Design and effective synthesis of the first 4-aza-2,3- didehydropodophyllotoxin rigid aminologue: A N-methyl-4-[(3,4,5- trimethoxyphenyl)amino]-1,2-dihydroquinoline-lactone

Journal of Organic Chemistry

Volumn 73, Issue 9, 2008, Pages 3642-3645

  Labruère, Raphaël ^a   Helissey, Philippe ^a   Desbène Finck, Stéphanie ^a   Giorgi Renault, Sylviane ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL); TOXIC MATERIALS;

LACTONES; STARTING MATERIALS; SYNTHETIC PATHWAYS;

ESTERS;

ALPHA TUBULIN; AMINO ACID DERIVATIVE; BETA TUBULIN; CANATOXIN; COLCHICINE DERIVATIVE; PODOPHYLLOTOXIN DERIVATIVE; QUINOLINOL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLOADDITION; HYDROGENATION; ISOMERIZATION; MICHAEL ADDITION; NUCLEAR MAGNETIC RESONANCE; ONE POT SYNTHESIS; OXIDATION; REACTION ANALYSIS; REDUCTION; STEREOCHEMISTRY; SUBSTITUTION REACTION; X RAY;

AMINATION; AZA COMPOUNDS; CATALYSIS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HYDROGEN; LACTONES; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PODOPHYLLOTOXIN;

EID: 43449103353     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo800166b     Document Type: Article

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