메뉴 건너뛰기




Volumn 26, Issue 10, 2015, Pages 664-679

Preclinical assessment of mutant human TRIM5α as an Anti-HIV-1 transgene

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LENTIVIRUS VECTOR; TRANSCRIPTION FACTOR JUNB; TRIPARTITE MOTIF PROTEIN 5; TUMOR NECROSIS FACTOR ALPHA; CARRIER PROTEIN; MUTANT PROTEIN; PROTEIN BINDING; TRIM5 PROTEIN, HUMAN;

EID: 84945573328     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2015.059     Document Type: Article
Times cited : (21)

References (107)
  • 1
    • 78650735673 scopus 로고    scopus 로고
    • Human hematopoietic stem/progenitor cells modified by zincfinger nucleases targeted to CCR5 control HIV-1 in vivo
    • Holt N, Wang J, Kim K, et al. Human hematopoietic stem/progenitor cells modified by zincfinger nucleases targeted to CCR5 control HIV-1 in vivo. Nat Biotechnol 2010; 28: 839-847
    • (2010) Nat Biotechnol , vol.28 , pp. 839-847
    • Holt, N.1    Wang, J.2    Kim, K.3
  • 2
    • 84895487305 scopus 로고    scopus 로고
    • Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
    • Tebas P, Stein D, Tang WW, et al. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N Engl J Med 2014; 370: 901-910
    • (2014) N Engl J Med , vol.370 , pp. 901-910
    • Tebas, P.1    Stein, D.2    Tang, W.W.3
  • 3
    • 80755125618 scopus 로고    scopus 로고
    • Current progress and challenges in HIV gene therapy
    • Chung J, Rossi JJ, Jung U. Current progress and challenges in HIV gene therapy. Future Virol 2011; 6: 1319-1328
    • (2011) Future Virol , vol.6 , pp. 1319-1328
    • Chung, J.1    Rossi, J.J.2    Jung, U.3
  • 4
    • 77952572526 scopus 로고    scopus 로고
    • Frequent CXCR4 tropism of HIV-1 subtype a and CRF02-AG during late-stage disease-indication of an evolving epidemic in West Africa
    • Esbjornsson J, Mansson F, Martinez-Arias W, et al. Frequent CXCR4 tropism of HIV-1 subtype a and CRF02-AG during late-stage disease-indication of an evolving epidemic in West Africa. Retrovirology 2010; 7: 23
    • (2010) Retrovirology , vol.7 , pp. 23
    • Esbjornsson, J.1    Mansson, F.2    Martinez-Arias, W.3
  • 5
    • 1542288934 scopus 로고    scopus 로고
    • The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
    • Stremlau M, Owens CM, Perron MJ, et al. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004; 427: 848-853
    • (2004) Nature , vol.427 , pp. 848-853
    • Stremlau, M.1    Owens, C.M.2    Perron, M.J.3
  • 6
    • 0037213619 scopus 로고    scopus 로고
    • Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells
    • Owens CM, Yang PC, Gottlinger H, et al. Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells. J Virol 2003; 77: 726-731
    • (2003) J Virol , vol.77 , pp. 726-731
    • Owens, C.M.1    Yang, P.C.2    Gottlinger, H.3
  • 7
    • 0037015007 scopus 로고    scopus 로고
    • Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism
    • Cowan S, Hatziioannou T, Cunningham T, et al. Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism. Proc Natl Acad Sci USA 2002; 99: 11914-11919
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11914-11919
    • Cowan, S.1    Hatziioannou, T.2    Cunningham, T.3
  • 8
    • 11144229594 scopus 로고    scopus 로고
    • Structural requirements for recognition of the human immunodeficiency virus type 1 core during host restriction in owl monkey cells
    • Forshey BM, Shi J, Aiken C. Structural requirements for recognition of the human immunodeficiency virus type 1 core during host restriction in owl monkey cells. J Virol 2005; 79: 869-875
    • (2005) J Virol , vol.79 , pp. 869-875
    • Forshey, B.M.1    Shi, J.2    Aiken, C.3
  • 9
    • 6344228445 scopus 로고    scopus 로고
    • Influence of gag on human immunodeficiency virus type 1 species-specific tropism
    • Ikeda Y, Ylinen LM, Kahar-Bador M, et al. Influence of gag on human immunodeficiency virus type 1 species-specific tropism. J Virol 2004; 78: 11816-11822
    • (2004) J Virol , vol.78 , pp. 11816-11822
    • Ikeda, Y.1    Ylinen, L.M.2    Kahar-Bador, M.3
  • 10
    • 33745263205 scopus 로고    scopus 로고
    • Saturation of TRIM5 alpha-mediated restriction of HIV-1 infection depends on the stability of the incoming viral capsid
    • Shi J, Aiken C. Saturation of TRIM5 alpha-mediated restriction of HIV-1 infection depends on the stability of the incoming viral capsid. Virology 2006; 350: 493-500
    • (2006) Virology , vol.350 , pp. 493-500
    • Shi, J.1    Aiken, C.2
  • 11
    • 33645794537 scopus 로고    scopus 로고
    • Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor
    • Stremlau M, Perron M, Lee M, et al. Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. Proc Natl Acad Sci USA 2006; 103: 5514-5519
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5514-5519
    • Stremlau, M.1    Perron, M.2    Lee, M.3
  • 12
    • 29744450267 scopus 로고    scopus 로고
    • Restriction of human immunodeficiency virus type 1 by TRIM-CypA occurs with rapid kinetics and independently of cytoplasmic bodies, ubiquitin, and proteasome activity
    • Perez-Caballero D, Hatziioannou T, Zhang F, et al. Restriction of human immunodeficiency virus type 1 by TRIM-CypA occurs with rapid kinetics and independently of cytoplasmic bodies, ubiquitin, and proteasome activity. J Virol 2005; 79: 15567-15572
    • (2005) J Virol , vol.79 , pp. 15567-15572
    • Perez-Caballero, D.1    Hatziioannou, T.2    Zhang, F.3
  • 13
    • 39049147188 scopus 로고    scopus 로고
    • Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5alpha
    • Campbell EM, Perez O, Anderson JL, et al. Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5alpha. J Cell Biol 2008; 180: 549-561
    • (2008) J Cell Biol , vol.180 , pp. 549-561
    • Campbell, E.M.1    Perez, O.2    Anderson, J.L.3
  • 14
    • 77953297794 scopus 로고    scopus 로고
    • TRIM5alpha disrupts the structure of assembled HIV-1 capsid complexes in vitro
    • Black LR, Aiken C. TRIM5alpha disrupts the structure of assembled HIV-1 capsid complexes in vitro. J Virol 2010; 84: 6564-6569
    • (2010) J Virol , vol.84 , pp. 6564-6569
    • Black, L.R.1    Aiken, C.2
  • 15
    • 33847211051 scopus 로고    scopus 로고
    • The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-Tropic murine leukemia virus capsid
    • Perron MJ, Stremlau M, Lee M, et al. The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-Tropic murine leukemia virus capsid. J Virol 2007; 81: 2138-2148
    • (2007) J Virol , vol.81 , pp. 2138-2148
    • Perron, M.J.1    Stremlau, M.2    Lee, M.3
  • 16
    • 79953278280 scopus 로고    scopus 로고
    • Rhesus TRIM5a disrupts the HIV-1 capsid at the inter-hexamer interfaces
    • Zhao G, Ke D, Vu T, et al. Rhesus TRIM5a disrupts the HIV-1 capsid at the inter-hexamer interfaces. PLoS Pathog 2011; 7: e1002009
    • (2011) PLoS Pathog , vol.7 , pp. e1002009
    • Zhao, G.1    Ke, D.2    Vu, T.3
  • 17
    • 33748944362 scopus 로고    scopus 로고
    • Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins
    • Anderson JL, Campbell EM, Wu X, et al. Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins. J Virol 2006; 80: 9754-9760
    • (2006) J Virol , vol.80 , pp. 9754-9760
    • Anderson, J.L.1    Campbell, E.M.2    Wu, X.3
  • 18
    • 33744487449 scopus 로고    scopus 로고
    • Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5
    • Diaz-Griffero F, Li X, Javanbakht H, et al. Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5. Virology 2006; 349: 300-315
    • (2006) Virology , vol.349 , pp. 300-315
    • Diaz-Griffero, F.1    Li, X.2    Javanbakht, H.3
  • 19
    • 44949201552 scopus 로고    scopus 로고
    • Proteasomal degradation of TRIM5alpha during retrovirus restriction
    • Rold CJ, Aiken C. Proteasomal degradation of TRIM5alpha during retrovirus restriction. PLoS Pathog 2008; 4: e1000074
    • (2008) PLoS Pathog , vol.4 , pp. e1000074
    • Rold, C.J.1    Aiken, C.2
  • 20
    • 6344262057 scopus 로고    scopus 로고
    • Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA
    • Berthoux L, Sebastian S, Sokolskaja E, et al. Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA. J Virol 2004; 78: 11739-11750
    • (2004) J Virol , vol.78 , pp. 11739-11750
    • Berthoux, L.1    Sebastian, S.2    Sokolskaja, E.3
  • 21
    • 79955377543 scopus 로고    scopus 로고
    • TRIM5 is an innate immune sensor for the retrovirus capsid lattice
    • Pertel T, Hausmann S, Morger D, et al. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 2011; 472: 361-365
    • (2011) Nature , vol.472 , pp. 361-365
    • Pertel, T.1    Hausmann, S.2    Morger, D.3
  • 22
    • 79956120765 scopus 로고    scopus 로고
    • TRIM5 takes on pattern recognition
    • Tareen SU, Emerman M. TRIM5 takes on pattern recognition. Cell Host Microbe 2011; 9: 349-350
    • (2011) Cell Host Microbe , vol.9 , pp. 349-350
    • Tareen, S.U.1    Emerman, M.2
  • 23
    • 77954541463 scopus 로고    scopus 로고
    • Generation of human TRIM5alpha mutants with high HIV-1 restriction activity
    • Pham QT, Bouchard A, Grutter MG, et al. Generation of human TRIM5alpha mutants with high HIV-1 restriction activity. Gene Ther 2010; 17: 859-871
    • (2010) Gene Ther , vol.17 , pp. 859-871
    • Pham, Q.T.1    Bouchard, A.2    Grutter, M.G.3
  • 24
    • 3242720240 scopus 로고    scopus 로고
    • TRIM5alpha protein restricts both HIV-1 and murine leukemia virus
    • Yap MW, Nisole S, Lynch C, et al. TRIM5alpha protein restricts both HIV-1 and murine leukemia virus. Proc Natl Acad Sci USA 2004; 101: 10786-10791
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10786-10791
    • Yap, M.W.1    Nisole, S.2    Lynch, C.3
  • 25
    • 19944421408 scopus 로고    scopus 로고
    • Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues
    • Berthoux L, Sebastian S, Sayah DM, et al. Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues. J Virol 2005; 79: 7883-7888
    • (2005) J Virol , vol.79 , pp. 7883-7888
    • Berthoux, L.1    Sebastian, S.2    Sayah, D.M.3
  • 26
    • 25144460493 scopus 로고    scopus 로고
    • TRIM5alpha(rh) expression restricts HIV-1 infection in lentiviral vectortransduced CD34( + )-cell-derived macrophages
    • Anderson J, Akkina R. TRIM5alpha(rh) expression restricts HIV-1 infection in lentiviral vectortransduced CD34( + )-cell-derived macrophages. Mol Ther 2005; 12: 687-696
    • (2005) Mol Ther , vol.12 , pp. 687-696
    • Anderson, J.1    Akkina, R.2
  • 27
    • 79952191792 scopus 로고    scopus 로고
    • Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells
    • Kambal A, Mitchell G, Cary W, et al. Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells. Mol Ther 2011; 19: 584-593
    • (2011) Mol Ther , vol.19 , pp. 584-593
    • Kambal, A.1    Mitchell, G.2    Cary, W.3
  • 28
    • 11844278251 scopus 로고    scopus 로고
    • A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction
    • Yap MW, Nisole S, Stoye JP. A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction. Curr Biol 2005; 15: 73-78
    • (2005) Curr Biol , vol.15 , pp. 73-78
    • Yap, M.W.1    Nisole, S.2    Stoye, J.P.3
  • 29
    • 84876858334 scopus 로고    scopus 로고
    • A novel aminoacid determinant of HIV-1 restriction in the TRIM5a variable 1 region isolated in a random mutagenic screen
    • Pham QT, Veillette M, Brandariz-Nunez A, et al. A novel aminoacid determinant of HIV-1 restriction in the TRIM5a variable 1 region isolated in a random mutagenic screen. Virus Res 2013; 173: 306-314
    • (2013) Virus Res , vol.173 , pp. 306-314
    • Pham, Q.T.1    Veillette, M.2    Brandariz-Nunez, A.3
  • 30
    • 33745800238 scopus 로고    scopus 로고
    • Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection
    • Li Y, Li X, Stremlau M, et al. Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection. J Virol 2006; 80: 6738-6744
    • (2006) J Virol , vol.80 , pp. 6738-6744
    • Li, Y.1    Li, X.2    Stremlau, M.3
  • 31
    • 84874370905 scopus 로고    scopus 로고
    • The V86m mutation in HIV-1 capsid confers resistance to TRIM5a by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import
    • Veillette M, Bichel K, Pawlica P, et al. The V86m mutation in HIV-1 capsid confers resistance to TRIM5a by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import. Retrovirology 2013; 10: 25
    • (2013) Retrovirology , vol.10 , pp. 25
    • Veillette, M.1    Bichel, K.2    Pawlica, P.3
  • 32
    • 78650969008 scopus 로고    scopus 로고
    • Immune responses to transgene and retroviral vector in patients treated with ex vivo-engineered T cells
    • Lamers CH, Willemsen R, Van Elzakker P, et al. Immune responses to transgene and retroviral vector in patients treated with ex vivo-engineered T cells. Blood 2011; 117: 72-82
    • (2011) Blood , vol.117 , pp. 72-82
    • Lamers, C.H.1    Willemsen, R.2    Van Elzakker, P.3
  • 33
    • 0029936764 scopus 로고    scopus 로고
    • Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
    • Tripathy SK, Black HB, Goldwasser E, et al. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat Med 1996; 2: 545-550
    • (1996) Nat Med , vol.2 , pp. 545-550
    • Tripathy, S.K.1    Black, H.B.2    Goldwasser, E.3
  • 34
    • 84900448514 scopus 로고    scopus 로고
    • Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression
    • Yin Y, Takahashi Y, Ebisuura N, et al. Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression. J Gene Med 2014; 16: 97-106
    • (2014) J Gene Med , vol.16 , pp. 97-106
    • Yin, Y.1    Takahashi, Y.2    Ebisuura, N.3
  • 35
    • 84857959077 scopus 로고    scopus 로고
    • Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response
    • Troyer RM, Mcnevin J, Liu Y, et al. Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response. PLoS Pathog 2009; 5: e1000365
    • (2009) PLoS Pathog , vol.5 , pp. e1000365
    • Troyer, R.M.1    Mcnevin, J.2    Liu, Y.3
  • 36
    • 2342465557 scopus 로고    scopus 로고
    • Reversion of CTL escape-variant immunodeficiency viruses in vivo
    • Friedrich TC, Dodds EJ, Yant LJ, et al. Reversion of CTL escape-variant immunodeficiency viruses in vivo. Nat Med 2004; 10: 275-281
    • (2004) Nat Med , vol.10 , pp. 275-281
    • Friedrich, T.C.1    Dodds, E.J.2    Yant, L.J.3
  • 37
    • 36049027844 scopus 로고    scopus 로고
    • Evolution of human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitopes: Fitness-balanced escape
    • Liu Y, Mcnevin J, Zhao H, et al. Evolution of human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitopes: fitness-balanced escape. J Virol 2007; 81: 12179-12188
    • (2007) J Virol , vol.81 , pp. 12179-12188
    • Liu, Y.1    Mcnevin, J.2    Zhao, H.3
  • 38
    • 33645240933 scopus 로고    scopus 로고
    • Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
    • Martinez-Picado J, Prado JG, Fry EE, et al. Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol 2006; 80: 3617-3623
    • (2006) J Virol , vol.80 , pp. 3617-3623
    • Martinez-Picado, J.1    Prado, J.G.2    Fry, E.E.3
  • 39
    • 80655142502 scopus 로고    scopus 로고
    • Gag cytotoxic T lymphocyte escape mutations can increase sensitivity of HIV-1 to human TRIM5alpha, linking intrinsic and acquired immunity
    • Battivelli E, Migraine J, Lecossier D, et al. Gag cytotoxic T lymphocyte escape mutations can increase sensitivity of HIV-1 to human TRIM5alpha, linking intrinsic and acquired immunity. J Virol 2011; 85: 11846-11854
    • (2011) J Virol , vol.85 , pp. 11846-11854
    • Battivelli, E.1    Migraine, J.2    Lecossier, D.3
  • 40
    • 84883293598 scopus 로고    scopus 로고
    • Pressure from TRIM5a contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles
    • Granier C, Battivelli E, Lecuroux C, et al. Pressure from TRIM5a contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles. J Virol 2013; 87: 10368-10380
    • (2013) J Virol , vol.87 , pp. 10368-10380
    • Granier, C.1    Battivelli, E.2    Lecuroux, C.3
  • 41
    • 84898606389 scopus 로고    scopus 로고
    • The conserved sumoylation consensus site in TRIM5a modulates its immune activation functions
    • Nepveu-Traversy ME, Berthoux L. The conserved sumoylation consensus site in TRIM5a modulates its immune activation functions. Virus Res 2014; 184: 30-38
    • (2014) Virus Res , vol.184 , pp. 30-38
    • Nepveu-Traversy, M.E.1    Berthoux, L.2
  • 42
    • 78649442925 scopus 로고    scopus 로고
    • Human Trim5a has additional activities that are uncoupled from retroviral capsid recognition
    • Tareen SU, Emerman M. Human Trim5a has additional activities that are uncoupled from retroviral capsid recognition. Virology 2011; 409: 113-120
    • (2011) Virology , vol.409 , pp. 113-120
    • Tareen, S.U.1    Emerman, M.2
  • 43
    • 32444450679 scopus 로고    scopus 로고
    • Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner
    • Sebastian S, Sokolskaja E, Luban J. Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner. J Virol 2006; 80: 2051-2054
    • (2006) J Virol , vol.80 , pp. 2051-2054
    • Sebastian, S.1    Sokolskaja, E.2    Luban, J.3
  • 44
    • 0033199317 scopus 로고    scopus 로고
    • Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
    • Van Parijs L, Refaeli Y, Lord JD, et al. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 1999; 11: 281-288
    • (1999) Immunity , vol.11 , pp. 281-288
    • Van Parijs, L.1    Refaeli, Y.2    Lord, J.D.3
  • 45
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndromeassociated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi A, Gendelman HE, Koenig S, et al. Production of acquired immunodeficiency syndromeassociated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 1986; 59: 284-291
    • (1986) J Virol , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3
  • 46
    • 77957969218 scopus 로고    scopus 로고
    • Strain-specific differences in the impact of human TRIM5alpha, different TRIM5alpha alleles, and the inhibition of capsid-cyclophilin A interactions on the infectivity of HIV-1
    • Battivelli E, Lecossier D, Matsuoka S, et al. Strain-specific differences in the impact of human TRIM5alpha, different TRIM5alpha alleles, and the inhibition of capsid-cyclophilin A interactions on the infectivity of HIV-1. J Virol 2010; 84: 11010-11019
    • (2010) J Virol , vol.84 , pp. 11010-11019
    • Battivelli, E.1    Lecossier, D.2    Matsuoka, S.3
  • 47
    • 0034646513 scopus 로고    scopus 로고
    • HIV-1 genome nuclear import is mediated by a central DNA flap
    • Zennou V, Petit C, Guetard D, et al. HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 2000; 101: 173-185
    • (2000) Cell , vol.101 , pp. 173-185
    • Zennou, V.1    Petit, C.2    Guetard, D.3
  • 48
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey R, Nagy D, Mandel RJ, et al. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 1997; 15: 871-875
    • (1997) Nat Biotechnol , vol.15 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3
  • 49
    • 10744228940 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs
    • Li MJ, Bauer G, Michienzi A, et al. Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs. Mol Ther 2003; 8: 196-206
    • (2003) Mol Ther , vol.8 , pp. 196-206
    • Li, M.J.1    Bauer, G.2    Michienzi, A.3
  • 50
    • 33751113540 scopus 로고    scopus 로고
    • Design of expression vectors for RNA interference based on miRNAs and RNA splicing
    • Du G, Yonekubo J, Zeng Y, et al. Design of expression vectors for RNA interference based on miRNAs and RNA splicing. FEBS J 2006; 273: 5421-5427
    • (2006) FEBS J , vol.273 , pp. 5421-5427
    • Du, G.1    Yonekubo, J.2    Zeng, Y.3
  • 51
    • 0035005706 scopus 로고    scopus 로고
    • The cleavage activities of foot-And-mouth disease virus 2A site-directed mutants and naturally occurring 2A-like sequences
    • Donnelly ML, Hughes LE, Luke G, et al. The cleavage activities of foot-And-mouth disease virus 2A site-directed mutants and naturally occurring 2A-like sequences. J Gen Virol 2001; 82: 1027-1041
    • (2001) J Gen Virol , vol.82 , pp. 1027-1041
    • Donnelly, M.L.1    Hughes, L.E.2    Luke, G.3
  • 52
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
    • Wiznerowicz M, Trono D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J Virol 2003; 77: 8957-8961
    • (2003) J Virol , vol.77 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 53
    • 0032828730 scopus 로고    scopus 로고
    • A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor
    • Trkola A, Matthews J, Gordon C, et al. A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor. J Virol 1999; 73: 8966-8974
    • (1999) J Virol , vol.73 , pp. 8966-8974
    • Trkola, A.1    Matthews, J.2    Gordon, C.3
  • 54
    • 35948939711 scopus 로고    scopus 로고
    • Both TRIM5alpha and TRIMCyp have only weak antiviral activity in canine D17 cells
    • Bérubé J, Bouchard A, Berthoux L. Both TRIM5alpha and TRIMCyp have only weak antiviral activity in canine D17 cells. Retrovirology 2007; 4: 68
    • (2007) Retrovirology , vol.4 , pp. 68
    • Bérubé, J.1    Bouchard, A.2    Berthoux, L.3
  • 55
    • 0026562720 scopus 로고
    • Detection of replicationcompetent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene
    • Kimpton J, Emerman M. Detection of replicationcompetent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J Virol 1992; 66: 2232-2239
    • (1992) J Virol , vol.66 , pp. 2232-2239
    • Kimpton, J.1    Emerman, M.2
  • 56
    • 46349107250 scopus 로고    scopus 로고
    • The importance of and a method for including transfection efficiency into real-Time PCR data analyses
    • Godbey WT, Zhang X, Chang F. The importance of and a method for including transfection efficiency into real-Time PCR data analyses. Biotechnol Bioeng 2008; 100: 765-772
    • (2008) Biotechnol Bioeng , vol.100 , pp. 765-772
    • Godbey, W.T.1    Zhang, X.2    Chang, F.3
  • 57
    • 78149416617 scopus 로고    scopus 로고
    • Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5a
    • Pacheco B, Finzi A, Stremlau M, et al. Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5a. Virology 2010; 408: 204-212
    • (2010) Virology , vol.408 , pp. 204-212
    • Pacheco, B.1    Finzi, A.2    Stremlau, M.3
  • 58
    • 84884683244 scopus 로고    scopus 로고
    • Assisted evolution enables HIV-1 to overcome a high TRIM5a-imposed genetic barrier to rhesus macaque tropism
    • Soll SJ, Wilson SJ, Kutluay SB, et al. Assisted evolution enables HIV-1 to overcome a high TRIM5a-imposed genetic barrier to rhesus macaque tropism. PLoS Pathog 2013; 9: e1003667
    • (2013) PLoS Pathog , vol.9 , pp. e1003667
    • Soll, S.J.1    Wilson, S.J.2    Kutluay, S.B.3
  • 59
    • 0028195019 scopus 로고
    • Chemically selected subclones of the CEM cell line demonstrate resistance to HIV-1 infection resulting from a selective loss of NF-kappa B DNA binding proteins
    • Qian J, Bours V, Manischewitz J, et al. Chemically selected subclones of the CEM cell line demonstrate resistance to HIV-1 infection resulting from a selective loss of NF-kappa B DNA binding proteins. J Immunol 1994; 152: 4183-4191
    • (1994) J Immunol , vol.152 , pp. 4183-4191
    • Qian, J.1    Bours, V.2    Manischewitz, J.3
  • 60
    • 84871946152 scopus 로고    scopus 로고
    • TRIM proteinmediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity
    • Uchil PD, Hinz A, Siegel S, et al. TRIM proteinmediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol 2013; 87: 257-272
    • (2013) J Virol , vol.87 , pp. 257-272
    • Uchil, P.D.1    Hinz, A.2    Siegel, S.3
  • 61
    • 0033453239 scopus 로고    scopus 로고
    • Attenuation of green fluorescent protein half-life in mammalian cells
    • Corish P, Tyler-Smith C. Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng 1999; 12: 1035-1040
    • (1999) Protein Eng , vol.12 , pp. 1035-1040
    • Corish, P.1    Tyler-Smith, C.2
  • 62
    • 34648816174 scopus 로고    scopus 로고
    • Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain
    • Diaz-Griffero F, Kar A, Perron M, et al. Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain. J Virol 2007; 81: 10362-10378
    • (2007) J Virol , vol.81 , pp. 10362-10378
    • Diaz-Griffero, F.1    Kar, A.2    Perron, M.3
  • 63
    • 84902123429 scopus 로고    scopus 로고
    • Stabilized human TRIM5a protects human T cells from HIV-1 infection
    • Richardson MW, Guo L, Xin F, et al. Stabilized human TRIM5a protects human T cells from HIV-1 infection. Mol Ther 2014; 22: 1084-1095
    • (2014) Mol Ther , vol.22 , pp. 1084-1095
    • Richardson, M.W.1    Guo, L.2    Xin, F.3
  • 64
    • 84869194198 scopus 로고    scopus 로고
    • Innate sensing of HIV-1 assembly by tetherin induces NFjB-dependent proinflammatory responses
    • Galao RP, Le Tortorec A, Pickering S, et al. Innate sensing of HIV-1 assembly by tetherin induces NFjB-dependent proinflammatory responses. Cell Host Microbe 2012; 12: 633-644
    • (2012) Cell Host Microbe , vol.12 , pp. 633-644
    • Galao, R.P.1    Le Tortorec, A.2    Pickering, S.3
  • 65
    • 84873864091 scopus 로고    scopus 로고
    • Stimulation of NF-jB activity by the HIV restriction factor BST2
    • Tokarev A, Suarez M, Kwan W, et al. Stimulation of NF-jB activity by the HIV restriction factor BST2. J Virol 2013; 87: 2046-2057
    • (2013) J Virol , vol.87 , pp. 2046-2057
    • Tokarev, A.1    Suarez, M.2    Kwan, W.3
  • 66
    • 0034698053 scopus 로고    scopus 로고
    • Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1
    • Hofer-Warbinek R, Schmid JA, Stehlik C, et al. Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1. J Biol Chem 2000; 275: 22064-22068
    • (2000) J Biol Chem , vol.275 , pp. 22064-22068
    • Hofer-Warbinek, R.1    Schmid, J.A.2    Stehlik, C.3
  • 67
    • 0035913278 scopus 로고    scopus 로고
    • TAK1 is a ubiquitin-dependent kinase of MKK and IKK
    • Wang C, Deng L, Hong M, et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 2001; 412: 346-351
    • (2001) Nature , vol.412 , pp. 346-351
    • Wang, C.1    Deng, L.2    Hong, M.3
  • 68
    • 84863338304 scopus 로고    scopus 로고
    • Ubiquitination in signaling to and activation of IKK
    • Chen ZJ. Ubiquitination in signaling to and activation of IKK. Immunol Rev 2012; 246: 95-106
    • (2012) Immunol Rev , vol.246 , pp. 95-106
    • Chen, Z.J.1
  • 69
    • 84897504553 scopus 로고    scopus 로고
    • Phosphatase holoenzyme PP1/GADD34 negatively regulates TLR response by inhibiting TAK1 serine 412 phosphorylation
    • Gu M, Ouyang C, Lin W, et al. Phosphatase holoenzyme PP1/GADD34 negatively regulates TLR response by inhibiting TAK1 serine 412 phosphorylation. J Immunol 2014; 192: 2846-2856
    • (2014) J Immunol , vol.192 , pp. 2846-2856
    • Gu, M.1    Ouyang, C.2    Lin, W.3
  • 70
    • 15744392220 scopus 로고    scopus 로고
    • Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase Adependent phosphorylation of TAK1
    • Kobayashi Y, Mizoguchi T, Take I, et al. Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase Adependent phosphorylation of TAK1. J Biol Chem 2005; 280: 11395-11403
    • (2005) J Biol Chem , vol.280 , pp. 11395-11403
    • Kobayashi, Y.1    Mizoguchi, T.2    Take, I.3
  • 71
    • 0027168948 scopus 로고
    • The p65 subunit of NF-kappa B regulates i kappa B by two distinct mechanisms
    • Scott ML, Fujita T, Liou HC, et al. The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms. Genes Dev 1993; 7: 1266-1276
    • (1993) Genes Dev , vol.7 , pp. 1266-1276
    • Scott, M.L.1    Fujita, T.2    Liou, H.C.3
  • 72
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor kappaB signaling
    • Hoffmann A, Baltimore D. Circuitry of nuclear factor kappaB signaling. Immunol Rev 2006; 210: 171-186
    • (2006) Immunol Rev , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 73
    • 26444435364 scopus 로고    scopus 로고
    • A TNF-induced gene expression program under oscillatory NFkappaB control
    • Tian B, Nowak DE, Brasier AR. A TNF-induced gene expression program under oscillatory NFkappaB control. BMC Genomics 2005; 6: 137
    • (2005) BMC Genomics , vol.6 , pp. 137
    • Tian, B.1    Nowak, D.E.2    Brasier, A.R.3
  • 74
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NFkappaB transcription factors
    • Pahl HL. Activators and target genes of Rel/NFkappaB transcription factors. Oncogene 1999; 18: 6853-6866
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 75
    • 0037044575 scopus 로고    scopus 로고
    • The IkappaB-NF-kappaB signaling module: Temporal control and selective gene activation
    • Hoffmann A, Levchenko A, Scott ML, et al. The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 2002; 298: 1241-1245
    • (2002) Science , vol.298 , pp. 1241-1245
    • Hoffmann, A.1    Levchenko, A.2    Scott, M.L.3
  • 76
    • 48749085156 scopus 로고    scopus 로고
    • Encoding NF-kappaB temporal control in response to TNF: Distinct roles for the negative regulators IkappaBalpha and A20
    • Werner SL, Kearns JD, Zadorozhnaya V, et al. Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20. Genes Dev 2008; 22: 2093-2101
    • (2008) Genes Dev , vol.22 , pp. 2093-2101
    • Werner, S.L.1    Kearns, J.D.2    Zadorozhnaya, V.3
  • 77
    • 0035908126 scopus 로고    scopus 로고
    • Two waves of nuclear factor kappaB recruitment to target promoters
    • Saccani S, Pantano S, Natoli G. Two waves of nuclear factor kappaB recruitment to target promoters. J Exp Med 2001; 193: 1351-1359
    • (2001) J Exp Med , vol.193 , pp. 1351-1359
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 78
    • 79951840580 scopus 로고    scopus 로고
    • HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells
    • Rossetti M, Gregori S, Hauben E, et al. HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells. Hum Gene Ther 2011; 22: 177-188
    • (2011) Hum Gene Ther , vol.22 , pp. 177-188
    • Rossetti, M.1    Gregori, S.2    Hauben, E.3
  • 79
    • 4344660420 scopus 로고    scopus 로고
    • NF-kappaB and AP-1 connection: Mechanism of NF-kappaBdependent regulation of AP-1 activity
    • Fujioka S, Niu J, Schmidt C, et al. NF-kappaB and AP-1 connection: mechanism of NF-kappaBdependent regulation of AP-1 activity. Mol Cell Biol 2004; 24: 7806-7819
    • (2004) Mol Cell Biol , vol.24 , pp. 7806-7819
    • Fujioka, S.1    Niu, J.2    Schmidt, C.3
  • 80
    • 0033612571 scopus 로고    scopus 로고
    • The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN
    • Heyninck K, De Valck D, Vanden Berghe W, et al. The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN. J Cell Biol 1999; 145: 1471-1482
    • (1999) J Cell Biol , vol.145 , pp. 1471-1482
    • Heyninck, K.1    De Valck, D.2    Vanden Berghe, W.3
  • 81
    • 0024800229 scopus 로고
    • Jun-B inhibits and c-fos stimulates the transforming and transactivating activities of c-jun
    • Schutte J, Viallet J, Nau M, et al. jun-B inhibits and c-fos stimulates the transforming and transactivating activities of c-jun. Cell 1989; 59: 987-997
    • (1989) Cell , vol.59 , pp. 987-997
    • Schutte, J.1    Viallet, J.2    Nau, M.3
  • 82
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • Shaulian E, Karin M. AP-1 in cell proliferation and survival. Oncogene 2001; 20: 2390-2400
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 83
    • 0021237243 scopus 로고
    • Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS
    • Popovic M, Sarngadharan MG, Read E, et al. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 1984; 224: 497-500
    • (1984) Science , vol.224 , pp. 497-500
    • Popovic, M.1    Sarngadharan, M.G.2    Read, E.3
  • 84
    • 60549090253 scopus 로고    scopus 로고
    • Long-Term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, et al. Long-Term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009; 360: 692-698
    • (2009) N Engl J Med , vol.360 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3
  • 85
    • 79955785236 scopus 로고    scopus 로고
    • Engineering HIV-resistant human CD4 + T cells with CXCR4-specific zinc-finger nucleases
    • Wilen CB, Wang J, Tilton JC, et al. Engineering HIV-resistant human CD4 + T cells with CXCR4-specific zinc-finger nucleases. PLoS Pathog 2011; 7: e1002020
    • (2011) PLoS Pathog , vol.7 , pp. e1002020
    • Wilen, C.B.1    Wang, J.2    Tilton, J.C.3
  • 86
    • 80052637892 scopus 로고    scopus 로고
    • Pathways implicated in stem cell migration: The SDF-1/CXCR4 axis
    • Vagima Y, Lapid K, Kollet O, et al. Pathways implicated in stem cell migration: the SDF-1/CXCR4 axis. Methods Mol Biol 2011; 750: 277-289
    • (2011) Methods Mol Biol , vol.750 , pp. 277-289
    • Vagima, Y.1    Lapid, K.2    Kollet, O.3
  • 87
    • 34249336747 scopus 로고    scopus 로고
    • Safety and efficacy of a lentiviral vector containing three anti-HIV genes-CCR5 ribozyme, tat-rev siRNA, and TAR decoy-in SCID-hu mouse-derived T cells
    • Anderson J, Li MJ, Palmer B, et al. Safety and efficacy of a lentiviral vector containing three anti-HIV genes-CCR5 ribozyme, tat-rev siRNA, and TAR decoy-in SCID-hu mouse-derived T cells. Mol Ther 2007; 15: 1182-1188
    • (2007) Mol Ther , vol.15 , pp. 1182-1188
    • Anderson, J.1    Li, M.J.2    Palmer, B.3
  • 88
    • 34548574859 scopus 로고    scopus 로고
    • Lentiviral vectors that carry anti-HIV shRNAs: Problems and solutions
    • Ter Brake O, Berkhout B. Lentiviral vectors that carry anti-HIV shRNAs: problems and solutions. J Gene Med 2007; 9: 743-750
    • (2007) J Gene Med , vol.9 , pp. 743-750
    • Ter Brake, O.1    Berkhout, B.2
  • 89
    • 0142124143 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 escape from RNA interference
    • Boden D, Pusch O, Lee F, et al. Human immunodeficiency virus type 1 escape from RNA interference. J Virol 2003; 77: 11531-11535
    • (2003) J Virol , vol.77 , pp. 11531-11535
    • Boden, D.1    Pusch, O.2    Lee, F.3
  • 90
    • 85015391748 scopus 로고    scopus 로고
    • HIV-1 escape from RNAi antivirals: Yet another Houdini action
    • Berkhout B, Das AT. HIV-1 escape from RNAi antivirals: yet another Houdini action? Mol Ther Nucleic Acids 2012; 1: e26
    • (2012) Mol Ther Nucleic Acids , vol.1 , pp. e26
    • Berkhout, B.1    Das, A.T.2
  • 91
    • 0033214895 scopus 로고    scopus 로고
    • Inhibiting HIV-1 entry: Discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket
    • Eckert DM, Malashkevich VN, Hong LH, et al. Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket. Cell 1999; 99: 103-115
    • (1999) Cell , vol.99 , pp. 103-115
    • Eckert, D.M.1    Malashkevich, V.N.2    Hong, L.H.3
  • 92
    • 9144270207 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides
    • Egelhofer M, Brandenburg G, Martinius H, et al. Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides. J Virol 2004; 78: 568-575
    • (2004) J Virol , vol.78 , pp. 568-575
    • Egelhofer, M.1    Brandenburg, G.2    Martinius, H.3
  • 93
    • 65349113010 scopus 로고    scopus 로고
    • Mutations in gp120 contribute to the resistance of human immunodeficiency virus type 1 to membraneanchored C-peptide maC46
    • Hermann FG, Egerer L, Brauer F, et al. Mutations in gp120 contribute to the resistance of human immunodeficiency virus type 1 to membraneanchored C-peptide maC46. J Virol 2009; 83: 4844-4853
    • (2009) J Virol , vol.83 , pp. 4844-4853
    • Hermann, F.G.1    Egerer, L.2    Brauer, F.3
  • 94
    • 84862927851 scopus 로고    scopus 로고
    • Mutations of Gln64 in the HIV-1 gp41 N-Terminal heptad repeat render viruses resistant to peptide HIV fusion inhibitors targeting the gp41 pocket
    • Yu X, Lu L, Cai L, et al. Mutations of Gln64 in the HIV-1 gp41 N-Terminal heptad repeat render viruses resistant to peptide HIV fusion inhibitors targeting the gp41 pocket. J Virol 2012; 86: 589-593
    • (2012) J Virol , vol.86 , pp. 589-593
    • Yu, X.1    Lu, L.2    Cai, L.3
  • 95
    • 31144469701 scopus 로고    scopus 로고
    • Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors
    • Cullen BR. Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors. J Virol 2006; 80: 1067-1076
    • (2006) J Virol , vol.80 , pp. 1067-1076
    • Cullen, B.R.1
  • 96
    • 0038107587 scopus 로고    scopus 로고
    • Species-specific exclusion of APOBEC3g from HIV-1 virions by Vif
    • Mariani R, Chen D, Schrofelbauer B, et al. Species-specific exclusion of APOBEC3g from HIV-1 virions by Vif. Cell 2003; 114: 21-31
    • (2003) Cell , vol.114 , pp. 21-31
    • Mariani, R.1    Chen, D.2    Schrofelbauer, B.3
  • 97
    • 77956832938 scopus 로고    scopus 로고
    • TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species
    • Kirmaier A, Wu F, Newman RM, et al. TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species. PLoS Biol 2010; 8: e1000462
    • (2010) PLoS Biol , vol.8 , pp. e1000462
    • Kirmaier, A.1    Wu, F.2    Newman, R.M.3
  • 98
    • 0346057853 scopus 로고    scopus 로고
    • Capsiddependent and-independent postentry restrict tion of primate lentivirus tropism in rodent cells
    • Hatziioannou T, Cowan S, Bieniasz PD. Capsiddependent and-independent postentry restrict tion of primate lentivirus tropism in rodent cells. J Virol 2004; 78: 1006-1011
    • (2004) J Virol , vol.78 , pp. 1006-1011
    • Hatziioannou, T.1    Cowan, S.2    Bieniasz, P.D.3
  • 99
    • 13944259674 scopus 로고    scopus 로고
    • Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction
    • Stremlau M, Perron M, Welikala S, et al. Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction. J Virol 2005; 79: 3139-3145
    • (2005) J Virol , vol.79 , pp. 3139-3145
    • Stremlau, M.1    Perron, M.2    Welikala, S.3
  • 100
    • 37849044361 scopus 로고    scopus 로고
    • Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha
    • Maillard PV, Reynard S, Serhan F, et al. Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha. PLoS Pathog 2007; 3: e200
    • (2007) PLoS Pathog , vol.3 , pp. e200
    • Maillard, P.V.1    Reynard, S.2    Serhan, F.3
  • 101
    • 26844573354 scopus 로고    scopus 로고
    • Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in OldWorld monkey cells
    • Berthoux L, Sebastian S, Sokolskaja E, et al. Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in OldWorld monkey cells. Proc Natl Acad Sci USA 2005; 102: 14849-14853
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14849-14853
    • Berthoux, L.1    Sebastian, S.2    Sokolskaja, E.3
  • 102
    • 33646457944 scopus 로고    scopus 로고
    • Cyclophilin A renders human immunodeficiency virus type 1 sensitive to Old World monkey but not human TRIM5 alpha antiviral activity
    • Keckesova Z, Ylinen LM, Towers GJ. Cyclophilin A renders human immunodeficiency virus type 1 sensitive to Old World monkey but not human TRIM5 alpha antiviral activity. J Virol 2006; 80: 4683-4690
    • (2006) J Virol , vol.80 , pp. 4683-4690
    • Keckesova, Z.1    Ylinen, L.M.2    Towers, G.J.3
  • 103
    • 33745861280 scopus 로고    scopus 로고
    • Cyclophilin A: An auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1
    • Stremlau M, Song B, Javanbakht H, et al. Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1. Virology 2006; 351: 112-120
    • (2006) Virology , vol.351 , pp. 112-120
    • Stremlau, M.1    Song, B.2    Javanbakht, H.3
  • 104
    • 84888122810 scopus 로고    scopus 로고
    • Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA
    • Orzalli MH, Conwell SE, Berrios C, et al. Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci USA 2013; 110: E4492-E4501
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. E4492-E4501
    • Orzalli, M.H.1    Conwell, S.E.2    Berrios, C.3
  • 105
    • 36349009391 scopus 로고    scopus 로고
    • A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells
    • Caposio P, Gugliesi F, Zannetti C, et al. A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells. J Biol Chem 2007; 282: 33515-33529
    • (2007) J Biol Chem , vol.282 , pp. 33515-33529
    • Caposio, P.1    Gugliesi, F.2    Zannetti, C.3
  • 106
    • 84902096048 scopus 로고    scopus 로고
    • Development and applications of CRISPR-Cas9 for genome engineering
    • Hsu PD, Lander ES, Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 2014; 157: 1262-1278
    • (2014) Cell , vol.157 , pp. 1262-1278
    • Hsu, P.D.1    Lander, E.S.2    Zhang, F.3
  • 107
    • 84902095353 scopus 로고    scopus 로고
    • Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
    • Yin H, Xue W, Chen S, et al. Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. Nat Biotechnol 2014; 32: 551-553
    • (2014) Nat Biotechnol , vol.32 , pp. 551-553
    • Yin, H.1    Xue, W.2    Chen, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.