Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease

Free Radical Biology and Medicine

Volumn 45, Issue 8, 2008, Pages 1159-1166

  Pamplona, Reinald ^a   Naudí, Alba ^a   Gavín, Rosalina ^b   Pastrana, Miguel A ^c   Sajnani, Gustavo ^c   Ilieva, Ekaterina V ^a   del Río, José Antonio ^b   Portero Otín, Manuel ^a   Ferrer, Isidre ^d   Requena, Jesús R ^c  

^a UNIVERSITY OF LLEIDA   (Spain)

^b INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

Aminoadipic semialdehyde; Carboxyethyllysine; Carboxymethyllysine; Glutamic semialdehyde; Malondialdehydelysine; Mass spectrometry; Prion disease; Protein oxidation

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ALDEHYDE DERIVATIVE; AMINOADIPIC ACID; AMINOADIPIC SEMIALDEHYDE; BRAIN PROTEIN; DIAMINO ACID; GLUTAMIC ACID; GLUTAMIC SEMIALDEHYDE; MALONDIALDEHYDELYSINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N EPSILON CARBOXYETHYLLYSINE; PRION PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATAXIA; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; FEMALE; GLYCOXIDATION; HUMAN; HUMAN TISSUE; LIPID COMPOSITION; LIPOXIDATION; MALE; MASS SPECTROMETRY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SCRAPIE;

AGED; AGED, 80 AND OVER; ANIMALS; BRAIN; BRAIN CHEMISTRY; CRICETINAE; FATTY ACIDS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; LIPID PEROXIDATION; MALE; MESOCRICETUS; MIDDLE AGED; OXIDATION-REDUCTION; OXIDATIVE STRESS; PRION DISEASES;

MESOCRICETUS AURATUS;

EID: 53249095492     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.07.009     Document Type: Article

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