Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase

Chemical Research in Toxicology

Volumn 22, Issue 10, 2009, Pages 1680-1688

  Gilley, Cynthia ^a   MacDonald, Mary ^a   Nachon, Florian ^b   Schopfer, Lawrence M ^c   Zhang, Jun ^a   Cashman, John R ^a   Lockridge, Oksana ^c  

^a HUMAN BIOMOLECULAR RESEARCH INSTITUTE   (United States)

^b CENTRE DE RECHERCHES   (France)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORPROPHAM; CHOLINESTERASE; CYANIDE; CYCLOHEXYL METHYLPHOSPHONATE; FLUORINE; METHYLPHOSPHONIC ACID; NEUROTOXIN; ORGANOPHOSPHORUS COMPOUND; SARIN; SOMAN; TABUN; THIOCHOLINE; TRYPSIN; UNCLASSIFIED DRUG;

AGED; ARTICLE; CHEMICAL REACTION; HUMAN; ISOLATION PROCEDURE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PROTEIN ANALYSIS; PROTEIN PURIFICATION; STEREOISOMERISM;

AMINO ACID SEQUENCE; BUTYRYLCHOLINESTERASE; CATALYTIC DOMAIN; CHEMICAL WARFARE AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MOLECULAR SEQUENCE DATA; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDES; PHOSPHORIC ACID ESTERS; SARIN; SOMAN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THIOCHOLINE; TRYPSIN;

EID: 70350214937     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900090m     Document Type: Article

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