Crystal structures of aged phosphonylated acetylcholinesterase: Nerve agent reaction products at the atomic level

Biochemistry

Volumn 38, Issue 22, 1999, Pages 7032-7039

  Millard, Charles B ^c   Kryger, Gitay ^a   Ordentlich, Arie ^b   Greenblatt, Harry M ^a   Harel, Michal ^a   Raves, Mia L ^a,d   Segall, Yoffi ^b   Barak, Dov ^b   Shafferman, Avigdor ^b   Silman, Israel ^a   Sussman, Joel L ^a,e  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^c U S ARMY   (United States)

^d UTRECHT UNIVERSITY   (Netherlands)

^e BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; DYFLOS; ORGANOPHOSPHORUS COMPOUND; SARIN; SOMAN;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONJUGATION; COVALENT BOND; CRYSTAL STRUCTURE; DEACYLATION; DEALKYLATION; ELECTRICITY; ENZYME INHIBITION; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; PHOSPHORYLATION; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

ACETYLCHOLINESTERASE; ACETYLTHIOCHOLINE; ACYLATION; ANIMALS; BINDING SITES; BUTYRYLTHIOCHOLINE; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; HYDROLYSIS; ISOFLUROPHATE; KINETICS; MODELS, MOLECULAR; SARIN; SOMAN; TORPEDO;

TORPEDO CALIFORNICA;

EID: 0033151759     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982678l     Document Type: Article

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