Dysfunction of mitochondrial dynamics in the brains of scrapie-infected mice

Biochemical and Biophysical Research Communications

Volumn 448, Issue 2, 2014, Pages 157-162

  Choi, Hong Seok ^a   Choi, Yeong Gon ^a   Shin, Hae Young ^a   Oh, Jae Min ^a   Park, Jeong Ho ^a   Kim, Jae Il ^b   Carp, Richard I ^c   Choi, Eun Kyoung ^a   Kim, Yong Sun ^a  

^a Hallym University   (South Korea)

^b Pukyong National University   (South Korea)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Fission; Mitochondrial dysfunction; Mitochondrial fusion; Prion disease; Scrapie

Indexed keywords

DYNAMIN; DYNAMIN LIKE PROTEIN 1; FISSION 1 PROTEIN; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; MITOFUSIN 2; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; CYTOSOL; CYTOSOLIC FRACTION; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOBLOTTING; MITOCHONDRIAL DYNAMICS; MORPHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCRAPIE; UPREGULATION;

ANIMALIA; MUS;

FISSION; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL FUSION; PRION DISEASE; SCRAPIE;

ANIMALS; BRAIN; CYTOSOL; DISEASE MODELS, ANIMAL; DYNAMINS; GTP PHOSPHOHYDROLASES; HIPPOCAMPUS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; PRPSC PROTEINS; SCRAPIE;

EID: 84901591151     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.04.069     Document Type: Article

References (27)

1. A. Aguzzi, and C. Weissmann Prion research: the next frontiers Nature 389 1997 795 798
2. D.C. Bolton, M.P. McKinley, and S.B. Prusiner Identification of a protein that purifies with the scrapie prion Science 218 1982 1309 1311
3. R.H. Kimberlin, and C. Walker Characteristics of a short incubation model of scrapie in the golden hamster J. Gen. Virol. 34 1977 295 304
4. R.L. Chandler, and B.A. Turfrey Inoculation of voles, Chinese hamsters, gerbils and guinea-pigs with scrapie brain material Res. Vet. Sci. 13 1972 219 224
5. R.I. Carp, X. Ye, R.J. Kascsak, and R. Rubenstein The nature of the scrapie agent. Biological characteristics of scrapie in different scrapie strain-host combinations Ann. N. Y. Acad. Sci. 724 1994 221 234
6. P.J. Lucassen, A. Williams, W.C. Chung, and H. Fraser Detection of apoptosis in murine scrapie Neurosci. Lett. 198 1995 185 188
7. B. Su, X. Wang, L. Zheng, G. Perry, M.A. Smith, and X. Zhu Abnormal mitochondrial dynamics and neurodegenerative diseases Biochim. Biophys. Acta 2010 1802 135 142
8. M.T. Lin, and M.F. Beal Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 2006 787 795
9. H. Chen, and D.C. Chan Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases Hum. Mol. Genet. 18 2009 R169 R176
10. X. Wang, B. Su, S.L. Siedlak, P.I. Moreira, H. Fujioka, Y. Wang, G. Casadesus, and X. Zhu Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins Proc. Natl. Acad. Sci. U.S.A. 105 2008 19318 19323
11. H. Deng, M.W. Dodson, H. Huang, and M. Guo The Parkinson's disease genes pink1 and Parkin promote mitochondrial fission and/or inhibit fusion in Drosophila Proc. Natl. Acad. Sci. U.S.A. 105 2008 14503 14508 2
12. T. Milakovic, and G.V. Johnson Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin J. Biol. Chem. 280 2005 30773 30782
13. A.V. Panov, C.A. Gutekunst, B.R. Leavitt, M.R. Hayden, J.R. Burke, W.J. Strittmatter, and J.T. Greenamyre Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines Nat. Neurosci. 5 2002 731 736
14. F. Squitieri, M. Cannella, G. Sgarbi, V. Maglione, A. Falleni, P. Lenzi, A. Baracca, G. Cislaghi, C. Saft, G. Ragona, M.A. Russo, L.M. Thompson, G. Solaini, and F. Fornai Severe ultrastructural mitochondrial changes in lymphoblasts homozygous for Huntington disease mutation Mech. Ageing Dev. 127 2006 217 220
15. S.I. Choi, W.K. Ju, E.K. Choi, J. Kim, H.Z. Lea, R.I. Carp, H.M. Wisniewski, and Y.S. Kim Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent Acta Neuropathol. 96 1998 279 286
16. J.H. Park, B.H. Kim, S.J. Park, J.K. Jin, Y.C. Jeon, G.Y. Wen, H.Y. Shin, R.I. Carp, and Y.S. Kim Association of endothelial nitric oxide synthase and mitochondrial dysfunction in the hippocampus of scrapie-infected mice Hippocampus 21 2010 319 333
17. J.K. Choi, S.J. Park, Y.C. Jun, J.M. Oh, B.H. Jeong, H.P. Lee, S.N. Park, R.I. Carp, and Y.S. Kim Generation of monoclonal antibody recognized by the GXXXG motif (glycine zipper) of prion protein Hybridoma (Larchmt) 25 2006 271 277
18. W.K. Ju, K.J. Park, E.K. Choi, J. Kim, R.I. Carp, H.M. Wisniewski, and Y.S. Kim Expression of inducible nitric oxide synthase in the brains of scrapie-infected mice J. Neurovirol. 4 1998 445 450
19. S. Frank Dysregulation of mitochondrial fusion and fission: an emerging concept in neurodegeneration Acta Neuropathol. 111 2006 93 100
20. D.C. Chan Mitochondrial fusion and fission in mammals Annu. Rev. Cell Dev. Biol. 22 2006 79 99
21. A. Sante, and M.T. Fuller Control of mitochondrial morphology by a human mitofusin J. Cell Sci. 114 2001 867 874
22. S.A. Detmer, and D.C. Chan Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations J. Cell Biol. 176 2007 405 414
23. R.M. Deacon, D. Reisel, V.H. Perry, J. Nicholas, and P. Rawlins Hippocampal scrapie infection impairs operant DRL performance in mice Behav. Brain Res. 157 2005 99 105
24. Y. Yoon, E.W. Krueger, B.J. Oswald, and M.A. McNiven The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1 Mol. Cell. Biol. 23 2003 5409 5420
25. Z. Sisková, D.J. Mahad, C. Pudney, G. Campbell, M. Cadogan, A. Asuni, V. O'Connor, and V.H. Perry Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease Am. J. Pathol. 177 2010 1411 1421
26. X. Wang, B. Su, H.G. Lee, X. Li, G. Perry, M.A. Smith, and X. Zhu Impaired balance of mitochondrial fission and fusion in Alzheimer's disease J. Neurosci. 29 2009 9090 9103
27. S. Frank, B. Gaume, E.S. Bergmann-Leitner, W.W. Leitner, E.G. Robert, F. Catez, C.L. Smith, and R.J. Youle The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis Dev. Cell 1 2001 515 525