Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover

Physiological Genomics

Volumn 47, Issue 11, 2015, Pages 569-580

  Lynch, Christopher J ^a   Kimball, Scot R ^a   Xu, Yuping ^a   Salzberg, Anna C ^a   Kawasawa, Yuka Imamura ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Branched chain amino acids; Dystrophy; Eukaryotic initiation factor 2; Glycolysis; Integrin linked kinase; Leucine; MTOR; Myopathy; Protein degradation; Protein synthesis; Signaling; TCA cycle; ketoisocaproate

Indexed keywords

BRANCHED CHAIN AMINO ACID; BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE; INITIATION FACTOR 2; INTEGRIN LINKED KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE; RIBOSOME PROTEIN; TRANSCRIPTOME; UBIQUITIN; UNCLASSIFIED DRUG; AMINOTRANSFERASE; BCAT1 PROTEIN, MOUSE; MUSCLE PROTEIN;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BIOINFORMATICS; BODY SIZE; CARBOHYDRATE METABOLISM; CELL DEATH; CONTROLLED STUDY; FATTY ACID METABOLISM; GASTROCNEMIUS MUSCLE; GENE DELETION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE CELL; MUSCULAR DYSTROPHY; MYOPATHY; NEXT GENERATION SEQUENCING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; RNA SEQUENCE; UPREGULATION; ANIMAL; C57BL MOUSE; GENETICS; KNOCKOUT MOUSE; METABOLISM; SKELETAL MUSCLE;

ANIMALS; GENE DELETION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE PROTEINS; MUSCLE, SKELETAL; TRANSAMINASES;

EID: 84946037444     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00055.2015     Document Type: Article

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