Drug transport by reconstituted P-glycoprotein in proteoliposomes: Effect of substrates and modulators, and dependence on bilayer phase state

European Journal of Biochemistry

Volumn 268, Issue 6, 2001, Pages 1687-1697

  Lu, Peihua ^a   Liu, Ronghua ^a   Sharom, Frances J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Fluorescence; Multidrug resistance; Phase transition; Phospholipid bilayer; Tetramethylrosamine

Indexed keywords

ADENOSINE TRIPHOSPHATASE INHIBITOR; ADENOSINE TRIPHOSPHATE; COLCHICINE; CYCLOSPORIN A; FLUORESCENT DYE; GLYCOPROTEIN P; PHOSPHATIDYLCHOLINE; TETRAMETHYLROSAMINE; UNCLASSIFIED DRUG; VANADIC ACID; VERAPAMIL;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHO CELL; CONTROLLED STUDY; DRUG BINDING SITE; DRUG TRANSPORT; FLUORESCENCE; HYDROLYSIS; LIPID BILAYER; LIQUID CRYSTAL; MELTING POINT; MICHAELIS MENTEN KINETICS; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; PROTEOLIPOSOME; TEMPERATURE DEPENDENCE;

ANIMALS; BIOLOGICAL TRANSPORT; CHO CELLS; CRICETINAE; LIPID BILAYERS; P-GLYCOPROTEIN; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PROTEOLIPIDS;

EID: 0034818922     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02041.x     Document Type: Article

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