-
1
-
-
80053510653
-
Pain as a global public health priority
-
PID: 21978149
-
Goldberg DS, McGee SJ. Pain as a global public health priority. BMC Public Health. 2011;11:770.
-
(2011)
BMC Public Health
, vol.11
, pp. 770
-
-
Goldberg, D.S.1
McGee, S.J.2
-
2
-
-
33748053352
-
Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?
-
COI: 1:CAS:528:DC%2BD28XptFCitrw%3D, PID: 16730375
-
Verri WA Jr, Cunha TM, Parada CA, Poole S, Cunha FQ, Ferreira SH. Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? Pharmacol Ther. 2006;112:116–38.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 116-138
-
-
Verri, W.A.1
Cunha, T.M.2
Parada, C.A.3
Poole, S.4
Cunha, F.Q.5
Ferreira, S.H.6
-
3
-
-
30644463076
-
Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-alpha
-
COI: 1:CAS:528:DC%2BD28XmtV2mtQ%3D%3D, PID: 16399694
-
Jin X, Gereau RW. Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-alpha. J Neurosci. 2006;26:246–55.
-
(2006)
J Neurosci
, vol.26
, pp. 246-255
-
-
Jin, X.1
Gereau, R.W.2
-
4
-
-
58149387593
-
Nociceptors are interleukin-1beta sensors
-
COI: 1:CAS:528:DC%2BD1MXis1eksQ%3D%3D, PID: 19109489
-
Binshtok AM, Wang H, Zimmermann K, Amaya F, Vardeh D, Shi L, et al. Nociceptors are interleukin-1beta sensors. J Neurosci. 2008;28:14062–73.
-
(2008)
J Neurosci
, vol.28
, pp. 14062-14073
-
-
Binshtok, A.M.1
Wang, H.2
Zimmermann, K.3
Amaya, F.4
Vardeh, D.5
Shi, L.6
-
5
-
-
13444306159
-
A cascade of cytokines mediates mechanical inflammatory hypernociception in mice
-
COI: 1:CAS:528:DC%2BD2MXhs1Klu7k%3D, PID: 15665080
-
Cunha TM, Verri WA Jr, Silva JS, Poole S, Cunha FQ, Ferreira SH. A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc Natl Acad Sci U S A. 2005;102:1755–60.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1755-1760
-
-
Cunha, T.M.1
Verri, W.A.2
Silva, J.S.3
Poole, S.4
Cunha, F.Q.5
Ferreira, S.H.6
-
6
-
-
84876113308
-
IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2
-
COI: 1:CAS:528:DC%2BC3sXmtFalu7Y%3D, PID: 23347081
-
Zarpelon AC, Cunha TM, Alves-Filho JC, Pinto LG, Ferreira SH, McInnes IB, et al. IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2. Br J Pharmacol. 2013;169:90–101.
-
(2013)
Br J Pharmacol
, vol.169
, pp. 90-101
-
-
Zarpelon, A.C.1
Cunha, T.M.2
Alves-Filho, J.C.3
Pinto, L.G.4
Ferreira, S.H.5
McInnes, I.B.6
-
7
-
-
43449100478
-
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception
-
COI: 1:CAS:528:DC%2BD1cXkt1agsrk%3D, PID: 18203872
-
Cunha TM, Verri WA Jr, Schivo IR, Napimoga MH, Parada CA, Poole S, et al. Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol. 2008;83:824–32.
-
(2008)
J Leukoc Biol
, vol.83
, pp. 824-832
-
-
Cunha, T.M.1
Verri, W.A.2
Schivo, I.R.3
Napimoga, M.H.4
Parada, C.A.5
Poole, S.6
-
8
-
-
77957943307
-
Intravascular danger signals guide neutrophils to sites of sterile inflammation
-
COI: 1:CAS:528:DC%2BC3cXht1OisL7O, PID: 20947763
-
McDonald B, Pittman K, Menezes GB, Hirota SA, Slaba I, Waterhouse CC, et al. Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science. 2010;330:362–6.
-
(2010)
Science
, vol.330
, pp. 362-366
-
-
McDonald, B.1
Pittman, K.2
Menezes, G.B.3
Hirota, S.A.4
Slaba, I.5
Waterhouse, C.C.6
-
9
-
-
3042704091
-
Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation
-
COI: 1:CAS:528:DC%2BD2cXlsFWqu7Y%3D, PID: 15242550
-
Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Ndengele M, Salvemini D. Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation. Antioxid Redox Signal. 2004;6:699–704.
-
(2004)
Antioxid Redox Signal
, vol.6
, pp. 699-704
-
-
Cuzzocrea, S.1
Pisano, B.2
Dugo, L.3
Ianaro, A.4
Ndengele, M.5
Salvemini, D.6
-
10
-
-
2442648975
-
A newly identified role for superoxide in inflammatory pain
-
COI: 1:CAS:528:DC%2BD2cXksFCnsLk%3D, PID: 14988418
-
Wang ZQ, Porreca F, Cuzzocrea S, Galen K, Lightfoot R, Masini E, et al. A newly identified role for superoxide in inflammatory pain. J Pharmacol Exp Ther. 2004;309:869–78.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 869-878
-
-
Wang, Z.Q.1
Porreca, F.2
Cuzzocrea, S.3
Galen, K.4
Lightfoot, R.5
Masini, E.6
-
11
-
-
54249160056
-
Increased production of mitochondrial superoxide in the spinal cord induces pain behaviors in mice: the effect of mitochondrial electron transport complex inhibitors
-
COI: 1:CAS:528:DC%2BD1cXht12ltr%2FJ, PID: 18832013
-
Kim HY, Chung JM, Chung K. Increased production of mitochondrial superoxide in the spinal cord induces pain behaviors in mice: the effect of mitochondrial electron transport complex inhibitors. Neurosci Lett. 2008;447:87–91.
-
(2008)
Neurosci Lett
, vol.447
, pp. 87-91
-
-
Kim, H.Y.1
Chung, J.M.2
Chung, K.3
-
12
-
-
0033863020
-
Nonsteroidal anti-inflammatory drug gastropathy
-
COI: 1:CAS:528:DC%2BD3cXmtVWru70%3D, PID: 10930388
-
Hawkey CJ. Nonsteroidal anti-inflammatory drug gastropathy. Gastroenterology. 2000;119:521–35.
-
(2000)
Gastroenterology
, vol.119
, pp. 521-535
-
-
Hawkey, C.J.1
-
13
-
-
84857711981
-
Toxicity of non-steroidal anti-inflammatory drugs: a review of melatonin and diclofenac sodium association
-
COI: 1:CAS:528:DC%2BC38XosFSiu74%3D, PID: 22374720
-
Aygun D, Kaplan S, Odaci E, Onger ME, Altunkaynak ME. Toxicity of non-steroidal anti-inflammatory drugs: a review of melatonin and diclofenac sodium association. Histol Histopathol. 2012;27:417–36.
-
(2012)
Histol Histopathol
, vol.27
, pp. 417-436
-
-
Aygun, D.1
Kaplan, S.2
Odaci, E.3
Onger, M.E.4
Altunkaynak, M.E.5
-
14
-
-
84856370253
-
Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults
-
COI: 1:CAS:528:DC%2BC38XhsFyhtb0%3D, PID: 22218162
-
McCullough ML, Peterson JJ, Patel R, Jacques PF, Shah R, Dwyer JT. Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults. Am J Clin Nutr. 2012;95:454–64.
-
(2012)
Am J Clin Nutr
, vol.95
, pp. 454-464
-
-
McCullough, M.L.1
Peterson, J.J.2
Patel, R.3
Jacques, P.F.4
Shah, R.5
Dwyer, J.T.6
-
15
-
-
59349120231
-
Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets
-
COI: 1:CAS:528:DC%2BD1MXhs1eisbw%3D, PID: 19110321
-
Aggarwal BB, Sung B. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. Trends Pharmacol Sci. 2009;30:85–94.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 85-94
-
-
Aggarwal, B.B.1
Sung, B.2
-
16
-
-
14144255339
-
Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2cXhtVGisL%2FE, PID: 15141484
-
Calabrese V, Butterfield DA, Stella AM. Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer’s disease. Ital J Biochem. 2003;52:177–81.
-
(2003)
Ital J Biochem
, vol.52
, pp. 177-181
-
-
Calabrese, V.1
Butterfield, D.A.2
Stella, A.M.3
-
17
-
-
0029591940
-
Antifungal activity of turmeric oil extracted from Curcuma longa (Zingiberaceae)
-
COI: 1:CAS:528:DyaK28XhsVShtbs%3D, PID: 8824742
-
Apisariyakul A, Vanittanakom N, Buddhasukh D. Antifungal activity of turmeric oil extracted from Curcuma longa (Zingiberaceae). J Ethnopharmacol. 1995;49:163–9.
-
(1995)
J Ethnopharmacol
, vol.49
, pp. 163-169
-
-
Apisariyakul, A.1
Vanittanakom, N.2
Buddhasukh, D.3
-
18
-
-
67449149681
-
Antiviral effect of Curcuma longa Linn extract against hepatitis B virus replication
-
PID: 19409970
-
Kim HJ, Yoo HS, Kim JC, Park CS, Choi MS, Kim M, et al. Antiviral effect of Curcuma longa Linn extract against hepatitis B virus replication. J Ethnopharmacol. 2009;124:189–96.
-
(2009)
J Ethnopharmacol
, vol.124
, pp. 189-196
-
-
Kim, H.J.1
Yoo, H.S.2
Kim, J.C.3
Park, C.S.4
Choi, M.S.5
Kim, M.6
-
19
-
-
84878276658
-
Ethnopharmacological and bioactivity guided investigation of five TCM anticancer herbs
-
COI: 1:CAS:528:DC%2BC3sXns1Knur4%3D, PID: 23623820
-
Meng QX, Roubin RH, Hanrahan JR. Ethnopharmacological and bioactivity guided investigation of five TCM anticancer herbs. J Ethnopharmacol. 2013;148:229–38.
-
(2013)
J Ethnopharmacol
, vol.148
, pp. 229-238
-
-
Meng, Q.X.1
Roubin, R.H.2
Hanrahan, J.R.3
-
20
-
-
0029023396
-
The anti-oxidant activity of turmeric (Curcuma longa)
-
COI: 1:CAS:528:DyaK2MXnt1CntbY%3D, PID: 7500637
-
Selvam R, Subramanian L, Gayathri R, Angayarkanni N. The anti-oxidant activity of turmeric (Curcuma longa). J Ethnopharmacol. 1995;47:59–67.
-
(1995)
J Ethnopharmacol
, vol.47
, pp. 59-67
-
-
Selvam, R.1
Subramanian, L.2
Gayathri, R.3
Angayarkanni, N.4
-
21
-
-
84874108793
-
Curcumin and aging
-
COI: 1:CAS:528:DC%2BC3sXjvVWqu7w%3D, PID: 23325575
-
Shen LR, Parnell LD, Ordovas JM, Lai CQ. Curcumin and aging. Biofactors. 2013;39:133–40.
-
(2013)
Biofactors
, vol.39
, pp. 133-140
-
-
Shen, L.R.1
Parnell, L.D.2
Ordovas, J.M.3
Lai, C.Q.4
-
22
-
-
4544236324
-
Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase
-
COI: 1:CAS:528:DC%2BD2cXntFaiurk%3D, PID: 15073046
-
Hong J, Bose M, Ju J, Ryu JH, Chen X, Sang S, et al. Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase. Carcinogenesis. 2004;25:1671–9.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1671-1679
-
-
Hong, J.1
Bose, M.2
Ju, J.3
Ryu, J.H.4
Chen, X.5
Sang, S.6
-
23
-
-
0033053430
-
Anti-metastatic activity of curcumin and catechin
-
COI: 1:CAS:528:DyaK1MXjs1Sjtrc%3D, PID: 10454257
-
Menon LG, Kuttan R, Kuttan G. Anti-metastatic activity of curcumin and catechin. Cancer Lett. 1999;141:159–65.
-
(1999)
Cancer Lett
, vol.141
, pp. 159-165
-
-
Menon, L.G.1
Kuttan, R.2
Kuttan, G.3
-
24
-
-
30044446136
-
Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation
-
COI: 1:CAS:528:DC%2BD28XktlWnsQ%3D%3D, PID: 16219905
-
Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol Pharmacol. 2006;69:195–206.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 195-206
-
-
Aggarwal, S.1
Ichikawa, H.2
Takada, Y.3
Sandur, S.K.4
Shishodia, S.5
Aggarwal, B.B.6
-
25
-
-
0032821829
-
Curcuma longa inhibits TNF-alpha induced expression of adhesion molecules on human umbilical vein endothelial cells
-
COI: 1:CAS:528:DyaK1MXnt1WlsL8%3D, PID: 10576620
-
Gupta B, Ghosh B. Curcuma longa inhibits TNF-alpha induced expression of adhesion molecules on human umbilical vein endothelial cells. Int J Immunopharmacol. 1999;21:745–57.
-
(1999)
Int J Immunopharmacol
, vol.21
, pp. 745-757
-
-
Gupta, B.1
Ghosh, B.2
-
26
-
-
0032520716
-
Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation
-
COI: 1:CAS:528:DyaK1cXitVKhurc%3D, PID: 9586949
-
Kumar A, Dhawan S, Hardegen NJ, Aggarwal BB. Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation. Biochem Pharmacol. 1998;55:775–83.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 775-783
-
-
Kumar, A.1
Dhawan, S.2
Hardegen, N.J.3
Aggarwal, B.B.4
-
27
-
-
84881291096
-
Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion
-
COI: 1:CAS:528:DC%2BC3sXht12itbjO, PID: 23871787
-
Gao S, Duan X, Wang X, Dong D, Liu D, Li X, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013;59:739–47.
-
(2013)
Food Chem Toxicol
, vol.59
, pp. 739-747
-
-
Gao, S.1
Duan, X.2
Wang, X.3
Dong, D.4
Liu, D.5
Li, X.6
-
28
-
-
84903525955
-
Anti-inflammatory potential of curcumin and quercetin in rats: Role of oxidative stress, heme oxygenase-1 and TNF-alpha
-
PID: 23024111
-
Heeba GH, Mahmoud ME, El Hanafy AA. Anti-inflammatory potential of curcumin and quercetin in rats: Role of oxidative stress, heme oxygenase-1 and TNF-alpha. Toxicol Ind Health 2012;30(6):551–60.
-
(2012)
Toxicol Ind Health
, vol.30
, Issue.6
, pp. 551-560
-
-
Heeba, G.H.1
Mahmoud, M.E.2
El Hanafy, A.A.3
-
29
-
-
79955411920
-
Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation
-
COI: 1:CAS:528:DC%2BC3MXjsVCksL0%3D, PID: 21413691
-
Cuomo J, Appendino G, Dern AS, Schneider E, McKinnon TP, Brown MJ, et al. Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. J Nat Prod. 2011;74:664–9.
-
(2011)
J Nat Prod
, vol.74
, pp. 664-669
-
-
Cuomo, J.1
Appendino, G.2
Dern, A.S.3
Schneider, E.4
McKinnon, T.P.5
Brown, M.J.6
-
30
-
-
79952253826
-
Efficacy and safety of Meriva(R), a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients
-
PID: 21194249
-
Belcaro G, Cesarone MR, Dugall M, Pellegrini L, Ledda A, Grossi MG, et al. Efficacy and safety of Meriva(R), a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev. 2010;15:337–44.
-
(2010)
Altern Med Rev
, vol.15
, pp. 337-344
-
-
Belcaro, G.1
Cesarone, M.R.2
Dugall, M.3
Pellegrini, L.4
Ledda, A.5
Grossi, M.G.6
-
31
-
-
84875359486
-
Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva((R))), nimesulide, and acetaminophen
-
PID: 23526055
-
Di Pierro F, Rapacioli G, Di Maio EA, Appendino G, Franceschi F, Togni S. Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva((R))), nimesulide, and acetaminophen. J Pain Res. 2013;6:201–5.
-
(2013)
J Pain Res
, vol.6
, pp. 201-205
-
-
Di Pierro, F.1
Rapacioli, G.2
Di Maio, E.A.3
Appendino, G.4
Franceschi, F.5
Togni, S.6
-
32
-
-
84902300218
-
Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva(R)): a randomised, placebo-controlled trial
-
PID: 24982601
-
Drobnic F, Riera J, Appendino G, Togni S, Franceschi F, Valle X, et al. Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva(R)): a randomised, placebo-controlled trial. J Int Soc Sports Nutr. 2014;11:31.
-
(2014)
J Int Soc Sports Nutr
, vol.11
, pp. 31
-
-
Drobnic, F.1
Riera, J.2
Appendino, G.3
Togni, S.4
Franceschi, F.5
Valle, X.6
-
33
-
-
84927730180
-
The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2
-
COI: 1:CAS:528:DC%2BC2MXhsVCmtbzE, PID: 25714890
-
Maioli NA, Zarpelon AC, Mizokami SS, Calixto-Campos C, Guazelli CF, Hohmann MS, et al. The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2. Braz J Med Biol Res. 2015;48(4):321–31.
-
(2015)
Braz J Med Biol Res
, vol.48
, Issue.4
, pp. 321-331
-
-
Maioli, N.A.1
Zarpelon, A.C.2
Mizokami, S.S.3
Calixto-Campos, C.4
Guazelli, C.F.5
Hohmann, M.S.6
-
34
-
-
1842450784
-
An electronic pressure-meter nociception paw test for mice
-
COI: 1:STN:280:DC%2BD2c7msFylug%3D%3D, PID: 15060710
-
Cunha TM, Verri WA Jr, Vivancos GG, Moreira IF, Reis S, Parada CA, et al. An electronic pressure-meter nociception paw test for mice. Braz J Med Biol Res. 2004;37:401–7.
-
(2004)
Braz J Med Biol Res
, vol.37
, pp. 401-407
-
-
Cunha, T.M.1
Verri, W.A.2
Vivancos, G.G.3
Moreira, I.F.4
Reis, S.5
Parada, C.A.6
-
35
-
-
16844365879
-
A novel hot-plate test sensitive to hyperalgesic stimuli and non-opioid analgesics
-
COI: 1:STN:280:DC%2BD2M7ivFKktA%3D%3D, PID: 15761625
-
Lavich TR, Cordeiro RS, Silva PM, Martins MA. A novel hot-plate test sensitive to hyperalgesic stimuli and non-opioid analgesics. Braz J Med Biol Res. 2005;38:445–51.
-
(2005)
Braz J Med Biol Res
, vol.38
, pp. 445-451
-
-
Lavich, T.R.1
Cordeiro, R.S.2
Silva, P.M.3
Martins, M.A.4
-
36
-
-
84888616759
-
5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality
-
PID: 24288682
-
Hohmann MS, Cardoso RD, Pinho-Ribeiro FA, Crespigio J, Cunha TM, Alves-Filho JC, et al. 5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality. Biomed Res Int. 2013;2013:627046.
-
(2013)
Biomed Res Int
, vol.2013
, pp. 627046
-
-
Hohmann, M.S.1
Cardoso, R.D.2
Pinho-Ribeiro, F.A.3
Crespigio, J.4
Cunha, T.M.5
Alves-Filho, J.C.6
-
37
-
-
51349102582
-
Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity
-
COI: 1:CAS:528:DC%2BD1cXhtV2rurrI, PID: 18497304
-
Ndengele MM, Cuzzocrea S, Esposito E, Mazzon E, Di Paola R, Matuschak GM, et al. Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity. FASEB J. 2008;22:3154–64.
-
(2008)
FASEB J
, vol.22
, pp. 3154-3164
-
-
Ndengele, M.M.1
Cuzzocrea, S.2
Esposito, E.3
Mazzon, E.4
Di Paola, R.5
Matuschak, G.M.6
-
38
-
-
33748704531
-
TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion
-
COI: 1:CAS:528:DC%2BD28XpvFekt7o%3D, PID: 16973155
-
Khattab MM. TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion. Eur J Pharmacol. 2006;548:167–73.
-
(2006)
Eur J Pharmacol
, vol.548
, pp. 167-173
-
-
Khattab, M.M.1
-
39
-
-
79551618617
-
The targets of curcumin
-
COI: 1:CAS:528:DC%2BC3MXisFOrsr8%3D, PID: 20955148
-
Zhou H, Beevers CS, Huang S. The targets of curcumin. Curr Drug Targets. 2011;12:332–47.
-
(2011)
Curr Drug Targets
, vol.12
, pp. 332-347
-
-
Zhou, H.1
Beevers, C.S.2
Huang, S.3
-
40
-
-
64549130895
-
Evaluation of antihyperalgesic effect of curcumin on formalin-induced orofacial pain in rat
-
COI: 1:CAS:528:DC%2BD1MXltVOls78%3D, PID: 19051211
-
Mittal N, Joshi R, Hota D, Chakrabarti A. Evaluation of antihyperalgesic effect of curcumin on formalin-induced orofacial pain in rat. Phytother Res. 2009;23:507–12.
-
(2009)
Phytother Res
, vol.23
, pp. 507-512
-
-
Mittal, N.1
Joshi, R.2
Hota, D.3
Chakrabarti, A.4
-
41
-
-
84875704973
-
Superoxide generation and leukocyte accumulation: key elements in the mediation of leukotriene B(4)-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1
-
COI: 1:CAS:528:DC%2BC3sXmtFegtLc%3D, PID: 23271050
-
Fernandes ES, Vong CT, Quek S, Cheong J, Awal S, Gentry C, et al. Superoxide generation and leukocyte accumulation: key elements in the mediation of leukotriene B(4)-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1. FASEB J. 2013;27:1664–73.
-
(2013)
FASEB J
, vol.27
, pp. 1664-1673
-
-
Fernandes, E.S.1
Vong, C.T.2
Quek, S.3
Cheong, J.4
Awal, S.5
Gentry, C.6
-
42
-
-
2342515377
-
Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin-induced orofacial nociception in rats
-
COI: 1:CAS:528:DC%2BD2cXjs1yht74%3D, PID: 15006904
-
Chichorro JG, Lorenzetti BB, Zampronio AR. Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin-induced orofacial nociception in rats. Br J Pharmacol. 2004;141:1175–84.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 1175-1184
-
-
Chichorro, J.G.1
Lorenzetti, B.B.2
Zampronio, A.R.3
-
43
-
-
34548101399
-
TRPA1 mediates formalin-induced pain
-
COI: 1:CAS:528:DC%2BD2sXps1eqsL8%3D, PID: 17686976
-
McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, Zhao M, et al. TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA. 2007;104:13525–30.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13525-13530
-
-
McNamara, C.R.1
Mandel-Brehm, J.2
Bautista, D.M.3
Siemens, J.4
Deranian, K.L.5
Zhao, M.6
-
44
-
-
80053246998
-
Curcumin ((E, E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1
-
COI: 1:CAS:528:DC%2BC3MXht1ans7nI, PID: 21855605
-
Leamy AW, Shukla P, McAlexander MA, Carr MJ, Ghatta S. Curcumin ((E, E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1. Neurosci Lett. 2011;503:157–62.
-
(2011)
Neurosci Lett
, vol.503
, pp. 157-162
-
-
Leamy, A.W.1
Shukla, P.2
McAlexander, M.A.3
Carr, M.J.4
Ghatta, S.5
-
45
-
-
0035815481
-
Electrolytic lesion of the anterior cingulate cortex decreases inflammatory, but not neuropathic nociceptive behavior in rats
-
COI: 1:CAS:528:DC%2BD3MXitF2rtbw%3D, PID: 11282366
-
Donahue RR, LaGraize SC, Fuchs PN. Electrolytic lesion of the anterior cingulate cortex decreases inflammatory, but not neuropathic nociceptive behavior in rats. Brain Res. 2001;897:131–8.
-
(2001)
Brain Res
, vol.897
, pp. 131-138
-
-
Donahue, R.R.1
LaGraize, S.C.2
Fuchs, P.N.3
-
46
-
-
0037964846
-
Independent time courses of supraspinal nociceptive activity and spinally mediated behavior during tonic pain
-
PID: 12855340
-
Porro CA, Cavazzuti M, Lui F, Giuliani D, Pellegrini M, Baraldi P. Independent time courses of supraspinal nociceptive activity and spinally mediated behavior during tonic pain. Pain. 2003;104:291–301.
-
(2003)
Pain
, vol.104
, pp. 291-301
-
-
Porro, C.A.1
Cavazzuti, M.2
Lui, F.3
Giuliani, D.4
Pellegrini, M.5
Baraldi, P.6
-
47
-
-
84872867676
-
Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism
-
COI: 1:CAS:528:DC%2BC3sXitlGqtrY%3D, PID: 23372844
-
Finley A, Chen Z, Esposito E, Cuzzocrea S, Sabbadini R, Salvemini D. Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism. PLoS One. 2013;8:e55255.
-
(2013)
PLoS One
, vol.8
, pp. e55255
-
-
Finley, A.1
Chen, Z.2
Esposito, E.3
Cuzzocrea, S.4
Sabbadini, R.5
Salvemini, D.6
-
48
-
-
84940877224
-
Myeloperoxidase Inhibitors as Potential Drugs
-
COI: 1:CAS:528:DC%2BC2MXhsFWmsLfL, PID: 26279325
-
Lazarevic-Pasti T, Leskovac A, Vasic V. Myeloperoxidase Inhibitors as Potential Drugs. Curr Drug Metab. 2015;16:168–90.
-
(2015)
Curr Drug Metab
, vol.16
, pp. 168-190
-
-
Lazarevic-Pasti, T.1
Leskovac, A.2
Vasic, V.3
-
49
-
-
54949147176
-
New regulators of NF-kappaB in inflammation
-
COI: 1:CAS:528:DC%2BD1cXht12isLfN, PID: 18927578
-
Ghosh S, Hayden MS. New regulators of NF-kappaB in inflammation. Nat Rev Immunol. 2008;8:837–48.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 837-848
-
-
Ghosh, S.1
Hayden, M.S.2
-
50
-
-
13544261749
-
Superoxide potentiates NF-kappaB activation and modulates endotoxin-induced cytokine production in alveolar macrophages
-
COI: 1:CAS:528:DC%2BD2MXktleltLw%3D, PID: 15665736
-
Ndengele MM, Muscoli C, Wang ZQ, Doyle TM, Matuschak GM, Salvemini D. Superoxide potentiates NF-kappaB activation and modulates endotoxin-induced cytokine production in alveolar macrophages. Shock. 2005;23:186–93.
-
(2005)
Shock
, vol.23
, pp. 186-193
-
-
Ndengele, M.M.1
Muscoli, C.2
Wang, Z.Q.3
Doyle, T.M.4
Matuschak, G.M.5
Salvemini, D.6
-
51
-
-
79960330994
-
Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kappaB inhibition
-
COI: 1:CAS:528:DC%2BC3MXptFais7w%3D, PID: 20643202
-
Oh SW, Cha JY, Jung JE, Chang BC, Kwon HJ, Lee BR, et al. Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kappaB inhibition. J Ethnopharmacol. 2011;136:414–21.
-
(2011)
J Ethnopharmacol
, vol.136
, pp. 414-421
-
-
Oh, S.W.1
Cha, J.Y.2
Jung, J.E.3
Chang, B.C.4
Kwon, H.J.5
Lee, B.R.6
-
52
-
-
58149343341
-
Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain
-
COI: 1:CAS:528:DC%2BD1cXht1Sgtr3J, PID: 18799680
-
Ibi M, Matsuno K, Shiba D, Katsuyama M, Iwata K, Kakehi T, et al. Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain. J Neurosci. 2008;28:9486–94.
-
(2008)
J Neurosci
, vol.28
, pp. 9486-9494
-
-
Ibi, M.1
Matsuno, K.2
Shiba, D.3
Katsuyama, M.4
Iwata, K.5
Kakehi, T.6
-
53
-
-
75649138334
-
Curcumin produces an antihyperalgesic effect via antagonism of TRPV1
-
COI: 1:CAS:528:DC%2BC3cXitVKhtb4%3D, PID: 20040737
-
Yeon KY, Kim SA, Kim YH, Lee MK, Ahn DK, Kim HJ, et al. Curcumin produces an antihyperalgesic effect via antagonism of TRPV1. J Dent Res. 2010;89:170–4.
-
(2010)
J Dent Res
, vol.89
, pp. 170-174
-
-
Yeon, K.Y.1
Kim, S.A.2
Kim, Y.H.3
Lee, M.K.4
Ahn, D.K.5
Kim, H.J.6
-
54
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
COI: 1:CAS:528:DC%2BC3cXhsFGgtrzE, PID: 21151103
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol. 2011;12:222–30.
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
-
55
-
-
84919622559
-
The ruthenium nitric oxide donor, [Ru(HEDTA)NO], inhibits acute nociception in mice by modulating oxidative stress, cytokine production and activating the cGMP/PKG/ATP-sensitive potassium channel signaling pathway
-
COI: 1:CAS:528:DC%2BC2cXhtlCitr%2FP, PID: 25116441
-
Staurengo-Ferrari L, Mizokami SS, Fattori V, Silva JJ, Zanichelli PG, Georgetti SR, et al. The ruthenium nitric oxide donor, [Ru(HEDTA)NO], inhibits acute nociception in mice by modulating oxidative stress, cytokine production and activating the cGMP/PKG/ATP-sensitive potassium channel signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2014;387(11):1053–68.
-
(2014)
Naunyn Schmiedebergs Arch Pharmacol
, vol.387
, Issue.11
, pp. 1053-1068
-
-
Staurengo-Ferrari, L.1
Mizokami, S.S.2
Fattori, V.3
Silva, J.J.4
Zanichelli, P.G.5
Georgetti, S.R.6
-
56
-
-
73349137314
-
Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production
-
COI: 1:CAS:528:DC%2BD1MXhtlyrsLfK, PID: 19899776
-
Valerio DA, Georgetti SR, Magro DA, Casagrande R, Cunha TM, Vicentini FT, et al. Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production. J Nat Prod. 2009;72:1975–9.
-
(2009)
J Nat Prod
, vol.72
, pp. 1975-1979
-
-
Valerio, D.A.1
Georgetti, S.R.2
Magro, D.A.3
Casagrande, R.4
Cunha, T.M.5
Vicentini, F.T.6
-
57
-
-
33745067467
-
Immediate and delayed treatments with curcumin prevents forebrain ischemia-induced neuronal damage and oxidative insult in the rat hippocampus
-
COI: 1:CAS:528:DC%2BD28XlsFCjt7c%3D, PID: 16770732
-
Al-Omar FA, Nagi MN, Abdulgadir MM, Al Joni KS, Al-Majed AA. Immediate and delayed treatments with curcumin prevents forebrain ischemia-induced neuronal damage and oxidative insult in the rat hippocampus. Neurochem Res. 2006;31:611–8.
-
(2006)
Neurochem Res
, vol.31
, pp. 611-618
-
-
Al-Omar, F.A.1
Nagi, M.N.2
Abdulgadir, M.M.3
Al Joni, K.S.4
Al-Majed, A.A.5
-
58
-
-
84925512235
-
Curcumin attenuates CFA induced thermal hyperalgesia by modulation of antioxidant enzymes and down regulation of TNF-alpha, IL-1beta and IL-6
-
COI: 1:CAS:528:DC%2BC2cXitVGls7zE, PID: 25479948
-
Singh AK, Vinayak M. Curcumin attenuates CFA induced thermal hyperalgesia by modulation of antioxidant enzymes and down regulation of TNF-alpha, IL-1beta and IL-6. Neurochem Res. 2015;40:463–72.
-
(2015)
Neurochem Res
, vol.40
, pp. 463-472
-
-
Singh, A.K.1
Vinayak, M.2
-
59
-
-
45849115079
-
Antioxidant and radical scavenging properties of curcumin
-
COI: 1:CAS:528:DC%2BD1cXnvVKgurc%3D, PID: 18547552
-
Ak T, Gulcin I. Antioxidant and radical scavenging properties of curcumin. Chem Biol Interact. 2008;174:27–37.
-
(2008)
Chem Biol Interact
, vol.174
, pp. 27-37
-
-
Ak, T.1
Gulcin, I.2
-
60
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
COI: 1:CAS:528:DC%2BD3cXjvFaisbc%3D, PID: 10821856
-
Ishii T, Itoh K, Takahashi S, Sato H, Yanagawa T, Katoh Y, et al. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem. 2000;275:16023–9.
-
(2000)
J Biol Chem
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
Sato, H.4
Yanagawa, T.5
Katoh, Y.6
-
61
-
-
84905107800
-
Protective effect of coconut water concentrate and its active component shikimic acid against hydroperoxide mediated oxidative stress through suppression of NF-kappaB and activation of Nrf2 pathway
-
COI: 1:CAS:528:DC%2BC2cXhtVWrs7nM, PID: 24835026
-
Manna K, Khan A, Kr Das D, Bandhu Kesh S, Das U, Ghosh S, et al. Protective effect of coconut water concentrate and its active component shikimic acid against hydroperoxide mediated oxidative stress through suppression of NF-kappaB and activation of Nrf2 pathway. J Ethnopharmacol. 2014;155:132–46.
-
(2014)
J Ethnopharmacol
, vol.155
, pp. 132-146
-
-
Manna, K.1
Khan, A.2
Kr Das, D.3
Bandhu Kesh, S.4
Das, U.5
Ghosh, S.6
-
62
-
-
77958150583
-
Role of heme oxygenase in preserving vascular bioactive NO
-
COI: 1:CAS:528:DC%2BC3cXhtlequrnP, PID: 20713168
-
Pae HO, Son Y, Kim NH, Jeong HJ, Chang KC, Chung HT. Role of heme oxygenase in preserving vascular bioactive NO. Nitric Oxide. 2010;23:251–7.
-
(2010)
Nitric Oxide
, vol.23
, pp. 251-257
-
-
Pae, H.O.1
Son, Y.2
Kim, N.H.3
Jeong, H.J.4
Chang, K.C.5
Chung, H.T.6
-
63
-
-
41949141296
-
NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK
-
COI: 1:CAS:528:DC%2BD1cXkvVOgsrk%3D, PID: 18241676
-
Liu GH, Qu J, Shen X. NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK. Biochim Biophys Acta. 2008;1783:713–27.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 713-727
-
-
Liu, G.H.1
Qu, J.2
Shen, X.3
-
64
-
-
4844219758
-
Bilirubin: an endogenous product of heme degradation with both cytotoxic and cytoprotective properties
-
COI: 1:CAS:528:DC%2BD2cXotlGmt70%3D, PID: 15269289
-
Kapitulnik J. Bilirubin: an endogenous product of heme degradation with both cytotoxic and cytoprotective properties. Mol Pharmacol. 2004;66:773–9.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 773-779
-
-
Kapitulnik, J.1
-
65
-
-
84878164869
-
The nitroxyl donor, Angeli’s salt, inhibits inflammatory hyperalgesia in rats
-
COI: 1:CAS:528:DC%2BC3sXoslajsb4%3D, PID: 23541720
-
Zarpelon AC, Souza GR, Cunha TM, Schivo IR, Marchesi M, Casagrande R, et al. The nitroxyl donor, Angeli’s salt, inhibits inflammatory hyperalgesia in rats. Neuropharmacology. 2013;71:1–9.
-
(2013)
Neuropharmacology
, vol.71
, pp. 1-9
-
-
Zarpelon, A.C.1
Souza, G.R.2
Cunha, T.M.3
Schivo, I.R.4
Marchesi, M.5
Casagrande, R.6
-
66
-
-
84907164517
-
Treatment with a heme oxygenase 1 inducer enhances the antinociceptive effects of micro-opioid, delta-opioid, and cannabinoid 2 receptors during inflammatory pain
-
PID: 25204546
-
Carcole M, Castany S, Leanez S, Pol O. Treatment with a heme oxygenase 1 inducer enhances the antinociceptive effects of micro-opioid, delta-opioid, and cannabinoid 2 receptors during inflammatory pain. J Pharmacol Exp Ther. 2014;351:224–32.
-
(2014)
J Pharmacol Exp Ther
, vol.351
, pp. 224-232
-
-
Carcole, M.1
Castany, S.2
Leanez, S.3
Pol, O.4
-
67
-
-
0035036498
-
Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity
-
COI: 1:CAS:528:DC%2BD3MXjt1arsLc%3D, PID: 11309238
-
Steiner AA, Branco LG, Cunha FQ, Ferreira SH. Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity. Br J Pharmacol. 2001;132:1673–82.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1673-1682
-
-
Steiner, A.A.1
Branco, L.G.2
Cunha, F.Q.3
Ferreira, S.H.4
-
68
-
-
77649189669
-
Curcumin alleviates ethanol-induced hepatocytes oxidative damage involving heme oxygenase-1 induction
-
COI: 1:CAS:528:DC%2BC3cXjtVCru7k%3D, PID: 20080166
-
Bao W, Li K, Rong S, Yao P, Hao L, Ying C, et al. Curcumin alleviates ethanol-induced hepatocytes oxidative damage involving heme oxygenase-1 induction. J Ethnopharmacol. 2010;128:549–53.
-
(2010)
J Ethnopharmacol
, vol.128
, pp. 549-553
-
-
Bao, W.1
Li, K.2
Rong, S.3
Yao, P.4
Hao, L.5
Ying, C.6
-
69
-
-
84929028500
-
Interleukin-10 limits intense acute swimming-induced muscle mechanical hyperalgesia in mice
-
COI: 1:CAS:528:DC%2BC2MXotVektbc%3D, PID: 25711612
-
Borghi SM, Pinho-Ribeiro FA, Zarpelon AC, Cunha TM, Alves-Filho JC, Ferreira SH, et al. Interleukin-10 limits intense acute swimming-induced muscle mechanical hyperalgesia in mice. Exp Physiol. 2015;100(5):531–44.
-
(2015)
Exp Physiol
, vol.100
, Issue.5
, pp. 531-544
-
-
Borghi, S.M.1
Pinho-Ribeiro, F.A.2
Zarpelon, A.C.3
Cunha, T.M.4
Alves-Filho, J.C.5
Ferreira, S.H.6
-
70
-
-
34548618130
-
Exercise decreases oxidative stress and inflammation and restores renal dopamine D1 receptor function in old rats
-
COI: 1:CAS:528:DC%2BD2sXhtVOqt7bN, PID: 17634393
-
Asghar M, George L, Lokhandwala MF. Exercise decreases oxidative stress and inflammation and restores renal dopamine D1 receptor function in old rats. Am J Physiol Renal Physiol. 2007;293:F914–9.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F914-F919
-
-
Asghar, M.1
George, L.2
Lokhandwala, M.F.3
-
71
-
-
67349214659
-
Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages
-
COI: 1:CAS:528:DC%2BD1MXntVKjsbg%3D, PID: 19376150
-
Woods CG, Fu J, Xue P, Hou Y, Pluta LJ, Yang L, et al. Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages. Toxicol Appl Pharmacol. 2009;238:27–36.
-
(2009)
Toxicol Appl Pharmacol
, vol.238
, pp. 27-36
-
-
Woods, C.G.1
Fu, J.2
Xue, P.3
Hou, Y.4
Pluta, L.J.5
Yang, L.6
-
72
-
-
0036127426
-
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
-
COI: 1:CAS:528:DC%2BD38Xit1equ70%3D, PID: 11875494
-
Lee TS, Chau LY. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med. 2002;8:240–6.
-
(2002)
Nat Med
, vol.8
, pp. 240-246
-
-
Lee, T.S.1
Chau, L.Y.2
|