The role of drug accumulation in 4-aminoquinoline antimalarial potency. The influence of structural substitution and physicochemical properties

Biochemical Pharmacology

Volumn 52, Issue 5, 1996, Pages 723-733

  Hawley, Shaun R ^a   Bray, Patrick G ^a   O'Neill, Paul M ^a   Park, B Kevin ^a   Ward, Stephen A ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

4 aminoquinolines; accumulation; activity; amodiaquine; physicochemical properties; Plasmodium falciparum

Indexed keywords

AMODIAQUINE; ANTIMALARIAL AGENT; CHLOROQUINE; QUINOLINE DERIVATIVE; TEBUQUINE;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG RESISTANCE; LIPOPHILICITY; MATHEMATICS; NONHUMAN; PKA; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0030582428     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00354-1     Document Type: Article

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