Comprehensive analysis of TLR4-induced transcriptional responses in interleukin 4-primed mouse macrophages

Immunobiology

Volumn 215, Issue 9-10, 2010, Pages 780-787

  El Chartouni, Carol ^a   Rehli, Michael ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Alternative macrophage activation; Gene regulation; Toll like receptor

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; EOTAXIN 2; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON; INTERLEUKIN 12P35; INTERLEUKIN 19; INTERLEUKIN 4; MACROPHAGE DERIVED CHEMOKINE; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE ACTIVATION; GENE INDUCTION; GENE REPRESSION; GENETIC TRANSCRIPTION; INFLAMMATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGEN PRESENTATION; CELLS, CULTURED; ENDOCYTOSIS; GENE EXPRESSION PROFILING; IMMUNIZATION; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; STAT1 TRANSCRIPTION FACTOR; TH1-TH2 BALANCE; TOLL-LIKE RECEPTOR 4; TRANSCRIPTIONAL ACTIVATION;

EID: 77955417711     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2010.05.032     Document Type: Article

References (23)

1. Bogdan C., Moll H., Solbach W., Rollinghoff M. Tumor necrosis factor-alpha in combination with interferon-gamma, but not with interleukin 4 activates murine macrophages for elimination of Leishmania major amastigotes. Eur. J. Immunol. 1990, 20:1131-1135.
2. Bogdan C., Stenger S., Rollinghoff M., Solbach W. Cytokine interactions in experimental cutaneous leishmaniasis. Interleukin 4 synergizes with interferon-gamma to activate murine macrophages for killing of Leishmania major amastigotes. Eur. J. Immunol. 1991, 21:327-333.
3. Bogdan C., Vodovotz Y., Paik J., Xie Q.W., Nathan C. Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages. J. Leukoc. Biol. 1994, 55:227-233.
4. Corraliza I.M., Soler G., Eichmann K., Modolell M. Arginase induction by suppressors of nitric oxide synthesis (IL-4, IL-10 and PGE2) in murine bone-marrow-derived macrophages. Biochem. Biophys. Res. Commun. 1995, 206:667-673.
5. Durbin J.E., Hackenmiller R., Simon M.C., Levy D.E. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 1996, 84:443-450.
6. El Chartouni C., Benner C., Eigner M., Lichtinger M., Rehli M. Transcriptional effects of colony-stimulating factor-1 in mouse macrophages. Immunobiology 2010, 215:466-474.
7. Ghassabeh G.H., De Baetselier P., Brys L., Noel W., Van Ginderachter J.A., Meerschaut S., Beschin A., Brombacher F., Raes G. Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Blood 2006, 108:575-583.
8. Goerdt S., Orfanos C.E. Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 1999, 10:137-142.
9. Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 2003, 3:23-35.
10. Gordon S., Taylor P.R. Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 2005, 5:953-964.
11. Gratchev A., Kzhyshkowska J., Kothe K., Muller-Molinet I., Kannookadan S., Utikal J., Goerdt S. Mphi1 and Mphi2 can be re-polarized by Th2 or Th1 cytokines, respectively, and respond to exogenous danger signals. Immunobiology 2006, 211:473-486.
12. Hume D.A. Differentiation and heterogeneity in the mononuclear phagocyte system. Mucosal. Immunol. 2008, 1:432-441.
13. Ishii M., Wen H., Corsa C.A., Liu T., Coelho A.L., Allen R.M., Carson W.F., Cavassani K.A., Li X., Lukacs N.W., Hogaboam C.M., Dou Y., Kunkel S.L. Epigenetic regulation of the alternatively activated macrophage phenotype. Blood 2009, 114:3244-3254.
14. Kahnert A., Seiler P., Stein M., Bandermann S., Hahnke K., Mollenkopf H., Kaufmann S.H. Alternative activation deprives macrophages of a coordinated defense program to Mycobacterium tuberculosis. Eur. J. Immunol. 2006, 36:631-647.
15. Major J., Fletcher J.E., Hamilton T.A. IL-4 pretreatment selectively enhances cytokine and chemokine production in lipopolysaccharide-stimulated mouse peritoneal macrophages. J. Immunol. 2002, 168:2456-2463.
16. Martinez F.O., Gordon S., Locati M., Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 2006, 177:7303-7311.
17. Martinez F.O., Helming L., Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu. Rev. Immunol. 2009, 27:451-483.
18. Rehli M., Sulzbacher S., Pape S., Ravasi T., Wells C.A., Heinz S., Sollner L., El Chartouni C., Krause S.W., Steingrimsson E., Hume D.A., Andreesen R. Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor. J. Immunol. 2005, 174:7111-7122.
19. Schilling E., El Chartouni C., Rehli M. Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences. Genome Res. 2009, 19:2028-2035.
20. Stein M., Keshav S., Harris N., Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 1992, 176:287-292.
21. Stout R.D., Jiang C., Matta B., Tietzel I., Watkins S.K., Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J. Immunol. 2005, 175:342-349.
22. Stout R.D., Suttles J. Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J. Leukoc. Biol. 2004, 76:509-513.
23. Xie Q.W., Cho H.J., Calaycay J., Mumford R.A., Swiderek K.M., Lee T.D., Ding A., Troso T., Nathan C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992, 256:225-228.