SCOPUS 정보 검색 플랫폼

Volumn 16, Issue 15, 2015, Pages 2205-2215

Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates

(14) Katz, Francine S a Pecic, Stevan a Tran, Timothy H b Trakht, Ilya a Schneider, Laura a Zhu, Zhengxiang a Ton That, Long a Luzac, Michal a Zlatanic, Viktor a Damera, Shivani a MacDonald, Joanne a,c Landry, Donald W a Tong, Liang b Stojanovic, Milan N a,b

a Department of Medicine (United States)

b Department of Biological Sciences Columbia University ^* (United States)

c UNIVERSITY OF THE SUNSHINE COAST (Australia)

Author keywords

drug discovery; high throughput screening; medicinal chemistry; neurological agents; structure activity relationships

Indexed keywords

CHOLINESTERASE INHIBITOR; ORGANOPHOSPHATE; ACETYLCHOLINESTERASE; PHENOL DERIVATIVE;

ANIMAL EXPERIMENT; APPARENT ASSOCIATION RATE CONSTANT; ARTICLE; BLOOD BRAIN BARRIER; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HIGH THROUGHPUT SCREENING; HUMAN; HYDROLYSIS; KINETIC PARAMETERS; LEUKOCYTE; NONHUMAN; NUCLEOPHILICITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG DEVELOPMENT; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM; SYNTHESIS;

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME ACTIVATION; MOLECULAR STRUCTURE; ORGANOPHOSPHATES; PHENOLS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84943348722 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201500348 Document Type: Article

Times cited : (53)

References (80)

1
- 1342267739
- J. Chambers, S. F. Oppenheimer, Toxicol. Sci. 2004, 77, 185-187;
- (2004) Toxicol. Sci. , vol.77 , pp. 185-187
- Chambers, J.¹ Oppenheimer, S.F.²

2
- 0000249736
- in 10 th ed. (Eds.: J. G. Hardman, L. E. Limbird, A. G. Gilman) McGraw-Hill, New York, p.
- "Anticholinesterase Agents", P. Taylor, in Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10 th ed., (Eds.: J. G. Hardman, L. E. Limbird, A. G. Gilman,) McGraw-Hill, New York, 2001, p. 175;
- (2001) Goodman and Gilman's the Pharmacological Basis of Therapeutics , pp. 175
- Taylor, P.¹

3
- 0141542697
- L. L. Jennings, M. Malecki, E. A. Komives, P. Taylor, Biochemistry 2003, 42, 11083-11091.
- (2003) Biochemistry , vol.42 , pp. 11083-11091
- Jennings, L.L.¹ Malecki, M.² Komives, E.A.³ Taylor, P.⁴

4
- 84936803485
- M. G. Yuantari, C. A. Van Gestel, N. M. Van Straalen, B. Widianarko, H. R. Sunoko, M. N. Shobib, Environ. Monit. Assess. 2015, 187, 142.
- (2015) Environ. Monit. Assess. , vol.187 , pp. 142
- Yuantari, M.G.¹ Van Gestel, C.A.² Van Straalen, N.M.³ Widianarko, B.⁴ Sunoko, H.R.⁵ Shobib, M.N.⁶

5
- 2442702807
- P. Eyer, Toxicol. Rev. 2003, 22, 165-190.
- (2003) Toxicol. Rev. , vol.22 , pp. 165-190
- Eyer, P.¹

6
- 84943358194
- World Health Organization, 2015.
- World Health Organization, http://www.who.int/ipcs/assessment/public-health/pesticides/en/, 2015.

7
- 0036107171
- M. Eddleston, L. Szinicz, P. Eyer, N. Buckley, QJM 2002, 95, 275-283;
- (2002) QJM , vol.95 , pp. 275-283
- Eddleston, M.¹ Szinicz, L.² Eyer, P.³ Buckley, N.⁴

8
- 34447501758
- J. V. Peter, J. L. Moran, P. L. Graham, Expert Opin. Pharmacother. 2007, 8, 1451-1464.
- (2007) Expert Opin. Pharmacother. , vol.8 , pp. 1451-1464
- Peter, J.V.¹ Moran, J.L.² Graham, P.L.³

9
- 0039228261
- I. B. Wilson, Federation Proceedings 1959, 18, 752-758;
- (1959) Federation Proceedings , vol.18 , pp. 752-758
- Wilson, I.B.¹

10
- 19544368045
- I. B. Wilson, B. Ginsburg, Biochim. Biophys. Acta 1955, 18, 168-170.
- (1955) Biochim. Biophys. Acta , vol.18 , pp. 168-170
- Wilson, I.B.¹ Ginsburg, B.²

11
- 0027368530
- M. Harel, I. Schalk, L. Ehret-Sabatier, F. Bouet, M. Goeldner, C. Hirth, P. H. Axelsen, I. Silman, J. L. Sussman, Proc. Natl. Acad. Sci. USA 1993, 90, 9031-9035.
- (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9031-9035
- Harel, M.¹ Schalk, I.² Ehret-Sabatier, L.³ Bouet, F.⁴ Goeldner, M.⁵ Hirth, C.⁶ Axelsen, P.H.⁷ Silman, I.⁸ Sussman, J.L.⁹

12
- 33746765583
- F. Ekström, Y. P. Pang, M. Boman, E. Artursson, C. Akfur, S. Borjegren, Biochem. Pharmacol. 2006, 72, 597-607.
- (2006) Biochem. Pharmacol. , vol.72 , pp. 597-607
- Ekström, F.¹ Pang, Y.P.² Boman, M.³ Artursson, E.⁴ Akfur, C.⁵ Borjegren, S.⁶

13
- 0032892487
- F. Worek, C. Diepold, P. Eyer, Arch. Toxicol. 1999, 73, 7-14.
- (1999) Arch. Toxicol. , vol.73 , pp. 7-14
- Worek, F.¹ Diepold, C.² Eyer, P.³

14
- 84891625711
- K. J. Okolotowicz, M. Dwyer, E. Smith, J. R. Cashman, J. Biochem. Mol. Toxicol. 2014, 28, 23-31.
- (2014) J. Biochem. Mol. Toxicol. , vol.28 , pp. 23-31
- Okolotowicz, K.J.¹ Dwyer, M.² Smith, E.³ Cashman, J.R.⁴

15
- 77955508878
- T. M. Shih, J. W. Skovira, J. C. O'Donnell, J. H. McDonough, Chem.-Biol. Interact. 2010, 187, 207-214;
- (2010) Chem.-Biol. Interact. , vol.187 , pp. 207-214
- Shih, T.M.¹ Skovira, J.W.² O'Donnell, J.C.³ McDonough, J.H.⁴

16
- 0034879904
- R. Chen, L. Raveh, G. Zomber, I. Rabinovitz, G. Cohen, R. Adani, G. Amitai, J. Appl. Toxicol. 2001, 21, 285-291;
- (2001) J. Appl. Toxicol. , vol.21 , pp. 285-291
- Chen, R.¹ Raveh, L.² Zomber, G.³ Rabinovitz, I.⁴ Cohen, G.⁵ Adani, R.⁶ Amitai, G.⁷

17
- 0037439453
- P. Eyer, F. Worek, D. Kiderlen, G. Sinko, A. Stuglin, V. Simeon-Rudolf, E. Reiner, Anal. Biochem. 2003, 312, 224-227;
- (2003) Anal. Biochem. , vol.312 , pp. 224-227
- Eyer, P.¹ Worek, F.² Kiderlen, D.³ Sinko, G.⁴ Stuglin, A.⁵ Simeon-Rudolf, V.⁶ Reiner, E.⁷

18
- 84893953134
- J. Bures, J. Kvetina, M. Pavlik, M. Kunes, M. Kopacova, S. Rejchrt, D. Jun, M. Hrabinova, K. Kuca, I. Tacheci, Neuro Endocrinol. Lett. 2013, 34, 79-83.
- (2013) Neuro Endocrinol. Lett. , vol.34 , pp. 79-83
- Bures, J.¹ Kvetina, J.² Pavlik, M.³ Kunes, M.⁴ Kopacova, M.⁵ Rejchrt, S.⁶ Jun, D.⁷ Hrabinova, M.⁸ Kuca, K.⁹ Tacheci, I.¹⁰

19
- 0036985964
- J. Kassa, G. Krejcova, J. Vachek, Acta Medica (Hradec Kralove) 2002, 45, 149-153;
- (2002) Acta Medica (Hradec Kralove) , vol.45 , pp. 149-153
- Kassa, J.¹ Krejcova, G.² Vachek, J.³

20
- 84943354552
- 30-36
- F. Worek, H. Thiermann, Defence against the Effects of Chemical Hazards: Toxicology, Diagnosis and Medical Countermeasures 2007, 30-31 -30-36;
- (2007) Defence Against the Effects of Chemical Hazards: Toxicology, Diagnosis and Medical Countermeasures , pp. 30-31
- Worek, F.¹ Thiermann, H.²

21
- 0022646867
- C. S. Hatton, T. E. Peto, C. Bunch, G. Pasvol, S. J. Russell, C. R. Singer, G. Edwards, P. Winstanley, Lancet 1986, 1, 411-414.
- (1986) Lancet , vol.1 , pp. 411-414
- Hatton, C.S.¹ Peto, T.E.² Bunch, C.³ Pasvol, G.⁴ Russell, S.J.⁵ Singer, C.R.⁶ Edwards, G.⁷ Winstanley, P.⁸

22
- 84943357971
- F. Worek, P. Elsinghorst, M. Koller, H. Thiermann, Toxicol. Lett. 2014;
- (2014) Toxicol. Lett.
- Worek, F.¹ Elsinghorst, P.² Koller, M.³ Thiermann, H.⁴

23
- 0017833440
- B. Georgiev, E. Khristoskova, Veterinarno-Meditsinski Nauki 1978, 15, 108-115;
- (1978) Veterinarno-Meditsinski Nauki , vol.15 , pp. 108-115
- Georgiev, B.¹ Khristoskova, E.²

24
- 78349249426
- C. Becker, F. Worek, H. John, Drug Testing Anal. 2010, 2, 460-468;
- (2010) Drug Testing Anal. , vol.2 , pp. 460-468
- Becker, C.¹ Worek, F.² John, H.³

25
- 35349018354
- B. Antonijevic, M. P. Stojiljkovic, Clin. Med. Res. 2007, 5, 71-82;
- (2007) Clin. Med. Res. , vol.5 , pp. 71-82
- Antonijevic, B.¹ Stojiljkovic, M.P.²

26
- 28244473567
- F. Worek, L. Szinicz, P. Eyer, H. Thiermann, Toxicol. Appl. Pharmacol. 2005, 209, 193-202;
- (2005) Toxicol. Appl. Pharmacol. , vol.209 , pp. 193-202
- Worek, F.¹ Szinicz, L.² Eyer, P.³ Thiermann, H.⁴

27
- 84905567407
- G. A. Petroianu, D. E. Lorke, G. Athauda, F. Darvas, H. Kalasz, J. Environ. Immunol. Toxicol. 2013, 1, 35-40.
- (2013) J. Environ. Immunol. Toxicol. , vol.1 , pp. 35-40
- Petroianu, G.A.¹ Lorke, D.E.² Athauda, G.³ Darvas, F.⁴ Kalasz, H.⁵

28
- 0022655075
- K. A. Neftel, W. Woodtly, M. Schmid, P. G. Frick, J. Fehr, Br. Med. J. 1986, 292, 721-723;
- (1986) Br. Med. J. , vol.292 , pp. 721-723
- Neftel, K.A.¹ Woodtly, W.² Schmid, M.³ Frick, P.G.⁴ Fehr, J.⁵

29
- 0021049574
- H. K. Schulthess, A. von Felten, J. Gmur, K. Neftel, Schweiz. Med. Wochenschr. 1983, 113, 1912-1913.
- (1983) Schweiz. Med. Wochenschr. , vol.113 , pp. 1912-1913
- Schulthess, H.K.¹ Von Felten, A.² Gmur, J.³ Neftel, K.⁴

30
- 0028802468
- M. D. Tingle, H. Jewell, J. L. Maggs, P. M. O'Neill, B. K. Park, Biochem. Pharmacol. 1995, 50, 1113-1119.
- (1995) Biochem. Pharmacol. , vol.50 , pp. 1113-1119
- Tingle, M.D.¹ Jewell, H.² Maggs, J.L.³ O'Neill, P.M.⁴ Park, B.K.⁵

31
- 84859516990
- Z. Radic, R. K. Sit, Z. Kovarik, S. Berend, E. Garcia, L. Zhang, G. Amitai, C. Green, B. Radic, V. V. Fokin, K. B. Sharpless, P. Taylor, J. Biol. Chem. 2012, 287, 11798-11809.
- (2012) J. Biol. Chem. , vol.287 , pp. 11798-11809
- Radic, Z.¹ Sit, R.K.² Kovarik, Z.³ Berend, S.⁴ Garcia, E.⁵ Zhang, L.⁶ Amitai, G.⁷ Green, C.⁸ Radic, B.⁹ Fokin, V.V.¹⁰ Sharpless, K.B.¹¹ Taylor, P.¹²

32
- 84943348670
- M. Stojanovic, F. Katz, D. W. Landry, WO 2014210168, 2014;
- M. Stojanovic, F. Katz, D. W. Landry, WO 2014210168, 2014;

33
- 84943355479
- M. Stojanovic, F. Katz, D. W. Landry, WO 2014113495, 2014.
- M. Stojanovic, F. Katz, D. W. Landry, WO 2014113495, 2014.

34
- 0004075738
- 3 rd ed., Mosby, Edinburgh.
- J. W. Baynes, M. H. Dominiczak, Medical Biochemistry, 3 rd ed., Mosby, Edinburgh, 2009.
- (2009) Medical Biochemistry
- Baynes, J.W.¹ Dominiczak, M.H.²

35
- 70350214937
- C. Gilley, M. MacDonald, F. Nachon, L. M. Schopfer, J. Zhang, J. R. Cashman, O. Lockridge, Chem. Res. Toxicol. 2009, 22, 1680-1688.
- (2009) Chem. Res. Toxicol. , vol.22 , pp. 1680-1688
- Gilley, C.¹ MacDonald, M.² Nachon, F.³ Schopfer, L.M.⁴ Zhang, J.⁵ Cashman, J.R.⁶ Lockridge, O.⁷

36
- 84859050276
- E. C. Meek, H. W. Chambers, A. Coban, K. E. Funck, R. B. Pringle, M. K. Ross, J. E. Chambers, Toxicol. Sci. 2012, 126, 525-533;
- (2012) Toxicol. Sci. , vol.126 , pp. 525-533
- Meek, E.C.¹ Chambers, H.W.² Coban, A.³ Funck, K.E.⁴ Pringle, R.B.⁵ Ross, M.K.⁶ Chambers, J.E.⁷

37
- 0034908590
- W. S. Li, K. T. Lum, M. Chen-Goodspeed, M. A. Sogorb, F. M. Raushel, Bioorg. med. Chem. 2001, 9, 2083-2091.
- (2001) Bioorg. Med. Chem. , vol.9 , pp. 2083-2091
- Li, W.S.¹ Lum, K.T.² Chen-Goodspeed, M.³ Sogorb, M.A.⁴ Raushel, F.M.⁵

38
- 0344748240
- J. Epstein, H. O. Michel, D. H. Rosenblatt, R. E. Plapinger, R. A. Stephani, E. Cook, J. Am. Chem. Soc. 1964, 86, 4959-4963.
- (1964) J. Am. Chem. Soc. , vol.86 , pp. 4959-4963
- Epstein, J.¹ Michel, H.O.² Rosenblatt, D.H.³ Plapinger, R.E.⁴ Stephani, R.A.⁵ Cook, E.⁶

39
- 84872094975
- S. Muthukrishnan, V. S. Shete, T. T. Sanan, S. Vyas, S. Oottikkal, L. M. Porter, T. J. Magliery, C. M. Hadad, J. Phys. Org. Chem. 2012, 25, 1247-1260.
- (2012) J. Phys. Org. Chem. , vol.25 , pp. 1247-1260
- Muthukrishnan, S.¹ Shete, V.S.² Sanan, T.T.³ Vyas, S.⁴ Oottikkal, S.⁵ Porter, L.M.⁶ Magliery, T.J.⁷ Hadad, C.M.⁸

40
- 30444457741
- L. Briseno-Roa, J. Hill, S. Notman, D. Sellers, A. P. Smith, C. M. Timperley, J. Wetherell, N. H. Williams, G. R. Williams, A. R. Fersht, A. D. Griffiths, J. Med. Chem. 2006, 49, 246-255.
- (2006) J. Med. Chem. , vol.49 , pp. 246-255
- Briseno-Roa, L.¹ Hill, J.² Notman, S.³ Sellers, D.⁴ Smith, A.P.⁵ Timperley, C.M.⁶ Wetherell, J.⁷ Williams, N.H.⁸ Williams, G.R.⁹ Fersht, A.R.¹⁰ Griffiths, A.D.¹¹

41
- 0014597797
- W. N. Aldridge, E. Reiner, Biochem. J. 1969, 115, 147-162.
- (1969) Biochem. J. , vol.115 , pp. 147-162
- Aldridge, W.N.¹ Reiner, E.²

42
- 0030582428
- S. R. Hawley, P. G. Bray, P. M. O'Neill, B. K. Park, S. A. Ward, Biochem. Pharmacol. 1996, 52, 723-733;
- (1996) Biochem. Pharmacol. , vol.52 , pp. 723-733
- Hawley, S.R.¹ Bray, P.G.² O'Neill, P.M.³ Park, B.K.⁴ Ward, S.A.⁵

43
- 0043029927
- D. C. Warhurst, J. C. Steele, I. S. Adagu, J. C. Craig, C. Cullander, J. Antimicrob. Chemother. 2003, 52, 188-193.
- (2003) J. Antimicrob. Chemother. , vol.52 , pp. 188-193
- Warhurst, D.C.¹ Steele, J.C.² Adagu, I.S.³ Craig, J.C.⁴ Cullander, C.⁵

44
- 0023572245
- A. P. Kurtz, T. D. D'Silva, J. Pharm. Sci. 1987, 76, 599-610.
- (1987) J. Pharm. Sci. , vol.76 , pp. 599-610
- Kurtz, A.P.¹ D'Silva, T.D.²

45
- 78651299434
- M. Michaelides, N. B. Stover, P. J. Francis, R. G. Weleber, Arch. Ophthalmol. 2011, 129, 30-39.
- (2011) Arch. Ophthalmol. , vol.129 , pp. 30-39
- Michaelides, M.¹ Stover, N.B.² Francis, P.J.³ Weleber, R.G.⁴

46
- 34347361607
- A. Koreeda, K. Yonemitsu, H. Kohmatsu, S. Mimasaka, Y. Ohtsu, T. Oshima, K. Fujiwara, S. Tsunenari, Arch. Toxicol. 2007, 81, 471-478.
- (2007) Arch. Toxicol. , vol.81 , pp. 471-478
- Koreeda, A.¹ Yonemitsu, K.² Kohmatsu, H.³ Mimasaka, S.⁴ Ohtsu, Y.⁵ Oshima, T.⁶ Fujiwara, K.⁷ Tsunenari, S.⁸

47
- 35448978808
- C. Luo, M. Tong, N. Chilukuri, K. Brecht, D. M. Maxwell, A. Saxena, Biochemistry 2007, 46, 11771-11779;
- (2007) Biochemistry , vol.46 , pp. 11771-11779
- Luo, C.¹ Tong, M.² Chilukuri, N.³ Brecht, K.⁴ Maxwell, D.M.⁵ Saxena, A.⁶

48
- 1542533645
- Z. Kovarik, Z. Radic, H. A. Berman, V. Simeon-Rudolf, E. Reiner, P. Taylor, Biochemistry 2004, 43, 3222-3229;
- (2004) Biochemistry , vol.43 , pp. 3222-3229
- Kovarik, Z.¹ Radic, Z.² Berman, H.A.³ Simeon-Rudolf, V.⁴ Reiner, E.⁵ Taylor, P.⁶

49
- 0031694251
- F. Worek, P. Eyer, L. Szinicz, Arch. Toxicol. 1998, 72, 580-587;
- (1998) Arch. Toxicol. , vol.72 , pp. 580-587
- Worek, F.¹ Eyer, P.² Szinicz, L.³

50
- 0028355643
- D. M. Maxwell, C. N. Lieske, K. M. Brecht, Chem. Res. Toxicol. 1994, 7, 428-433.
- (1994) Chem. Res. Toxicol. , vol.7 , pp. 428-433
- Maxwell, D.M.¹ Lieske, C.N.² Brecht, K.M.³

51
- 33748544640
- E. H. Rydberg, B. Brumshtein, H. M. Greenblatt, D. M. Wong, D. Shaya, L. D. Williams, P. R. Carlier, Y. P. Pang, I. Silman, J. L. Sussman, J. Med. Chem. 2006, 49, 5491-5500;
- (2006) J. Med. Chem. , vol.49 , pp. 5491-5500
- Rydberg, E.H.¹ Brumshtein, B.² Greenblatt, H.M.³ Wong, D.M.⁴ Shaya, D.⁵ Williams, L.D.⁶ Carlier, P.R.⁷ Pang, Y.P.⁸ Silman, I.⁹ Sussman, J.L.¹⁰

52
- 33749402097
- Y. Bourne, Z. Radic, G. Sulzenbacher, E. Kim, P. Taylor, P. Marchot, J. Biol. Chem. 2006, 281, 29256-29267.
- (2006) J. Biol. Chem. , vol.281 , pp. 29256-29267
- Bourne, Y.¹ Radic, Z.² Sulzenbacher, G.³ Kim, E.⁴ Taylor, P.⁵ Marchot, P.⁶

53
- 0037015151
- H. Dvir, H. L. Jiang, D. M. Wong, M. Harel, M. Chetrit, X. C. He, G. Y. Jin, G. L. Yu, X. C. Tang, I. Silman, D. L. Bai, J. L. Sussman, Biochemistry 2002, 41, 10810-10818;
- (2002) Biochemistry , vol.41 , pp. 10810-10818
- Dvir, H.¹ Jiang, H.L.² Wong, D.M.³ Harel, M.⁴ Chetrit, M.⁵ He, X.C.⁶ Jin, G.Y.⁷ Yu, G.L.⁸ Tang, X.C.⁹ Silman, I.¹⁰ Bai, D.L.¹¹ Sussman, J.L.¹²

54
- 0033151759
- C. B. Millard, G. Kryger, A. Ordentlich, H. M. Greenblatt, M. Harel, M. L. Raves, Y. Segall, D. Barak, A. Shafferman, I. Silman, J. L. Sussman, Biochemistry 1999, 38, 7032-7039.
- (1999) Biochemistry , vol.38 , pp. 7032-7039
- Millard, C.B.¹ Kryger, G.² Ordentlich, A.³ Greenblatt, H.M.⁴ Harel, M.⁵ Raves, M.L.⁶ Segall, Y.⁷ Barak, D.⁸ Shafferman, A.⁹ Silman, I.¹⁰ Sussman, J.L.¹¹

55
- 33751171517
- M. Jokanovic, M. P. Stojiljkovic, Eur. J. Pharmacol. 2006, 553, 10-17;
- (2006) Eur. J. Pharmacol. , vol.553 , pp. 10-17
- Jokanovic, M.¹ Stojiljkovic, M.P.²

56
- 84882717699
- V. Sepsova, J. Z. Karasova, J. Korabecny, R. Dolezal, F. Zemek, B. J. Bennion, K. Kuca, Int. J. Mol. Sci. 2013, 14, 16882-16900.
- (2013) Int. J. Mol. Sci. , vol.14 , pp. 16882-16900
- Sepsova, V.¹ Karasova, J.Z.² Korabecny, J.³ Dolezal, R.⁴ Zemek, F.⁵ Bennion, B.J.⁶ Kuca, K.⁷

57
- 0026501542
- S. N. Dube, D. Kumar, A. K. Sikder, N. Sikder, D. K. Jaiswal, S. Das Gupta, Die Pharmazie 1992, 47, 68-69;
- (1992) Die Pharmazie , vol.47 , pp. 68-69
- Dube, S.N.¹ Kumar, D.² Sikder, A.K.³ Sikder, N.⁴ Jaiswal, D.K.⁵ Das Gupta, S.⁶

58
- 58149396330
- G. A. Petroianu, D. E. Lorke, Mini Reviews Med. Chem. 2008, 8, 1328-1342.
- (2008) Mini Reviews Med. Chem. , vol.8 , pp. 1328-1342
- Petroianu, G.A.¹ Lorke, D.E.²

59
- 81755173058
- E. G. Duysen, F. Koentgen, G. R. Williams, C. M. Timperley, L. M. Schopfer, D. M. Cerasoli, O. Lockridge, Chem. Res. Toxicol. 2011, 24, 1891-1898;
- (2011) Chem. Res. Toxicol. , vol.24 , pp. 1891-1898
- Duysen, E.G.¹ Koentgen, F.² Williams, G.R.³ Timperley, C.M.⁴ Schopfer, L.M.⁵ Cerasoli, D.M.⁶ Lockridge, O.⁷

60
- 0025005319
- D. M. Maxwell, I. Koplovitz, J. Pharmacol. Exp. Ther. 1990, 254, 440-444.
- (1990) J. Pharmacol. Exp. Ther. , vol.254 , pp. 440-444
- Maxwell, D.M.¹ Koplovitz, I.²

61
- 0021345926
- D. C. Dahlin, G. T. Miwa, A. Y. Lu, S. D. Nelson, Proc. Natl. Acad. Sci. USA 1984, 81, 1327-1331.
- (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 1327-1331
- Dahlin, D.C.¹ Miwa, G.T.² Lu, A.Y.³ Nelson, S.D.⁴

62
- 84878657720
- M. B. Colovic, D. Z. Krstic, T. D. Lazarevic-Pasti, A. M. Bondzic, V. M. Vasic, Curr Neuropharmacol. 2013, 11, 315-335.
- (2013) Curr Neuropharmacol. , vol.11 , pp. 315-335
- Colovic, M.B.¹ Krstic, D.Z.² Lazarevic-Pasti, T.D.³ Bondzic, A.M.⁴ Vasic, V.M.⁵

63
- 0030951065
- G. M. Tush, M. I. Anstead, Annals Pharmacother. 1997, 31, 441-444.
- (1997) Annals Pharmacother. , vol.31 , pp. 441-444
- Tush, G.M.¹ Anstead, M.I.²

64
- 84943365963
- ed. Masson Pub. USA, New York
- B. M. Mitruka, H. M. Rawnsley, Clinical Biochemical and Hematological Reference Values in Normal Experimental Animals and Normal Humans, 2nd ed., Masson Pub. USA, New York, 1981;
- (1981) Clinical Biochemical and Hematological Reference Values in Normal Experimental Animals and Normal Humans, 2nd
- Mitruka, B.M.¹ Rawnsley, H.M.²

65
- 84943362752
- J. Novotny, Vet. Med. Sm Anim. Clin. 1983, 78, 1130-1130.
- (1983) Vet. Med. Sm Anim. Clin. , vol.78 , pp. 1130-1130
- Novotny, J.¹

66
- 33644811612
- G. L. Ellman, K. D. Courtney, V. Andres, Jr., R. M. Feather-Stone, Biochem. Pharmacol. 1961, 7, 88-95.
- (1961) Biochem. Pharmacol. , vol.7 , pp. 88-95
- Ellman, G.L.¹ Courtney, K.D.² Andres Jr, . V.³ Feather-Stone, R.M.⁴

67
- 0030140312
- J. J. Ceron, M. J. Fernandex del Palacio, L. J. Bernal, C. Gutierrez, J. AOAC Int. 1996, 79, 757-763.
- (1996) J. AOAC Int. , vol.79 , pp. 757-763
- Ceron, J.J.¹ Fernandex Del Palacio, M.J.² Bernal, L.J.³ Gutierrez, C.⁴

68
- 70350101025
- K. Chen, S. Teo, K. Y. Seng, Toxicol. Mechanisms Methods 2009, 19, 486-497;
- (2009) Toxicol. Mechanisms Methods , vol.19 , pp. 486-497
- Chen, K.¹ Teo, S.² Seng, K.Y.³

69
- 0025604621
- J. M. Gearhart, G. W. Jepson, H. J. Clewell 3rd, M. E. Andersen, R. B. Conolly, Toxicol. Appl. Pharmacol. 1990, 106, 295-310.
- (1990) Toxicol. Appl. Pharmacol. , vol.106 , pp. 295-310
- Gearhart, J.M.¹ Jepson, G.W.² Clewell, H.J.³ Andersen, M.E.⁴ Conolly, R.B.⁵

70
- 50649103965
- P. Masson, F. Nachon, C. A. Broomfield, D. E. Lenz, L. Verdier, L. M. Schopfer, O. Lockridge, Chem.-Biol. Interact. 2008, 175, 273-280.
- (2008) Chem.-Biol. Interact. , vol.175 , pp. 273-280
- Masson, P.¹ Nachon, F.² Broomfield, C.A.³ Lenz, D.E.⁴ Verdier, L.⁵ Schopfer, L.M.⁶ Lockridge, O.⁷

71
- 84861166806
- M. Kokkinidis, N. M. Glykos, V. E. Fadouloglou, Adv. Protein Chem. 2012, 87, 181-218.
- (2012) Adv. Protein Chem. , vol.87 , pp. 181-218
- Kokkinidis, M.¹ Glykos, N.M.² Fadouloglou, V.E.³

72
- 0031059866
- Z. Otwinowski, W. Minor, Methods Enzymol. 1997, 276, 307-326.
- (1997) Methods Enzymol. , vol.276 , pp. 307-326
- Otwinowski, Z.¹ Minor, W.²

73
- 34247550159
- A. Hörnberg, A. K. Tunemalm, F. Ekström, Biochemistry 2007, 46, 4815-4825;
- (2007) Biochemistry , vol.46 , pp. 4815-4825
- Hörnberg, A.¹ Tunemalm, A.K.² Ekström, F.³

74
- 67650099505
- e
- F. Ekström, A. Hörnberg, E. Artursson, L.-G. Hammarström, G. Schneider, Y. P. Pang, PloS One 2009, 4, e 5957;
- (2009) PloS One , vol.4 , pp. 5957
- Ekström, F.¹ Hörnberg, A.² Artursson, E.³ Hammarström, L.-G.⁴ Schneider, G.⁵ Pang, Y.P.⁶

75
- 84871027166
- L. Berg, M. S. Niemiec, W. Qian, C. D. Andersson, P. Wittung-Stafshede, F. Ekström, A. Linusson, Angew. Chem. Int. Ed. 2012, 51, 12716-12720;
- (2012) Angew. Chem. Int. Ed. , vol.51 , pp. 12716-12720
- Berg, L.¹ Niemiec, M.S.² Qian, W.³ Andersson, C.D.⁴ Wittung-Stafshede, P.⁵ Ekström, F.⁶ Linusson, A.⁷

76
- 84943355016
- Angew. Chem. 2012, 124, 12888-12892;
- (2012) Angew. Chem. , vol.124 , pp. 12888-12892

77
- 84885571953
- C. D. Andersson, N. Forsgren, C. Akfur, A. Allgardsson, L. Berg, C. Engdahl, W. Qian, F. Ekström, A. Linusson, J. Med. Chem. 2013, 56, 7615-7624.
- (2013) J. Med. Chem. , vol.56 , pp. 7615-7624
- Andersson, C.D.¹ Forsgren, N.² Akfur, C.³ Allgardsson, A.⁴ Berg, L.⁵ Engdahl, C.⁶ Qian, W.⁷ Ekström, F.⁸ Linusson, A.⁹

78
- 0030924992
- G. N. Murshudov, A. A. Vagin, E. J. Dodson, Acta Crystallogr. Sect. D Biol. Crystallogr. 1997, 53, 240-255.
- (1997) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.53 , pp. 240-255
- Murshudov, G.N.¹ Vagin, A.A.² Dodson, E.J.³

79
- 84860273177
- P. V. Afonine, R. W. Grosse-Kunstleve, N. Echols, J. J. Headd, N. W. Moriarty, M. Mustyakimov, T. C. Terwilliger, A. Urzhumtsev, P. H. Zwart, P. D. Adams, Acta Crystallogr. Sect. D Biol. Crystallogr. 2012, 68, 352-367.
- (2012) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.68 , pp. 352-367
- Afonine, P.V.¹ Grosse-Kunstleve, R.W.² Echols, N.³ Headd, J.J.⁴ Moriarty, N.W.⁵ Mustyakimov, M.⁶ Terwilliger, T.C.⁷ Urzhumtsev, A.⁸ Zwart, P.H.⁹ Adams, P.D.¹⁰

80
- 13244281317
- P. Emsley, K. Cowtan, Acta Crystallogr. Sect. D Biol. Crystallogr. 2004, 60, 2126-2132.
- (2004) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.60 , pp. 2126-2132
- Emsley, P.¹ Cowtan, K.²

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