-
2
-
-
60149088848
-
Origins and mechanisms of miRNAs and siRNAs
-
Carthew R.W., Sontheimer E.J. Origins and mechanisms of miRNAs and siRNAs. Cell 2009, 136:642-655.
-
(2009)
Cell
, vol.136
, pp. 642-655
-
-
Carthew, R.W.1
Sontheimer, E.J.2
-
3
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
4
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He L., Hannon G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 2004, 5:522-531.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
5
-
-
0038343499
-
MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing
-
Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 2003, 113:673-676.
-
(2003)
Cell
, vol.113
, pp. 673-676
-
-
Ambros, V.1
-
7
-
-
47849125676
-
MicroRNAs: new regulators of immune cell development and function
-
Baltimore D., Boldin M.P., O'Connell R.M., Rao D.S., Taganov K.D. MicroRNAs: new regulators of immune cell development and function. Nat. Immunol. 2008, 9:839-845.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 839-845
-
-
Baltimore, D.1
Boldin, M.P.2
O'Connell, R.M.3
Rao, D.S.4
Taganov, K.D.5
-
10
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J., Getz G., Miska E.A., Alvarez-Saavedra E., Lamb J., Peck D., Sweet-Cordero A., Ebert B.L., Mak R.H., Ferrando A.A., Downing J.R., Jacks T., Horvitz H.R., Golub T.R. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
11
-
-
71049172899
-
Novel rank-based statistical methods reveal microRNAs with differential expression in multiple cancer types
-
Navon R., Wang H., Steinfeld I., Tsalenko A., Ben-Dor A., Yakhini Z. Novel rank-based statistical methods reveal microRNAs with differential expression in multiple cancer types. PLoS ONE 2009, 4:e8003.
-
(2009)
PLoS ONE
, vol.4
-
-
Navon, R.1
Wang, H.2
Steinfeld, I.3
Tsalenko, A.4
Ben-Dor, A.5
Yakhini, Z.6
-
12
-
-
1642588228
-
Pancreatic cancer
-
Li D., Xie K., Wolff R., Abbruzzese J.L. Pancreatic cancer. Lancet 2004, 363:1049-1057.
-
(2004)
Lancet
, vol.363
, pp. 1049-1057
-
-
Li, D.1
Xie, K.2
Wolff, R.3
Abbruzzese, J.L.4
-
13
-
-
21344448369
-
Current diagnosis and treatment of pancreatic cancer in China
-
Guo X., Cui Z. Current diagnosis and treatment of pancreatic cancer in China. Pancreas 2005, 31:13-22.
-
(2005)
Pancreas
, vol.31
, pp. 13-22
-
-
Guo, X.1
Cui, Z.2
-
14
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Thun M.J. Cancer statistics, 2009. CA Cancer J. Clin. 2009, 59:225-249.
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
15
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B., Kinzler K.W. Cancer genes and the pathways they control. Nat. Med. 2004, 10:789-799.
-
(2004)
Nat. Med.
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
16
-
-
34249898611
-
Molecular genetics of pancreatic intraepithelial neoplasia
-
Feldmann G., Beaty R., Hruban R.H., Maitra A. Molecular genetics of pancreatic intraepithelial neoplasia. J. Hepatobiliary Pancreat. Surg. 2007, 14:224-232.
-
(2007)
J. Hepatobiliary Pancreat. Surg.
, vol.14
, pp. 224-232
-
-
Feldmann, G.1
Beaty, R.2
Hruban, R.H.3
Maitra, A.4
-
17
-
-
70350425809
-
MicroRNAs: novel diagnostic and therapeutic tools for pancreatic ductal adenocarcinoma?
-
Mardin W.A., Mees S.T. MicroRNAs: novel diagnostic and therapeutic tools for pancreatic ductal adenocarcinoma?. Ann. Surg. Oncol. 2009, 16:3183-3189.
-
(2009)
Ann. Surg. Oncol.
, vol.16
, pp. 3183-3189
-
-
Mardin, W.A.1
Mees, S.T.2
-
18
-
-
77951223405
-
MicroRNA in pancreatic cancer: pathological, diagnostic and therapeutic implications
-
Rachagani S., Kumar S., Batra S.K. MicroRNA in pancreatic cancer: pathological, diagnostic and therapeutic implications. Cancer Lett. 2010, 292:8-16.
-
(2010)
Cancer Lett.
, vol.292
, pp. 8-16
-
-
Rachagani, S.1
Kumar, S.2
Batra, S.K.3
-
19
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Angenendt P., Mankoo P., Carter H., Kamiyama H., Jimeno A., Hong S.M., Fu B., Lin M.T., Calhoun E.S., Kamiyama M., Walter K., Nikolskaya T., Nikolsky Y., Hartigan J., Smith D.R., Hidalgo M., Leach S.D., Klein A.P., Jaffee E.M., Goggins M., Maitra A., Iacobuzio-Donahue C., Eshleman J.R., Kern S.E., Hruban R.H., Karchin R., Papadopoulos N., Parmigiani G., Vogelstein B., Velculescu V.E., Kinzler K.W. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008, 321:1801-1806.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Kamiyama, H.9
Jimeno, A.10
Hong, S.M.11
Fu, B.12
Lin, M.T.13
Calhoun, E.S.14
Kamiyama, M.15
Walter, K.16
Nikolskaya, T.17
Nikolsky, Y.18
Hartigan, J.19
Smith, D.R.20
Hidalgo, M.21
Leach, S.D.22
Klein, A.P.23
Jaffee, E.M.24
Goggins, M.25
Maitra, A.26
Iacobuzio-Donahue, C.27
Eshleman, J.R.28
Kern, S.E.29
Hruban, R.H.30
Karchin, R.31
Papadopoulos, N.32
Parmigiani, G.33
Vogelstein, B.34
Velculescu, V.E.35
Kinzler, K.W.36
more..
-
21
-
-
0034032009
-
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression
-
Wilentz R.E., Iacobuzio-Donahue C.A., Argani P., McCarthy D.M., Parsons J.L., Yeo C.J., Kern S.E., Hruban R.H. Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res. 2000, 60:2002-2006.
-
(2000)
Cancer Res.
, vol.60
, pp. 2002-2006
-
-
Wilentz, R.E.1
Iacobuzio-Donahue, C.A.2
Argani, P.3
McCarthy, D.M.4
Parsons, J.L.5
Yeo, C.J.6
Kern, S.E.7
Hruban, R.H.8
-
22
-
-
0033891752
-
Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas: a new marker of DPC4 inactivation
-
Wilentz R.E., Su G.H., Dai J.L., Sparks A.B., Argani P., Sohn T.A., Yeo C.J., Kern S.E., Hruban R.H. Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas: a new marker of DPC4 inactivation. Am. J. Pathol. 2000, 156:37-43.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 37-43
-
-
Wilentz, R.E.1
Su, G.H.2
Dai, J.L.3
Sparks, A.B.4
Argani, P.5
Sohn, T.A.6
Yeo, C.J.7
Kern, S.E.8
Hruban, R.H.9
-
23
-
-
0035004797
-
Allelic loss is often the first hit in the biallelic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis
-
Luttges J., Galehdari H., Brocker V., Schwarte-Waldhoff I., Henne-Bruns D., Kloppel G., Schmiegel W., Hahn S.A. Allelic loss is often the first hit in the biallelic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis. Am. J. Pathol. 2001, 158:1677-1683.
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 1677-1683
-
-
Luttges, J.1
Galehdari, H.2
Brocker, V.3
Schwarte-Waldhoff, I.4
Henne-Bruns, D.5
Kloppel, G.6
Schmiegel, W.7
Hahn, S.A.8
-
24
-
-
78650856849
-
MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer
-
Hao J., Zhang S., Zhou Y., Hu X., Shao C. MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer. FEBS Lett. 2011, 585:207-213.
-
(2011)
FEBS Lett.
, vol.585
, pp. 207-213
-
-
Hao, J.1
Zhang, S.2
Zhou, Y.3
Hu, X.4
Shao, C.5
-
25
-
-
0036848885
-
Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells
-
Peng B., Fleming J.B., Breslin T., Grau A.M., Fojioka S., Abbruzzese J.L., Evans D.B., Ayers D., Wathen K., Wu T., Robertson K.D., Chiao P.J. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. Clin. Cancer Res. 2002, 8:3628-3638.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3628-3638
-
-
Peng, B.1
Fleming, J.B.2
Breslin, T.3
Grau, A.M.4
Fojioka, S.5
Abbruzzese, J.L.6
Evans, D.B.7
Ayers, D.8
Wathen, K.9
Wu, T.10
Robertson, K.D.11
Chiao, P.J.12
-
26
-
-
70249098042
-
Dual role of Ski in pancreatic cancer cells: tumor-promoting versus metastasis-suppressive function
-
Wang P., Chen Z., Meng Z.Q., Fan J., Luo J.M., Liang W., Lin J.H., Zhou Z.H., Chen H., Wang K., Shen Y.H., Xu Z.D., Liu L.M. Dual role of Ski in pancreatic cancer cells: tumor-promoting versus metastasis-suppressive function. Carcinogenesis 2009, 30:1497-1506.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1497-1506
-
-
Wang, P.1
Chen, Z.2
Meng, Z.Q.3
Fan, J.4
Luo, J.M.5
Liang, W.6
Lin, J.H.7
Zhou, Z.H.8
Chen, H.9
Wang, K.10
Shen, Y.H.11
Xu, Z.D.12
Liu, L.M.13
-
27
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y., Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003, 113:685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
28
-
-
0034703083
-
Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta
-
Pardali K., Kurisaki A., Moren A., ten Dijke P., Kardassis D., Moustakas A. Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta. J. Biol. Chem. 2000, 275:29244-29256.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29244-29256
-
-
Pardali, K.1
Kurisaki, A.2
Moren, A.3
ten Dijke, P.4
Kardassis, D.5
Moustakas, A.6
-
29
-
-
0034596993
-
Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta
-
Feng X.H., Lin X., Derynck R. Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta. EMBO J. 2000, 19:5178-5193.
-
(2000)
EMBO J.
, vol.19
, pp. 5178-5193
-
-
Feng, X.H.1
Lin, X.2
Derynck, R.3
-
30
-
-
0037167519
-
Id: a target of BMP signaling
-
Miyazono K., Miyazawa K. Id: a target of BMP signaling. Sci. STKE 2002, 2002:pe40.
-
(2002)
Sci. STKE
, vol.2002
-
-
Miyazono, K.1
Miyazawa, K.2
-
31
-
-
2942536704
-
Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein
-
Kowanetz M., Valcourt U., Bergstrom R., Heldin C.H., Moustakas A. Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol. Cell. Biol. 2004, 24:4241-4254.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4241-4254
-
-
Kowanetz, M.1
Valcourt, U.2
Bergstrom, R.3
Heldin, C.H.4
Moustakas, A.5
-
32
-
-
77955033963
-
MiRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer
-
Yu S., Lu Z., Liu C., Meng Y., Ma Y., Zhao W., Liu J., Yu J., Chen J. MiRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer. Cancer Res. 2010, 70:6015-6025.
-
(2010)
Cancer Res.
, vol.70
, pp. 6015-6025
-
-
Yu, S.1
Lu, Z.2
Liu, C.3
Meng, Y.4
Ma, Y.5
Zhao, W.6
Liu, J.7
Yu, J.8
Chen, J.9
-
33
-
-
47549090432
-
TGFbeta in cancer
-
Massague J. TGFbeta in cancer. Cell 2008, 134:215-230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
34
-
-
61749097816
-
Tgf-beta superfamily signaling in embryonic development and homeostasis
-
Wu M.Y., Hill C.S. Tgf-beta superfamily signaling in embryonic development and homeostasis. Dev. Cell 2009, 16:329-343.
-
(2009)
Dev. Cell
, vol.16
, pp. 329-343
-
-
Wu, M.Y.1
Hill, C.S.2
-
35
-
-
77949262341
-
Increased expression of miR-421 in human gastric carcinoma and its clinical association
-
Jiang Z., Guo J., Xiao B., Miao Y., Huang R., Li D., Zhang Y. Increased expression of miR-421 in human gastric carcinoma and its clinical association. J. Gastroenterol. 2010, 45:17-23.
-
(2010)
J. Gastroenterol.
, vol.45
, pp. 17-23
-
-
Jiang, Z.1
Guo, J.2
Xiao, B.3
Miao, Y.4
Huang, R.5
Li, D.6
Zhang, Y.7
-
36
-
-
76549127430
-
ATM is down-regulated by N-Myc-regulated microRNA-421
-
Hu H., Du L., Nagabayashi G., Seeger R.C., Gatti R.A. ATM is down-regulated by N-Myc-regulated microRNA-421. Proc. Natl. Acad. Sci. USA 2010, 107:1506-1511.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 1506-1511
-
-
Hu, H.1
Du, L.2
Nagabayashi, G.3
Seeger, R.C.4
Gatti, R.A.5
|