TRIM5αrh expression restricts HIV-1 infection in lentiviral vector-transduced CD34+-cell-derived macrophages

Molecular Therapy

Volumn 12, Issue 4, 2005, Pages 687-696

  Anderson, Joseph ^a   Akkina, Ramesh ^a  

^a Department of Ecosystem Science and Sustainability   (United States)

Author keywords

HIV 1 restriction; HIV AIDS gene therapy; Lentiviral vector; Retroviral restriction; Transgenic macrophages; TRIM5

Indexed keywords

B7 ANTIGEN; CD14 ANTIGEN; CD34 ANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CYTOPLASM PROTEIN; LENTIVIRUS VECTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG; CARRIER PROTEIN; TRIM5 PROTEIN, HUMAN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIGEN EXPRESSION; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MACROPHAGE; MONKEY; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; SPECIES DIFFERENCE; STEM CELL GENE THERAPY; TRANSGENE; TRANSLATION REGULATION; VIRAL GENE DELIVERY SYSTEM; VIRUS RESISTANCE; CELL DIFFERENTIATION; DRUG EFFECT; GENE THERAPY; GENE VECTOR; GENETICS; IMMUNOLOGY; LENTIVIRINAE; METABOLISM;

HUMAN IMMUNODEFICIENCY VIRUS 1; MIRIDAE; SIMIAE;

ANTIGENS, CD34; CARRIER PROTEINS; CELL DIFFERENTIATION; GENE THERAPY; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; HIV INFECTIONS; HIV-1; HUMANS; LENTIVIRUS; MACROPHAGES; RECEPTORS, CCR5; RECEPTORS, CXCR4; TRANSDUCTION, GENETIC; TRANSGENES;

EID: 25144460493     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.07.291     Document Type: Article

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