-
1
-
-
64049108784
-
The cellular context of T cell signaling
-
Dustin, M.L. The cellular context of T cell signaling. Immunity 30, 482-492 (2009).
-
(2009)
Immunity
, vol.30
, pp. 482-492
-
-
Dustin, M.L.1
-
3
-
-
0031012266
-
Selective modulation of protein kinase C-θ during T-cell activation
-
DOI 10.1038/385083a0
-
Monks, C.R., Kupfer, H., Tamir, I., Barlow, A. & Kupfer, A. Selective modulation of protein kinase C-θ during T-cell activation. Nature 385, 83-86 (1997). (Pubitemid 27024559)
-
(1997)
Nature
, vol.385
, Issue.6611
, pp. 83-86
-
-
Monks, C.R.F.1
Kupfer, H.2
Tamir, I.3
Barlow, A.4
Kupfer, A.5
-
4
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
DOI 10.1038/25764
-
Monks, C.R., Freiberg, B.A., Kupfer, H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998). (Pubitemid 28420234)
-
(1998)
Nature
, vol.395
, Issue.6697
, pp. 82-86
-
-
Monks, C.R.F.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
5
-
-
0038620475
-
2+ mobilization and NFAT cell activation in primary mouse T cells
-
DOI 10.1084/jem.20020234
-
Pfeifhofer, C. et al. Protein kinase C θ affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells. J. Exp. Med. 197, 1525-1535 (2003). (Pubitemid 36682549)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.11
, pp. 1525-1535
-
-
Pfeifhofer, C.1
Kofler, K.2
Gruber, T.3
Ghaffari Tabrizi, N.4
Lutz, C.5
Maly, K.6
Leitges, M.7
Baier, G.8
-
6
-
-
18844473151
-
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
-
DOI 10.1038/35006090
-
Sun, Z. et al. PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes. Nature 404, 402-407 (2000). (Pubitemid 30164343)
-
(2000)
Nature
, vol.404
, Issue.6776
, pp. 402-407
-
-
Sun, Z.1
Arendt, C.W.2
Ellmeier, W.3
Schaeffer, E.M.4
Sunshine, M.J.5
Gandhl, L.6
Annes, J.7
Petrzilka, D.8
Kupfer, A.9
Schwartzberg, P.L.10
Littman, D.R.11
-
7
-
-
34250692040
-
Protein kinase C theta (PKCθ): A key player in T cell life and death
-
DOI 10.1016/j.phrs.2007.04.009, PII S1043661807000898
-
Hayashi, K. & Altman, A. Protein kinase C θ (PKCθ): a key player in T cell life and death. Pharmacol. Res. 55, 537-544 (2007). (Pubitemid 46962308)
-
(2007)
Pharmacological Research
, vol.55
, Issue.6
, pp. 537-544
-
-
Hayashi, K.1
Altman, A.2
-
8
-
-
0034724201
-
NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-θ
-
DOI 10.1073/pnas.060028097
-
Coudronniere, N., Villalba, M., Englund, N. & Altman, A. NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-θ. Proc. Natl. Acad. Sci. USA 97, 3394-3399 (2000). (Pubitemid 30183313)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3394-3399
-
-
Coudronniere, N.1
Villalba, M.2
Englund, N.3
Altman, A.4
-
9
-
-
0029670089
-
Protein kinase C-θ isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes
-
Baier-Bitterlich, G. et al. Protein kinase C-θ isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes. Mol. Cell. Biol. 16, 1842-1850 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1842-1850
-
-
Baier-Bitterlich, G.1
-
10
-
-
3042645122
-
2+ signaling by PKCθ in restimulated T cells via a Tec kinase-dependent pathway
-
DOI 10.1002/eji.200324625
-
Altman, A. et al. Positive feedback regulation of PLCγ1/Ca2+ signaling by PKCθ in restimulated T cells via a Tec kinase-dependent pathway. Eur. J. Immunol. 34, 2001-2011 (2004). (Pubitemid 39256081)
-
(2004)
European Journal of Immunology
, vol.34
, Issue.7
, pp. 2001-2011
-
-
Altman, A.1
Kaminski, S.2
Busuttil, V.3
Droin, N.4
Hu, J.5
Tadevosyan, Y.6
Hipskind, R.A.7
Villalba, M.8
-
11
-
-
0034031401
-
Protein kinase C-θ Participates in NF-κB activation induced by CD3- CD28 costimulation through selective activation of IκB kinase β
-
DOI 10.1128/MCB.20.8.2933-2940.2000
-
Lin, X., O'Mahony, A., Geleziunas, R. & Greene, W.C. Protein kinase C θ participates in NF-κB/Rel activation induced by CD3/CD28 costimulation through selective activation of IκB β (IKKβ). Mol. Cell. Biol. 20, 2933-2940 (2000). (Pubitemid 30183513)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.8
, pp. 2933-2940
-
-
Lin, X.1
O'Mahony, A.2
Mu, Y.3
Geleziunas, R.4
Greene, W.C.5
-
12
-
-
28944445460
-
Differential roles of PKC-θ in the regulation of intracellular calcium concentration in primary T cells
-
DOI 10.1016/j.jmb.2005.10.043, PII S0022283605012878
-
Manicassamy, S., Sadim, M., Ye, R.D. & Sun, Z. Differential roles of PKC-θ in the regulation of intracellular calcium concentration in primary T cells. J. Mol. Biol. 355, 347-359 (2006). (Pubitemid 41785743)
-
(2006)
Journal of Molecular Biology
, vol.355
, Issue.3
, pp. 347-359
-
-
Manicassamy, S.1
Sadim, M.2
Ye, R.D.3
Sun, Z.4
-
13
-
-
3242790172
-
Protein kinase C θ is critical for the development of in vivo T helper (Th)2 cell but not Th-1 cell responses
-
DOI 10.1084/jem.20032229
-
Marsland, B.J., Soos, T.J., Spath, G., Littman, D.R. & Kopf, M. Protein kinase C θ is critical for the development of in vivo T helper Th2 cell but not Th1 cell responses. J. Exp. Med. 200, 181-189 (2004). (Pubitemid 38982177)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.2
, pp. 181-189
-
-
Marsland, B.J.1
Soos, T.J.2
Spath, G.3
Littman, D.R.4
Kopf, M.5
-
14
-
-
8444243253
-
Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase Cθ
-
Salek-Ardakani, S., So, T., Halteman, B.S., Altman, A. & Croft, M. Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C θ. J. Immunol. 173, 6440-6447 (2004). (Pubitemid 39487805)
-
(2004)
Journal of Immunology
, vol.173
, Issue.10
, pp. 6440-6447
-
-
Salek-Ardakani, S.1
So, T.2
Halteman, B.S.3
Altman, A.4
Croft, M.5
-
15
-
-
28244464872
-
Protein kinase Cθ controls Th1 cells in experimental autoimmune encephalomyelitis
-
Salek-Ardakani, S., So, T., Halteman, B.S., Altman, A. & Croft, M. Protein kinase Cθ controls Th1 cells in experimental autoimmune encephalomyelitis. J. Immunol. 175, 7635-7641 (2005). (Pubitemid 41713463)
-
(2005)
Journal of Immunology
, vol.175
, Issue.11
, pp. 7635-7641
-
-
Salek-Ardakani, S.1
So, T.2
Halteman, B.S.3
Altman, A.4
Croft, M.5
-
16
-
-
33750036982
-
Mice deficient in PKC theta demonstrate impaired in vivo T cell activation and protection from T cell-mediated inflammatory diseases
-
DOI 10.1080/08916930600907954, PII U0H3464830345134
-
Anderson, K. et al. Mice deficient in PKC θ demonstrate impaired in vivo T cell activation and protection from T cell-mediated inflammatory diseases. Autoimmunity 39, 469-478 (2006). (Pubitemid 44575079)
-
(2006)
Autoimmunity
, vol.39
, Issue.6
, pp. 469-478
-
-
Anderson, K.1
Fitzgerald, M.2
DuPont, M.3
Wang, T.4
Paz, N.5
Dorsch, M.6
Healy, A.7
Xu, Y.8
Ocain, T.9
Schopf, L.10
Jaffee, B.11
Picarella, D.12
-
17
-
-
33644512418
-
Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C θ-deficient mice
-
Tan, S.L. et al. Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C θ-deficient mice. J. Immunol. 176, 2872-2879 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 2872-2879
-
-
Tan, S.L.1
-
18
-
-
1642299050
-
PKCθ Signals Activation versus Tolerance In Vivo
-
DOI 10.1084/jem.20031022
-
Berg-Brown, N.N. et al. PKCθ signals activation versus tolerance in vivo. J. Exp. Med. 199, 743-752 (2004). (Pubitemid 38375194)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.6
, pp. 743-752
-
-
Berg-Brown, N.N.1
Gronski, M.A.2
Jones, R.G.3
Elford, A.R.4
Deenick, E.K.5
Odermatt, B.6
Littman, D.R.7
Ohashi, P.S.8
-
19
-
-
18744364178
-
Protein kinase C θ is not essential for T-cell-mediated clearance of murine gammaherpesvirus 68
-
DOI 10.1128/JVI.79.11.6808-6813.2005
-
Giannoni, F., Lyon, A.B., Wareing, M.D., Dias, P.B. & Sarawar, S.R. Protein kinase C θ is not essential for T-cell-mediated clearance of murine gammaherpesvirus 68. J. Virol. 79, 6808-6813 (2005). (Pubitemid 40677313)
-
(2005)
Journal of Virology
, vol.79
, Issue.11
, pp. 6808-6813
-
-
Giannoni, F.1
Lyon, A.B.2
Wareing, M.D.3
Dias, P.B.4
Sarawar, S.R.5
-
20
-
-
26444476013
-
Innate signals compensate for the absence of PKC-θ during in vivo CD8+ T cell effector and memory responses
-
DOI 10.1073/pnas.0506250102
-
Marsland, B.J. et al. Innate signals compensate for the absence of PKCθ during in vivo CD8+ T cell effector and memory responses. Proc. Natl. Acad. Sci. USA 102, 14374-14379 (2005). (Pubitemid 41429705)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.40
, pp. 14374-14379
-
-
Marsland, B.J.1
Nembrini, C.2
Schmitz, N.3
Abel, B.4
Krautwald, S.5
Bachmann, M.F.6
Kopf, M.7
-
21
-
-
33947204489
-
TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-θ signaling and promote autoimmune myocarditis
-
Marsland, B.J. et al. TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-θ signaling and promote autoimmune myocarditis. J. Immunol. 178, 3466-3473 (2007). (Pubitemid 46417611)
-
(2007)
Journal of Immunology
, vol.178
, Issue.6
, pp. 3466-3473
-
-
Marsland, B.J.1
Nembrini, C.2
Grun, K.3
Reissmann, R.4
Kurrer, M.5
Leipner, C.6
Kopf, M.7
-
22
-
-
72849123229
-
PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice
-
Valenzuela, J.O. et al. PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice. J. Clin. Invest. 119, 3774-3786 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3774-3786
-
-
Valenzuela, J.O.1
-
23
-
-
0030611049
-
2+ differentially regulates conventional protein kinase Cs' membrane interaction and activation
-
DOI 10.1074/jbc.272.41.25959
-
Keranen, L.M. & Newton, A.C. Ca2+ differentially regulates conventional protein kinase Cs′ membrane interaction and activation. J. Biol. Chem. 272, 25959-25967 (1997). (Pubitemid 27438923)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.41
, pp. 25959-25967
-
-
Keranen, L.M.1
Newton, A.C.2
-
24
-
-
0033987234
-
TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway
-
DOI 10.1002/15 21-4141(200 001)30:1<50::A ID-IMMU 50>3.0.CO;2-I
-
Huang, J., Sugie, K., La Face, D.M., Altman, A. & Grey, H.M. TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway. Eur. J. Immunol. 30, 50-58 (2000). (Pubitemid 30011765)
-
(2000)
European Journal of Immunology
, vol.30
, Issue.1
, pp. 50-58
-
-
Huang, J.1
Sugie, K.2
La Face, D.M.3
Altman, A.4
Grey, H.M.5
-
25
-
-
58149280838
-
T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C θ
-
Tseng, S.Y., Waite, J.C., Liu, M., Vardhana, S. & Dustin, M.L. T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C θ. J. Immunol. 181, 4852-4863 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 4852-4863
-
-
Tseng, S.Y.1
Waite, J.C.2
Liu, M.3
Vardhana, S.4
Dustin, M.L.5
-
26
-
-
54949103906
-
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C θ translocation
-
Yokosuka, T. et al. Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C θ translocation. Immunity 29, 589-601 (2008).
-
(2008)
Immunity
, vol.29
, pp. 589-601
-
-
Yokosuka, T.1
-
27
-
-
34547118860
-
Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase C
-
DOI 10.1074/jbc.M700119200
-
Melowic, H.R. et al. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cθ. J. Biol. Chem. 282, 21467-21476 (2007). (Pubitemid 47099967)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.29
, pp. 21467-21476
-
-
Melowic, H.R.1
Stahelin, R.V.2
Blatner, N.R.3
Tian, W.4
Hayashi, K.5
Altman, A.6
Cho, W.7
-
28
-
-
0033950079
-
The importance of being proline: The interaction of proline-rich motifs in signaling proteins with their cognate domains
-
Kay, B.K., Williamson, M.P. & Sudol, M. The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. FASEB J. 14, 231-241 (2000). (Pubitemid 30086060)
-
(2000)
FASEB Journal
, vol.14
, Issue.2
, pp. 231-241
-
-
Kay, B.K.1
Williamson, M.P.2
Sudol, M.3
-
29
-
-
67650072922
-
Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation
-
Dodson, L.F. et al. Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation. Mol. Cell. Biol. 29, 3710-3721 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3710-3721
-
-
Dodson, L.F.1
-
30
-
-
72449184637
-
Two pathways of costimulation through CD28
-
Miller, J. et al. Two pathways of costimulation through CD28. Immunol. Res. 45, 159-172 (2009).
-
(2009)
Immunol. Res.
, vol.45
, pp. 159-172
-
-
Miller, J.1
-
31
-
-
10344237020
-
Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signalling pathways
-
Sanchez-Lockhart, M. et al. Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways. J. Immunol. 173, 7120-7124 (2004). (Pubitemid 39628145)
-
(2004)
Journal of Immunology
, vol.173
, Issue.12
, pp. 7120-7124
-
-
Sanchez-Lockhart, M.1
Marin, E.2
Graf, B.3
Abe, R.4
Harada, Y.5
Sedwick, C.E.6
Miller, J.7
-
32
-
-
0033558276
-
Identification of tyrosine phosphorylation sites in the CD28 cytoplasmic domain and their role in the costimulation of Jurkat T cells
-
Sadra, A. et al. Identification of tyrosine phosphorylation sites in the CD28 cytoplasmic domain and their role in the costimulation of Jurkat T cells. J. Immunol. 162, 1966-1973 (1999). (Pubitemid 29288813)
-
(1999)
Journal of Immunology
, vol.162
, Issue.4
, pp. 1966-1973
-
-
Sadra, A.1
Cinek, T.2
Arellano, J.L.3
Shi, J.4
Truitt, K.E.5
Imboden, J.B.6
-
33
-
-
15444373759
-
Multiple modes of interaction between Lck and CD28 [2] (multiple letters)
-
Hofinger, E. & Sticht, H. Multiple modes of interaction between Lck and CD28. J. Immunol. 174, 3839-3840 (2005). (Pubitemid 40395954)
-
(2005)
Journal of Immunology
, vol.174
, Issue.7
, pp. 3839-3840
-
-
Hofinger, E.1
Sticht, H.2
Tavano, R.3
Viola, A.4
-
34
-
-
0034602963
-
Regulation of protein kinase Cθ function during T cell activation by Lck-mediated tyrosine phosphorylation
-
DOI 10.1074/jbc.275.5.3603
-
Liu, Y. et al. Regulation of protein kinase Cθ function during T cell activation by Lck-mediated tyrosine phosphorylation. J. Biol. Chem. 275, 3603-3609 (2000). (Pubitemid 30083070)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.5
, pp. 3603-3609
-
-
Liu, Y.1
Witte, S.2
Liu, Y.-C.3
Doyle, M.4
Elly, C.5
Altman, A.6
-
35
-
-
0035374476
-
Antigen-induced translocation of PKC-θ to membrane rafts is required for T cell activation
-
DOI 10.1038/88765
-
Bi, K. et al. Antigen-induced translocation of PKC-θ to membrane rafts is required for T cell activation. Nat. Immunol. 2, 556-563 (2001). (Pubitemid 33705859)
-
(2001)
Nature Immunology
, vol.2
, Issue.6
, pp. 556-563
-
-
Bi, K.1
Tanaka, Y.2
Coudronniere, N.3
Sugie, K.4
Hong, S.5
Van Stipdonk, M.J.B.6
Altman, A.7
-
36
-
-
0037047136
-
CD28 plays a critical role in the segregation of PKCθ within the immunologic synapse
-
DOI 10.1073/pnas.142298399
-
Huang, J. et al. CD28 plays a critical role in the segregation of PKC θ within the immunologic synapse. Proc. Natl. Acad. Sci. USA 99, 9369-9373 (2002). (Pubitemid 34764620)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.14
, pp. 9369-9373
-
-
Huang, J.1
Lo, P.-F.2
Zal, T.3
Gascoigne, N.R.J.4
Smith, B.A.5
Levin, S.D.6
Grey, H.M.7
-
37
-
-
0347505003
-
CD28-mediated co-stimulation: A quantitative support for TCR signalling
-
Acuto, O. & Michel, F. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat. Rev. Immunol. 3, 939-951 (2003). (Pubitemid 37521536)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.12
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
38
-
-
65349119978
-
CD28 and CTLA-4 coreceptor expression and signal transduction
-
Rudd, C.E., Taylor, A. & Schneider, H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol. Rev. 229, 12-26 (2009).
-
(2009)
Immunol. Rev.
, vol.229
, pp. 12-26
-
-
Rudd, C.E.1
Taylor, A.2
Schneider, H.3
-
39
-
-
71849111698
-
Signals and sequences that control CD28 localization to the central region of the immunological synapse
-
Sanchez-Lockhart, M., Graf, B. & Miller, J. Signals and sequences that control CD28 localization to the central region of the immunological synapse. J. Immunol. 181, 7639-7648 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 7639-7648
-
-
Sanchez-Lockhart, M.1
Graf, B.2
Miller, J.3
-
40
-
-
0034288906
-
A novel functional interaction between Vav and PKCθ is required for TCR-induced T cell activation
-
Villalba, M. et al. A novel functional interaction between Vav and PKCθ is required for TCR-induced T cell activation. Immunity 12, 151-160 (2000). (Pubitemid 30398629)
-
(2000)
Immunity
, vol.12
, Issue.2
, pp. 151-160
-
-
Villalba, M.1
Coudronniere, N.2
Deckert, M.3
Teixeiro, E.4
Mas, P.5
Altman, A.6
-
41
-
-
0028179931
-
Involvement of p21ras in T cell CD69 expression
-
D'Ambrosio, D., Cantrell, D.A., Frati, L., Santoni, A. & Testi, R. Involvement of p21ras in T cell CD69 expression. Eur. J. Immunol. 24, 616-620 (1994).
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 616-620
-
-
D'Ambrosio, D.1
Cantrell, D.A.2
Frati, L.3
Santoni, A.4
Testi, R.5
-
42
-
-
33646560593
-
Diacylglycerol and protein kinase D localization during T lymphocyte activation
-
DOI 10.1016/j.immuni.2006.02.013, PII S107476130600210X
-
Spitaler, M., Emslie, E., Wood, C.D. & Cantrell, D. Diacylglycerol and protein kinase D localization during T lymphocyte activation. Immunity 24, 535-546 (2006). (Pubitemid 43728156)
-
(2006)
Immunity
, vol.24
, Issue.5
, pp. 535-546
-
-
Spitaler, M.1
Emslie, E.2
Wood, C.D.3
Cantrell, D.4
-
43
-
-
3142733752
-
Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cδ
-
DOI 10.1074/jbc.M403191200
-
Stahelin, R.V. et al. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cδ. J. Biol. Chem. 279, 29501-29512 (2004). (Pubitemid 38915830)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.28
, pp. 29501-29512
-
-
Stahelin, R.V.1
Digman, M.A.2
Medkova, M.3
Ananthanarayanan, B.4
Rafter, J.D.5
Melowic, H.R.6
Cho, W.7
-
44
-
-
2542444383
-
Diacylglycerol-dependent binding recruits PKCθ and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes
-
DOI 10.1091/mbc.E03-11-0844
-
Carrasco, S. & Merida, I. Diacylglycerol-dependent binding recruits PKCθ and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes. Mol. Biol. Cell 15, 2932-2942 (2004). (Pubitemid 38691880)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.6
, pp. 2932-2942
-
-
Carrasco, S.1
Merida, I.2
-
45
-
-
27844439874
-
Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCθ in T lymphocytes
-
DOI 10.1038/sj.emboj.7600856, PII 7600856
-
Thuille, N. et al. Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCθ in T lymphocytes. EMBO J. 24, 3869-3880 (2005). (Pubitemid 41637994)
-
(2005)
EMBO Journal
, vol.24
, Issue.22
, pp. 3869-3880
-
-
Thuille, N.1
Heit, I.2
Fresser, F.3
Krumbock, N.4
Bauer, B.5
Leuthaeusser, S.6
Dammeier, S.7
Graham, C.8
Copeland, T.D.9
Shaw, S.10
Baier, G.11
-
47
-
-
70350128040
-
Small molecule inhibitors of PKCθ as potential antiinflammatory therapeutics
-
Boschelli, D.H. Small molecule inhibitors of PKCθ as potential antiinflammatory therapeutics. Curr. Top. Med. Chem. 9, 640-654 (2009).
-
(2009)
Curr. Top. Med. Chem.
, vol.9
, pp. 640-654
-
-
Boschelli, D.H.1
-
48
-
-
34250642773
-
Generation of T-cell receptor retrogenic mice
-
Holst, J. et al. Generation of T-cell receptor retrogenic mice. Nat. Protoc. 1, 406-417 (2006).
-
(2006)
Nat. Protoc.
, vol.1
, pp. 406-417
-
-
Holst, J.1
-
49
-
-
55349108147
-
Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation
-
Becart, S. et al. Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. Immunity 29, 704-719 (2008).
-
(2008)
Immunity
, vol.29
, pp. 704-719
-
-
Becart, S.1
-
50
-
-
73349133350
-
SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis
-
Canonigo-Balancio, A.J., Fos, C., Prod'homme, T., Becart, S. & Altman, A. SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis. J. Immunol. 183, 7259-7267 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 7259-7267
-
-
Canonigo-Balancio, A.J.1
Fos, C.2
Prod'Homme, T.3
Becart, S.4
Altman, A.5
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