The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence

European Biophysics Journal

Volumn 30, Issue 6, 2001, Pages 430-442

  Rothnie, A ^a   Theron, D ^a   Soceneantu, L ^a   Martin, C ^a   Traikia, M ^a   Berridge, G ^a   Higgins, C F ^a   Devaux, P F ^a   Callaghan, R ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cholesterol; Membrane biophysics; Multidrug resistance; P glycoprotein; Reconstitution

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CHOLESTEROL; DETERGENT; GLYCOPROTEIN P; LIPID; LIPOSOME; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; PROTEIN; VERAPAMIL;

ADSORPTION; ANIMAL CELL; ARTICLE; BIOPHYSICS; CONTROLLED STUDY; DOSE RESPONSE; DRUG PENETRATION; DRUG POTENCY; DRUG TRANSPORT; ENZYME ACTIVITY; HYDROLYSIS; LIPID BILAYER; MEMBRANE COMPONENT; MEMBRANE FLUIDITY; MEMBRANE PERMEABILITY; MEMBRANE RECONSTITUTION; MEMBRANE STABILIZATION; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PROTEOLIPOSOME; TUMOR CELL;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM CHANNEL BLOCKERS; CELL LINE; CELL MEMBRANE; CENTRIFUGATION, DENSITY GRADIENT; CHICKENS; CHOLESTEROL; CRICETINAE; DETERGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGGS; HYDROLYSIS; KINETICS; LIPID BILAYERS; LIPIDS; LIPOSOMES; P-GLYCOPROTEIN; PHOSPHOLIPIDS; PROTEIN STRUCTURE, TERTIARY; PROTEOLIPIDS; SUCROSE; VERAPAMIL;

ANIMALIA;

EID: 0034778472     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002490100156     Document Type: Article

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