Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivo

Neurochemistry International

Volumn 90, Issue , 2015, Pages 152-165

  Asuni, Ayodeji A ^a,b   Guridi, Maitea ^a   Sanchez, Sandrine ^a   Sadowski, Martin J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Antioxidant; Astrocytes; ME7; Neurodegeneration; Peroxiredoxin 6; Prion

Indexed keywords

COBALT CHLORIDE; HYDROGEN PEROXIDE; PEROXIREDOXIN 6; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; PRION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTE; BEHAVIOR CHANGE; CELL HYPOXIA; CELL METABOLISM; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE SEVERITY; DRUG MECHANISM; EMBRYO; FEMALE; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL TIME; ANIMAL; C57BL MOUSE; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; PRION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; HYDROGEN PEROXIDE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; OXIDATIVE STRESS; PEROXIREDOXIN VI; PRIONS; REACTIVE OXYGEN SPECIES;

EID: 84947022002     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2015.08.006     Document Type: Article

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