A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation

Cell Reports

Volumn 12, Issue 6, 2015, Pages 937-943

  Yang, Guang ^a,c   Murashige, Danielle S ^a,d   Humphrey, Sean J ^a,b   James, David E ^a,c  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B; PROTEIN SIN1; S6 KINASE; UNCLASSIFIED DRUG; 2-(4-CHLOROPHENYL)-1-(4-(7-HYDROXY-5-METHYL-6,7-DIHYDRO-5H-CYCLOPENTA(D)PYRIMIDIN-4-YL)PIPERAZIN-1-YL)-3-(ISOPROPYLAMINO)PROPAN-1-ONE; ENZYME INHIBITOR; MAPKAP1 PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RIBOSOMAL PROTEIN S6 KINASE, 70KD, POLYPEPTIDE 1; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FIBROBLAST; HEK293 CELL LINE; HELA CELL LINE; IMMUNOBLOTTING; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE; ENZYME INHIBITORS; HEK293 CELLS; HELA CELLS; HUMANS; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-AKT; PYRIMIDINES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84947023702     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.07.016     Document Type: Article

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