-
2
-
-
0029829533
-
Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development
-
Shen J., Herderick E., Cornhill J.F., et al. Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development. J Clin Invest 1996, 98:2201-2208.
-
(1996)
J Clin Invest
, vol.98
, pp. 2201-2208
-
-
Shen, J.1
Herderick, E.2
Cornhill, J.F.3
-
3
-
-
0029611387
-
Transgenic rabbits with the integrated human 15-lipoxygenase gene driven by a lysozyme promoter: macrophage-specific expression and variable positional specificity of the transgenic enzyme
-
Shen J., Kuhn H., Petho-Schramm A., Chan L. Transgenic rabbits with the integrated human 15-lipoxygenase gene driven by a lysozyme promoter: macrophage-specific expression and variable positional specificity of the transgenic enzyme. FASEB J 1995, 9:1623-1631.
-
(1995)
FASEB J
, vol.9
, pp. 1623-1631
-
-
Shen, J.1
Kuhn, H.2
Petho-Schramm, A.3
Chan, L.4
-
4
-
-
0032752579
-
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice
-
Cyrus T., Witztum J.L., Rader D.J., et al. Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J Clin Invest 1999, 103:1597-1604.
-
(1999)
J Clin Invest
, vol.103
, pp. 1597-1604
-
-
Cyrus, T.1
Witztum, J.L.2
Rader, D.J.3
-
5
-
-
20844446795
-
Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice
-
Huo Y., Zhao L., Hyman M.C., et al. Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice. Circulation 2004, 110:2024-2031.
-
(2004)
Circulation
, vol.110
, pp. 2024-2031
-
-
Huo, Y.1
Zhao, L.2
Hyman, M.C.3
-
6
-
-
0033812812
-
Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice
-
Harats D., Shaish A., George J., et al. Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 2000, 20:2100-2105.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2100-2105
-
-
Harats, D.1
Shaish, A.2
George, J.3
-
7
-
-
54049137639
-
Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators
-
Merched A.J., Ko K., Gotlinger K.H., Serhan C.N., Chan L. Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators. Faseb J 2008, 22:3595-3606.
-
(2008)
Faseb J
, vol.22
, pp. 3595-3606
-
-
Merched, A.J.1
Ko, K.2
Gotlinger, K.H.3
Serhan, C.N.4
Chan, L.5
-
8
-
-
79953706626
-
Nutrigenetic disruption of inflammation-resolution homeostasis and atherogenesis
-
Merched A.J., Serhan C.N., Chan L. Nutrigenetic disruption of inflammation-resolution homeostasis and atherogenesis. J Nutrigenet Nutrigenomics 2011, 4:12-24.
-
(2011)
J Nutrigenet Nutrigenomics
, vol.4
, pp. 12-24
-
-
Merched, A.J.1
Serhan, C.N.2
Chan, L.3
-
9
-
-
34247357016
-
The c.-292C>T promoter polymorphism increases reticulocyte-type 15-lipoxygenase-1 activity and could be atheroprotective
-
Wittwer J., Bayer M., Mosandl A., Muntwyler J., Hersberger M. The c.-292C>T promoter polymorphism increases reticulocyte-type 15-lipoxygenase-1 activity and could be atheroprotective. Clin Chem Lab Med 2007, 45:487-492.
-
(2007)
Clin Chem Lab Med
, vol.45
, pp. 487-492
-
-
Wittwer, J.1
Bayer, M.2
Mosandl, A.3
Muntwyler, J.4
Hersberger, M.5
-
10
-
-
40949164339
-
A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease
-
Assimes T.L., Knowles J.W., Priest J.R., et al. A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. Atherosclerosis 2008, 198:136-144.
-
(2008)
Atherosclerosis
, vol.198
, pp. 136-144
-
-
Assimes, T.L.1
Knowles, J.W.2
Priest, J.R.3
-
11
-
-
67349191171
-
No association of two functional polymorphisms in human ALOX15 with myocardial infarction
-
Hersberger M., Muller M., Marti-Jaun J., et al. No association of two functional polymorphisms in human ALOX15 with myocardial infarction. Atherosclerosis 2009, 205:192-196.
-
(2009)
Atherosclerosis
, vol.205
, pp. 192-196
-
-
Hersberger, M.1
Muller, M.2
Marti-Jaun, J.3
-
12
-
-
77955454197
-
Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins
-
Hersberger M. Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins. Clin Chem Lab Med 2010, 48:1063-1073.
-
(2010)
Clin Chem Lab Med
, vol.48
, pp. 1063-1073
-
-
Hersberger, M.1
-
13
-
-
20844462708
-
Hypoxia increases LDL oxidation and expression of 15-lipoxygenase-2 in human macrophages
-
Rydberg E.K., Krettek A., Ullstrom C., et al. Hypoxia increases LDL oxidation and expression of 15-lipoxygenase-2 in human macrophages. Arterioscler Thromb Vasc Biol 2004, 24:2040-2045.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 2040-2045
-
-
Rydberg, E.K.1
Krettek, A.2
Ullstrom, C.3
-
14
-
-
74049111313
-
15-Lipoxygenase-2 is expressed in macrophages in human carotid plaques and regulated by hypoxia-inducible factor-1alpha
-
Hulten L.M., Olson F.J., Aberg H., et al. 15-Lipoxygenase-2 is expressed in macrophages in human carotid plaques and regulated by hypoxia-inducible factor-1alpha. Eur J Clin Invest 2010, 40:11-17.
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 11-17
-
-
Hulten, L.M.1
Olson, F.J.2
Aberg, H.3
-
15
-
-
79953047839
-
12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms
-
Gertow K., Nobili E., Folkersen L., et al. 12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms. Atherosclerosis 2011, 215:411-416.
-
(2011)
Atherosclerosis
, vol.215
, pp. 411-416
-
-
Gertow, K.1
Nobili, E.2
Folkersen, L.3
-
16
-
-
20344365594
-
Gene expression alterations of human peripheral blood monocytes induced by medium-term treatment with the TH2-cytokines interleukin-4 and -13
-
Chaitidis P., O'Donnell V., Kuban R.J., Bermudez-Fajardo A., Ungethuem U., Kuhn H. Gene expression alterations of human peripheral blood monocytes induced by medium-term treatment with the TH2-cytokines interleukin-4 and -13. Cytokine 2005, 30:366-377.
-
(2005)
Cytokine
, vol.30
, pp. 366-377
-
-
Chaitidis, P.1
O'Donnell, V.2
Kuban, R.J.3
Bermudez-Fajardo, A.4
Ungethuem, U.5
Kuhn, H.6
-
17
-
-
18544364362
-
Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells
-
Tang S., Bhatia B., Maldonado C.J., et al. Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem 2002, 277:16189-16201.
-
(2002)
J Biol Chem
, vol.277
, pp. 16189-16201
-
-
Tang, S.1
Bhatia, B.2
Maldonado, C.J.3
-
18
-
-
38449102676
-
Macrophage activation and polarization
-
Martinez F.O., Sica A., Mantovani A., Locati M. Macrophage activation and polarization. Front Biosci 2008, 13:453-461.
-
(2008)
Front Biosci
, vol.13
, pp. 453-461
-
-
Martinez, F.O.1
Sica, A.2
Mantovani, A.3
Locati, M.4
-
19
-
-
33750813483
-
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
-
Martinez F.O., Gordon S., Locati M., Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 2006, 177:7303-7311.
-
(2006)
J Immunol
, vol.177
, pp. 7303-7311
-
-
Martinez, F.O.1
Gordon, S.2
Locati, M.3
Mantovani, A.4
-
20
-
-
80052761810
-
Macrophage polarization in metabolic disorders: functions and regulation
-
Chinetti-Gbaguidi G., Staels B. Macrophage polarization in metabolic disorders: functions and regulation. Curr Opin Lipidol 2011, 22:365-372.
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 365-372
-
-
Chinetti-Gbaguidi, G.1
Staels, B.2
-
21
-
-
34547492488
-
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
Bouhlel M.A., Derudas B., Rigamonti E., et al. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab 2007, 6:137-143.
-
(2007)
Cell Metab
, vol.6
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
-
22
-
-
79954802715
-
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARgamma and LXRalpha pathways
-
Chinetti-Gbaguidi G., Baron M., Bouhlel M.A., et al. Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARgamma and LXRalpha pathways. Circ Research 2011, 108:985-995.
-
(2011)
Circ Research
, vol.108
, pp. 985-995
-
-
Chinetti-Gbaguidi, G.1
Baron, M.2
Bouhlel, M.A.3
-
23
-
-
80355131976
-
Protective and pathogenic functions of macrophage subsets
-
Murray P.J., Wynn T.A. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol 2011, 11:723-737.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 723-737
-
-
Murray, P.J.1
Wynn, T.A.2
-
25
-
-
0027247808
-
Overexpression, purification and characterization of human recombinant 15-lipoxygenase
-
Kuhn H., Barnett J., Grunberger D., et al. Overexpression, purification and characterization of human recombinant 15-lipoxygenase. Biochim Biophys Acta 1993, 1169:80-89.
-
(1993)
Biochim Biophys Acta
, vol.1169
, pp. 80-89
-
-
Kuhn, H.1
Barnett, J.2
Grunberger, D.3
-
26
-
-
0033571064
-
Differential characteristics of human 15-lipoxygenase isozymes and a novel splice variant of 15S-lipoxygenase
-
Kilty I., Logan A., Vickers P.J. Differential characteristics of human 15-lipoxygenase isozymes and a novel splice variant of 15S-lipoxygenase. Eur J Biochem 1999, 266:83-93.
-
(1999)
Eur J Biochem
, vol.266
, pp. 83-93
-
-
Kilty, I.1
Logan, A.2
Vickers, P.J.3
-
27
-
-
0028876377
-
Induction of 15-lipoxygenase mRNA and protein in early atherosclerotic lesions
-
Hiltunen T., Luoma J., Nikkari T., Yla-Herttuala S. Induction of 15-lipoxygenase mRNA and protein in early atherosclerotic lesions. Circulation 1995, 92:3297-3303.
-
(1995)
Circulation
, vol.92
, pp. 3297-3303
-
-
Hiltunen, T.1
Luoma, J.2
Nikkari, T.3
Yla-Herttuala, S.4
-
28
-
-
0025076921
-
Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions
-
Yla-Herttuala S., Rosenfeld M.E., Parthasarathy S., et al. Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions. Proc Natl Acad Sci U S A 1990, 87:6959-6963.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 6959-6963
-
-
Yla-Herttuala, S.1
Rosenfeld, M.E.2
Parthasarathy, S.3
-
29
-
-
0028234336
-
Involvement of 15-lipoxygenase in early stages of atherogenesis
-
Kuhn H., Belkner J., Zaiss S., Fahrenklemper T., Wohlfeil S. Involvement of 15-lipoxygenase in early stages of atherogenesis. J Exp Med 1994, 179:1903-1911.
-
(1994)
J Exp Med
, vol.179
, pp. 1903-1911
-
-
Kuhn, H.1
Belkner, J.2
Zaiss, S.3
Fahrenklemper, T.4
Wohlfeil, S.5
-
30
-
-
0029013214
-
Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein
-
Yla-Herttuala S., Luoma J., Viita H., Hiltunen T., Sisto T., Nikkari T. Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein. J Clin Invest 1995, 95:2692-2698.
-
(1995)
J Clin Invest
, vol.95
, pp. 2692-2698
-
-
Yla-Herttuala, S.1
Luoma, J.2
Viita, H.3
Hiltunen, T.4
Sisto, T.5
Nikkari, T.6
-
31
-
-
0025897282
-
Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts
-
Yla-Herttuala S., Rosenfeld M.E., Parthasarathy S., et al. Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts. J Clin Invest 1991, 87:1146-1152.
-
(1991)
J Clin Invest
, vol.87
, pp. 1146-1152
-
-
Yla-Herttuala, S.1
Rosenfeld, M.E.2
Parthasarathy, S.3
-
32
-
-
0344145871
-
In vivo action of 15-lipoxygenase in early stages of human atherogenesis
-
Kuhn H., Heydeck D., Hugou I., Gniwotta C. In vivo action of 15-lipoxygenase in early stages of human atherogenesis. J Clin Invest 1997, 99:888-893.
-
(1997)
J Clin Invest
, vol.99
, pp. 888-893
-
-
Kuhn, H.1
Heydeck, D.2
Hugou, I.3
Gniwotta, C.4
-
33
-
-
0037417973
-
Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis
-
Spanbroek R., Grabner R., Lotzer K., et al. Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis. Proc Natl Acad Sci U S A 2003, 100:1238-1243.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1238-1243
-
-
Spanbroek, R.1
Grabner, R.2
Lotzer, K.3
-
34
-
-
29944436523
-
Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1
-
Wittwer J., Marti-Jaun J., Hersberger M. Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1. Hum Mutat 2006, 27:78-87.
-
(2006)
Hum Mutat
, vol.27
, pp. 78-87
-
-
Wittwer, J.1
Marti-Jaun, J.2
Hersberger, M.3
|