Interaction of the P-Glycoprotein Multidrug Transporter with Sterols

Biochemistry

Volumn 54, Issue 43, 2015, Pages 6586-6597

  Clay, Adam T ^a   Lu, Peihua ^a   Sharom, Frances J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING ENERGY; CHOLESTEROL; ENERGY TRANSFER; FLUORESCENCE QUENCHING; GLYCOPROTEINS; LIPID BILAYERS; PHOSPHOLIPIDS;

BINDING AFFINITIES; COLLISIONAL QUENCHING; FLUORESCENCE EMISSION; FLUORESCENCE STUDIES; FUNCTIONAL INTERACTION; MULTIDRUG RESISTANCE; MULTIDRUG TRANSPORTERS; TRANS-MEMBRANE DOMAINS;

ALCOHOLS;

ADENOSINE TRIPHOSPHATASE; CHOLESTEROL; CHOLESTEROL HYDROGEN SUCCINATE; DETERGENT; MULTIDRUG RESISTANCE PROTEIN; PROTEOLIPOSOME; STEROL; 4 CHLORO 7 NITROBENZOFURAZAN; 7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YLCHOLESTEROL; ABCB1B PROTEIN, MOUSE; CHOLESTEROL ESTER; CHOLESTERYL SUCCINATE; FLUORESCENT DYE; LIPID BILAYER; SOLUTION AND SOLUBILITY;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG TRANSPORT; ENZYME ACTIVITY; FLUORESCENCE ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN STABILITY; PROTEIN UNFOLDING; THERMAL ANALYSIS; ANALOGS AND DERIVATIVES; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; LIPID BILAYER; METABOLISM; MOUSE; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; SOLUTION AND SOLUBILITY; SPECTROFLUOROMETRY;

4-CHLORO-7-NITROBENZOFURAZAN; ANIMALS; BINDING SITES; CHOLESTEROL; CHOLESTEROL ESTERS; FLUORESCENT DYES; KINETICS; LIPID BILAYERS; MICE; MODELS, MOLECULAR; P-GLYCOPROTEINS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; STEROLS;

EID: 84946434311     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00904     Document Type: Article

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