Inhibition of human α-amylase by dietary polyphenols

Journal of Functional Foods

Volumn 19, Issue , 2015, Pages 723-732

  Nyambe Silavwe, Hilda ^a   Villa Rodriguez, Jose A ^a   Ifie, Idolo ^a   Holmes, Melvin ^a   Aydin, Ebru ^a   Jensen, Jane Møller ^a   Williamson, Gary ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Amylopectin; Amylose; Diabetes; Polyphenol; Amylase

Indexed keywords

EID: 84946404054     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2015.10.003     Document Type: Article

References (36)

1. Acker M.G., Auld D.S. Considerations for the design and reporting of enzyme assays in high-throughput screening applications. Perspectives in Science 2014, 1(1-6):56-73. 10.1016/j.pisc.2013.12.001.
2. Ahmed D., Kumar V., Sharma M., Verma A. Target guided isolation, in-vitro antidiabetic, antioxidant activity and molecular docking studies of some flavonoids from Albizzia Lebbeck Benth. bark. BMC Complementary and Alternative Medicine 2014, 14. 10.1186/1472-6882-14-155.
3. Akkarachiyasit S., Charoenlertkul P., Yibchok-anun S., Adisakwattana S. Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal alpha-glucosidase and pancreatic alpha-amylase. International Journal of Molecular Sciences 2010, 11(9):3387-3396. 10.3390/ijms11093387.
4. Akkarachiyasit S., Yibchok-Anun S., Wacharasindhu S., Adisakwattana S. In vitro inhibitory effects of cyandin-3-rutinoside on pancreatic alpha-amylase and its combined effect with acarbose. Molecules 2011, 16(3):2075-2083. 10.3390/molecules16032075.
5. Ali R.B., Atangwho I.J., Kuar N., Ahmad M., Mahmud R., Asmawi M.Z. In vitro and in vivo effects of standardized extract and fractions of Phaleria macrocarpa fruits pericarp on lead carbohydrate digesting enzymes. BMC Complementary and Alternative Medicine 2013, 13. 10.1186/1472-6882-13-39.
6. Barrett A., Ndou T., Hughey C.A., Straut C., Howell A., Dai Z., Kaletunc G. Inhibition of alpha-amylase and glucoamylase by tannins extracted from cocoa, pomegranates, cranberries, and grapes. Journal of Agricultural and Food Chemistry 2013, 61(7):1477-1486. 10.1021/jf304876g.
7. Brayer G.D., Luo Y., Withers S.G. The structure of human pancreatic α-amylase at 1.8 Å resolution and comparisons with related enzymes. Protein Science 1995, 4(9):1730-1742.
8. Chen L., Kang Y.-H. In vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of red pepper (capsicum annuum l.) including pericarp, placenta, and stalk. Journal of Food Biochemistry 2014, 38(3):300-306. 10.1111/jfbc.12048.
9. Danaei G., Finucane M., Lu Y., Singh G., Cowan M., Paciorek C., Stevens G. Global burden of metabolic risk factors of chronic diseases collaborating group (blood glucose) national, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: Systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 2011, 378(9785):31-40.
10. Dixon M. The determination of enzyme inhibitor constants. Biochemical Journal 1953, 55(1):170.
11. Forester S.C., Gu Y., Lambert J.D. Inhibition of starch digestion by the green tea polyphenol, (-)-epigallocatechin-3-gallate. Molecular Nutrition & Food Research 2012, 56(11):1647-1654. 10.1002/mnfr.201200206.
12. Grussu D., Stewart D., McDougall G.J. Berry polyphenols inhibit alpha-amylase in vitro: Identifying active components in rowanberry and raspberry. Journal of Agricultural and Food Chemistry 2011, 59(6):2324-2331. 10.1021/jf1045359.
13. Hanhineva K., Torronen R., Bondia-Pons I., Pekkinen J., Kolehmainen M., Mykkanan H., Poutanen K. Impact of dietary polyphenols on carbohydrate metabolism. International Journal of Molecular Sciences 2010, 11(4):1365-1402. 10.3390/ijms11041365.
14. Hossain S.J., Tsujiyama I., Takasugi M., Islam M.A., Biswas R.S., Aoshima H. Total phenolic content, antioxidative, anti-amylase, anti-glucosidase, and antihistamine release activities of Bangladeshi fruits. Food Science and Technology Research 2008, 14(3):261-268. 10.3136/fstr.14.261.
15. Iwai K., Kim M.Y., Onodera A., Matsue H. Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of Viburnum dilatatum Thunb. Journal of Agricultural and Food Chemistry 2006, 54(13):4588-4592. 10.1021/jf0606353.
16. Kim J.S., Kwon C.S., Son K.H. Inhibition of alpha-glucosidase and amylase by luteolin, a flavonoid. Bioscience, Biotechnology, and Biochemistry 2000, 64(11):2458-2461. 10.1271/bbb.64.2458.
17. Kim Y.M., Jeong Y.K., Wang M.H., Lee W.Y., Rhee H.I. Inhibitory effect of pine extract on alpha-glucosidase activity and postprandial hyperglycemia. Nutrition (Burbank, Los Angeles County, Calif.) 2005, 21(6):756-761. 10.1016/j.nut.2004.10.014.
18. Koh L.W., Wong L.L., Loo Y.Y., Kasapis S., Huang D. Evaluation of different teas against starch digestibility by mammalian glycosidases. Journal of Agricultural and Food Chemistry 2010, 58(1):148-154. 10.1021/jf903011g.
19. Lee Y.A., Cho E.J., Tanaka T., Yokozawa T. Inhibitory activities of proanthocyanidins from persimmon against oxidative stress and digestive enzymes related to diabetes. Journal of Nutritional Science and Vitaminology 2007, 53(3):287-292. 10.3177/jnsv.53.287.
20. Livesey G., Taylor R., Hulshof T., Howlett J. Glycemic response and health - A systematic review and meta-analysis: Relations between dietary glycemic properties and health outcomes. The American Journal of Clinical Nutrition 2008, 87(1):258S-268S.
21. Lo Piparo E., Scheib H., Frei N., Williamson G., Grigorov M., Chou C.J. Flavonoids for controlling starch digestion: Structural requirements for inhibiting human alpha-amylase. Journal of Medicinal Chemistry 2008, 51(12):3555-3561. 10.1021/jm800115x.
22. Manzano S., Williamson G. Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells. Molecular Nutrition & Food Research 2010, 54(12):1773-1780.
23. McDougall G.J., Shpiro F., Dobson P., Smith P., Blake A., Stewart D. Different polyphenolic components of soft fruits inhibit alpha-amylase and alpha-glucosidase. Journal of Agricultural and Food Chemistry 2005, 53(7):2760-2766. 10.1021/jf0489926.
24. Miao M., Jiang H., Jiang B., Li Y., Cui S.W., Zhang T. Structure elucidation of catechins for modulation of starch digestion. LWT-Food Science and Technology 2014, 57(1):188-193. 10.1016/j.lwt.2014.01.005.
25. Oboh G., Ademiluyi A.O., Akinyemi A.J., Henle T., Saliu J.A., Schwarzenbolz U. Inhibitory effect of polyphenol-rich extracts of jute leaf (Corchorus olitorius) on key enzyme linked to type 2 diabetes (alpha-amylase and alpha-glucosidase) and hypertension (angiotensin I converting) in vitro. Journal of Functional Foods 2012, 4(2):450-458. 10.1016/j.jff.2012.02.003.
26. Rice-Evans C.A., Miller N.J., Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology and Medicine 1996, 20(7):933-956.
27. Roy M.-C., Anguenot R., Fillion C., Beaulieu M., Berube J., Richard D. Effect of a commercially-available algal phlorotannins extract on digestive enzymes and carbohydrate absorption in vivo. Food Research International 2011, 44(9):3026-3029. 10.1016/j.foodres.2011.07.023.
28. Scheepers A., Joost H.-G., Schurmann A. The glucose transporter families SGLT and GLUT: Molecular basis of normal and aberrant function. Journal of Parenteral and Enteral Nutrition 2004, 28(5):364-371.
29. Subramanian R., Asmawi M.Z., Sadikun A. In vitro alpha-glucosidase and alpha-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide. Acta Biochimica Polonica 2008, 55(2):391-398.
30. Tadera K., Minami Y., Takamatsu K., Matsuoka T. Inhibition of alpha-glucosidase and alpha-amylase by flavonoids. Journal of Nutritional Science and Vitaminology 2006, 52(2):149-153. 10.3177/jnsv.52.149.
31. Tsujita T., Shintani T., Sato H. Alpha-amylase inhibitory activity from nut seed skin polyphenols. 1. Purification and characterization of almond seed skin polyphenols. Journal of Agricultural and Food Chemistry 2013, 61(19):4570-4576. 10.1021/jf400691q.
32. Tsujita T., Takaku T., Suzuki T. Chestnut astringent skin extract, an. ALPHA.-amylase inhibitor, retards carbohydrate absorption in rats and humans. Journal of Nutritional Science and Vitaminology 2008, 54(1):82-88.
33. Tsujita T., Yamada M., Takaku T., Shintani T., Teramoto K., Sato T. Purification and characterization of polyphenols from chestnut astringent skin. Journal of Agricultural and Food Chemistry 2011, 59(16):8646-8654. 10.1021/jf201679q.
34. Williamson G. Possible effects of dietary polyphenols on sugar absorption and digestion. Molecular Nutrition & Food Research 2013, 57(1):48-57. 10.1002/mnfr.201200511.
35. Yilmazer-Musa M., Griffith A.M., Michels A.J., Schneider E., Frei B. Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of alpha-amylase and alpha-glucosidase activity. Journal of Agricultural and Food Chemistry 2012, 60(36):8924-8929. 10.1021/jf301147n.
36. Zhang L., Li J., Hogan S., Chung H., Welbaum G.E., Zhou K. Inhibitory effect of raspberries on starch digestive enzyme and their antioxidant properties and phenolic composition. Food Chemistry 2010, 119(2):592-599. 10.1016/j.foodchem.2009.06.063.