Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1

Neuroscience Letters

Volumn 503, Issue 3, 2011, Pages 157-162

  Leamy, Andrew W ^a   Shukla, Praveen ^a,b   McAlexander, Michael A ^a   Carr, Michael J ^a   Ghatta, Srinivas ^a  

^a GLAXOSMITHKLINE   (United States)

^b NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Curcumin; Desensitization; Mouse vagal neurons; Transient receptor potential A1 (TRPA1); Whole cell voltage clamp

Indexed keywords

CALCIUM; CURCUMIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; VANILLOID RECEPTOR 1;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DESENSITIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TACHYPHYLAXIS; VAGUS NERVE; VOLTAGE CLAMP; WHOLE CELL;

ANIMALS; CALCIUM; CAPSAICIN; CURCUMIN; DATA INTERPRETATION, STATISTICAL; EXTRACELLULAR SPACE; HEK293 CELLS; HUMANS; MICE; MICE, KNOCKOUT; PATCH-CLAMP TECHNIQUES; PROSTAGLANDIN D2; SENSORY RECEPTOR CELLS; TACHYPHYLAXIS; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPM CATION CHANNELS; VAGUS NERVE;

EID: 80053246998     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.07.054     Document Type: Article

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