Does increase in DNA repair allow "Tolerance-to-Insult" in chemical carcinogenesis? Skin tumor experiments with MGMT-overexpressing mice

Environmental and Molecular Mutagenesis

Volumn 55, Issue 2, 2014, Pages 145-150

  Becker, Klaus ^a   Thomas, Adam D ^b   Kaina, Bernd ^b  

^a LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Alkyltransferase; Dose response; Methylnitrosourea; MGMT; Threshold in carcinogenesis

Indexed keywords

ALKYLTRANSFERASE; DOSE-RESPONSE; METHYLNITROSOUREA; MGMT; THRESHOLD IN CARCINOGENESIS;

ANIMALS; CARCINOGENESIS; DISEASE RESISTANCE; DNA MODIFICATION METHYLASES; DNA REPAIR; DNA REPAIR ENZYMES; GENE EXPRESSION; HUMANS; METHYLNITROSOUREA; MICE; MICE, TRANSGENIC; PAPILLOMA; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE; TUMOR SUPPRESSOR PROTEINS;

EID: 84893779393     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21834     Document Type: Article

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