Superoxide potentiates NF-κB activation and modulates endotoxin-induced cytokine production in alveolar macrophages

Shock

Volumn 23, Issue 2, 2005, Pages 186-193

  Ndengele, Michael M ^a   Muscoli, Carolina ^b   Wang, Zhi Qiang ^a   Doyle, Timothy M ^c   Matuschak, George M ^c   Salvemini, Daniela ^a  

^a MetaPhore Pharmaceuticals   (United States)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute lung injury; ARDS; Interleukin 6; SODm; TNF

Indexed keywords

CYTOKINE; ENDOTOXIN; HYDROETHIDINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MANGANESEDICHLORO(3,10,13,20,26 PENTAAZATETRACYCLO[20.3.1.0(4,9).0(14,19)] 1(26),22(23),24 HEXACOSATRIENE); REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; SYNAPTOTAGMIN; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL INFECTION; BIOSYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRITICAL ILLNESS; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE OVEREXPRESSION; GRAM NEGATIVE BACTERIUM; LOWER RESPIRATORY TRACT; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MONOCYTE; MULTIPLE ORGAN FAILURE; NONHUMAN; OXIDATION; PATHOGENESIS; PROTEIN DEGRADATION; RAT; REDUCTION; REGULATORY MECHANISM; SEPTIC SHOCK; TRANSACTIVATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; COLORING AGENTS; CYTOKINES; CYTOPLASM; ENDOTOXINS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; I-KAPPA B PROTEINS; IMMUNOBLOTTING; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MACROPHAGES; MACROPHAGES, ALVEOLAR; MANGANESE; MODELS, BIOLOGICAL; NF-KAPPA B; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; OXYGEN; PHENANTHRIDINES; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SUPEROXIDES; TIME FACTORS; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 13544261749     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000144130.36771.d6     Document Type: Article

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