transition of anchorage-independent HCC cells by directly targeting ICAT and suppressed HCC progression
    • Y. Zhang, T. Li, P. Guo et al., "MiR-424-5p reversed epithelial-mesenchymal transition of anchorage-independent HCC cells by directly targeting ICAT and suppressed HCC progression," Scientifc Reports, vol. 4, article 6248, 2014.
    • (2014) Scientifc Reports , vol.4
    • Zhang, Y.1    Li, T.2    Guo, P.3
  • 48
    • 84904636051 scopus 로고    scopus 로고
    • Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and beta-catenin signaling in pancreatic ductal adenocarcinoma cells
    • L. Li, Z. Li, X. Kong et al., "Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and beta-catenin signaling in pancreatic ductal adenocarcinoma cells," Gastroenterology, vol. 147, no. 2, pp. 485.e18-497.e18, 2014.
    • (2014) Gastroenterology , vol.147 , Issue.2 , pp. 485e18-497e18
    • Li, L.1    Li, Z.2    Kong, X.3
  • 49
    • 84860542598 scopus 로고    scopus 로고
    • MIR-125b is an adhesion-regulated microRNA that protects mesenchymal stem cells from anoikis
    • X. Yu, D. M. Cohen, and C. S. Chen, "miR-125b is an adhesion-regulated microRNA that protects mesenchymal stem cells from anoikis," Stem Cells, vol. 30, no. 5, pp. 956-964, 2012.
    • (2012) Stem Cells , vol.30 , Issue.5 , pp. 956-964
    • Yu, X.1    Cohen, D.M.2    Chen, C.S.3
  • 51
    • 84920411025 scopus 로고    scopus 로고
    • MIR-145 expression accelerates esophageal adenocarcinoma progression by enhancing cell invasion and anoikis resistance
    • M. F. Derouet, G. Liu, and G. E. Darling, "MiR-145 expression accelerates esophageal adenocarcinoma progression by enhancing cell invasion and anoikis resistance," PLoS ONE, vol. 9, no. 12, Article ID 0115589, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.12
    • Derouet, M.F.1    Liu, G.2    Darling, G.E.3
  • 54
    • 77955171129 scopus 로고    scopus 로고
    • Targeting Smad4 links microRNA-146a to the TGF-β pathway during retinoid acid induction in acute promyelocytic leukemia cell line
    • H. Zhong, H.-R. Wang, S. Yang et al., "Targeting Smad4 links microRNA-146a to the TGF-β pathway during retinoid acid induction in acute promyelocytic leukemia cell line," International Journal of Hematology, vol. 92, no. 1, pp. 129-135, 2010.
    • (2010) International Journal of Hematology , vol.92 , Issue.1 , pp. 129-135
    • Zhong, H.1    Wang, H.-R.2    Yang, S.3
  • 55
    • 84862908996 scopus 로고    scopus 로고
    • Increased MIR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis
    • B. Xiao, E.-D. Zhu, N. Li et al., "Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis," Oncology Reports, vol. 27, no. 2, pp. 559-566, 2012.
    • (2012) Oncology Reports , vol.27 , Issue.2 , pp. 559-566
    • Xiao, B.1    Zhu, E.-D.2    Li, N.3
  • 56
    • 84865185534 scopus 로고    scopus 로고
    • MicroRNA-146a is down-regulated in gastric cancer and regulates cell proliferation and apoptosis
    • Z. Hou, L. Xie, L. Yu, X. Qian, and B. Liu, "MicroRNA-146a is down-regulated in gastric cancer and regulates cell proliferation and apoptosis," Medical Oncology, vol. 29, no. 2, pp. 886-892, 2012.
    • (2012) Medical Oncology , vol.29 , Issue.2 , pp. 886-892
    • Hou, Z.1    Xie, L.2    Yu, L.3    Qian, X.4    Liu, B.5
  • 57
    • 78650856849 scopus 로고    scopus 로고
    • MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer
    • J. Hao, S. Zhang, Y. Zhou, X. Hu, and C. Shao, "MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer," FEBS Letters, vol. 585, no. 1, pp. 207-213, 2011.
    • (2011) FEBS Letters , vol.585 , Issue.1 , pp. 207-213
    • Hao, J.1    Zhang, S.2    Zhou, Y.3    Hu, X.4    Shao, C.5
  • 58
    • 80052656886 scopus 로고    scopus 로고
    • MIR-483-3p controls proliferation in wounded epithelial cells
    • T. Bertero, C. Gastaldi, I. Bourget-Ponzio et al., "miR-483-3p controls proliferation in wounded epithelial cells," The FASEB Journal, vol. 25, no. 9, pp. 3092-3105, 2011.
    • (2011) The FASEB Journal , vol.25 , Issue.9 , pp. 3092-3105
    • Bertero, T.1    Gastaldi, C.2    Bourget-Ponzio, I.3
  • 59
    • 84867525253 scopus 로고    scopus 로고
    • Functional screening for MIRNAs targeting Smad4 identifed MIR-199a as a negative regulator of TGF-β signalling pathway
    • Y. Zhang, K.-J. Fan, Q. Sun et al., "Functional screening for miRNAs targeting Smad4 identifed miR-199a as a negative regulator of TGF-β signalling pathway," Nucleic Acids Research, vol. 40, no. 18, pp. 9286-9297, 2012.
    • (2012) Nucleic Acids Research , vol.40 , Issue.18 , pp. 9286-9297
    • Zhang, Y.1    Fan, K.-J.2    Sun, Q.3
  • 60
    • 77953408308 scopus 로고    scopus 로고
    • Physiological regulation of Akt activity and stability
    • Y. Liao and M.-C. Hung, "Physiological regulation of Akt activity and stability," American Journal of Translational Research, vol. 2, no. 1, pp. 19-42, 2010.
    • (2010) American Journal of Translational Research , vol.2 , Issue.1 , pp. 19-42
    • Liao, Y.1    Hung, M.-C.2
  • 61
    • 67650092976 scopus 로고    scopus 로고
    • Peptidyl-prolyl cis/trans isom-erase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation
    • Y. Liao, Y. Wei, X. Zhou et al., "Peptidyl-prolyl cis/trans isom-erase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation," Oncogene, vol. 28, no. 26, pp. 2436-2445, 2009.
    • (2009) Oncogene , vol.28 , Issue.26 , pp. 2436-2445
    • Liao, Y.1    Wei, Y.2    Zhou, X.3
  • 62
    • 70350728790 scopus 로고    scopus 로고
    • The epidermal growth factor receptor responsive MIR-125a represses mesenchymal morphology in ovarian cancer cells
    • K. D. Cowden Dahl, R. Dahl, J. N. Kruichak, and L. G. Hudson, "The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells," Neoplasia, vol. 11, no. 11, pp. 1208-1215, 2009.
    • (2009) Neoplasia , vol.11 , Issue.11 , pp. 1208-1215
    • Cowden Dahl, K.D.1    Dahl, R.2    Kruichak, J.N.3    Hudson, L.G.4
  • 64
    • 70349659954 scopus 로고    scopus 로고
    • On Trk-The TrkB signal transduction pathway is an increasingly important target in cancer biology
    • C. J. Tiele, Z. Li, and A. E. McKee, "On Trk-the TrkB signal transduction pathway is an increasingly important target in cancer biology," Clinical Cancer Research, vol. 15, no. 19, pp. 5962-5967, 2009.
    • (2009) Clinical Cancer Research , vol.15 , Issue.19 , pp. 5962-5967
    • Tiele, C.J.1    Li, Z.2    McKee, A.E.3
  • 65
    • 4344627055 scopus 로고    scopus 로고
    • Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
    • S. Douma, T. Van Laar, J. Zevenhoven, R. Meuwissen, E. Van Garderen, and D. S. Peeper, "Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB," Nature, vol. 430, no. 7003, pp. 1034-1039, 2004.
    • (2004) Nature , vol.430 , Issue.7003 , pp. 1034-1039
    • Douma, S.1    Van Laar, T.2    Zevenhoven, J.3    Meuwissen, R.4    Van Garderen, E.5    Peeper, D.S.6
  • 66
    • 0037166243 scopus 로고    scopus 로고
    • Protection against anoikis and down-regulation of cadherin expression by a regulatable β-catenin protein
    • Z. Weng, M. Xin, L. Pablo et al., "Protection against anoikis and down-regulation of cadherin expression by a regulatable β-catenin protein," Journal of Biological Chemistry, vol. 277, no. 21, pp. 18677-18686, 2002.
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.21 , pp. 18677-18686
    • Weng, Z.1    Xin, M.2    Pablo, L.3
  • 67
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of β-catenin with the transcription factor LEF-1
    • J. B ehrens, J. P. von Kries, M. Kühl et al.
    • J. B ehrens, J. P. von Kries, M. Kühl et al., "Functional interaction of β-catenin with the transcription factor LEF-1," Nature, vol. 382, no. 6592, pp. 638-642, 1996.
    • (1996) Nature , vol.382 , Issue.6592 , pp. 638-642
  • 69
    • 80054774352 scopus 로고    scopus 로고
    • FoxM1 promotes beta-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis
    • N. Zhang, P. Wei, A. Gong et al., "FoxM1 promotes beta-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis," Cancer Cell, vol. 20, no. 4, pp. 427-442, 2011.
    • (2011) Cancer Cell , vol.20 , Issue.4 , pp. 427-442
    • Zhang, N.1    Wei, P.2    Gong, A.3
  • 70
    • 0037417281 scopus 로고    scopus 로고
    • PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression
    • Y. Yin, Y.-X. Llu, Y. J. Jin, E. J. Hall, and J. C. Barrett, "PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression," Nature, vol. 422, no. 6931, pp. 527-531, 2003.
    • (2003) Nature , vol.422 , Issue.6931 , pp. 527-531
    • Yin, Y.1    Llu, Y.-X.2    Jin, Y.J.3    Hall, E.J.4    Barrett, J.C.5
  • 71
    • 0029977947 scopus 로고    scopus 로고
    • P53 modulation of anchorage independent growth and experimental metastasis
    • M. A. Nikiforov, K. Hagen, V. S. Ossovskaya et al., "p53 modulation of anchorage independent growth and experimental metastasis," Oncogene, vol. 13, no. 8, pp. 1709-1719, 1996.
    • (1996) Oncogene , vol.13 , Issue.8 , pp. 1709-1719
    • Nikiforov, M.A.1    Hagen, K.2    Ossovskaya, V.S.3
  • 72
    • 0032759232 scopus 로고    scopus 로고
    • Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression
    • M. Vitale, T. Di Matola, M. Bifulco, A. Casamassima, G. Fenzi, and G. Rossi, "Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression," FEBS Letters, vol. 462, no. 1-2, pp. 57-60, 1999.
    • (1999) FEBS Letters , vol.462 , Issue.1-2 , pp. 57-60
    • Vitale, M.1    Di Matola, T.2    Bifulco, M.3    Casamassima, A.4    Fenzi, G.5    Rossi, G.6
  • 73
    • 79953043006 scopus 로고    scopus 로고
    • Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM
    • Y. Wang, Y. Yu, A. Tsuyada et al., "Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM," Oncogene, vol. 30, no. 12, pp. 1470-1480, 2011.
    • (2011) Oncogene , vol.30 , Issue.12 , pp. 1470-1480
    • Wang, Y.1    Yu, Y.2    Tsuyada, A.3
  • 76
    • 49749107841 scopus 로고    scopus 로고
    • Aberrant expression of onco-genic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth
    • X. Wang, S. Tang, S.-Y. Le et al., "Aberrant expression of onco-genic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth," PLoS ONE, vol. 3, no. 7, Article ID e2557, 2008.
    • (2008) PLoS ONE , vol.3 , Issue.7
    • Wang, X.1    Tang, S.2    Le, S.-Y.3
  • 77
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • B. N. Davis, A. C. Hilyard, G. Lagna, and A. Hata, "SMAD proteins control DROSHA-mediated microRNA maturation," Nature, vol. 454, no. 7200, pp. 56-61, 2008.
    • (2008) Nature , vol.454 , Issue.7200 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 78
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defnes human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network, "Comprehensive genomic characterization defnes human glioblastoma genes and core pathways," Nature, vol. 455, no. 7216, pp. 1061-1068, 2008.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 79
    • 11144358645 scopus 로고    scopus 로고
    • High frequency of mutations of the PIK3CA gene in human cancers
    • Y. Samuels, Z. Wang, A. Bardelli et al., "High frequency of mutations of the PIK3CA gene in human cancers," Science, vol. 304, no. 5670, p. 554, 2004.
    • (2004) Science , vol.304 , Issue.5670 , pp. 554
    • Samuels, Y.1    Wang, Z.2    Bardelli, A.3
  • 80
    • 79959334964 scopus 로고    scopus 로고
    • Present and future of PI3K pathway inhibition in cancer: Perspectives and limitations
    • E. Ciraolo, F. Morello, and E. Hirsch, "Present and future of PI3K pathway inhibition in cancer: perspectives and limitations," Current Medicinal Chemistry, vol. 18, no. 18, pp. 2674-2685, 2011.
    • (2011) Current Medicinal Chemistry , vol.18 , Issue.18 , pp. 2674-2685
    • Ciraolo, E.1    Morello, F.2    Hirsch, E.3
  • 81
    • 81055124277 scopus 로고    scopus 로고
    • PI3K inhibitors for cancer treatment: Fve years of preclinical and clinical research afer BEZ235
    • S.-M. Maira, "PI3K inhibitors for cancer treatment: fve years of preclinical and clinical research afer BEZ235," Molecular Cancer Terapeutics, vol. 10, no. 11, p. 2016, 2011.
    • (2011) Molecular Cancer Terapeutics , vol.10 , Issue.11 , pp. 2016
    • Maira, S.-M.1
  • 82
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • S. A. Hahn, M. Schutte, A. T. M. Shamsul Hoque et al., "DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1," Science, vol. 271, no. 5247, pp. 350-353, 1996.
    • (1996) Science , vol.271 , Issue.5247 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Shamsul Hoque, A.T.M.3
  • 83
    • 36448936383 scopus 로고    scopus 로고
    • TGFβ-SMAD signal transduction: Molecular specifcity and functional fexibility
    • B. Schmierer and C. S. Hill, "TGFβ-SMAD signal transduction: molecular specifcity and functional fexibility," Nature Reviews Molecular Cell Biology, vol. 8, no. 12, pp. 970-982, 2007.
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.12 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 84
    • 0032528236 scopus 로고    scopus 로고
    • The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced tran-scriptional activation
    • X.-H. Feng, Y. Zhang, R.-Y. Wu, and R. Derynck, "The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced tran-scriptional activation," Genes & Development, vol. 12, no. 14, pp. 2153-2163, 1998.
    • (1998) Genes & Development , vol.12 , Issue.14 , pp. 2153-2163
    • Feng, X.-H.1    Zhang, Y.2    Wu, R.-Y.3    Derynck, R.4
  • 85
    • 84857232423 scopus 로고    scopus 로고
    • A portrait of Transforming Growth Factor β superfamily signalling: Background matters
    • D. Horbelt, A. Denkis, and P. Knaus, "A portrait of Transforming Growth Factor β superfamily signalling: background matters," International Journal of Biochemistry and Cell Biology, vol. 44, no. 3, pp. 469-474, 2012.
    • (2012) International Journal of Biochemistry and Cell Biology , vol.44 , Issue.3 , pp. 469-474
    • Horbelt, D.1    Denkis, A.2    Knaus, P.3
  • 86
    • 0036827889 scopus 로고    scopus 로고
    • Restoration of transforming growth factor β signaling by functional expression of Smad4 induces anoikis
    • M. Ramachandra, I. Atencio, A. Rahman et al., "Restoration of transforming growth factor β signaling by functional expression of Smad4 induces anoikis," Cancer Research, vol. 62, no. 21, pp. 6045-6051, 2002.
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6045-6051
    • Ramachandra, M.1    Atencio, I.2    Rahman, A.3
  • 87
    • 0030601935 scopus 로고    scopus 로고
    • Transforming growth factor-β (TGF-β) stimulates the expression of β1 integrins and adhesion by rat mesangial cells
    • S. Kagami, T. Kuhara, K. Yasutomo et al., "Transforming growth factor-β (TGF-β) stimulates the expression of β1 integrins and adhesion by rat mesangial cells," Experimental Cell Research, vol. 229, no. 1, pp. 1-6, 1996.
    • (1996) Experimental Cell Research , vol.229 , Issue.1 , pp. 1-6
    • Kagami, S.1    Kuhara, T.2    Yasutomo, K.3
  • 88
    • 84895726984 scopus 로고    scopus 로고
    • Clinical applications of microRNAs
    • P. Hydbring and G. Badalian-Very, "Clinical applications of microRNAs," F1000Research, vol. 2, article 136, 2013.
    • (2013) F1000Research , vol.2
    • Hydbring, P.1    Badalian-Very, G.2
  • 89
    • 84905503012 scopus 로고    scopus 로고
    • Terapeutic targeting of microRNAs: Current status and future challenges
    • Z. Li and T. M. Rana, "Terapeutic targeting of microRNAs: current status and future challenges," Nature Reviews Drug Discovery, vol. 13, no. 8, pp. 622-638, 2014.
    • (2014) Nature Reviews Drug Discovery , vol.13 , Issue.8 , pp. 622-638
    • Li, Z.1    Rana, T.M.2
  • 90
    • 84905499878 scopus 로고    scopus 로고
    • MicroRNA-34a: A potential therapeutic target in human cancer
    • X. J. Li, Z. J. Ren, and J. H. Tang, "MicroRNA-34a: a potential therapeutic target in human cancer," Cell Death & Disease, vol. 5, no. 7, Article ID e1327, 2014.
    • (2014) Cell Death & Disease , vol.5 , Issue.7
    • Li, X.J.1    Ren, Z.J.2    Tang, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.