Characterization of fluorescent sterol binding to purified human NPC1

Journal of Biological Chemistry

Volumn 284, Issue 3, 2009, Pages 1840-1852

  Liu, Ronghua ^a   Lu, Peihua ^a   Chu, Joseph W K ^a   Sharom, Frances J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; ALCOHOLS; AMINES; ANIMAL CELL CULTURE; BINDING ENERGY; BINDING SITES; CELL PROLIFERATION; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DETERGENTS; ENZYME ACTIVITY; FILTRATION; FLUORESCENCE; GELATION; LIPIDS; LIQUID CHROMATOGRAPHY; POROUS MATERIALS; PURIFICATION; QUENCHING; STOICHIOMETRY;

AQUEOUS MEDIUMS; BINDING AFFINITIES; CELLULAR FUNCTIONS; CHINESE HAMSTER OVARY CELLS; CONCENTRATION DEPENDENTS; DEHYDROERGOSTEROL; DETERGENT CONCENTRATIONS; DETERGENT SOLUTIONS; DYNAMIC QUENCHING; ENHANCED FLUORESCENCES; FAST PROTEIN LIQUID CHROMATOGRAPHIES; GEL FILTRATIONS; HYDROPHOBIC POCKETS; INTRACELLULAR CHOLESTEROLS; MOLECULAR PROPERTIES; NIEMANN-PICK TYPE C; NOVEL INFORMATIONS; RESISTANCE-NODULATION-CELL DIVISIONS; STEROL-SENSING; TRP FLUORESCENCES;

CHOLESTEROL;

22 (N (7 NITROBENZ 2 OXA 1,3 DIAZOL 4 YL)AMINO) 23,24 BISNOR 5 CHOLEN 3BETA OL; 25 HYDROXYCHOLESTEROL; 3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; AZIDE; CHOLESTATRIENOL; CHOLESTEROL DERIVATIVE; DEHYDROERGOSTEROL; DETERGENT; NPC1 PROTEIN; OLIGOMER; PERMEASE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CHO CELL; CONTROLLED STUDY; ENZYME PURIFICATION; FAST PROTEIN LIQUID CHROMATOGRAPHY; FLUORESCENCE; GEL FILTRATION; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; SOLUBILIZATION; STOICHIOMETRY;

4-CHLORO-7-NITROBENZOFURAZAN; ANIMALS; BINDING SITES; CARRIER PROTEINS; CHO CELLS; CHOLESTEROL; CHOLIC ACIDS; CRICETINAE; CRICETULUS; FLUORESCENT DYES; HUMANS; HYDROXYCHOLESTEROLS; MEMBRANE GLYCOPROTEINS; NIEMANN-PICK DISEASES; PROTEIN BINDING; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS;

EID: 59449095489     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803741200     Document Type: Article

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