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Volumn 106, Issue , 2015, Pages 167-179

Multicomponent assembly of 4-aza-podophyllotoxins: A fast entry to highly selective and potent anti-leukemic agents

Author keywords

AML; Anti leukemic agents; Aza podophyllotoxins; Etoposide; Multicomponent reactions; SAR study

Indexed keywords

10 (3,4,5-TRIMETHOXYPHENYL) 3,6,7,8 TETRAHYDRO 1H CYCLOPENTA[G]FURO[3,4 B]QUINOL; 10 (PERFLUOROPHENYL) 3,4,6,7,8,10 HEXAHYDRO 1H CYCLOPENTA[G]FURO[3,4 B]QUINOLIN 1 ONE; 10 HENYL 3,4,6,7,8,10 HEXAHYDRO 1H CYCLOPENTA[G]FURO[3,4B]QUINOLIN 1 ONE; 11 (3,4,5 TRIMETHOXYPHENYL) 4,6,7,8,9,11 HEXAHYDROBENZO[G] FURO[3,4 B]QUINOLIN 1(3H)ONE; 11 (3,4,5 TRIMETHOXYPHENYL) 6,7,8,9 TETRAHYDROBENZO[G]FURO [3,4 B]QUINOLIN 1(3H)ONE; 11 (PERFLUOROPHENYL) 4,6,7,8,9,11 HEXAHYDROBENZO[G]FURO[3,4 B]QUINOLIN 1(3H)ONE; 11 PHENYL 4,6,7,8,9,11 HEXAHYDROBENZO[G]FURO[3,4 B]QUINOLIN 1(3H)ONE; 5 (METHYLTHIO) 9 (3,4,5 TRIMETHOXYPHENYL) 4,9 DIHYDROFURO [3,4 B]QUINOLIN 1(3H)ONE; 6 (DIFLUOROMETHOXY) 9 (3,4,5 TRIMETHOXYPHENYL) 4,9 DIHYDROFURO[3,4 B]QUINOLIN 1(3H)ONE; 6 (DIFLUOROMETHOXY) 9 (PERFLUOROPHENYL) 4,9 DIHYDROFURO[3,4 B]QUINOLIN 1(3H)ONE; 6 (DIFLUOROMETHOXY) 9 PHENYL 4,9 DIHYDROFURO[3,4 B]QUINOLIN 1(3H)ONE; 6 (METHYLTHIO) 9 (3,4,5 TRIMETHOXYPHENYL) 4,9 DIHYDROFURO [3,4 B]QUINOLIN 1(3H)ONE; 6 (METHYLTHIO) 9 (PERFLUOROPHENYL) 4,9 DIHYDROFURO[3,4 B] QUINOLIN 1(3H)ONE; 6 HYDROXY 9 (4 HYDROXY 3 METHOXYPHENYL) 4,9 DIHYDROFURO[3,4 B]QUINOLIN 1(3H)ONE; 7 (3,4,5 TRIMETHOXYPHENYL) 7,11 DIHYDROBENZO[H]FURO[3,4 B] QUINOLIN 8(10H)ONE; 7 (BENZO[D][1,3]DIOXOL 5 YL) 8 OXO 7,8,10,11 TETRAHYDROBENZO[H]FURO[3,4 B]QUINOLINE 5 CARBONITRILE; 7 (PERFLUOROPHENYL) 7,11 DIHYDROBENZO[H]FURO[3,4 B]QUINOLIN 8(10H)ONE; 8 OXO 7 (3,4,5 TRIMETHOXYPHENYL) 7,8,10,11 TETRAHYDROBENZO[H]FURO[3,4 B]QUINOLINE 5 CARBONITRILE; 8 OXO 7 (PERFLUOROPHENYL) 7,8,10,11 TETRAHYDROBENZO[H]FURO [3,4 B]QUINOLINE 5 CARBONITRILE; 9 (2,3 DIMETHOXYPHENYL) 6 (METHYLTHIO) 4,9 DIHYDROFURO [3,4 B]QUINOLIN 1(3H)ONE; 9 (4 FLUOROPHENYL) 6 (METHYLTHIO) 4,9 DIHYDROFURO[3,4 B] QUINOLIN 1(3H)ONE; 9 (4 HYDROXY 3-METHOXYPHENYL) 5 (METHYLTHIO) 4,9 DIHYDROFURO[3,4 B]QUINOLIN 1(3H)ONE; 9 (4 METHOXYPHENYL) 6,9 DIHYDRO [1,3]DIOXOLO[4,5 G]FURO [3,4 B]QUINOLIN 8(5H)ONE; 9 (BENZO[D][1,3]DIOXOL 5 YL) 6 (DIFLUOROMETHOXY) 4,9 DIHYDROFURO[3,4 B]QUINOLIN 1(3H)ONE; 9 (BENZO[D][1,3]DIOXOL 5 YL) 6,9 DIHYDRO [1,3]DIOXOLO[4,5 G]FURO[3,4 B]QUINOLIN 8(5H)ONE; 9 (PERFLUOROPHENYL) 6,9 DIHYDRO [1,3]DIOXOLO[4,5 G]FURO[3,4 B]QUINOLIN 8(5H)ONE; ANTILEUKEMIC AGENT; ETOPOSIDE; PODOPHYLLOTOXIN DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTINEOPLASTIC AGENT; PODOPHYLLOTOXIN; TRYPAN BLUE;

EID: 84946573781     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.10.009     Document Type: Article
Times cited : (20)

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