Down-regulation of MicroRNA-494 via loss of SMAD4 increases FOXM1 and β-catenin signaling in pancreatic ductal adenocarcinoma cells

Gastroenterology

Volumn 147, Issue 2, 2014, Pages

  Li, Lei ^a   Li, Zhaoshen ^a   Kong, Xiangyu ^a,b   Xie, Dacheng ^c   Jia, Zhiliang ^b   Jiang, Weihua ^b,c   Cui, Jiujie ^b,c   Du, Yiqi ^a   Wei, Daoyan ^b   Huang, Suyun ^b   Xie, Keping ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS   (United States)

^c SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

Author keywords

Gene Regulation; Pancreatic Cancer; Signal Transduction; Tumor Progression

Indexed keywords

BETA CATENIN; FORKHEAD BOX M1 PROTEIN; GEMCITABINE; MICRORNA; MICRORNA 494; SMAD4 PROTEIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADENOCARCINOMA CELL LINE; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPC 1 CELL LINE; BIOINFORMATICS; CANCER GROWTH; CANCER SURVIVAL; CANCER TISSUE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CHEMOSENSITIVITY; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; LIVER METASTASIS; MALE; NONHUMAN; PANC 1 CELL LINE; PANCREAS ADENOCARCINOMA; PANCREAS METASTASIS; PRIORITY JOURNAL; PROTEIN DEPLETION; SURVIVAL TIME; TRANSGENICS; TUMOR XENOGRAFT;

GENE REGULATION; PANCREATIC CANCER; SIGNAL TRANSDUCTION; TUMOR PROGRESSION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BETA CATENIN; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DEOXYCYTIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; MIDDLE AGED; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD4 PROTEIN; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84904636051     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.04.048     Document Type: Article

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