Histone deacetylase inhibitors synergistically potentiate death receptor 4-mediated apoptotic cell death of human T-cell acute lymphoblastic leukemia cells

Apoptosis

Volumn 15, Issue 10, 2010, Pages 1256-1269

  Sung, Eun Sil ^a   Kim, Aeyung ^a   Park, Joon Seong ^b   Chung, Junho ^c   Kwon, Myung Hee ^b   Kim, Yong Sung ^a  

^a Ajou University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

Agonistic antibody; Apoptosis; Death receptor 4; Histone deacetylase inhibitor; TRAIL

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE; CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DOXORUBICIN; ETOPOSIDE; FLICE INHIBITORY PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY AY4; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SN 50; SURVIVIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; VALPROIC ACID; VORINOSTAT; X LINKED INHIBITOR OF APOPTOSIS;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; DOWN-REGULATION; DRUG SYNERGISM; FLOW CYTOMETRY; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; INHIBITOR OF APOPTOSIS PROTEINS; MITOCHONDRIA; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND; VALPROIC ACID;

EID: 78650058230     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-010-0521-9     Document Type: Article

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