TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation

Nature Immunology

Volumn 16, Issue 11, 2015, Pages 1195-1203

  Wang, Xu Dong ^a   Gong, Yu ^a   Chen, Zhi Long ^a   Gong, Bei Ni ^a   Xie, Ji Ji ^a,b   Zhong, Chuan Qi ^c   Wang, Qi Long ^a   Diao, Liang Hui ^a   Xu, Anlong ^a   Han, Jiahuai ^c   Altman, Amnon ^b   Li, Yingqiu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c XIAMEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; FILAMIN A; INTERLEUKIN 2; PROTEIN KINASE C THETA; T LYMPHOCYTE RECEPTOR; FILAMIN; ISOENZYME; LYMPHOCYTE ANTIGEN RECEPTOR; LYSINE; PIAS2 PROTEIN, HUMAN; PRKCQ PROTEIN, HUMAN; PRKCQ PROTEIN, MOUSE; PROTEIN INHIBITOR OF ACTIVATED STAT; PROTEIN KINASE C;

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SUMOYLATION; T LYMPHOCYTE ACTIVATION; TANDEM MASS SPECTROMETRY; TH2 CELL; ANIMAL; BINDING SITE; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DEFICIENCY; ENZYMOLOGY; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; JURKAT CELL LINE; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; SITE DIRECTED MUTAGENESIS; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD28; BINDING SITES; CELL DIFFERENTIATION; CELLS, CULTURED; FILAMINS; HEK293 CELLS; HUMANS; IMMUNOLOGICAL SYNAPSES; ISOENZYMES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYSINE; MICE; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; PROTEIN INHIBITORS OF ACTIVATED STAT; PROTEIN KINASE C; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SUMOYLATION; T-LYMPHOCYTES; TH2 CELLS;

EID: 84945448158     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3259     Document Type: Article

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