The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2

Brazilian Journal of Medical and Biological Research

Volumn 48, Issue 4, 2015, Pages 321-331

  Maioli, N A ^a   Zarpelon, A C ^a   Mizokami, S S ^a   Calixto Campos, C ^a   Guazelli, C F S ^a   Hohmann, M S N ^a   Pinho Ribeiro, F A ^a   Carvalho, T T ^a   Manchope, M F ^a   Ferraz, C R ^a   Casagrande, R ^a   Verri, W A ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

Author keywords

Inflammation; Oxidative stress; Pain; Potassium superoxide; Superoxide anion

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; GLUTATHIONE; MESSENGER RNA; MORPHINE; MYELOPEROXIDASE; NALOXONE; QUERCETIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; ANTIOXIDANT; CYCLOOXYGENASE 2 INHIBITOR; NARCOTIC ANALGESIC AGENT; PEROXIDASE; POTASSIUM SUPEROXIDE;

ABTS RADICAL SCAVENGING ASSAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; EXPERIMENTAL DISEASE; HOT PLATE TEST; HYPERALGESIA; LEUKOCYTE COUNT; LONG DURATION STIMULUS TEST; MALE; MOUSE; NOCICEPTION; NONHUMAN; OXIDATIVE STRESS; PAW EDEMA; PAW FLINCHES TEST; PERITONEAL CAVITY; POTASSIUM SUPEROXIDE INDUCED INFLAMMATION; POTASSIUM SUPEROXIDE INDUCED PAIN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TIME SPENT LICKING TEST; WRITHING TEST; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; EDEMA; GENETIC TRANSCRIPTION; GENETICS; HEAT; HINDLIMB; INFLAMMATION; METABOLISM; NOCICEPTIVE PAIN; PAIN MEASUREMENT; PROCEDURES; SKIN; TIME;

MUS;

ANALGESICS, OPIOID; ANIMALS; ANTIOXIDANTS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; EDEMA; HINDLIMB; HOT TEMPERATURE; HYPERALGESIA; INFLAMMATION; MALE; MICE; NOCICEPTIVE PAIN; PAIN MEASUREMENT; PEROXIDASE; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; SKIN; SUPEROXIDES; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 84927730180     PISSN: None     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/1414-431X20144187     Document Type: Article

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