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Volumn 82, Issue 5, 2001, Pages 1027-1041

The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASPARTIC ACID; BETA GLUCURONIDASE; GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; POLYPROTEIN; PROTEINASE; RADIOISOTOPE; VIRUS PROTEIN;

EID: 0035005706     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-82-5-1027     Document Type: Article
Times cited : (453)

References (53)
  • 1
    • 0034637111 scopus 로고    scopus 로고
    • The complete atomic structure of the large ribosomal subunit at 2·4 Å resolution
    • Ban, N., Nissen, P., Hansen, J., Moore, P. B. & Steitz, T. A. (2000). The complete atomic structure of the large ribosomal subunit at 2·4 Å resolution. Science 289, 905-920.
    • (2000) Science , vol.289 , pp. 905-920
    • Ban, N.1    Nissen, P.2    Hansen, J.3    Moore, P.B.4    Steitz, T.A.5
  • 2
    • 0030999377 scopus 로고    scopus 로고
    • Modulation of bovine T cell responses by IL-12 and the influence of IL-4 on interferon-gamma responses to respiratory syncytial virus
    • Camon, E. B., Chaplin, P. J., Howard, C. J. & Collins, R. A. (1997). Modulation of bovine T cell responses by IL-12 and the influence of IL-4 on interferon-gamma responses to respiratory syncytial virus. Biochemical Society Transactions 25, S291.
    • (1997) Biochemical Society Transactions , vol.25
    • Camon, E.B.1    Chaplin, P.J.2    Howard, C.J.3    Collins, R.A.4
  • 4
    • 0032524792 scopus 로고    scopus 로고
    • Influence of IL-12 on interferon-gamma production by bovine leucocyte subsets in response to bovine respiratory syncytial virus
    • Collins, R. A., Camon, E. B., Chaplin, P. J. & Howard, C. J. (1998). Influence of IL-12 on interferon-gamma production by bovine leucocyte subsets in response to bovine respiratory syncytial virus. Veterinary Immunology and Immunopathology 63, 69-72.
    • (1998) Veterinary Immunology and Immunopathology , vol.63 , pp. 69-72
    • Collins, R.A.1    Camon, E.B.2    Chaplin, P.J.3    Howard, C.J.4
  • 6
    • 0034284152 scopus 로고    scopus 로고
    • Tricistronic and tetracistronic retroviral vectors for gene transfer
    • De Felipe, P. & Izquierdo, M. (2000). Tricistronic and tetracistronic retroviral vectors for gene transfer. Human Gene Therapy 11, 1921-1931.
    • (2000) Human Gene Therapy , vol.11 , pp. 1921-1931
    • De Felipe, P.1    Izquierdo, M.2
  • 7
    • 0033030109 scopus 로고    scopus 로고
    • Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy. Gene
    • De Felipe, P., Martín, V., Cortés, M. L., Ryan, M. D. & Izquierdo, M. (1999). Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy. Gene Therapy 6, 198-208.
    • (1999) Therapy , vol.6 , pp. 198-208
    • De Felipe, P.1    Martín, V.2    Cortés, M.L.3    Ryan, M.D.4    Izquierdo, M.5
  • 9
    • 0032802169 scopus 로고    scopus 로고
    • Sequence analysis of a porcine enterovirus serotype I isolate: Relationships with other picornaviruses
    • Doherty, M., Todd, D., McFerran, N. & Hoey, E. M. (1999). Sequence analysis of a porcine enterovirus serotype I isolate: relationships with other picornaviruses. Journal of General Virology 80, 1929-1941.
    • (1999) Journal of General Virology , vol.80 , pp. 1929-1941
    • Doherty, M.1    Todd, D.2    McFerran, N.3    Hoey, E.M.4
  • 11
    • 0035015174 scopus 로고    scopus 로고
    • Analysis of the apthovirus 2A/2B polyprotein 'cleavage mechanism' indicates not a proteolytic reaction, but a novel translational effect: A putative ribosomal 'skip'
    • Donnelly, M. L. L., Luke, G., Mehrotra, A., Li, X., Hughes, L E., Gani, D. & Ryan, M. D. (2001). Analysis of the apthovirus 2A/2B polyprotein 'cleavage mechanism' indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. Journal of General Virology 82, 1013-1025.
    • (2001) Journal of General Virology , vol.82 , pp. 1013-1025
    • Donnelly, M.L.L.1    Luke, G.2    Mehrotra, A.3    Li, X.4    Hughes, L.E.5    Gani, D.6    Ryan, M.D.7
  • 12
    • 0029870925 scopus 로고    scopus 로고
    • Programmed translational frameshifting
    • Farabaugh, P. J. (1996). Programmed translational frameshifting. Microbiological Reviews 60, 103-134.
    • (1996) Microbiological Reviews , vol.60 , pp. 103-134
    • Farabaugh, P.J.1
  • 13
    • 0023109951 scopus 로고
    • Deamidation, isomerization, and racemization of asparaginyl and aspartyl residues in peptides: Succinamide-linked reactions that contribute to protein degradation
    • Geiger, T. & Clarke, S. (1987). Deamidation, isomerization, and racemization of asparaginyl and aspartyl residues in peptides: succinamide-linked reactions that contribute to protein degradation. Journal of Biological Chemistry 262, 785-794.
    • (1987) Journal of Biological Chemistry , vol.262 , pp. 785-794
    • Geiger, T.1    Clarke, S.2
  • 14
    • 0034652706 scopus 로고    scopus 로고
    • Engineering cowpea mosaic virus RNA-2 into a vector to express heterologous proteins in plants
    • Gopinath, K., Wellink, J., Porta, C., Taylor, K. M., Lomonossoff, G. P. & van Kammen, A. (2000). Engineering cowpea mosaic virus RNA-2 into a vector to express heterologous proteins in plants. Virology 267, 159-173.
    • (2000) Virology , vol.267 , pp. 159-173
    • Gopinath, K.1    Wellink, J.2    Porta, C.3    Taylor, K.M.4    Lomonossoff, G.P.5    Van Kammen, A.6
  • 15
    • 0034715792 scopus 로고    scopus 로고
    • Analysis of the complete genome sequence of acute bee paralysis virus shows that it belongs to the novel group of insect-infecting RNA viruses
    • Govan, V. A., Leat, N., Allsopp, M. & Davison, S. (2000). Analysis of the complete genome sequence of acute bee paralysis virus shows that it belongs to the novel group of insect-infecting RNA viruses. Virology 277, 457-463.
    • (2000) Virology , vol.277 , pp. 457-463
    • Govan, V.A.1    Leat, N.2    Allsopp, M.3    Davison, S.4
  • 16
    • 0029665575 scopus 로고    scopus 로고
    • Mutational analysis of the encephalomyocarditis virus primary cleavage
    • Hahn, H. & Palmenberg, A. C. (1996). Mutational analysis of the encephalomyocarditis virus primary cleavage. Journal of Virology 70, 6870-6875.
    • (1996) Journal of Virology , vol.70 , pp. 6870-6875
    • Hahn, H.1    Palmenberg, A.C.2
  • 17
    • 0021141004 scopus 로고
    • Complete nucleotide sequence of an unusual mobile element from Trypanosoma brucei
    • Hasan, G., Turner, M. J. & Cordingley, J. S. (1984). Complete nucleotide sequence of an unusual mobile element from Trypanosoma brucei. Cell 37, 333-341.
    • (1984) Cell , vol.37 , pp. 333-341
    • Hasan, G.1    Turner, M.J.2    Cordingley, J.S.3
  • 18
    • 0031884586 scopus 로고    scopus 로고
    • Analysis of genetic information of an insect picorna-like virus, infectious flacherie virus of silkworm: Evidence for evolutionary relationships among insect, mammalian and plant picorna(-like) viruses
    • Isawa, H., Asano, S., Sahara, K., Iizuka, T. & Bando, H. (1998). Analysis of genetic information of an insect picorna-like virus, infectious flacherie virus of silkworm: evidence for evolutionary relationships among insect, mammalian and plant picorna(-like) viruses. Archives of Virology 143, 127-143.
    • (1998) Archives of Virology , vol.143 , pp. 127-143
    • Isawa, H.1    Asano, S.2    Sahara, K.3    Iizuka, T.4    Bando, H.5
  • 21
    • 0031964588 scopus 로고    scopus 로고
    • The novel genome organization of the insect picorna-like virus, Drosophila C virus, suggests this virus belongs to a previously undescribed virus family
    • Johnson, K. N. & Christian, P. D. (1998). The novel genome organization of the insect picorna-like virus, Drosophila C virus, suggests this virus belongs to a previously undescribed virus family. Journal of General Virology 79, 191-203.
    • (1998) Journal of General Virology , vol.79 , pp. 191-203
    • Johnson, K.N.1    Christian, P.D.2
  • 22
    • 0000034976 scopus 로고
    • N5-Methylasparagine and asparagine as nucleophiles in peptides: Main-chain and side-chain amide cleavage
    • Klotz, A. V. & Thomas, B. A. (1993). N5-Methylasparagine and asparagine as nucleophiles in peptides: main-chain and side-chain amide cleavage. Journal of Organic Chemistry 58, 6985-6989.
    • (1993) Journal of Organic Chemistry , vol.58 , pp. 6985-6989
    • Klotz, A.V.1    Thomas, B.A.2
  • 23
    • 0032763630 scopus 로고    scopus 로고
    • Production of biologically active, heterodimeric porcine interleukin-12 using a monocistronic baculoviral expression system
    • Kokuho, T., Watanabe, S., Yokomizo, Y. & Inumaru, S. (1999). Production of biologically active, heterodimeric porcine interleukin-12 using a monocistronic baculoviral expression system. Veterinary Immunology and Immunopathology 72, 289-302.
    • (1999) Veterinary Immunology and Immunopathology , vol.72 , pp. 289-302
    • Kokuho, T.1    Watanabe, S.2    Yokomizo, Y.3    Inumaru, S.4
  • 24
    • 0027327319 scopus 로고
    • Common ring motifs in proteins involving asparagine or glutamine amide groups hydrogen-bonded to main-chain atoms
    • Le Questel, J.-Y., Morris, D. G., MacCallum, P. H., Poet, R. & Milner-White, E. J. (1993). Common ring motifs in proteins involving asparagine or glutamine amide groups hydrogen-bonded to main-chain atoms. Journal of Molecular Biology 231, 888-896.
    • (1993) Journal of Molecular Biology , vol.231 , pp. 888-896
    • Le Questel, J.-Y.1    Morris, D.G.2    MacCallum, P.H.3    Poet, R.4    Milner-White, E.J.5
  • 26
    • 0023053308 scopus 로고
    • Sterochemical analysis of ribosomal transpeptidation ; conformation of the nascent peptide
    • Lim, V. L. & Spirin, A. S. (1986). Sterochemical analysis of ribosomal transpeptidation ; conformation of the nascent peptide. Journal of Molecular Biology 188, 565-577.
    • (1986) Journal of Molecular Biology , vol.188 , pp. 565-577
    • Lim, V.L.1    Spirin, A.S.2
  • 27
    • 0028902026 scopus 로고
    • Characterization of a non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi: Homology of the first ORF with the ape family of DNA repair enzymes
    • Martin, F., Maranon, C., Olivares, M., Alonso, C. & Lopez, M. C. (1995). Characterization of a non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi: homology of the first ORF with the ape family of DNA repair enzymes. Journal of Molecular Biology 247, 49-59.
    • (1995) Journal of Molecular Biology , vol.247 , pp. 49-59
    • Martin, F.1    Maranon, C.2    Olivares, M.3    Alonso, C.4    Lopez, M.C.5
  • 28
    • 0029819347 scopus 로고    scopus 로고
    • Foot-and-mouth disease virus 2A protease mediates cleavage in attenuated Sabin 3 poliovirus vectors engineered for delivery of foreign antigens
    • Mattion, N. M., Harnish, E. C., Crowley, J. C. & Reilly, P. A. (1996). Foot-and-mouth disease virus 2A protease mediates cleavage in attenuated Sabin 3 poliovirus vectors engineered for delivery of foreign antigens. Journal of Virology 70, 8124-8127.
    • (1996) Journal of Virology , vol.70 , pp. 8124-8127
    • Mattion, N.M.1    Harnish, E.C.2    Crowley, J.C.3    Reilly, P.A.4
  • 30
    • 0001412985 scopus 로고
    • Structural requirements for puromycin inhibition of protein synthesis
    • Nathans, D. & Niedle, A. (1963). Structural requirements for puromycin inhibition of protein synthesis. Nature 197, 1076-1077.
    • (1963) Nature , vol.197 , pp. 1076-1077
    • Nathans, D.1    Niedle, A.2
  • 31
    • 0034637161 scopus 로고    scopus 로고
    • The structural basis of ribosome activity in peptide bond synthesis
    • Nissen, P., Hansen, J., Ban, N., Moore, P. B. & Steitz, T. A. (2000). The structural basis of ribosome activity in peptide bond synthesis. Science 289, 920-930.
    • (2000) Science , vol.289 , pp. 920-930
    • Nissen, P.1    Hansen, J.2    Ban, N.3    Moore, P.B.4    Steitz, T.A.5
  • 32
    • 0034630854 scopus 로고    scopus 로고
    • Rotavirus VP6 expressed by PVX vectors in Nicotiana benthamiana coats PVX rods and also assembles into viruslike particles
    • O'Brien, G. J., Bryant, C. J., Voogd, C., Greenberg, H. B., Gardner, R. C. & Bellamy, A. R. (2000). Rotavirus VP6 expressed by PVX vectors in Nicotiana benthamiana coats PVX rods and also assembles into viruslike particles. Virology 270, 444-453.
    • (2000) Virology , vol.270 , pp. 444-453
    • O'Brien, G.J.1    Bryant, C.J.2    Voogd, C.3    Greenberg, H.B.4    Gardner, R.C.5    Bellamy, A.R.6
  • 33
    • 0028856106 scopus 로고
    • Inducible expression of the P, V, and NP genes of the paramyxovirus simian virus 5 in cell lines and an examination of the NP-P and NP-V interactions
    • Precious, B., Young, D. F., Bermingham, A., Fearns, R., Ryan, M. D. & Randall, R. E. (1995). Inducible expression of the P, V, and NP genes of the paramyxovirus simian virus 5 in cell lines and an examination of the NP-P and NP-V interactions. Journal of Virology 69, 8001-8010.
    • (1995) Journal of Virology , vol.69 , pp. 8001-8010
    • Precious, B.1    Young, D.F.2    Bermingham, A.3    Fearns, R.4    Ryan, M.D.5    Randall, R.E.6
  • 35
    • 0026095606 scopus 로고
    • Molecular analysis of the gene 6 from a porcine group C rotavirus that encodes the NS34 equivalent of group a rotaviruses
    • Qian, Y., Jiang, B., Saif, L. J., Kang, S. Y., Ojeh, C. K. & Green, K. Y. (1991). Molecular analysis of the gene 6 from a porcine group C rotavirus that encodes the NS34 equivalent of group a rotaviruses. Virology 184, 752-757.
    • (1991) Virology , vol.184 , pp. 752-757
    • Qian, Y.1    Jiang, B.2    Saif, L.J.3    Kang, S.Y.4    Ojeh, C.K.5    Green, K.Y.6
  • 36
    • 2642610314 scopus 로고    scopus 로고
    • Phloem unloading in sink leaves of Nicotiana benthamiana: Comparison of a fluorescent solute with a fluorescent virus
    • Roberts, A. G., Santa Cruz, S., Roberts, I. M., Prior, D. A. M., Turgeon, R. & Oparka, K. J. (1997). Phloem unloading in sink leaves of Nicotiana benthamiana: Comparison of a fluorescent solute with a fluorescent virus. Plant Cell 9, 1381-1396.
    • (1997) Plant Cell , vol.9 , pp. 1381-1396
    • Roberts, A.G.1    Santa Cruz, S.2    Roberts, I.M.3    Prior, D.A.M.4    Turgeon, R.5    Oparka, K.J.6
  • 37
    • 0031014417 scopus 로고    scopus 로고
    • Isolation and analysis of a gene encoding alpha-glucuronidase, an enzyme with a novel primary structure involved in the breakdown of xylan
    • Ruile, P., Winterhalter, C. & Liebl, W. (1997). Isolation and analysis of a gene encoding alpha-glucuronidase, an enzyme with a novel primary structure involved in the breakdown of xylan. Molecular Microbiology 23, 267-279.
    • (1997) Molecular Microbiology , vol.23 , pp. 267-279
    • Ruile, P.1    Winterhalter, C.2    Liebl, W.3
  • 38
    • 0028058011 scopus 로고
    • Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein
    • Ryan, M. D. & Drew, J. (1994). Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein. EMBO Journal 13, 928-933.
    • (1994) EMBO Journal , vol.13 , pp. 928-933
    • Ryan, M.D.1    Drew, J.2
  • 39
    • 0025934319 scopus 로고
    • Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence
    • Ryan, M. D., King, A. M. Q. & Thomas, G. P. (1991). Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence. Journal of General Virology 72, 2727-2732.
    • (1991) Journal of General Virology , vol.72 , pp. 2727-2732
    • Ryan, M.D.1    King, A.M.Q.2    Thomas, G.P.3
  • 40
    • 0032830440 scopus 로고    scopus 로고
    • A model for non-stoichiometric, co-translational protein scission in eukaryotic ribosomes
    • Ryan, M. D., Donnelly, M. L. L., Lewis, A., Mehrotra, A. P., Wilkie, J. & Gani, D. (1999). A model for non-stoichiometric, co-translational protein scission in eukaryotic ribosomes. Bioorganic Chemistry 27, 55-79.
    • (1999) Bioorganic Chemistry , vol.27 , pp. 55-79
    • Ryan, M.D.1    Donnelly, M.L.L.2    Lewis, A.3    Mehrotra, A.P.4    Wilkie, J.5    Gani, D.6
  • 41
    • 0014848307 scopus 로고
    • Substrate specificity of ribosomal peptidyl transferase. The effect of the nature of the amino acid side chain on the acceptor activity of 2′(3′)-O-aminoacyladenosines
    • Rychlik, I., Cerna, J., Chaldek, S., Pulkrabek, P. & Zemlicke, J. (1970). Substrate specificity of ribosomal peptidyl transferase. The effect of the nature of the amino acid side chain on the acceptor activity of 2′(3′)-O-aminoacyladenosines. European Journal of Biochemistry 16, 136-142.
    • (1970) European Journal of Biochemistry , vol.16 , pp. 136-142
    • Rychlik, I.1    Cerna, J.2    Chaldek, S.3    Pulkrabek, P.4    Zemlicke, J.5
  • 42
    • 0029060001 scopus 로고
    • Replicating foamy virus-based vectors directing high-level expression of foreign genes
    • Schmidt, M. & Rethwilm, A. (1995). Replicating foamy virus-based vectors directing high-level expression of foreign genes. Virology 210, 167-178.
    • (1995) Virology , vol.210 , pp. 167-178
    • Schmidt, M.1    Rethwilm, A.2
  • 43
    • 0032906979 scopus 로고    scopus 로고
    • Two-helper RNA system for production of recombinant Semliki Forest virus particles
    • Smerdou, C. & Liljestrom, P. (1999). Two-helper RNA system for production of recombinant Semliki Forest virus particles. Journal of Virology 73, 1092-1098.
    • (1999) Journal of Virology , vol.73 , pp. 1092-1098
    • Smerdou, C.1    Liljestrom, P.2
  • 45
    • 0033865748 scopus 로고    scopus 로고
    • Essential and dispensable virus-encoded replication elements revealed by efforts to develop hypoviruses as gene expression vectors
    • Suzuki, N., Geletka, L. M. & Nuss, D. L. (2000). Essential and dispensable virus-encoded replication elements revealed by efforts to develop hypoviruses as gene expression vectors. Journal of Virology 74, 7568-7577.
    • (2000) Journal of Virology , vol.74 , pp. 7568-7577
    • Suzuki, N.1    Geletka, L.M.2    Nuss, D.L.3
  • 46
    • 0033946897 scopus 로고    scopus 로고
    • Limitations on the use of fused green fluorescent protein to investigate structure-function relationships for the cauliflower mosaic virus movement protein
    • Thomas, C. L. & Maule, A. J. (2000). Limitations on the use of fused green fluorescent protein to investigate structure-function relationships for the cauliflower mosaic virus movement protein. Journal of General Virology 81, 1851-1855.
    • (2000) Journal of General Virology , vol.81 , pp. 1851-1855
    • Thomas, C.L.1    Maule, A.J.2
  • 48
    • 0033558747 scopus 로고    scopus 로고
    • Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes
    • Varnavski, A. N. & Khromykh, A. A. (1999). Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes. Virology 255, 366-375.
    • (1999) Virology , vol.255 , pp. 366-375
    • Varnavski, A.N.1    Khromykh, A.A.2
  • 49
    • 0034001812 scopus 로고    scopus 로고
    • Stable high level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectors
    • Varnavski, A. N., Young, P. R. & Khromykh, A. A. (2000). Stable high level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectors. Journal of Virology 74, 4394-4403.
    • (2000) Journal of Virology , vol.74 , pp. 4394-4403
    • Varnavski, A.N.1    Young, P.R.2    Khromykh, A.A.3
  • 50
    • 0024279235 scopus 로고
    • Analysis and prediction of the different types of β-turn in proteins
    • Wilmot, C. M. & Thornton, J. M. (1988). Analysis and prediction of the different types of β-turn in proteins. Journal of Molecular Biology 203, 221-232.
    • (1988) Journal of Molecular Biology , vol.203 , pp. 221-232
    • Wilmot, C.M.1    Thornton, J.M.2
  • 51
    • 0033920258 scopus 로고    scopus 로고
    • Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites
    • Wilson, J. E., Powell, M. J., Hoover, S. E. & Sarnow, P. (2000). Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites. Molecular and Cellular Biology 20, 4990-4999.
    • (2000) Molecular and Cellular Biology , vol.20 , pp. 4990-4999
    • Wilson, J.E.1    Powell, M.J.2    Hoover, S.E.3    Sarnow, P.4
  • 52
    • 0029766556 scopus 로고    scopus 로고
    • Equine rhinovirus serotypes 1 and 2: Relationship to each other and to aphthoviruses and cardioviruses
    • Wutz, G., Auer, H., Nowotny, N., Skern, T. & Kuechler, E. (1996). Equine rhinovirus serotypes 1 and 2: relationship to each other and to aphthoviruses and cardioviruses. Journal of General Virology 77, 1719-1730.
    • (1996) Journal of General Virology , vol.77 , pp. 1719-1730
    • Wutz, G.1    Auer, H.2    Nowotny, N.3    Skern, T.4    Kuechler, E.5
  • 53


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