Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

Environmental and Molecular Mutagenesis

Volumn 54, Issue 1, 2013, Pages 8-18

  Gollapudi, B B ^a   Johnson, G E ^b   Hernandez, L G ^c   Pottenger, L H ^a   Dearfield, K L ^d   Jeffrey, A M ^e   Julien, E ^f   Kim, J H ^g   Lovell, D P ^h   Macgregor, J T ⁱ   Moore, M M ^j   van Benthem, J ^c   White, P A ^k   Zeiger, E ^l   Thybaud, V ^m  

^a DOW CHEMICAL COMPANY   (United States)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^d U S DEPARTMENT OF AGRICULTURE   (United States)

^e NEW YORK MEDICAL COLLEGE   (United States)

^f LifeSci Research Service   (United States)

^g ILSI HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE   (United States)

^h ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

ⁱ Toxicology Consulting Services   (United States)

^j NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^k Environmental Health Center   (Canada)

^l Errol Zeiger Consulting   (United States)

^m SANOFI   (France)

more..

Author keywords

Benchmark dose; Dose response; Low dose; Mutagenicity; No observed genotoxic effect level; Point of departure; Risk assessment

Indexed keywords

MESYLIC ACID METHYL ESTER;

ARTICLE; DOSE RESPONSE; GENE MUTATION; GENETIC TOXICOLOGY; GENOTOXICITY; HUMAN; MAXIMUM ALLOWABLE CONCENTRATION; METRIC SYSTEM; MICRONUCLEUS; QUANTITATIVE ANALYSIS; RISK ASSESSMENT;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, GENETIC; MUTAGENICITY TESTS; MUTATION; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RISK ASSESSMENT;

EID: 84871892918     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21727     Document Type: Article

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