-
1
-
-
35949002429
-
Malignant astrocytic glioma: Genetics, biology, and paths to treatment
-
DOI 10.1101/gad.1596707
-
Furnari FB, Fenton T, Bachoo RM, et al: Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev 21: 2683-2710, 2007. (Pubitemid 350070717)
-
(2007)
Genes and Development
, vol.21
, Issue.21
, pp. 2683-2710
-
-
Furnari, F.B.1
Fenton, T.2
Bachoo, R.M.3
Mukasa, A.4
Stommel, J.M.5
Stegh, A.6
Hahn, W.C.7
Ligon, K.L.8
Louis, D.N.9
Brennan, C.10
Chin, L.11
DePinho, R.A.12
Cavenee, W.K.13
-
2
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, Shu HK, Wen PY and Olson JJ: Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 60: 166-193, 2010.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 166-193
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
Shu, H.K.4
Wen, P.Y.5
Olson, J.J.6
-
3
-
-
52049096593
-
MIR-451 and imatinib mesylate inhibit tumor growth of glioblastoma stem cells
-
Gal H, Pandi G, Kanner AA, et al: MIR-451 and imatinib mesylate inhibit tumor growth of glioblastoma stem cells. Biochem Biophys Res Commun 376: 86-90, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 86-90
-
-
Gal, H.1
Pandi, G.2
Kanner, A.A.3
-
4
-
-
77956464355
-
MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
-
Zhang CZ, Zhang JX, Zhang AL, et al: MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma. Mol Cancer 9: 229, 2010.
-
(2010)
Mol Cancer
, vol.9
, pp. 229
-
-
Zhang, C.Z.1
Zhang, J.X.2
Zhang, A.L.3
-
5
-
-
57349146677
-
MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin
-
Liu T, Tang H, Lang Y, Liu M and Li X: MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett 273: 233-242, 2009.
-
(2009)
Cancer Lett
, vol.273
, pp. 233-242
-
-
Liu, T.1
Tang, H.2
Lang, Y.3
Liu, M.4
Li, X.5
-
6
-
-
66849124564
-
MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance
-
Moriyama T, Ohuchida K, Mizumoto K, et al: MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance. Mol Cancer Ther 8: 1067-1074, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1067-1074
-
-
Moriyama, T.1
Ohuchida, K.2
Mizumoto, K.3
-
7
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R and Rajewsky N: Widespread changes in protein synthesis induced by microRNAs. Nature 455: 58-63, 2008.
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
8
-
-
54549108798
-
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
-
Tay Y, Zhang J, Thomson AM, Lim B and Rigoutsos I: MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 455: 1124-1128, 2008.
-
(2008)
Nature
, vol.455
, pp. 1124-1128
-
-
Tay, Y.1
Zhang, J.2
Thomson, A.M.3
Lim, B.4
Rigoutsos, I.5
-
9
-
-
67749132423
-
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
-
Chi SW, Zang JB, Mele A and Darnell RB: Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460: 479-486, 2009.
-
(2009)
Nature
, vol.460
, pp. 479-486
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
Darnell, R.B.4
-
10
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
DOI 10.1038/nrg1379
-
He L and Hannon GJ: MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5: 522-531, 2004. (Pubitemid 38868508)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.7
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
11
-
-
33644750115
-
MiRBase: MicroRNA sequences, targets and gene nomenclature
-
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ: miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34: D140-D144, 2006.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
Van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
12
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V: The functions of animal microRNAs. Nature 431: 350-355, 2004.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
13
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297, 2004.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
14
-
-
33645321647
-
MicroRNAs in cell proliferation, cell death, and tumorigenesis
-
Hwang HW and Mendell JT: MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 94: 776-780, 2006.
-
(2006)
Br J Cancer
, vol.94
, pp. 776-780
-
-
Hwang, H.W.1
Mendell, J.T.2
-
15
-
-
34249061737
-
MicroRNAs as cancer players: Potential clinical and biological effects
-
DOI 10.1089/dna.2006.0544
-
Bandres E, Agirre X, Ramirez N, Zarate R and Garcia-Foncillas J: MicroRNAs as cancer players: potential clinical and biological effects. DNA Cell Biol 26: 273-282, 2007. (Pubitemid 46799176)
-
(2007)
DNA and Cell Biology
, vol.26
, Issue.5
, pp. 273-282
-
-
Bandres, E.E.1
Agirre, X.2
Ramirez, N.3
Zarate, R.4
Garcia-Foncillas, J.5
-
16
-
-
0036883715
-
Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer
-
DOI 10.1002/gcc.10122
-
Mahlamaki EH, Barlund M, Tanner M, et al: Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer. Genes Chromosomes Cancer 35: 353-358, 2002. (Pubitemid 35246993)
-
(2002)
Genes Chromosomes and Cancer
, vol.35
, Issue.4
, pp. 353-358
-
-
Mahlamaki, E.H.1
Barlund, M.2
Tanner, M.3
Gorunova, L.4
Hoglund, M.5
Karhu, R.6
Kallioniemi, A.7
-
17
-
-
0036570356
-
Targets of gene amplification and overexpression at 17q in gastric cancer
-
Varis A, Wolf M, Monni O, et al: Targets of gene amplification and overexpression at 17q in gastric cancer. Cancer Res 62: 2625-2629, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 2625-2629
-
-
Varis, A.1
Wolf, M.2
Monni, O.3
-
18
-
-
77957981791
-
MiRNA-451 plays a role as tumor suppressor in human glioma cells
-
Nan Y, Han L, Zhang A, et al: MiRNA-451 plays a role as tumor suppressor in human glioma cells. Brain Res 1359: 14-21, 2010.
-
(2010)
Brain Res
, vol.1359
, pp. 14-21
-
-
Nan, Y.1
Han, L.2
Zhang, A.3
-
19
-
-
0037250152
-
STRING: A database of predicted functional associations between proteins
-
DOI 10.1093/nar/gkg034
-
von Mering C, Huynen M, Jaeggi D, Schmidt S, Bork P and Snel B: STRING: a database of predicted functional associations between proteins. Nucleic Acids Res 31: 258-261, 2003. (Pubitemid 36150379)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.1
, pp. 258-261
-
-
Von, M.C.1
Huynen, M.2
Jaeggi, D.3
Schmidt, S.4
Bork, P.5
Snel, B.6
-
20
-
-
0033982936
-
KEGG: Kyoto Encyclopedia of Genes and Genomes
-
Kanehisa M and Goto S: KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28: 27-30, 2000. (Pubitemid 30047706)
-
(2000)
Nucleic Acids Research
, vol.28
, Issue.1
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
22
-
-
33747849920
-
RNAhybrid: MicroRNA target prediction easy, fast and flexible
-
DOI 10.1093/nar/gkl243
-
Kruger J and Rehmsmeier M: RNAhybrid: microRNA target prediction easy, fast and flexible. Nucleic Acids Res 34: W451-W454, 2006. (Pubitemid 44529811)
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.WEB. SERV. ISS.
-
-
Kruger, J.1
Rehmsmeier, M.2
-
23
-
-
33645878924
-
Suppression of EGFR expression by antisense or small interference RNA inhibits U251 glioma cell growth in vitro and in vivo
-
Kang CS, Zhang ZY, Jia ZF, et al: Suppression of EGFR expression by antisense or small interference RNA inhibits U251 glioma cell growth in vitro and in vivo. Cancer Gene Ther 13: 530-538, 2006.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 530-538
-
-
Kang, C.S.1
Zhang, Z.Y.2
Jia, Z.F.3
-
24
-
-
77953001932
-
AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion
-
Zhang J, Han L, Zhang A, et al: AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion. Oncol Rep 24: 65-72, 2010.
-
(2010)
Oncol Rep
, vol.24
, pp. 65-72
-
-
Zhang, J.1
Han, L.2
Zhang, A.3
-
25
-
-
77649312099
-
Regulation of the transcription factor NF-kappaB1 by microRNA-9 in human gastric adenocarcinoma
-
Wan HY, Guo LM, Liu T, Liu M, Li X and Tang H: Regulation of the transcription factor NF-kappaB1 by microRNA-9 in human gastric adenocarcinoma. Mol Cancer 9: 16, 2010.
-
(2010)
Mol Cancer
, vol.9
, pp. 16
-
-
Wan, H.Y.1
Guo, L.M.2
Liu, T.3
Liu, M.4
Li, X.5
Tang, H.6
-
26
-
-
0036849331
-
PKB binding proteins: Getting in on the Akt
-
DOI 10.1016/S0092-8674(02)01083-8
-
Brazil DP, Park J and Hemmings BA: PKB binding proteins. Getting in on the Akt. Cell 111: 293-303, 2002. (Pubitemid 35341386)
-
(2002)
Cell
, vol.111
, Issue.3
, pp. 293-303
-
-
Brazil, D.P.1
Park, J.2
Hemmings, B.A.3
-
27
-
-
6344282984
-
Human intestinal epithelial cell survival and anoikis: Differentiation state-distinct regulation and roles of protein kinase B/Akt isoforms
-
DOI 10.1074/jbc.M405323200
-
Dufour G, Demers MJ, Gagne D, et al: Human intestinal epithelial cell survival and anoikis. Differentiation state-distinct regulation and roles of protein kinase B/Akt isoforms. J Biol Chem 279: 44113-44122, 2004. (Pubitemid 39403045)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.42
, pp. 44113-44122
-
-
Dufourt, G.1
Demers, M.-J.2
Gagne, D.3
Dydensborg, A.B.4
Teller, I.C.5
Bouchard, V.6
Degongre, I.7
Beaulieu, J.-F.8
Cheng, J.Q.9
Fujita, N.10
Tsuruo, T.11
Vallee, K.12
Vachon, P.H.13
-
29
-
-
0141753981
-
MO25alpha/beta interact with STRAalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
-
DOI 10.1093/emboj/cdg490
-
Boudeau J, Baas AF, Deak M, et al: MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J 22: 5102-5114, 2003. (Pubitemid 37222030)
-
(2003)
EMBO Journal
, vol.22
, Issue.19
, pp. 5102-5114
-
-
Boudeau, J.1
Baas, A.F.2
Deak, M.3
Morrice, N.A.4
Kieloch, A.5
Schutkowski, M.6
Prescott, A.R.7
Clevers, H.C.8
Alessi, D.R.9
-
30
-
-
0742270597
-
Crystal structure of MO25alpha in complex with the C terminus of the pseudo kinase STE20-related adaptor
-
DOI 10.1038/nsmb716
-
Milburn CC, Boudeau J, Deak M, Alessi DR and van Aalten DM: Crystal structure of MO25 alpha in complex with the C terminus of the pseudo kinase STE20-related adaptor. Nat Struct Mol Biol 11: 193-200, 2004. (Pubitemid 38146524)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.2
, pp. 193-200
-
-
Milburn, C.C.1
Boudeau, J.2
Deak, M.3
Alessi, D.R.4
Van Aalten, D.M.F.5
-
31
-
-
1842581909
-
Comprehensive Proteomic Analysis of Human Par Protein Complexes Reveals an Interconnected Protein Network
-
DOI 10.1074/jbc.M312171200
-
Brajenovic M, Joberty G, Kuster B, Bouwmeester T and Drewes G: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. J Biol Chem 279: 12804-12811, 2004. (Pubitemid 38445853)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.13
, pp. 12804-12811
-
-
Brajenovic, M.1
Joberty, G.2
Kuster, B.3
Bouwmeester, T.4
Drewes, G.5
-
32
-
-
0038614742
-
Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD
-
DOI 10.1093/emboj/cdg292
-
Baas AF, Boudeau J, Sapkota GP, et al: Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. EMBO J 22: 3062-3072, 2003. (Pubitemid 36758626)
-
(2003)
EMBO Journal
, vol.22
, Issue.12
, pp. 3062-3072
-
-
Baas, A.F.1
Boudeau, J.2
Sapkota, G.P.3
Smit, L.4
Medema, R.5
Morrice, N.A.6
Alessi, D.R.7
Clevers, H.C.8
-
33
-
-
0032495530
-
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
-
DOI 10.1038/34432
-
Hemminki A, Markie D, Tomlinson I, et al: A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 391: 184-187, 1998. (Pubitemid 28092478)
-
(1998)
Nature
, vol.391
, Issue.6663
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
Loukola, A.6
Bignell, G.7
Warren, W.8
Aminoff, M.9
Hoglund, P.10
Jarvinen, H.11
Kristo, P.12
Pelin, K.13
Ridanpaa, M.14
Salovaara, R.15
Toro, T.16
Bodmer, W.17
Olschwang, S.18
Olsen, A.S.19
Stratton, M.R.20
De La, C.A.21
Aaltonen, L.A.22
more..
-
34
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
DOI 10.1038/ng0198-38
-
Jenne DE, Reimann H, Nezu J, et al: Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet 18: 38-43, 1998. (Pubitemid 28027876)
-
(1998)
Nature Genetics
, vol.18
, Issue.1
, pp. 38-43
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.-I.3
Friedel, W.4
Loff, S.5
Jeschke, R.6
Muller, O.7
Back, W.8
Zimmer, M.9
-
35
-
-
0038199737
-
Management of cellular energy by the AMP-activated protein kinase system
-
DOI 10.1016/S0014-5793(03)00560-X
-
Hardie DG, Scott JW, Pan DA and Hudson ER: Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett 546: 113-120, 2003. (Pubitemid 36782291)
-
(2003)
FEBS Letters
, vol.546
, Issue.1
, pp. 113-120
-
-
Hardie, D.G.1
Scott, J.W.2
Pan, D.A.3
Hudson, E.R.4
-
36
-
-
0345107247
-
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
-
Hawley SA, Boudeau J, Reid JL, et al: Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2: 28, 2003.
-
(2003)
J Biol
, vol.2
, pp. 28
-
-
Hawley, S.A.1
Boudeau, J.2
Reid, J.L.3
-
37
-
-
10744230065
-
LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
-
DOI 10.1016/j.cub.2003.10.031
-
Woods A, Johnstone SR, Dickerson K, et al: LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr Biol 13: 2004-2008, 2003. (Pubitemid 37425212)
-
(2003)
Current Biology
, vol.13
, Issue.22
, pp. 2004-2008
-
-
Woods, A.1
Johnstone, S.R.2
Dickerson, K.3
Leiper, F.C.4
Fryer, L.G.D.5
Neumann, D.6
Schlattner, U.7
Wallimann, T.8
Carlson, M.9
Carling, D.10
-
38
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
DOI 10.1146/annurev.biochem.70.1.535
-
Vanhaesebroeck B, Leevers SJ, Ahmadi K, et al: Synthesis and function of 3-phosphorylated inositol lipids. Annu Rev Biochem 70: 535-602, 2001. (Pubitemid 32662219)
-
(2001)
Annual Review of Biochemistry
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
Timms, J.4
Katso, R.5
Driscoll, P.C.6
Woscholski, R.7
Parker, P.J.8
Waterfield, M.D.9
-
39
-
-
57449104947
-
PI3K signaling in glioma-animal models and therapeutic challenges
-
Cheng CK, Fan QW and Weiss WA: PI3K signaling in glioma-animal models and therapeutic challenges. Brain Pathol 19: 112-120, 2009.
-
(2009)
Brain Pathol
, vol.19
, pp. 112-120
-
-
Cheng, C.K.1
Fan, Q.W.2
Weiss, W.A.3
-
40
-
-
77949459392
-
AMPK exerts dual regulatory effects on the PI3K pathway
-
Tao R, Gong J, Luo X, et al: AMPK exerts dual regulatory effects on the PI3K pathway. J Mol Signal 5: 1, 2010.
-
(2010)
J Mol Signal
, vol.5
, pp. 1
-
-
Tao, R.1
Gong, J.2
Luo, X.3
|