Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose-response relationships, exemplified for mutagenicity data

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 678, Issue 2, 2009, Pages 118-122

  Lutz, Werner K ^a   Lutz, Roman W ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b ETH ZURICH   (Switzerland)

Author keywords

Dose response relationships; Genotoxicity; Mutagenicity; Risk assessment; Statistical models

Indexed keywords

BETA GALACTOSIDASE; MESYLIC ACID ETHYL ESTER; MESYLIC ACID METHYL ESTER; THYMIDINE KINASE;

ANALYSIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BIOLOGY; BONE MARROW CELL; CALCULATION; COMPUTER PROGRAM; CONTROL GROUP; CONTROLLED STUDY; DOSE RESPONSE; LINEAR REGRESSION ANALYSIS; LYMPHOMA CELL; MATHEMATICAL MODEL; MOUSE; MUTAGENICITY; MUTANT; NONHUMAN; PARAMETER; PRIORITY JOURNAL; STATISTICAL MODEL; TRANSGENIC MOUSE;

ANIMALS; CONFIDENCE INTERVALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MODELS, STATISTICAL; MUTAGENICITY TESTS; MUTAGENS; SOFTWARE; THRESHOLD LIMIT VALUES;

MUS MUSCULUS;

EID: 69449107550     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2009.05.010     Document Type: Article

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