CpG oligodeoxynucleotide-enhanced humoral immune response and production of antibodies to prion protein PrPSc in mice immunized with 139A scrapie-associated fibrils

Journal of Leukocyte Biology

Volumn 81, Issue 6, 2007, Pages 1374-1385

  Spinner, Daryl S ^a   Kascsak, Regina B ^a   LaFauci, Giuseppe ^a   Meeker, Harry C ^a   Ye, Xuemin ^a,c   Flory, Michael J ^a   Kim, Jae Il ^a,d   Schuller Levis, Georgia B ^a   Levis, William R ^b   Wisniewski, Thomas ^b   Carp, Richard I ^a   Kascsak, Richard J ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Innate immunity; Monoclonal antibodies; Toll like receptor 9 (TLR9 or TLR 9); Transmissible spongiform encephalopathy (TSE)

Indexed keywords

6D11 MONOCLONAL ANTIBODY; AMINO ACID; CPG OLIGODEOXYNUCLEOTIDE; CPG OLIGODEOXYNUCLEOTIDE 1826; EPITOPE; GLUTAMINYLTRYPTOPHYLASPARAGINYLLYSINE; MONOCLONAL ANTIBODY; PRION PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCRAPIE; TITRIMETRY; WILD TYPE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; DNA; EPITOPES; IMMUNITY, NATURAL; IMMUNIZATION; IMMUNOGLOBULIN CLASS SWITCHING; MICE; MICE, KNOCKOUT; PRP 27-30 PROTEIN; PRPSC PROTEINS; TH1 CELLS; TH2 CELLS; TOLL-LIKE RECEPTOR 9;

MUS;

EID: 34249690678     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1106665     Document Type: Article

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