AMP-activated protein kinase suppresses arachidonate 15-lipoxygenase expression in interleukin 4-polarized human macrophages

Journal of Biological Chemistry

Volumn 290, Issue 40, 2015, Pages 24484-24494

  Namgaladze, Dmitry ^a   Snodgrass, Ryan G ^a   Angioni, Carlo ^a   Grossmann, Nina ^a   Dehne, Nathalie ^a   Geisslinger, Gerd ^a   Brüne, Bernhard ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; CHEMICAL ACTIVATION; ENZYME ACTIVITY; ENZYMES; GENES; PROTEINS;

AMP-ACTIVATED PROTEIN KINASE; ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY RESPONSE; INFLAMMATORY PROCESS; LIPOPOLYSACCHARIDES; MACROPHAGE PHENOTYPES; PRO-INFLAMMATORY CYTOKINES; PROTEIN EXPRESSIONS;

MACROPHAGES;

ALOX15 PROTEIN; AMINOIMIDAZOLE 4 CARBOXAMIDE 1 BETA RIBOFURANOSIDE; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID DERIVATIVE; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HISTONE H3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ACTIVATOR; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PHENFORMIN; STAT3 PROTEIN; STAT6 PROTEIN; UNCLASSIFIED DRUG; ALOX15 PROTEIN, HUMAN; ANTIINFLAMMATORY AGENT; CXCL10 PROTEIN, HUMAN; CXCL9 PROTEIN, HUMAN; IL12A PROTEIN, HUMAN; IL4 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; INTERLEUKIN 12P35; SMALL INTERFERING RNA; STAT3 PROTEIN, HUMAN;

ALOX15 GENE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REPRESSION; GENE INACTIVATION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; CHEMISTRY; CYTOLOGY; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INFLAMMATION; METABOLISM; MONOCYTE; PHAGOCYTE; PHENOTYPE; TIME FACTOR;

AMP-ACTIVATED PROTEIN KINASES; ANTI-INFLAMMATORY AGENTS; ARACHIDONATE 15-LIPOXYGENASE; CHEMOKINE CXCL10; CHEMOKINE CXCL9; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INFLAMMATION; INTERLEUKIN-12 SUBUNIT P35; INTERLEUKIN-4; INTERLEUKIN-6; MACROPHAGES; MONOCYTES; PHAGOCYTES; PHENOTYPE; RNA, SMALL INTERFERING; STAT3 TRANSCRIPTION FACTOR; TIME FACTORS;

EID: 84943224488     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.678243     Document Type: Article

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