In vivo studies in the mouse to define a threshold for the genotoxicity of EMS and ENU

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 678, Issue 2, 2009, Pages 101-107

  Gocke, Elmar ^a   Müller, Lutz ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Dose response; EMS; ENU; In vivo genotoxicity; Risk assessment; Threshold

Indexed keywords

BETA GALACTOSIDASE; ETHYLNITROSOUREA; MESYLIC ACID ETHYL ESTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; CONTROLLED STUDY; DOSE RESPONSE; GASTROINTESTINAL TRACT; GENE; GENE MUTATION; GENOTOXICITY; IN VIVO STUDY; LIVER; MICRONUCLEUS; MICRONUCLEUS TEST; MOUSE; MUTAGENIC ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RISK;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ETHYL METHANESULFONATE; MICE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; RISK ASSESSMENT; THRESHOLD LIMIT VALUES;

EID: 69449108362     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2009.04.005     Document Type: Article

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