Chromatographic analysis of toxic phosphylated oximes (POX): A brief overview

Drug Testing and Analysis

Volumn 2, Issue 10, 2010, Pages 460-468

  Becker, Christian ^a   Worek, Franz ^a   John, Harald ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

Author keywords

chromatography; enzyme reactivation; nerve agents; organophosphorus compounds; oxime; pesticide; phosphylated oxime

Indexed keywords

AMINO ACIDS; ENZYME INHIBITION; ION CHROMATOGRAPHY; PHOSPHORUS COMPOUNDS; RATE CONSTANTS; THIN LAYER CHROMATOGRAPHY; TOXICITY;

ACETYLCHOLINESTERASE; ACTIVE SITE; ENZYME REACTIVATION; NERVE AGENTS; ORGANOPHOSPHORUS COMPOUNDS; OXIME; PHOSPHYLATED OXIME; QUARTER-NARY; SERINE RESIDUES; SYNAPTIC CLEFT;

PESTICIDES;

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 7 (METHYLETHOXY PHOSPHINYLOXY) 1 METHYL QUINOLINIUM; ACETYLCHOLINESTERASE; CYCLOSARIN; DYFLOS; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; OBIDOXIME; ORGANOPHOSPHORUS COMPOUND; PARAOXON; PRALIDOXIME; SARIN; TRIMEDOXIME; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; DRUG EFFICACY; DRUG INTOXICATION; DRUG PURIFICATION; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HYDROLYSIS; IN VITRO STUDY; INTOXICATION; ION PAIR CHROMATOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; REVIEW; STOICHIOMETRY; THIN LAYER CHROMATOGRAPHY;

EID: 78349249426     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.167     Document Type: Review

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