Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine

Nucleic Acids Research

Volumn 42, Issue 13, 2014, Pages 8755-8766

  Koag, Myong Chul ^a   Kou, Yi ^a   Ouzon Shubeita, Hala ^a   Lee, Seongmin ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYLGUANINE; CHEMICAL COMPOUND; DEOXYCYTIDINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE BETA; MAGNESIUM ION; N7 METHYL 2' DEOXYGUANOSINE; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; CATALYSIS; CONTROLLED STUDY; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN QUATERNARY STRUCTURE; STRUCTURE ANALYSIS; X RAY;

DEOXYCYTOSINE NUCLEOTIDES; DEOXYGUANOSINE; DNA; DNA POLYMERASE BETA; GUANINE; HUMANS; KINETICS; MANGANESE; MODELS, MOLECULAR; THYMINE NUCLEOTIDES;

EID: 84905591893     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku554     Document Type: Article

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