AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)

Diabetologia

Volumn 53, Issue 11, 2010, Pages 2406-2416

  Nerstedt, A ^a   Johansson, A ^a   Andersson, C X ^a   Cansby, E ^a   Smith, U ^a   Mahlapuu, M ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

AMP activated protein kinase; Inflammation; Interleukin 6; Liver; Type 2 diabetes

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; HAPTOGLOBIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 6; METFORMIN; SERUM AMYLOID A; SMALL INTERFERING RNA; STAT3 PROTEIN;

ACUTE PHASE RESPONSE; ARTICLE; CELL STRAIN HEPG2; CHRONIC INFLAMMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; LIVER CELL; METABOLIC REGULATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYPOGLYCEMIC AGENTS; INTERLEUKIN-6; LIVER; METFORMIN; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEOTIDES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 77957653461     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1856-z     Document Type: Article

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