Enhancement of BACE1 activity by p25/Cdk5-mediated phosphorylation in Alzheimer's disease

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Song, Woo Joo ^a,b   Son, Mi Young ^b,e   Lee, Hye Won ^b   Seo, Hyemyung ^c   Kim, Jeong Hee ^d   Chung, Sul Hee ^a,b  

^a Kyung Hee University Hospital   (South Korea)

^b Inje University   (South Korea)

^c Hanyang University   (South Korea)

^d Kyung Hee University   (South Korea)

^e Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; CYCLIN DEPENDENT KINASE 5; PROTEIN P25; THREONINE; THREONINE 252; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; CDK5 PROTEIN, HUMAN; NERVE PROTEIN; P25 PROTEIN, HUMAN; SECRETASE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; AUTOPHAGOSOME; CONTROLLED STUDY; DEGENERATIVE DISEASE; DENSITY GRADIENT CENTRIFUGATION; ENZYME ACTIVITY; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MAMMAL CELL; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RISK FACTOR; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; BRAIN; CELL LINE; DISEASE MODEL; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CELL LINE; CYCLIN-DEPENDENT KINASE 5; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; PHOSPHORYLATION;

EID: 84943338852     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0136950     Document Type: Article

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