Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression

Journal of Gene Medicine

Volumn 16, Issue 3-4, 2014, Pages 97-106

  Yin, Yalei ^a   Takahashi, Yuki ^a   Ebisuura, Norifumi ^a   Nishikawa, Makiya ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Antibody production; Firefly luciferase; Gaussia luciferase; Hydrodynamic injection; Immune response; Plasmid DNA

Indexed keywords

ALANINE AMINOTRANSFERASE; FIREFLY LUCIFERASE; GAMMA INTERFERON; IMMUNOGLOBULIN G; PLASMID DNA; LUCIFERASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL MEMBRANE PERMEABILITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; FEMALE; GENE ACTIVITY; HISTOCHEMISTRY; HUMORAL IMMUNITY; HYDRODYNAMICS; HYDRODYNAMICS BASED TRANSFECTION; IMMUNE RESPONSE; KUPFFER CELL; LIVER CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SPLEEN CELL; STABLE EXPRESSION; TRANSGENE; ANIMAL; BLOOD; C57BL MOUSE; CYTOLOGY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENE THERAPY; GENE VECTOR; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; METABOLISM; PLASMID; SPLEEN;

ALANINE TRANSAMINASE; ANIMALS; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION REGULATION; GENETIC THERAPY; GENETIC VECTORS; HEPATOCYTES; IMMUNITY, CELLULAR; INTERFERON-GAMMA; LIVER; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; PLASMIDS; SPLEEN; TRANSGENES;

EID: 84900448514     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.2763     Document Type: Article

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