-
2
-
-
0037335514
-
Human zinc fingers as building blocks in the construction of artificial transcription factors
-
Bae KH, Kwon YD, Shin HC et al (2003) Human zinc fingers as building blocks in the construction of artificial transcription factors. Nat Biotechnol 21(3):275-280
-
(2003)
Nat Biotechnol
, vol.21
, Issue.3
, pp. 275-280
-
-
Bae, K.H.1
Kwon, Y.D.2
Shin, H.C.3
-
3
-
-
0036168937
-
Engineering polydactyl zinc-finger transcription factors
-
Beerli RR, Barbas CF 3rd (2002) Engineering polydactyl zinc-finger transcription factors. Nat Biotechnol 20(2):135-141
-
(2002)
Nat Biotechnol
, vol.20
, Issue.2
, pp. 135-141
-
-
Beerli, R.R.1
Barbas, C.F.2
-
4
-
-
58149374562
-
Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases
-
Beumer KJ, Trautman JK, Bozas A et al (2008) Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases. Proc Natl Acad Sci USA 105(50):19821-19826
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.50
, pp. 19821-19826
-
-
Beumer, K.J.1
Trautman, J.K.2
Bozas, A.3
-
5
-
-
84874601177
-
Highly active zinc-finger nucleases by extended modular assembly
-
Bhakta MS, Henry IM, Ousterout DG et al (2013) Highly active zinc-finger nucleases by extended modular assembly. Genome Res 23(3):530-538
-
(2013)
Genome Res
, vol.23
, Issue.3
, pp. 530-538
-
-
Bhakta, M.S.1
Henry, I.M.2
Ousterout, D.G.3
-
6
-
-
0034749283
-
Stimulation of homologous recombination through targeted cleavage by chimeric nucleases
-
Bibikova M, Carroll D, Segal DJ et al (2001) Stimulation of homologous recombination through targeted cleavage by chimeric nucleases. Mol Cell Biol 21(1):289-297
-
(2001)
Mol Cell Biol
, vol.21
, Issue.1
, pp. 289-297
-
-
Bibikova, M.1
Carroll, D.2
Segal, D.J.3
-
7
-
-
80053343092
-
TAL effectors: Customizable proteins for DNA targeting
-
Bogdanove AJ, Voytas DF (2011) TAL effectors: customizable proteins for DNA targeting. Science 333(6051):1843-1846
-
(2011)
Science
, vol.333
, Issue.6051
, pp. 1843-1846
-
-
Bogdanove, A.J.1
Voytas, D.F.2
-
8
-
-
61649085865
-
Targeted transgene integration in plant cells using designed zinc finger nucleases
-
Cai CQ, Doyon Y, Ainley WM et al (2009) Targeted transgene integration in plant cells using designed zinc finger nucleases. Plant Mol Biol 69(6):699-709
-
(2009)
Plant Mol Biol
, vol.69
, Issue.6
, pp. 699-709
-
-
Cai, C.Q.1
Doyon, Y.2
Ainley, W.M.3
-
9
-
-
80051535219
-
Genome engineering with zinc-finger nucleases
-
Carroll D (2011) Genome engineering with zinc-finger nucleases. Genetics 188(4):773-782
-
(2011)
Genetics
, vol.188
, Issue.4
, pp. 773-782
-
-
Carroll, D.1
-
10
-
-
79960064013
-
Efficient design and assembly of custom TALENand other TAL effector-based constructs for DNA targeting
-
Cermak T, Doyle EL, Christian M et al (2011) Efficient design and assembly of custom TALENand other TAL effector-based constructs for DNA targeting. Nucleic Acids Res 39(12):e82
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.12
-
-
Cermak, T.1
Doyle, E.L.2
Christian, M.3
-
11
-
-
80052292973
-
High-frequency genome editing using ssDNAoligonucleotides with zinc-finger nucleases
-
Chen F, Pruett-Miller SM, Huang Y et al (2011) High-frequency genome editing using ssDNAoligonucleotides with zinc-finger nucleases. Nat Methods 8(9):753-755
-
(2011)
Nat Methods
, vol.8
, Issue.9
, pp. 753-755
-
-
Chen, F.1
Pruett-Miller, S.M.2
Huang, Y.3
-
12
-
-
84886043841
-
Receptor-mediated delivery of engineered nucleasesfor genome modification
-
Chen Z, Jaafar L, Agyekum DG et al (2013) Receptor-mediated delivery of engineered nucleasesfor genome modification. Nucleic Acids Res 41(19):e182
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.19
-
-
Chen, Z.1
Jaafar, L.2
Agyekum, D.G.3
-
13
-
-
78951479577
-
Targeting DNA double-strand breaks with TALeffector nucleases
-
Christian M, Cermak T, Doyle EL et al (2010) Targeting DNA double-strand breaks with TALeffector nucleases. Genetics 186(2):757-761
-
(2010)
Genetics
, vol.186
, Issue.2
, pp. 757-761
-
-
Christian, M.1
Cermak, T.2
Doyle, E.L.3
-
14
-
-
84885780340
-
Targeted mutagenesis of Arabidopsis thaliana using engineered TAL effector nucleases (TALENs)
-
Christian M, Qi Y, Zhang Y, Voytas DF (2013) Targeted mutagenesis of Arabidopsis thaliana using engineered TAL effector nucleases (TALENs). G3 (Bethesda) 3(10):1697-1705
-
(2013)
G3 (Bethesda)
, vol.3
, Issue.10
, pp. 1697-1705
-
-
Christian, M.1
Qi, Y.2
Zhang, Y.3
Voytas, D.F.4
-
15
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L, Ran FA, Cox D et al (2013) Multiplex genome engineering using CRISPR/Cas systems.Science 339(6121):819-823
-
(2013)
Science
, vol.339
, Issue.6121
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
-
16
-
-
38849103093
-
DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases
-
Cornu TI, Thibodeau-Beganny S, Guhl E et al (2008) DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases. Mol Ther 16(2):352-358
-
(2008)
Mol Ther
, vol.16
, Issue.2
, pp. 352-358
-
-
Cornu, T.I.1
Thibodeau-Beganny, S.2
Guhl, E.3
-
17
-
-
79955792807
-
ZFN-site searches genomes forzinc finger nuclease target sites and off-target sites
-
Cradick TJ, Ambrosini G, Iseli C, Bucher P, McCaffrey AP (2011) ZFN-site searches genomes forzinc finger nuclease target sites and off-target sites. BMC Bioinformatics 12:152
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 152
-
-
Cradick, T.J.1
Ambrosini, G.2
Iseli, C.3
Bucher, P.4
Mc Caffrey, A.P.5
-
18
-
-
78651322138
-
Targeted integration in rat andmouse embryos with zinc-finger nucleases
-
Cui X, Ji D, Fisher DA, Wu Y, Briner DM, Weinstein EJ (2011) Targeted integration in rat andmouse embryos with zinc-finger nucleases. Nat Biotechnol 29(1):64-67
-
(2011)
Nat Biotechnol
, vol.29
, Issue.1
, pp. 64-67
-
-
Cui, X.1
Ji, D.2
Fisher, D.A.3
Wu, Y.4
Briner, D.M.5
Weinstein, E.J.6
-
19
-
-
79958065910
-
Targeted mutagenesis of duplicated genes in soybeanwith zinc-finger nucleases
-
Curtin SJ, Zhang F, Sander JD et al (2011) Targeted mutagenesis of duplicated genes in soybeanwith zinc-finger nucleases. Plant Physiol 156(2):466-473
-
(2011)
Plant Physiol
, vol.156
, Issue.2
, pp. 466-473
-
-
Curtin, S.J.1
Zhang, F.2
Sander, J.D.3
-
20
-
-
70349103842
-
ZFN-induced mutagenesis and gene-targeting in Arabidopsis through Agrobacterium-mediated floral dip transformation
-
de Pater S, Neuteboom LW, Pinas JE, Hooykaas PJ, van der Zaal BJ (2009) ZFN-induced mutagenesis and gene-targeting in Arabidopsis through Agrobacterium-mediated floral dip transformation. Plant Biotechnol J 7(8):821-835
-
(2009)
Plant Biotechnol J
, vol.7
, Issue.8
, pp. 821-835
-
-
De Pater, S.1
Neuteboom, L.W.2
Pinas, J.E.3
Hooykaas, P.J.4
Van Der Zaal, B.J.5
-
21
-
-
84876955340
-
ZFN-mediated gene targeting of the Arabidopsis protoporphyrinogen oxidase gene through Agrobacterium-mediated floral diptransformation
-
de Pater S, Pinas JE, Hooykaas PJ, van der Zaal BJ (2012) ZFN-mediated gene targeting of the Arabidopsis protoporphyrinogen oxidase gene through Agrobacterium-mediated floral diptransformation. Plant Biotechnol J 11(4):510-515
-
(2012)
Plant Biotechnol J
, vol.11
, Issue.4
, pp. 510-515
-
-
De Pater, S.1
Pinas, J.E.2
Hooykaas, P.J.3
Van Der Zaal, B.J.4
-
22
-
-
44949155482
-
Heritable targeted gene disruption in zebrafishusing designed zinc-finger nucleases
-
Doyon Y, McCammon JM, Miller JC et al (2008) Heritable targeted gene disruption in zebrafishusing designed zinc-finger nucleases. Nat Biotechnol 26(6):702-708
-
(2008)
Nat Biotechnol
, vol.26
, Issue.6
, pp. 702-708
-
-
Doyon, Y.1
Mc Cammon, J.M.2
Miller, J.C.3
-
23
-
-
78650912707
-
Enhancing zinc-finger-nuclease activity with improvedobligate heterodimeric architectures
-
Doyon Y, Vo TD, Mendel MC et al (2011) Enhancing zinc-finger-nuclease activity with improvedobligate heterodimeric architectures. Nat Methods 8(1):74-79
-
(2011)
Nat Methods
, vol.8
, Issue.1
, pp. 74-79
-
-
Doyon, Y.1
Vo, T.D.2
Mendel, M.C.3
-
24
-
-
82355181082
-
Localizedegg-cell expression of effector proteins for targeted modification of the Arabidopsis genome
-
Even-Faitelson L, Samach A, Melamed-Bessudo C, Avivi-Ragolsky N, Levy AA (2011) Localizedegg-cell expression of effector proteins for targeted modification of the Arabidopsis genome.Plant J 68(5):929-937
-
(2011)
Plant J
, vol.68
, Issue.5
, pp. 929-937
-
-
Even-Faitelson, L.1
Samach, A.2
Melamed-Bessudo, C.3
Avivi-Ragolsky, N.4
Levy, A.A.5
-
25
-
-
84885181396
-
Efficient genome editing in plants using a CRISPR/Cas system
-
Feng Z, Zhang B, Ding W et al (2013) Efficient genome editing in plants using a CRISPR/Cas system. Cell Res 23(10):1229-1232
-
(2013)
Cell Res
, vol.23
, Issue.10
, pp. 1229-1232
-
-
Feng, Z.1
Zhang, B.2
Ding, W.3
-
26
-
-
84876522437
-
Zinc Finger Database (ZiFDB) v2.0: A comprehensive database of C2H2 zinc fingers and engineered zinc finger arrays
-
Fu F, Voytas DF (2013) Zinc Finger Database (ZiFDB) v2.0: a comprehensive database of C2H2 zinc fingers and engineered zinc finger arrays. Nucleic Acids Res 41 (Databaseissue):D452-D455
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Fu, F.1
Voytas, D.F.2
-
27
-
-
58149187901
-
Zinc Finger Database (ZiFDB): A repository for information on C2H2 zinc fingers and engineered zinc-finger arrays
-
Fu F, Sander JD, Maeder M et al (2009) Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays. Nucleic Acids Res 37(Database issue):D279-D283
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Fu, F.1
Sander, J.D.2
Maeder, M.3
-
28
-
-
73949148680
-
Hypersensitivity to DNA damage in plant stem cell niches
-
Fulcher N, Sablowski R (2009) Hypersensitivity to DNA damage in plant stem cell niches. Proc Natl Acad Sci U S A 106(49):20984-20988
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.49
, pp. 20984-20988
-
-
Fulcher, N.1
Sablowski, R.2
-
29
-
-
80052766645
-
An unbiased genome-wide analysis of zinc-finger nuclease specificity
-
Gabriel R, Lombardo A, Arens A et al (2011) An unbiased genome-wide analysis of zinc-finger nuclease specificity. Nat Biotechnol 29(9):816-823
-
(2011)
Nat Biotechnol
, vol.29
, Issue.9
, pp. 816-823
-
-
Gabriel, R.1
Lombardo, A.2
Arens, A.3
-
30
-
-
84864439768
-
Targeted gene knockout by direct delivery ofzinc-finger nuclease proteins
-
Gaj T, Guo J, Kato Y, Sirk SJ, Barbas CF 3rd (2012) Targeted gene knockout by direct delivery ofzinc-finger nuclease proteins. Nat Methods 9(8):805-807
-
(2012)
Nat Methods
, vol.9
, Issue.8
, pp. 805-807
-
-
Gaj, T.1
Guo, J.2
Kato, Y.3
Sirk, S.J.4
Barbas, C.F.5
-
31
-
-
78049479360
-
A ubiquitin-10promoter-based vector set for fluorescent protein tagging facilitates temporal stability andnative protein distribution in transient and stable expression studies
-
Grefen C, Donald N, Hashimoto K, Kudla J, Schumacher K, Blatt MR (2010) A ubiquitin-10promoter-based vector set for fluorescent protein tagging facilitates temporal stability andnative protein distribution in transient and stable expression studies. Plant J 64(2):355-365
-
(2010)
Plant J
, vol.64
, Issue.2
, pp. 355-365
-
-
Grefen, C.1
Donald, N.2
Hashimoto, K.3
Kudla, J.4
Schumacher, K.5
Blatt, M.R.6
-
32
-
-
84861982214
-
An optimized two-finger archive for ZFN-mediated gene targeting
-
Gupta A, Christensen RG, Rayla AL, Lakshmanan A, Stormo GD, Wolfe SA (2012) An optimized two-finger archive for ZFN-mediated gene targeting. Nat Methods 9(6):588-590
-
(2012)
Nat Methods
, vol.9
, Issue.6
, pp. 588-590
-
-
Gupta, A.1
Christensen, R.G.2
Rayla, A.L.3
Lakshmanan, A.4
Stormo, G.D.5
Wolfe, S.A.6
-
33
-
-
84886926151
-
Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice
-
Jiang W, Zhou H, Bi H, Fromm M, Yang B, Weeks DP (2013) Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice.Nucleic Acids Res 41(20):e188
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.20
-
-
Jiang, W.1
Zhou, H.2
Bi, H.3
Fromm, M.4
Yang, B.5
Weeks, D.P.6
-
34
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337(6096):816-821
-
(2012)
Science
, vol.337
, Issue.6096
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
35
-
-
84878490390
-
A rapid assay to quantify the cleavage efficiency of custom-designed nucleases in planta
-
Johnson RA, Gurevich V, Levy AA (2013) A rapid assay to quantify the cleavage efficiency of custom-designed nucleases in planta. Plant Mol Biol 82(3):207-221
-
(2013)
Plant Mol Biol
, vol.82
, Issue.3
, pp. 207-221
-
-
Johnson, R.A.1
Gurevich, V.2
Levy, A.A.3
-
36
-
-
0030032063
-
Hybrid restriction enzymes: Zinc finger fusions to Fok Icleavage domain
-
Kim YG, Cha J, Chandrasegaran S (1996) Hybrid restriction enzymes: zinc finger fusions to Fok Icleavage domain. Proc Natl Acad Sci U S A 93(3):1156-1160
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.3
, pp. 1156-1160
-
-
Kim, Y.G.1
Cha, J.2
Chandrasegaran, S.3
-
37
-
-
78650855391
-
Preassembled zinc-finger arrays for rapid construction of ZFNs
-
Kim S, Lee MJ, Kim H, Kang M, Kim JS (2011) Preassembled zinc-finger arrays for rapid construction of ZFNs. Nat Methods 8(1):7
-
(2011)
Nat Methods
, vol.8
, Issue.1
, pp. 7
-
-
Kim, S.1
Lee, M.J.2
Kim, H.3
Kang, M.4
Kim, J.S.5
-
38
-
-
74949133880
-
Targeted chromosomal deletions in human cells using zinc finger nucleases
-
Lee HJ, Kim E, Kim JS (2010) Targeted chromosomal deletions in human cells using zinc finger nucleases. Genome Res 20(1):81-89
-
(2010)
Genome Res
, vol.20
, Issue.1
, pp. 81-89
-
-
Lee, H.J.1
Kim, E.2
Kim, J.S.3
-
39
-
-
84863275797
-
Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases
-
Lee HJ, Kweon J, Kim E, Kim S, Kim JS (2011) Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases. Genome Res 22(3):539-548
-
(2011)
Genome Res
, vol.22
, Issue.3
, pp. 539-548
-
-
Lee, H.J.1
Kweon, J.2
Kim, E.3
Kim, S.4
Kim, J.S.5
-
40
-
-
78651270582
-
TAL nucleases (TALNs): Hybrid proteins composed of TALeffectors and FokI DNA-cleavage domain
-
Li T, Huang S, Jiang WZ et al (2010) TAL nucleases (TALNs): hybrid proteins composed of TALeffectors and FokI DNA-cleavage domain. Nucleic Acids Res 39(1):359-372
-
(2010)
Nucleic Acids Res
, vol.39
, Issue.1
, pp. 359-372
-
-
Li, T.1
Huang, S.2
Jiang, W.Z.3
-
41
-
-
84860736700
-
High-efficiency TALEN-based gene editingproduces disease-resistant rice
-
Li T, Liu B, Spalding MH, Weeks DP, Yang B (2012) High-efficiency TALEN-based gene editingproduces disease-resistant rice. Nat Biotechnol 30(5):390-392
-
(2012)
Nat Biotechnol
, vol.30
, Issue.5
, pp. 390-392
-
-
Li, T.1
Liu, B.2
Spalding, M.H.3
Weeks, D.P.4
Yang, B.5
-
42
-
-
84883785822
-
Multiplex and homologous recombination-mediated genomeediting in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9
-
Li JF, Norville JE, Aach J et al (2013) Multiplex and homologous recombination-mediated genomeediting in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nat Biotechnol31(8):688-691
-
(2013)
Nat Biotechnol
, vol.31
, Issue.8
, pp. 688-691
-
-
Li, J.F.1
Norville, J.E.2
Aach, J.3
-
43
-
-
0037040240
-
Validated zinc finger protein designs for all 16 GNN DNA triplet targets
-
Liu Q, Xia Z, Zhong X, Case CC (2002) Validated zinc finger protein designs for all 16 GNN DNA triplet targets. J Biol Chem 277(6):3850-3856
-
(2002)
J Biol Chem
, vol.277
, Issue.6
, pp. 3850-3856
-
-
Liu, Q.1
Xia, Z.2
Zhong, X.3
Case, C.C.4
-
44
-
-
13844319542
-
Targeted mutagenesis using zinc-finger nucleases in Arabidopsis
-
Lloyd A, Plaisier CL, Carroll D, Drews GN (2005) Targeted mutagenesis using zinc-finger nucleases in Arabidopsis. Proc Natl Acad Sci U S A 102(6):2232-2237
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.6
, pp. 2232-2237
-
-
Lloyd, A.1
Plaisier, C.L.2
Carroll, D.3
Drews, G.N.4
-
45
-
-
47349097567
-
Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification
-
Maeder ML, Thibodeau-Beganny S, Osiak A et al (2008) Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell 31(2):294-301
-
(2008)
Mol Cell
, vol.31
, Issue.2
, pp. 294-301
-
-
Maeder, M.L.1
Thibodeau-Beganny, S.2
Osiak, A.3
-
46
-
-
79952302385
-
De novo-engineeredtranscription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
-
Mahfouz MM, Li L, Shamimuzzaman M, Wibowo A, Fang X, Zhu JK (2011) De novo-engineeredtranscription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proc Natl Acad Sci U S A 108(6):2623-2628
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.6
, pp. 2623-2628
-
-
Mahfouz, M.M.1
Li, L.2
Shamimuzzaman, M.3
Wibowo, A.4
Fang, X.5
Zhu, J.K.6
-
47
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P, Yang L, Esvelt KM et al (2013) RNA-guided human genome engineering via Cas9. Science339(6121):823-826
-
(2013)
Science
, vol.339
, Issue.6121
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
-
48
-
-
33747816812
-
Zinc Finger Tools: Custom DNA-binding domains for transcription factors and nucleases
-
Mandell JG, Barbas CF III (2006) Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases. Nucleic Acids Res 34(Web Server issue):W516-523
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Mandell, J.G.1
Barbas, C.F.2
-
49
-
-
84891932593
-
Application of the CRISPR-Cas Systemfor Efficient Genome Engineering in Plants
-
Mao Y, Zhang H, Xu N, Zhang B, Gao F, Zhu JK (2013) Application of the CRISPR-Cas Systemfor Efficient Genome Engineering in Plants. Mol Plant 6(6):2008-2011
-
(2013)
Mol Plant
, vol.6
, Issue.6
, pp. 2008-2011
-
-
Mao, Y.1
Zhang, H.2
Xu, N.3
Zhang, B.4
Gao, F.5
Zhu, J.K.6
-
50
-
-
78249245697
-
Nontransgenic genome modification in plant cells
-
Marton I, Zuker A, Shklarman E et al (2010) Nontransgenic genome modification in plant cells.Plant Physiol 154(3):1079-1087
-
(2010)
Plant Physiol
, vol.154
, Issue.3
, pp. 1079-1087
-
-
Marton, I.1
Zuker, A.2
Shklarman, E.3
-
51
-
-
84885180177
-
Targeted mutagenesis in rice using CRISPR-Cas system
-
Miao J, Guo D, Zhang J et al (2013) Targeted mutagenesis in rice using CRISPR-Cas system. Cell Res 23(10):1233-1236
-
(2013)
Cell Res
, vol.23
, Issue.10
, pp. 1233-1236
-
-
Miao, J.1
Guo, D.2
Zhang, J.3
-
52
-
-
34447319080
-
An improved zinc-finger nuclease architecture for highly specific genome editing
-
Miller JC, Holmes MC, Wang J et al (2007) An improved zinc-finger nuclease architecture for highly specific genome editing. Nat Biotechnol 25(7):778-785
-
(2007)
Nat Biotechnol
, vol.25
, Issue.7
, pp. 778-785
-
-
Miller, J.C.1
Holmes, M.C.2
Wang, J.3
-
53
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller JC, Tan S, Qiao G et al (2010) A TALE nuclease architecture for efficient genome editing.Nat Biotechnol 29(2):143-148
-
(2010)
Nat Biotechnol
, vol.29
, Issue.2
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
-
54
-
-
84883828590
-
Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
-
Nekrasov V, Staskawicz B, Weigel D, Jones JD, Kamoun S (2013) Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nat Biotechnol31(8):691-693
-
(2013)
Nat Biotechnol
, vol.31
, Issue.8
, pp. 691-693
-
-
Nekrasov, V.1
Staskawicz, B.2
Weigel, D.3
Jones, J.D.4
Kamoun, S.5
-
55
-
-
77955406102
-
Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases
-
Osakabe K, Osakabe Y, Toki S (2010) Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases. Proc Natl Acad Sci U S A 107(26):12034-12039
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.26
, pp. 12034-12039
-
-
Osakabe, K.1
Osakabe, Y.2
Toki, S.3
-
56
-
-
33847246298
-
Meganucleases and DNA double-strand break-induced recombination: Perspectives for gene therapy
-
Paques F, Duchateau P (2007) Meganucleases and DNA double-strand break-induced recombination: perspectives for gene therapy. Curr Gene Ther 7(1):49-66
-
(2007)
Curr Gene Ther
, vol.7
, Issue.1
, pp. 49-66
-
-
Paques, F.1
Duchateau, P.2
-
57
-
-
80052293623
-
Revealing off-target cleavage specificities ofzinc-finger nucleases by in vitro selection
-
Pattanayak V, Ramirez CL, Joung JK, Liu DR (2011) Revealing off-target cleavage specificities ofzinc-finger nucleases by in vitro selection. Nat Methods 8(9):765-770
-
(2011)
Nat Methods
, vol.8
, Issue.9
, pp. 765-770
-
-
Pattanayak, V.1
Ramirez, C.L.2
Joung, J.K.3
Liu, D.R.4
-
58
-
-
77954426532
-
Zinc finger nuclease-mediated transgene deletion
-
Petolino JF, Worden A, Curlee K et al (2010) Zinc finger nuclease-mediated transgene deletion.Plant Mol Biol 73(6):617-628
-
(2010)
Plant Mol Biol
, vol.73
, Issue.6
, pp. 617-628
-
-
Petolino, J.F.1
Worden, A.2
Curlee, K.3
-
59
-
-
11444267813
-
The repair of double-strand breaks in plants: Mechanisms and consequences for genome evolution
-
Puchta H (2005) The repair of double-strand breaks in plants: mechanisms and consequences for genome evolution. J Exp Bot 56(409):1-14
-
(2005)
J Exp Bot
, vol.56
, Issue.409
, pp. 1-14
-
-
Puchta, H.1
-
60
-
-
0027384567
-
Homologous recombination in plant cells is enhanced by in vivo induction of double strand breaks into DNA by a site-specific endonuclease
-
Puchta H, Dujon B, Hohn B (1993) Homologous recombination in plant cells is enhanced by in vivo induction of double strand breaks into DNA by a site-specific endonuclease. NucleicAcids Res 21(22):5034-5040
-
(1993)
NucleicAcids Res
, vol.21
, Issue.22
, pp. 5034-5040
-
-
Puchta, H.1
Dujon, B.2
Hohn, B.3
-
61
-
-
84934437041
-
Tailor-made mutations in Arabidopsis using zinc finger nucleases
-
Qi Y, Starker CG, Zhang F, Baltes NJ, Voytas DF (2013a) Tailor-made mutations in Arabidopsis using zinc finger nucleases. Methods Mol Biol 1062:193-209
-
(2013)
Methods Mol Biol
, vol.1062
, pp. 193-209
-
-
Qi, Y.1
Starker, C.G.2
Zhang, F.3
Baltes, N.J.4
Voytas, D.F.5
-
62
-
-
84874643080
-
Increasing frequencies of site-specific mutagenesis and genetargeting in Arabidopsis by manipulating DNA repair pathways
-
Qi Y, Zhang Y, Zhang F et al (2013b) Increasing frequencies of site-specific mutagenesis and genetargeting in Arabidopsis by manipulating DNA repair pathways. Genome Res 23(3):547-554
-
(2013)
Genome Res
, vol.23
, Issue.3
, pp. 547-554
-
-
Qi, Y.1
Zhang, Y.2
Zhang, F.3
-
63
-
-
84944538066
-
Targeted deletion and inversion of tandemly arrayed genes inArabidopsis thaliana using zinc finger nucleases
-
Qi Y, Li X, Zhang Y et al (2013c) Targeted deletion and inversion of tandemly arrayed genes inArabidopsis thaliana using zinc finger nucleases. G3 (Bethesda) 3(10):1701-1715
-
(2013)
G3 (Bethesda)
, vol.3
, Issue.10
, pp. 1701-1715
-
-
Qi, Y.1
Li, X.2
Zhang, Y.3
-
64
-
-
42949083192
-
Unexpected failure rates for modular assembly ofengineered zinc fingers
-
Ramirez CL, Foley JE, Wright DA et al (2008) Unexpected failure rates for modular assembly ofengineered zinc fingers. Nat Methods 5(5):374-375
-
(2008)
Nat Methods
, vol.5
, Issue.5
, pp. 374-375
-
-
Ramirez, C.L.1
Foley, J.E.2
Wright, D.A.3
-
65
-
-
84861960685
-
Engineered zinc finger nickases inducehomology-directed repair with reduced mutagenic effects
-
Ramirez CL, Certo MT, Mussolino C et al (2012) Engineered zinc finger nickases inducehomology-directed repair with reduced mutagenic effects. Nucleic Acids Res 40(12):5560-5568
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.12
, pp. 5560-5568
-
-
Ramirez, C.L.1
Certo, M.T.2
Mussolino, C.3
-
66
-
-
79251580251
-
ZFNGenome: A comprehensive resource for locating zinc finger nuclease target sites in model organisms
-
Reyon D, Kirkpatrick JR, Sander JD et al (2011) ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms. BMC Genomics 12:83
-
(2011)
BMC Genomics
, vol.12
, pp. 83
-
-
Reyon, D.1
Kirkpatrick, J.R.2
Sander, J.D.3
-
67
-
-
78650863981
-
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)
-
Sander JD, Dahlborg EJ, Goodwin MJ et al (2010a) Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nat Methods 8(1):67-69
-
(2010)
Nat Methods
, vol.8
, Issue.1
, pp. 67-69
-
-
Sander, J.D.1
Dahlborg, E.J.2
Goodwin, M.J.3
-
68
-
-
77954295352
-
ZiFiT (Zinc FingerTargeter): An updated zinc finger engineering tool
-
Sander JD, Maeder ML, Reyon D, Voytas DF, Joung JK, Dobbs D (2010) ZiFiT (Zinc FingerTargeter): an updated zinc finger engineering tool. Nucleic Acids Res 38(Web Serverissue):W462-468
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Sander, J.D.1
Maeder, M.L.2
Reyon, D.3
Voytas, D.F.4
Joung, J.K.5
Dobbs, D.6
-
69
-
-
84885979507
-
In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites
-
Sander JD, Ramirez CL, Linder SJ et al (2013) In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites. Nucleic Acids Res 41(19):e181
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.19
-
-
Sander, J.D.1
Ramirez, C.L.2
Linder, S.J.3
-
70
-
-
0344839044
-
Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins
-
Segal DJ, Beerli RR, Blancafort P et al (2003) Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins. Biochemistry 42(7):2137-2148
-
(2003)
Biochemistry
, vol.42
, Issue.7
, pp. 2137-2148
-
-
Segal, D.J.1
Beerli, R.R.2
Blancafort, P.3
-
71
-
-
24744454355
-
High-frequency gene targeting in Arabidopsisplants expressing the yeast RAD54 gene
-
Shaked H, Melamed-Bessudo C, Levy AA (2005) High-frequency gene targeting in Arabidopsisplants expressing the yeast RAD54 gene. Proc Natl Acad Sci U S A 102(34):12265-12269
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.34
, pp. 12265-12269
-
-
Shaked, H.1
Melamed-Bessudo, C.2
Levy, A.A.3
-
72
-
-
84880737219
-
Rapid and efficient gene modification in rice and brachypo-dium using TALENs
-
Shan Q, Wang Y, Chen K et al (2013) Rapid and efficient gene modification in rice and brachypo-dium using TALENs. Mol Plant 6(4):1365-1368
-
(2013)
Mol Plant
, vol.6
, Issue.4
, pp. 1365-1368
-
-
Shan, Q.1
Wang, Y.2
Chen, K.3
-
73
-
-
85042815594
-
Targeted genome modification of crop plants using a CRISPR-Cas system
-
Shan Q, Wang Y, Li J et al (2013) Targeted genome modification of crop plants using a CRISPR-Cas system. Nat Biotechnol 31(8):686-688
-
(2013)
Nat Biotechnol
, vol.31
, Issue.8
, pp. 686-688
-
-
Shan, Q.1
Wang, Y.2
Li, J.3
-
74
-
-
66249147273
-
Precise genome modification in the crop species Zea mays using zinc-finger nucleases
-
Shukla VK, Doyon Y, Miller JC et al (2009) Precise genome modification in the crop species Zea mays using zinc-finger nucleases. Nature 459(7245):437-441
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 437-441
-
-
Shukla, V.K.1
Doyon, Y.2
Miller, J.C.3
-
75
-
-
33845914020
-
A combinatorial approach to create artificial homingendonucleases cleaving chosen sequences
-
Smith J, Grizot S, Arnould S et al (2006) A combinatorial approach to create artificial homingendonucleases cleaving chosen sequences. Nucleic Acids Res 34(22):e149
-
(2006)
Nucleic Acids Res
, vol.34
, Issue.22
-
-
Smith, J.1
Grizot, S.2
Arnould, S.3
-
76
-
-
77957755672
-
Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion
-
Sollu C, Pars K, Cornu TI et al (2010) Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion. Nucleic Acids Res 38(22):8269-8276
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.22
, pp. 8269-8276
-
-
Sollu, C.1
Pars, K.2
Cornu, T.I.3
-
77
-
-
34447323568
-
Structure-basedredesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
-
Szczepek M, Brondani V, Buchel J, Serrano L, Segal DJ, Cathomen T (2007) Structure-basedredesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. NatBiotechnol 25(7):786-793
-
(2007)
NatBiotechnol
, vol.25
, Issue.7
, pp. 786-793
-
-
Szczepek, M.1
Brondani, V.2
Buchel, J.3
Serrano, L.4
Segal, D.J.5
Cathomen, T.6
-
78
-
-
2342471959
-
Correction of multi-gene deficiency in vivo using a single “self-cleaving” 2A peptide-based retroviral vector
-
Szymczak AL, Workman CJ, Wang Y et al (2004) Correction of multi-gene deficiency in vivo using a single “self-cleaving” 2A peptide-based retroviral vector. Nat Biotechnol 22(5):589-594
-
(2004)
Nat Biotechnol
, vol.22
, Issue.5
, pp. 589-594
-
-
Szymczak, A.L.1
Workman, C.J.2
Wang, Y.3
-
79
-
-
59149103100
-
A toolbox and procedural notes for characterizing novel zincfinger nucleases for genome editing in plant cells
-
Tovkach A, Zeevi V, Tzfira T (2009) A toolbox and procedural notes for characterizing novel zincfinger nucleases for genome editing in plant cells. Plant J 57(4):747-757
-
(2009)
Plant J
, vol.57
, Issue.4
, pp. 747-757
-
-
Tovkach, A.1
Zeevi, V.2
Tzfira, T.3
-
80
-
-
66249093890
-
High-frequency modification of plant genesusing engineered zinc-finger nucleases
-
Townsend JA, Wright DA, Winfrey RJ et al (2009) High-frequency modification of plant genesusing engineered zinc-finger nucleases. Nature 459(7245):442-445
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 442-445
-
-
Townsend, J.A.1
Wright, D.A.2
Winfrey, R.J.3
-
81
-
-
84859420035
-
Genome modifications in plant cells by custom-made restriction enzymes
-
Tzfira T, Weinthal D, Marton I, Zeevi V, Zuker A, Vainstein A (2012) Genome modifications in plant cells by custom-made restriction enzymes. Plant Biotechnol J 10(4):373-389
-
(2012)
Plant Biotechnol J
, vol.10
, Issue.4
, pp. 373-389
-
-
Tzfira, T.1
Weinthal, D.2
Marton, I.3
Zeevi, V.4
Zuker, A.5
Vainstein, A.6
-
82
-
-
84874627868
-
Plant genome engineering with sequence-specific nucleases
-
Voytas DF (2013) Plant genome engineering with sequence-specific nucleases. Annu Rev PlantBiol 64:327-350
-
(2013)
Annu Rev PlantBiol
, vol.64
, pp. 327-350
-
-
Voytas, D.F.1
-
83
-
-
84866139334
-
Non-transgenic genome modifications in a hemime-tabolous insect using zinc-finger and TAL effector nucleases
-
Watanabe T, Ochiai H, Sakuma T et al (2012) Non-transgenic genome modifications in a hemime-tabolous insect using zinc-finger and TAL effector nucleases. Nat Commun 3:1017
-
(2012)
Nat Commun
, vol.3
, pp. 1017
-
-
Watanabe, T.1
Ochiai, H.2
Sakuma, T.3
-
84
-
-
77953285393
-
Genome editing in plant cells by zinc fingernucleases
-
Weinthal D, Tovkach A, Zeevi V, Tzfira T (2010) Genome editing in plant cells by zinc fingernucleases. Trends Plant Sci 15(6):308-321
-
(2010)
Trends Plant Sci
, vol.15
, Issue.6
, pp. 308-321
-
-
Weinthal, D.1
Tovkach, A.2
Zeevi, V.3
Tzfira, T.4
-
85
-
-
84877033242
-
Nonhomologous end joining-mediated gene replacement in plant cells
-
Weinthal DM, Taylor RA, Tzfira T (2013) Nonhomologous end joining-mediated gene replacement in plant cells. Plant Physiol 162(1):390-400
-
(2013)
Plant Physiol
, vol.162
, Issue.1
, pp. 390-400
-
-
Weinthal, D.M.1
Taylor, R.A.2
Tzfira, T.3
-
86
-
-
84884350172
-
TAL effector nucleases induce mutations at a preselected location in the genome of primary barley transformants
-
Wendt T, Holm PB, Starker CG et al (2013) TAL effector nucleases induce mutations at a preselected location in the genome of primary barley transformants. Plant Mol Biol 83(3):279-285
-
(2013)
Plant Mol Biol
, vol.83
, Issue.3
, pp. 279-285
-
-
Wendt, T.1
Holm, P.B.2
Starker, C.G.3
-
87
-
-
33644693285
-
High-frequency homologous recombinationin plants mediated by zinc-finger nucleases
-
Wright DA, Townsend JA, Winfrey RJ Jr et al (2005) High-frequency homologous recombinationin plants mediated by zinc-finger nucleases. Plant J 44(4):693-705
-
(2005)
Plant J
, vol.44
, Issue.4
, pp. 693-705
-
-
Wright, D.A.1
Townsend, J.A.2
Winfrey, R.J.3
-
88
-
-
34248220864
-
Standardized reagents and protocols forengineering zinc finger nucleases by modular assembly
-
Wright DA, Thibodeau-Beganny S, Sander JD et al (2006) Standardized reagents and protocols forengineering zinc finger nucleases by modular assembly. Nat Protoc 1(3):1637-1652
-
(2006)
Nat Protoc
, vol.1
, Issue.3
, pp. 1637-1652
-
-
Wright, D.A.1
Thibodeau-Beganny, S.2
Sander, J.D.3
-
89
-
-
84884962826
-
RNA-guided Genome Editing in Plants Using A CRISPR-Cas System
-
Xie K, Yang Y (2013) RNA-guided Genome Editing in Plants Using A CRISPR-Cas System. MolPlant 6(6):1975-1983
-
(2013)
MolPlant
, vol.6
, Issue.6
, pp. 1975-1983
-
-
Xie, K.1
Yang, Y.2
-
90
-
-
33644840365
-
An egg apparatus-specific enhancer of Arabidopsis, identified by enhancer detection
-
Yang W, Jefferson RA, Huttner E, Moore JM, Gagliano WB, Grossniklaus U (2005) An egg apparatus-specific enhancer of Arabidopsis, identified by enhancer detection. Plant Physiol139(3):1421-1432
-
(2005)
Plant Physiol
, vol.139
, Issue.3
, pp. 1421-1432
-
-
Yang, W.1
Jefferson, R.A.2
Huttner, E.3
Moore, J.M.4
Gagliano, W.B.5
Grossniklaus, U.6
-
91
-
-
79953783824
-
Targeted mutagenesis in Arabidopsis using zinc-finger nucleases
-
Zhang F, Voytas DF (2011) Targeted mutagenesis in Arabidopsis using zinc-finger nucleases. Methods Mol Biol 701:167-177
-
(2011)
Methods Mol Biol
, vol.701
, pp. 167-177
-
-
Zhang, F.1
Voytas, D.F.2
-
92
-
-
77955395799
-
High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases
-
Zhang F, Maeder ML, Unger-Wallace E et al (2010) High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proc Natl Acad Sci US A 107(26):12028-12033
-
(2010)
Proc Natl Acad Sci US A
, vol.107
, Issue.26
, pp. 12028-12033
-
-
Zhang, F.1
Maeder, M.L.2
Unger-Wallace, E.3
-
93
-
-
84871803423
-
Transcription activator-like effector nucleases enable efficient plant genome engineering
-
Zhang Y, Zhang F, Li X et al (2013) Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiol 161(1):20-27
-
(2013)
Plant Physiol
, vol.161
, Issue.1
, pp. 20-27
-
-
Zhang, Y.1
Zhang, F.2
Li, X.3
|