Dna repair by mgmt, but not aag, causes a threshold in alkylation-induced colorectal carcinogenesis

Carcinogenesis

Volumn 36, Issue 10, 2015, Pages 1235-1244

  Fahrer, Jörg ^a   Frisch, Janina ^a   Nagel, Georg ^a   Kraus, Alexander ^a   Dörsam, Bastian ^a   Thomas, Adam D ^a   Reißig, Sonja ^a   Waisman, Ari ^a   Kaina, Bernd ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; AZOXYMETHANE; CHECKPOINT KINASE 1; DEXTRAN SULFATE; DNA GLYCOSYLTRANSFERASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; N ALKYLADENINE DNA GLYCOSYLASE; NITROSO DERIVATIVE; PROTEIN P53; UNCLASSIFIED DRUG; 3-METHYLADENINE-DNA GLYCOSYLASE; DNA LIGASE; DNA METHYLTRANSFERASE; MGMT PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; COLONOSCOPY; COLORECTAL CANCER; COLORECTAL CARCINOGENESIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA ADDUCT; DNA ALKYLATION; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENOTOXICITY; GENOTYPE; IMMUNOHISTOCHEMISTRY; LIMIT OF QUANTITATION; METABOLIC ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR VOLUME; ANIMAL; CHEMICALLY INDUCED; COLORECTAL TUMOR; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; CARCINOGENESIS; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; DNA GLYCOSYLASES; DNA MODIFICATION METHYLASES; DNA REPAIR; DNA REPAIR ENZYMES; HUMANS; MICE; MICE, TRANSGENIC; NITROSO COMPOUNDS; TUMOR SUPPRESSOR PROTEINS;

EID: 84943787824     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgv114     Document Type: Article

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